Derivatives of 1,3-diones having a herbicidal activity

ABSTRACT

A description follows of 1,3-diones having general formula (I): together with their use as herbicides for the control of weeds in agricultural crops.

The present invention relates to derivatives of 1,3-diones having a herbicidal activity.

The invention also relates to processes for the preparation of the above derivatives of 1,3-diones and their use as herbicides for the control of weeds in agricultural crops.

Various derivatives of 1,3-diones substituted in position 1 and 2 by aromatic and/or heteroaromatic groups are described in J. Indian. Chem. Soc. (1961), vol. 38, pages 343-345, J. Org. Chem. (1962), vol. 27, pages 1899-1901 and Tetrahedron (1963), vol. 19, pages 413-418.

A herbicidal activity has never been described for any of these compounds.

The Applicant has now surprisingly found that derivatives of 1,3-diones, in which the substituents in position 1 and 2 represent suitably substituted aryl, heteroaryl or heterocyclic groups, have a high herbicidal activity with respect to weeds in crops of agrarian interest.

An object of the present invention therefore relates to derivatives of 1,3-diones having general formula (I):

wherein:

-   A represents: -   an aryl group optionally substituted by one or more substituents     selected from halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆     alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆     alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl,     C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl,     C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆     haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆     haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆     haloalkoxyalkoxyl optionally substituted with a group selected from     C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆     haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl,     C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆     haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl,     C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈     alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆     haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈     alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂     acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl,     C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈     alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀     alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂     dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃,     —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃,     —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂,     -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄,     —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆,     -Z₂(CR₃₄R₃₅)_(p)(C═Y)T. -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; -   or it represents a heterocyclic group selected from pyridyl,     pyrimidyl, quinolinyl, pyrazolyl, thiazolyl, oxazolyl, thienyl,     furyl, benzothienyl, dihydrobenzothienyl, benzofuranyl,     dihydrobenzofuranyl, benzoxazolyl, benzoxazolonyl, benzothiazolyl,     benzothiazolonyl, benzoimidazolyl, benzoimidazolonyl,     benzotriazolyl, chromanonyl, chromanyl, thiochromanonyl,     thiochromanyl, 3a,4-dihydro-3H-indeno[1,2-c]isoxazolyl,     3a,4-dihydro-3H-chromeno[4,3-c]isoxazolyl,     5,5-dioxide-3a,4-dihydro-3H-thiochromeno[4,3-c]isoxazolyl,     2,3,3a,4-tetrahydrochromeno[4,3-c]pyrazolyl,     6,6-dioxide-2,3-dihydro-5H-[1,4]dithiino[2,3-c]thiochromenyl,     5,5-dioxide-2,3,3a,4-tetrahydrothiochromeno[4,3-c]pyrazolyl,     1′,1′-dioxide-2′,3′-dihydrospiro[1,3-dioxolano-2,4′-thiochromen]-yl,     1,1,4,4-tetraoxide-2,3-dihydro-1,4-benzodithiin-6-yl,     4,4-dioxide-2,3-dihydro-1,4-benzoxathiin-7-yl,     1,1-dioxide-3-oxo-2,3-dihydro-1,2-benzoisothiazol-5-yl,     4-(alkoxyimino)-1,1-dioxide-3,4-dihydro-2H-thiochromen-6-yl,     1,1-dioxide-4-oxo-3,4-dihydro-2H-thiochromen-6-yl,     2,3-dihydro-1,4-benzoxathiin-7-yl, -   with said groups optionally substituted by one or more substituents     selected from halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆     alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆     alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl,     C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl,     C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆     haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆     haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆     haloalkoxyalkoxyl optionally substituted with a group selected from     C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆     haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl,     C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆     haloalkoxyhaloalkoxyl, C₃-C₁o alkoxyalkoxyalkyl, C₂-C₆ alkenyl,     C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈     alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆     haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈     alkynyloxyalkoxyl, C₃C₈ haloalkynyloxyalkoxyl, C₃-C₁₂     acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl,     C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈     alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀     alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂     dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃,     —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃,     —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂,     -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄,     —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆,     -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; -   B represents a D-(R_(x))_(n) group; -   R represents a hydrogen atom, a linear or branched C₁-C₆ alkyl     group, a linear or branched C₁-C₆ haloalkyl group, a C₃-C₆     cycloalkyl or C₄-C₁₂ cycloalkylalkyl group optionally substituted     with halogen atoms or C₁-C₆ alkyl or C₁-C₆ thioalkyl or C₁-C₆     alkoxyl or C₂-C₆ alkoxycarbonyl groups, C₂-C₆ alkenyl groups, C₂-C₆     alkynyl groups, the latter two groups, in turn, optionally     substituted with halogen atoms, a C₅-C₆ cycloalkenyl group     optionally substituted with halogen atoms or C₁-C₆ alkyl groups, an     aryl or arylalkyl group optionally substituted; -   R₁ and R₁₉ represent a C₁-C₆ alkyl group or a C₁-C₆ haloalkyl group,     a C₃-C₆ cycloalkyl group, an aryl group optionally substituted by     one or more substituents selected from halogen, NO₂, CN, CHO, linear     or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear     or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl,     C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl; -   m is equal to 0, 1 or 2; -   t is equal to 1 or 2; -   R₂, R₃, R₆, R₇, R₈, R₉, R₁₀, R₁₁, R₁₇ and R₁₈, the same or     different, represent a hydrogen atom, a linear or branched C₁-C₆     alkyl group in turn optionally substituted with halogen atoms, a     C₁-C₆ alkoxyl group, a C₃-C₆ cycloalkyl group, an arylalkyl group or     an aryl group, said arylalkyl and aryl groups also optionally     substituted by one or more substituents selected from halogen, NO₂,     CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆     haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched     C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl, or     they jointly represent a C₂-C₅ alkylene group; -   R₄, R₅ and R₄₂ represent a hydrogen atom, a linear or branched C₁-C₆     alkyl group in turn optionally substituted with halogen atoms, a     C₃-C₆ alkenyl group in turn optionally substituted with halogen     atoms, a Q₇ group, an arylalkyl group optionally substituted by one     or more substituents selected from halogen, NO₂, CN, CHO, linear or     branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or     branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆     alkylsulfonyl, C₂-C₆ alkoxycarbonyl; -   R₁₂, R₁₄ and R₁₆ represent a hydrogen atom, a linear or branched     C₁-C₆ alkyl group in turn optionally substituted with halogen atoms,     a C₃-C₆ cycloalkyl group, a C₁-C₆ alkoxyl group, a C₁-C₆ haloalkoxyl     group; -   R₁₃ and R₁₅ represent a hydrogen atom, a linear or branched C₁-C₆     alkyl group in turn optionally substituted with halogen atoms, a     C₃-C₆ alkenyl group in turn optionally substituted with halogen     atoms, a Q₇, NH₂, NHCN, NHNH₂, NHOH group, an arylalkyl group     optionally substituted by one or more substituents selected from     halogen, NO₂, CN, CHO, linear or branched C₃-C₆ alkyl, linear or     branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear     or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆     alkoxycarbonyl; -   R₂₀, R₂₁, R₂₂, R₂₃, R₂₄, R₂₅, R₂₆, R₂₇, R₂₈, R₂₉, R₃₀, R₃₁, R₃₂,     R₃₃, R₃₄, R₃₅, R₃₆, R₃₇, R₃₈, R₃₉, R₄₀ and R₄₁, the same or     different, represent a hydrogen atom, a linear or branched C₁-C₆     alkyl group in turn optionally substituted with halogen atoms, a     C₁-C₆ alkoxyl group, or the two groups attached to the same carbon     atom can be joined to each other by C₂-C₅ alkylene groups, the     alkylene groups can in turn be substituted with C₁-C₃ alkyl groups; -   Q, Q₁, Q₂, Q₃, Q₄, Q₅, Q₆ and Q₇ represent an aryl group, a C₃-C₆     cycloalkyl group, a C₅-C₆ cycloalkenyl group, a heterocyclic group     selected from triazolyl, triazolonyl, pyrazolyl, imidazolyl,     imidazolidinonyl, tetrazolyl, tetrazolonyl, isoxazolyl, furyl,     thienyl, pyrrolyl, pyrrolidinyl, pyrrolidinonyl, pyridyl,     pyrimidinyl, pyrimidinonyl, pyrazinyl, pyridazinyl, oxazolyl,     thiazolyl, oxadiazolyl, thiadiazolyl, isothiazolyl, benzoxazolyl,     benzothiazolyl, isoxazolinyl, 1,3-dioxanyl, 1,4-dioxanyl,     1,3-dioxolanyl, tetrahydropyranyl, oxethanyl, oxyranyl,     thiazolidinyl, oxazolidinyl, piperidinyl, piperidinonyl,     piperazinyl, morpholinyl, thiazinyl, tetrahydrofuranyl, dioxazolyl,     tetrahydrofuroisoxazolyl, 2-oxa-3-azabicyclo[3.1.0]hex-3-enyl, -   said groups optionally substituted by one or more substituents     selected from halogen, NO₂, OH, CN, CHO, linear or branched C₁-C₆     alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₃-C₆     alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl,     C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl,     C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆     haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆     haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆     haloalkoxyalkoxyl optionally substituted with a group selected from     C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆     haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl,     C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆     haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl,     C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈     alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆     haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈     alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂     acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl,     C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈     alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀     alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂     dialkylideneiminooxyalkyl, aryl optionally substituted, —S(O)_(m)R₁,     —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉,     —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂,     -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; -   Z, Z₁, Z₂=O, S(O)_(r); -   Y═O, S; -   r is equal to 0, 1 or 2; -   p, q are equal to 1, 2, 3 or 4; -   v is equal to 0 or 1; -   Z₃=O, S or a direct bond; -   T represents a hydrogen atom, a Z₄R₄₂ group, a —NR₄₃R₄₄ group, an     aryl group or a heterocyclic group selected from triazolyl,     triazolonyl, pyrazolyl, imidazolyl, imidazolidinonyl, tetrazolyl,     tetrazolonyl, pyrrolyl, pyrrolidinyl, pyrrolidinonyl, pyridyl,     pyrimidinyl, piperidinyl, piperidinonyl, piperazinyl, morpholinyl,     said groups optionally substituted by one or more substituents     selected from halogen, NO₂, OH, CN, CHO, linear or branched C₁-C₆     alkyl, linear or branched C₁-C₆ haloalkyl, C₃-C₆ cycloalkyl, C₅-C₆     cycloalkenyl, linear or branched C₁-C₆ alkoxyl, linear or branched     C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆     alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl,     C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆     haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, —S(O)_(m)R₁; -   Z₄=O, S or a direct bond; -   R₄₃ and R₄₄, the same or different, represent a hydrogen atom, a     linear or branched C₁-C₆ alkyl group in turn optionally substituted     with halogen atoms, a C₃-C₆ alkenyl group in turn optionally     substituted with halogen atoms, a Q₇ group, an arylalkyl group     optionally substituted by one or more substituents selected from     halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or     branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear     or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆     alkoxycarbonyl, or they jointly represent a C₂-C₅ alkylene chain; -   D represents: -   a heterocyclic group of the heteroaryl or heterocyclic type, in all     the above cases the heterocycle can be mono or polycyclic and can be     connected to the rest of the structure either through one of its     carbon atoms or, when possible, through one of its nitrogen atoms; -   or it represents a mono or polycyclic aryl group, in this latter     case, the group can also be partially saturated; -   R_(x) represents a substituent selected from hydrogen, halogen, NO₂,     CN, CHO, OH, linear or branched C₁-C₆ alkyl, linear or branched     C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or     branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl,     C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆     alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl,     C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆     alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl optionally substituted with     a group selected from C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆     haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl,     C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆     haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl,     C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈     alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆     haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈     alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂     acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl,     C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈     alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀     alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂     dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃,     —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃,     —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂,     -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄,     —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆,     -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; -   if several R, groups are present, these can be the same or     different; -   n=1-9; -   excluding the following compounds having general formula (I) wherein     A, B and R have the following meanings: -   A=4-chlorophenyl, B=1-methylimidazol-2-yl, R═H; -   A=4-nitrophenyl, B=1-(2-hydroxyethyl)-5-nitroimidazol-2-yl, R═H; -   A=phenyl, B-1H-benzimidazol-2-yl, R═C₂H₅; -   A=phenyl, B=4H-1-benzopyran-4-yl, R═CH₃; -   A=4-nitrophenyl, B=3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl, R═CH₃; -   A=phenyl, B=4-chloro-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl, R═CH₃; -   A=phenyl, B=2-acetyl-1,2,3,4-tetrahydroisoquinolin-1-yl, R═C₂H₅; -   A=2-hydroxy-4-methoxyphenyl, B=thiazol-4-yl, R═CH₃; -   A=phenyl, B=2,5-diphenyl-1,3-oxathiol-2-yl, R═CH₃; -   A=4-nitrophenyl, B=4,6-bis(dimethylamino)-1,3,5-triazin-2-yl, R═CH₃; -   A=phenyl, B=furan-2-yl, R═CH₃; -   A=phenyl, B=1,3-dithian-2-yl, R═CH₃; -   A=phenyl, B=4-chlorothien-2-yl, R═H; -   A=phenyl, B=5-bromothien-2-yl, R═H; -   A=phenyl, B=5-methylthien-2-yl, R═H; -   A=phenyl, B=6-phenylpyrazin-2-yl, R═CH₃; -   A=phenyl, B=3,4-dihydro-3-methyl-2-oxo-2H-1,3-benzo-oxazin-4-yl,     R═CH₃; -   A=phenyl, B=benzothiazol-2-yl, R═CH₃; -   A=2-hydroxy-4-methoxyphenyl, B=2-phenylthiazol-4-yl, R═CH₃; -   A=phenyl, B=5-methylfuran-2-yl, R═CH₃; -   A=phenyl, B=3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl, R═CH₃; -   A=phenyl, B=tetrahydrofuran-2-yl, R═CH₃; -   A=phenyl, B=2,3-dihydro-3-hydroxy-2-oxo-1H-indol-3-yl, R═CH₃, -   A=phenyl, B=4-chloro-1-methyl-2,5-dioxo-2,5-dihydro-pyrrol-3-yl,     R═CH₃; -   A=phenyl, B=2-trifluoroacetyl-1,2,3,4-tetrahydroisoquinolin-1-yl,     R═C₂H₅; -   A=phenyl, B=2-acetyl-1,2,3,4-tetrahydroisoquinolin-1-yl, R═CH₃; -   A=4-nitrophenyl, B=2-(4-nitrophenyl)-3,5,6-triphenyl-pyridin-4-yl,     R═CH₃; -   A=phenyl, B=4,6-bis(dimethylamino)-1,3,5-triazin-2-yl, R═CH₃; -   A=phenyl, B=4-methoxy-5-tert-butoxycarbonyl-1H-pyrro-2-yl, R═CH₃; -   A=phenyl, B=1,3-dihydro-3-oxo-isobenzofuran-1-yl, R═CH₃; -   A=phenyl, B=(5-methoxycarbonylmethyl)thien-2-yl, R═H; -   A=phenyl, B=4-methylthien-2-yl, R═H; -   A=phenyl, B=1,4-dihydro-1-methyl-3-nitroquinolin-4-yl, R═H; -   A=phenyl, B=thien-2-yl, R═H; -   A=phenyl, B=6-methylbenzothiazol-2-yl, R═CH₃; -   A=2-methoxycarbonylphenyl, B=phenyl, R═CH₃; -   A=2-benzyloxy-4-methoxyphenyl, B=2,3,4-trimethoxyphenyl, R═H; -   A=4,5-dimethoxy-2-nitrophenyl, B=3,4-dimethoxyphenyl, R═H; -   A=2-nitrophenyl, B=phenyl, R═H; -   A=2,4,5-trimethoxyphenyl, B=4-methoxyphenyl, R═H; -   A=4-bromophenyl, B=phenyl, R═H; -   A=4-bromophenyl, B=2,4-dinitrophenyl, R═CH₃; -   A=4-chlorophenyl, B=phenyl, R═H; -   A=2,4-dibenzyloxy-5-methoxyphenyl, B=1,3-benzodioxol-5-yl, R═H; -   A=2,4-dibenzyloxyphenyl, B=1,3-benzodioxol-5-yl, R═H; -   A=4-methoxyphenyl, B=2-carboxyphenyl, R═H; -   A=4-methylphenyl, B-2,4-dinitrophenyl, R═CH₃; -   A=4-hydroxy-3-methoxyphenyl, B=4-hydroxy-3-methoxyphenyl, R═H; -   A=2-nitrophenyl, B=4-methylphenyl, R═H; -   A=4-chlorophenyl, B=4-chlorophenyl, R═H; -   A=2,4-diacetoxyphenyl, B=phenyl, R═CH₃; -   A=3-methoxyphenyl, B=phenyl, R═C₂R₅; -   A=4-nitrophenyl, B=phenyl, R═H; -   A=2-nitrophenyl, B=4-n-butoxyphenyl, R═H; -   A=2-nitro-4-chlorophenyl, B=4-methylphenyl, R═H; -   A=phenyl, B=8-carboxynaphthalenyl, R═CH₃; -   A=2,5-dimethoxyphenyl, B=2-hydroxyphenyl, R═C₂R₅; -   A=4-fluorophenyl, B=2-nitro-4-trifluoromethylphenyl, R═CH₃; -   A=3-chloro-4-methylphenyl, B=2,4-dinitrophenyl, R═CH₃; -   A=2-nitro-4-chlorophenyl, B=phenyl, R═H; -   A=4,5-dimethoxy-2-nitrophenyl, B=4-methylphenyl, R═H; -   A=2-carboxy-6-nitrophenyl, B=phenyl, R═CH₃; -   A=2,4,5-trimethoxyphenyl, B=3-methoxyphenyl, R═H; -   A=phenyl, B=4-bromophenyl, R═H; -   A=6-benzyloxy-2,3,4-trimethoxyphenyl, B=1,3-benzodioxol-5-yl, R═H; -   A=4,5-dimethoxy-2-nitrophenyl, B=4-methoxyphenyl, R═H; -   A=4,5-dimethoxy-2-nitrophenyl, B=4-chlorophenyl, R═H; -   A=2,4-dibenzyloxyphenyl, B=4-methoxyphenyl, R═H; -   A=4-methylphenyl, B=4-methylphenyl, R═H; -   A=4-dimethylaminophenyl, B=phenyl, R═H; -   A=4-methoxyphenyl, B=phenyl, R═H; -   A=4,5-dichloro-2-nitrophenyl, B=4-chlorophenyl, R═H; -   A=2-nitrophenyl, B=4-methoxyphenyl, R═H; -   A=phenyl, B=2,5-dimethoxycarbonylaminophenyl, R═CH₃; -   A=4-hydroxy-4-methoxyphenyl, B=2-methoxyphenyl, R═H; -   A=phenyl, B=4-methylphenyl, R═H; -   A=2-nitrophenyl, B=4-ethoxyphenyl, R═H; -   A=2-nitro-4-chlorophenyl, B=4-methoxyphenyl, R═H; -   A=4-chlorophenyl, B-phenyl, R═C₂H₅; -   A=2-t-butoxycarbonyl-5-ethyl-4-methoxyphenyl,     B=2,3-dihydro-7-methyl-1,4-benzodioxin-6-yl, R=t-butyl; -   A=phenyl, B=2-nitro-4-trifluoromethylphenyl, R═CH₃; -   A=3,4-dichlorophenyl, B=2,4-dinitrophenyl, R═CH₃; -   A=4,5-dichloro-2-nitrophenyl, B=4-methoxyphenyl, R═H; -   A=4-methoxy-2-nitrophenyl, B=4-methylphenyl, R═H; -   A=phenyl, B=anthracene-9-yl, R═CH₃; -   A=phenyl, B=4-methoxyphenyl, R═H; -   A=2,4,5-trimethoxyphenyl, B=phenyl, R═H; -   A=2,4-diacetoxyphenyl, B=2,4,5-trimethoxyphenyl, R═CH₃; -   A=2-hydroxyphenyl, B=phenyl, R═H; -   A=4-methoxy-2-nitrophenyl, B=phenyl, R═H; -   A=4,5-dimethoxy-2-nitrophenyl, B=phenyl, R═H; -   A=2,4-dinitrophenyl, B=phenyl, R═CH₃; -   A=phenyl, B=phenyl, R═CH₃; -   A=phenyl, B=4-dimethylaminophenyl, R═H; -   A=phenyl, B=2,4-dinitrophenyl, R═CH₃; -   A=4,5-dichloro-2-nitrophenyl, B=4-methylphenyl, R═H; -   A=4-bromophenyl, B=phenyl, R═CH₃; -   A=2-(4-methylphenylsulfonyloxy)-6-methoxyphenyl, B=phenyl, R═H; -   A=4-methylsulfonylphenyl, B=2-methoxyphenyl, R═CH₃; -   A=4-methoxyphenyl, B=4-methoxyphenyl, R═CH₃; -   A=phenyl, B=4-chlorophenyl, R═H; -   A=2-nitrophenyl, B=4-nitrophenyl, R═H; -   A=phenyl, B=phenyl, R═H; -   A=2,4-dimethoxyphenyl, B=4-methoxyphenyl, R═H; -   A=2-nitrophenyl, B=4-n-hexyloxyphenyl, R═H; -   A=4-methoxy-2-nitrophenyl, B=4-methoxyphenyl, R═H; -   A=phenyl, B=9-carboxyphenanthren-10-yl, R═CH₃; -   A=phenyl, B=phenyl, R═CH₃; -   A=3,4-dimethoxyphenyl, B=3,4-dimethoxyphenyl, R═H; -   A=2,4-dimethoxyphenyl, B=phenyl, R═H; -   A=phenyl, B=2-hydroxy-3,4,6-trimethyl-5-methoxyphenyl, R═CH₃; -   A=4-chloro-2-nitrophenyl, B=4-chlorophenyl, R═H; -   A=2-nitrophenyl, B=4-chlorophenyl, R═H; -   A=2,4,5-trimethoxyphenyl, B=3,4-dimethoxyphenyl, R═H; -   A=4-chlorophenyl, B=2,4-dinitrophenyl, R═CH₃; -   A=4,5-dichloro-2-nitrophenyl, B=phenyl, R═H; -   A=4-methoxyphenyl, B=phenyl, R═CH₃; -   A=2,4-dibenzyloxyphenyl, B=3,4-dimethoxyphenyl, R═H; -   A=4-methylthiophenyl, B-4-methoxyphenyl, R═CH₃; -   A=phenyl, B=phenyl, R═C₂H₅; -   A=4-methoxyphenyl, B=2,4-dinitrophenyl, R═CH₃; -   A=2-nitrophenyl, B=3-chlorophenyl, R═H; -   A=2-nitrophenyl, B=3,4-dimethoxyphenyl, R═H; -   A=4-methoxyphenyl, B=4-methoxyphenyl, R═H; -   A=2-hydroxyphenyl, B=4-methoxyphenyl, R═H; -   A=phenyl, B=2,5-bis(phenacylamino)phenyl, R═CH₃; -   A=4-nitrophenyl, B=4-methylphenyl, R═H; -   A=2-nitrophenyl, B=4-n-pentyloxyphenyl, R═H; -   A=4-methoxy-2-nitrophenyl, B=4-chlorophenyl, R═H; -   A=phenyl, B=2-carboxynaphthalen-1-yl, R═CH₃.

A further object of the present invention relates to the use of derivatives of 1,3-diones having general formula (I)

wherein:

-   A represents: -   an aryl group possibly substituted by one or more substituents     selected from halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆     alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆     alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl,     C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl,     C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆     haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆     haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆     haloalkoxyalkoxyl possibly substituted with a C₁-C₄ alkoxyl or C₁-C₄     haloalkoxyl group, C₂-C₆ alkylthioalkoxyl, C₂-C₆     haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioakyl,     C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆     haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl,     C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈     alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆     haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈     alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂     acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl,     C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈     alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀     alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂     dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, SO₂NR₂R₃,     —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃,     —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂,     -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄,     —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆,     -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₉═CR₄₀R₄₁)(C═Y)T;

or represents a heterocyclic group selected from pyridyl, pyrimidyl, quinolinyl, pyrazolyl, thiazolyl, oxazolyl, thienyl, furyl, benzothienyl, dihydrobenzothienyl, benzofuranyl, dihydrobenzofuranyl, benzoxazolyl, benzoxazolonyl, benzothiazolyl, benzothiazolonyl, benzoimidazolyl, benzoimidazolonyl, benzotriazolyl, chromanonyl, chromanyl, thiochromanonyl, thiochromanyl, 3a,4-dihydro-3H-indeno[1,2-C]isoxazolyl, 3a,4-dihydro-3H-chromeno[4,3-C]isoxazolyl, 5,5-dioxide-3a,4-dihydro-3H-thiochromeno[4,3-C]isoxazolyl, 2,3,3a,4-tetrahydrochromeno[4,3-C]pyrazolyl, 6,6-dioxide-2,3-dihydro-5H-[1,4]dithiino[2,3-C]thiochromenyl, 5,5-dioxide-2,3,3a,4-tetrahydrothiochromeno[4,3-c]pyrazolyl, 1′,1′-dioxide-2′,3′-dihydrospiro[1,3-dioxolane-2,4′-thiochromen]-yl, 1,1,4,4-tetraoxide-2,3-dihydro-1,4-benzodithiin-6-yl 4,4-dioxide-2,3-dihydro-1,4-benzoxathiin-7-yl, 1,1-dioxide-3-oxo-2,3-dihydro-1,2-benzoisothiazol-5-yl, 4-(alkoxyimino)-1,1-dioxide-3,4-dihydro-2H-thiochromen-6-yl, 1,1-dioxide-4-oxo-3,4-dihydro-2H-thiochromen-6-yl, 2,3-dihydro-1,4-benzoxathiin-7-yl,

-   with all these groups possibly substituted by one or more     substituents selected from halogen, NO₂, CN, CHO, OH, linear or     branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or     branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆     cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆     alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl,     C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆     haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆     haloalkoxyalkoxyl, possibly substituted with a C₁-C₄ alkoxyl or     C₁-C₄ haloalkoxyl group, C₂-C₆ alkylthioalkoxyl, C₂-C₆     haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl,     C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆     haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl,     C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈     alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆     haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈     alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂     acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl,     C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈     alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀     alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂     dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃,     —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃,     —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂,     -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄,     —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(p)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(p)Z₁Q₆, -Z     (CR₃₄R₃₅)_(p)(C═Y)T, -Z(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; -   B represents a D-(R_(x))_(n) group; -   R represents a hydrogen atom, a linear or branched C₁-C₆ alkyl     group, a linear or branched C₁-C₆ haloalkyl group, a C₃-C₆     cycloalkyl group or a C₄-C₁₂ cycloalkylalkyl group possibly     substituted with halogen atoms or C₁-C₆ alkyl or C₁-C₆ thioalkyl or     C₁-C₆ alkoxyl or C₂-C₆ alkoxycarbonyl groups, alkenyl C₂-C₆ groups,     alkynyl C₂-C₆ groups, the latter two groups, in turn, possibly     substituted with halogen atoms, a C₅-C₆ cycloalkenyl group possibly     substituted with halogen atoms or C₁-C₆ alkyl groups, an aryl or     arylalkyl group optionally substituted; -   R₁ and R₁₉, represent a C₁-C₆ alkyl or C₁-C₆ haloalkyl group, a     C₃-C₆ cycloalkyl group, an aryl group optionally substituted by one     or more substituents selected from halogen, NO₂, CN, CHO, linear or     branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or     branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆     alkylsulfonyl, C₂-C₆ alkoxycarbonyl; -   m is equal to 0, 1 or 2; -   t is equal to 1 or 2; -   R₂, R₃, R₆, R₇, R₈, R₉, R₁₀, R₁₁, R₁₇ and R₁₈, the same or     different, represent a hydrogen atom, a linear or branched C₁-C₆     alkyl group in turn possibly substituted with halogen atoms, a C₁-C₆     alkoxyl group, a C₃-C₆ cycloalkyl group, an arylalkyl group or an     aryl group, said arylalkyl or aryl groups also optionally     substituted with one or more substituents selected from halogen,     NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched     C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or     branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆     alkoxycarbonyl or, together, represent a C₂-C₅ alkylenic chain; -   R₄, R₅ and R₄₂, represent a hydrogen atom, a linear or branched     C₁-C₆ alkyl group in turn possibly substituted with halogen atoms, a     C₃-C₆ alkenyl group in turn possibly substituted with halogen atoms,     a Q₇ group, an arylalkyl group possibly substituted with one or more     substituents selected from halogen, NO₂, CN, CHO, linear or branched     C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched     C₁-C₆ alkoxyl, linear or branched C₃-C₆ haloalkoxyl, C₁-C₆     alkylsulfonyl, C₂-C₆ alkoxycarbonyl; -   R₁₂, R₁₄ and R₁₆, represent a hydrogen atom, a linear or branched     C₁-C₆ alkyl group in turn possibly substituted with halogen atoms, a     C₃-C₆ cycloalkyl group, a C₁-C₆ alkoxyl group, a C₁-C₆ haloalkoxyl     group; -   R₁₃ and R₁₅, represent a hydrogen atom, a linear or branched C₁-C₆     alkyl group in turn possibly substituted with halogen atoms, a C₃-C₆     alkenyl group, in turn possibly substituted with halogen atoms, a Q₇     group, NH₂, NHCN, NHNH₂, NHOH, an arylalkyl group possibly     substituted with one or more substituents selected from halogen,     NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched     C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or     branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆     alkoxycarbonyl; -   R₂₀, R₂₁, R₂₂, R₂₃, R₂₄, R₂₅, R₂₆, R₂₇, R₂₈ R₂₉, R₃₀, R₃₁, R₃₂, R₃₃,     R₃₄, R₃₅, R₃₆, R₃₇, R₃₈, R₃₉, R₄₀ and R₄₁, the same or different,     represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in     turn possibly substituted with halogen atoms, a C₁-C₆ alkoxyl group,     or the two groups bound to the same carbon atom can be joint by     C₂-C₅ alkylene groups, the alkylene groups can be, in turn,     substituted with C₁-C₃ alkyl groups; -   Q, Q₁, Q₂, Q₃, Q₄, Q₅, Q₆ and Q₇ represent an aryl group, a C₃-C₆     cycloalkyl group, C₅-C₆ cycloalkenyl, a heterocyclic group selected     from triazolyl, triazolonyl, pyrazolyl, imidazolyl,     imidazolydinonyl, tetrazolyl, tetrazolonyl, isoxazolyl, furyl,     thienyl, pyrrolyl, pyrrolidinyl, pyrrolidinonyl, pyridyl,     pyrimidinyl, pyrimidinonyl, pyrazinyl, pyridazinyl, oxazolyl,     thiazolyl, oxadiazolyl, thiadiazolyl, isothiazolyl, benzoxazolyl,     benzothiazolyl, isoxazolinyl, 1,3-dioxanyl, 1,4-dioxanyl,     1,3-dioxolanyl, tetrahydropyranyl, oxethanyl, oxyranyl,     thiazolidinyl, oxazolidinyl, piperidinyl, piperidinonyl,     piperazinyl, morpholinyl, thiazinyl, tetrahydrofuranyl, dioxazolyl,     tetrahydrofuroisoxazolyl, 2-oxa-3-azabicyclo[3.1.0]hex-3-enyl, -   said groups optionally substituted by one or more substituents     selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl,     linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆     alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl,     C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl,     C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆     haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆     haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆     haloalkoxyalkoxyl optionally substituted with a group selected from     C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆     haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl,     C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆     haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl,     C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈     alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆     haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈     alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂     acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl,     C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈     alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀     alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂     dialkylideneiminooxyalkyl, aryl optionally substituted, —S(O)_(m)R₁,     —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉,     —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂,     -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; -   Z, Z₁, Z₂=O, S(O)_(r); -   Y═O, S; -   r is equal to 0, 1 or 2; -   p, q are equal to 1, 2, 3 or 4; -   v is equal to 0 or 1; -   Z₃=O, S or a direct bond; -   T represents a hydrogen atom, a Z₄R₄₂ group, a —NR₄₃R₄₄ group, an     aryl group or a heterocyclic group selected from triazolyl,     triazolonyl, pyrazolyl, imidazolyl, imidazolidinonyl, tetrazolyl,     tetrazolonyl, pyrrolyl, pyrrolidinyl, pyrrolidinonyl, pyridyl,     pyrimidinyl, piperidinyl, piperidinonyl, piperazinyl, morpholinyl,     said groups optionally substituted by one or more substituents     selected from halogen, NO₂, OH, CN, CHO, linear or branched C₁-C₅     alkyl, linear or branched C₁-C₆ haloalkyl, C₃-C₆ cycloalkyl, C₅-C₆     cycloalkenyl, linear or branched C₁-C₆ alkoxyl, linear or branched     C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆     alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl,     C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆     haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, —S(O)_(m)R₁; -   Z₄=O, S or a direct bond; -   R₄₃ and R₄₄, the same or different, represent a hydrogen atom, a     linear or branched C₁-C₆ alkyl group in turn optionally substituted     with halogen atoms, a C₃-C₆ alkenyl group in turn optionally     substituted with halogen atoms, a Q₇ group, an arylalkyl group     optionally substituted by one or more substituents selected from     halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or     branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear     or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆     alkoxycarbonyl, or they jointly represent a C₂-C₅ alkylene chain; -   D represents: -   a heterocyclic group of the heteroaryl or heterocyclic type, in all     the above cases the heterocycle can be mono or polycyclic and can be     connected to the rest of the structure either through one of its     carbon atoms or, when possible, through one of its nitrogen atoms; -   or it represents a mono or polycyclic aryl group, in this latter     case, the group can also be partially saturated; -   R_(x) represents a substituent selected from hydrogen, halogen, NO₂,     CN, CHO, OH, linear or branched C₁-C₆ alkyl, linear or branched     C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or     branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl,     C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆     alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl,     C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆     alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl optionally substituted with     a group selected from C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆     alkylthioalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl,     C₃-C₁₂ dialkylthioalkyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂     dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀     alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆     alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈     haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆     alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈     haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈     alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈     alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈     alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀     alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂     dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃,     —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃,     —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂,     -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄,     —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆,     Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; -   if several R_(x) groups are present, these can be the same or     different; -   n=1-9; -   and of the relevant salts having agronomical compatibility, as     herbicides.

The use of derivatives of 1,3-diones having general formula (I) is a further object of the present invention:

wherein:

-   A, B and R have the above-defined meanings, and of relevant salts     pharmaceutically acceptable as medicament.

Examples of D groups include: pyrrolyl, pyrrolidinonyl, thienyl, furyl, pyrazolyl, imidazolyl, imidazolidinonyl, triazolyl, triazolonyl, tetrazolyl, tetrazolonyl, thiazolyl, isothiazolyl, dithiol, oxathiol, isoxazolyl, isoxazolinyl, oxazolyl, oxadiazolyl, thiadiazolyl, oxatriazolyl, dioxazolyl, oxathiazolyl, pyridyl, N-oxidopyridyl, pyrimidyl, pyrimidinonyl, pyridazinyl, pyrazinyl, triazinyl, tetrazinyl, piperazinyl, oxazinyl, oxathiazinyl, morfolinyl, benzofuranyl, isobenzofuranyl, benzothienyl, isobenzothienyl, indolyl, isoindolyl, benzoxazolyl, benzothiazolyl, benzimidazolyl, benzopyrazolyl, benzotriazolyl, benzoxadiazolyl, benzothiadiazolyl, quinolinyl, quinazolinyl, quinoxalinyl, pyridopyrimidinyl, oxazolepyridinyl, chromenyl, thiochromenyl, purine, phenyl, naphthyl.

A C₁-C₆ alkyl group means a linear or branched C₁-C₆ alkyl group.

Examples of these groups are: methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl.

A C₁-C₆ haloalkyl group means a linear or branched C₁-C₆ alkyl group, substituted with one or more halogen atoms, the same or different.

Examples of this group are: fluoromethyl, chlorodifluoromethyl, difluoromethyl, trifluoromethyl, dichloromethyl, trichloromethyl, 2,2,2-trifluoroethyl, 2,2,2-trichloroethyl, 1,1,2,2,2-pentafluoroethyl, 1,1,2,2-tetrafluoroethyl, 1,2,2,2-tetrafluoroethyl, 2,2,3,3-tetrafluoropropyl, 2,2,3,3,3-pentafluoropropyl.

A C₂-C₆ alkenyl group means a linear or branched C₂-C₆ alkenyl group.

Examples of this group are: ethenyl, propenyl, butenyl.

A C₂-C₆ haloalkenyl group means a linear or branched C₂-C₆ alkenyl group, substituted by one or more halogen atoms, the same or different.

Example of this group are: 3,3-dichloroprop-2-enyl, 3,3-difluoroprop-2-enyl, 3,3,3-trifluoropropenyl.

Example of C₂-C₆ alkynyl groups are: ethynyl, propargyl.

A C₂-C₆ haloalkynyl group means a linear or branched C₂-C₆ alkynyl group, substituted by one or more halogen atoms, the same or different.

Example of this group are: 3-chloropropynyl, 3-iodopropynyl.

Halogen atom means a halogen atom selected from fluorine, chlorine, bromine or iodine.

A C₃-C₆ cycloalkyl group means a cycloalkyl group consisting of 3 to 6 carbon atoms, possibly substituted by one or more substituents the same or different.

Examples of this group are: cyclopropyl, cyclopentyl.

Examples of alkoxy groups are: methoxy, ethoxy.

Examples of haloalkoxyl groups are: difluoromethoxy, trifluoromethoxy, 1,1,2,2-tetrafluoroethoxy, 1,1,2,3,3,3-hexafluoropropoxy.

A heterocyclic group, of the heteroarylic or heterocyclic type, means a ring which can be unsaturated, partially saturated or completely saturated, and can consist of from three to eighteen units containing at least one heteroatom selected from nitrogen, oxygen and sulphur; this group can be condensed with other rings of the heterocyclic or carbocyclic type, which, in turn, can be of the aromatic type, partially saturated or completely saturated.

Mono or polycyclic aryl group means a ring that can be aromatic or partially saturated and consisting exclusively of carbon atoms.

Examples of these groups are: phenyl, naphthyl, tetrahydronaphthalenyl.

The compounds having general formula (I) can exist in different tautomeric and/or isomeric forms, as shown hereinafter:

Both the tautomeric and/or isomeric forms of compounds (I) and the mixtures of the same in any possible proportions, are considered included in the present patent application.

If the particular groups A, B and R allow the existence of other tautomeric and/or isomeric forms, these forms are definitely included within the scope of the present invention.

The salts of compounds (I) which have agronomical compatibility are also considered within the spirit of this patent.

As stated before, the derivatives of 1,3-diones having general formula (I) have a high herbicidal activity.

Specific examples of compounds having general formula (I) of interest for their activity are shown in table 1: (I)

A B R 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-5-yl H 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-5-yl methyl 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-5-yl i-propyl 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-5-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-5-yl CF₃ 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl H 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl methyl 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl i-propyl 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl cyclopropyl 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl CF₃ 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- H oxadiazol-5-yl 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- methyl oxadiazol-5-yl 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- i-propyl oxadiazol-5-yl 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-5-yl 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- CF₃ oxadiazol-5-yl 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-3-yl H 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-3-yl methyl 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-3-yl i-propyl 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2,4-oxadiazol-3-yl CF₃ 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl H 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl methyl 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl i-propyl 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl CF₃ 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- H oxadiazol-3-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- methyl oxadiazol-3-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- i-propyl oxadiazol-3-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-3-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- CF₃ oxadiazol-3-yl 2-NO₂-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl H 2-NO₂-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl methyl 2-NO₂-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl i-propyl 2-NO₂-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl CF₃ 2-NO₂-4-SO₂MePh 1,3,4-oxadiazol-2-yl H 2-NO₂-4-SO₂MePh 1,3,4-oxadiazol-2-yl methyl 2-NO₂-4-SO₂MePh 1,3,4-oxadiazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 1,3,4-oxadiazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,3,4-oxadiazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- H oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- methyl oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- i-propyl oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- cyclopropyl oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- CF₃ oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl H 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl methyl 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,3,4- H oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,3,4- methyl oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,3,4- i-propyl oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,3,4- cyclopropyl oxadiazol-2-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,3,4- CF₃ oxadiazol-2-yl 2-NO₂-4-SO₂MePh 1,2,3-triazol-4-yl H 2-NO₂-4-SO₂MePh 1,2,3-triazol-4-yl methyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-4-yl i-propyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-4-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-4-yl CF₃ 2-NO₂-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl H 2-NO₂-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl methyl 2-NO₂-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl i-propyl 2-NO₂-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl cyclopropyl 2-NO₂-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl CF₃ 2-NO₂-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl H 2-NO₂-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl methyl 2-NO₂-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl i-propyl 2-NO₂-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl cyclopropyl 2-NO₂-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl CF₃ 2-NO₂-4-SO₂MePh 1,2,3-triazol-1-yl H 2-NO₂-4-SO₂MePh 1,2,3-triazol-1-yl methyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-1-yl i-propyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-1-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-1-yl CF₃ 2-NO₂-4-SO₂MePh 1,2,3-triazol-2-yl H 2-NO₂-4-SO₂MePh 1,2,3-triazol-2-yl methyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2,3-triazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 1,2,4-triazol-1-yl H 2-NO₂-4-SO₂MePh 1,2,4-triazol-1-yl methyl 2-NO₂-4-SO₂MePh 1,2,4-triazol-1-yl i-propyl 2-NO₂-4-SO₂MePh 1,2,4-triazol-1-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2,4-triazol-1-yl CF₃ 2-NO₂-4-SO₂MePh imidazol-2-yl H 2-NO₂-4-SO₂MePh imidazol-2-yl methyl 2-NO₂-4-SO₂MePh imidazol-2-yl i-propyl 2-NO₂-4-SO₂MePh imidazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh imidazol-2-yl CF₃ 2-NO₂-4-SO₂MePh imidazol-1-yl H 2-NO₂-4-SO₂MePh imidazol-1-yl methyl 2-NO₂-4-SO₂MePh imidazol-1-yl i-propyl 2-NO₂-4-SO₂MePh imidazol-1-yl cyclopropyl 2-NO₂-4-SO₂MePh imidazol-1-yl CF₃ 2-NO₂-4-SO₂MePh imidazol-4-yl H 2-NO₂-4-SO₂MePh imidazol-4-yl methyl 2-NO₂-4-SO₂MePh imidazol-4-yl i-propyl 2-NO₂-4-SO₂MePh imidazol-4-yl cyclopropyl 2-NO₂-4-SO₂MePh imidazol-4-yl CF₃ 2-NO₂-4-SO₂MePh thiazol-2-yl H 2-NO₂-4-SO₂MePh thiazol-2-yl methyl 2-NO₂-4-SO₂MePh thiazol-2-yl i-propyl 2-NO₂-4-SO₂MePh thiazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh thiazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 4-methylthiazol-2-yl H 2-NO₂-4-SO₂MePh 4-methylthiazol-2-yl methyl 2-NO₂-4-SO₂MePh 4-methylthiazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 4-methylthiazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 4-methylthiazol-2-yl CF₃ 2-NO₂-4-SO₂MePh oxazol-2-yl H 2-NO₂-4-SO₂MePh oxazol-2-yl methyl 2-NO₂-4-SO₂MePh oxazol-2-yl i-propyl 2-NO₂-4-SO₂MePh oxazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh oxazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 4,5-dimethyloxazol-2-yl H 2-NO₂-4-SO₂MePh 4,5-dimethyloxazol-2-yl methyl 2-NO₂-4-SO₂MePh 4,5-dimethyloxazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 4,5-dimethyloxazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 4,5-dimethyloxazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 2-oxazolin-2-yl H 2-NO₂-4-SO₂MePh 2-oxazolin-2-yl methyl 2-NO₂-4-SO₂MePh 2-oxazolin-2-yl i-propyl 2-NO₂-4-SO₂MePh 2-oxazolin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 2-oxazolin-2-yl CF₃ 2-NO₂-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl H 2-NO₂-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl methyl 2-NO₂-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl i-propyl 2-NO₂-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl CF₃ 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-5-yl H 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-5-yl methyl 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-5-yl i-propyl 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-5-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-5-yl CF₃ 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl H 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl methyl 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl i-propyl 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl cyclopropyl 2-NO₂-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl CF₃ 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- H thiadiazol-5-yl 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- methyl thiadiazol-5-yl 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- i-propyl thiadiazol-5-yl 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-5-yl 2-NO₂-4-SO₂MePh 3-trifluoromethyl-1,2,4- CF₃ thiadiazol-5-yl 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-3-yl H 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-3-yl methyl 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-3-yl i-propyl 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2,4-thiadiazol-3-yl CF₃ 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl H 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl methyl 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl i-propyl 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl CF₃ 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- H thiadiazol-3-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- methyl thiadiazol-3-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- i-propyl thiadiazol-3-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-3-yl 2-NO₂-4-SO₂MePh 5-trifluoromethyl-1,2,4- CF₃ thiadiazol-3-yl 2-NO₂-4-SO₂MePh 1,3,4-thiadiazol-2-yl H 2-NO₂-4-SO₂MePh 1,3,4-thiadiazol-2-yl methyl 2-NO₂-4-SO₂MePh 1,3,4-thiadiazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 1,3,4-thiadiazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,3,4-thiadiazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- H thiadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- methyl thiadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- i-propyl thiadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- cyclopropyl thiadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methylsulfonyl-1,3,4- CF₃ thiadiazol-2-yl 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl H 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl methyl 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl CF₃ 2-NO₂-4-SO₂MePh benzoxazol-2-yl H 2-NO₂-4-SO₂MePh benzoxazol-2-yl methyl 2-NO₂-4-SO₂MePh benzoxazol-2-yl i-propyl 2-NO₂-4-SO₂MePh benzoxazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh benzoxazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 6-methylbenzoxazol-2-yl H 2-NO₂-4-SO₂MePh 6-methylbenzoxazol-2-yl methyl 2-NO₂-4-SO₂MePh 6-methylbenzoxazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 6-methylbenzoxazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 6-methylbenzoxazol-2-yl CF₃ 2-NO₂-4-SO₂MePh benzothiazol-2-yl H 2-NO₂-4-SO₂MePh benzothiazol-2-yl methyl 2-NO₂-4-SO₂MePh benzothiazol-2-yl i-propyl 2-NO₂-4-SO₂MePh benzothiazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh benzothiazol-2-yl CF₃ 2-NO₂-4-SO₂MePh pyrazol-1-yl H 2-NO₂-4-SO₂MePh pyrazol-1-yl methyl 2-NO₂-4-SO₂MePh pyrazol-1-yl i-propyl 2-NO₂-4-SO₂MePh pyrazol-1-yl cyclopropyl 2-NO₂-4-SO₂MePh pyrazol-1-yl CF₃ 2-NO₂-4-SO₂MePh pyrazol-3-yl H 2-NO₂-4-SO₂MePh pyrazol-3-yl methyl 2-NO₂-4-SO₂MePh pyrazol-3-yl i-propyl 2-NO₂-4-SO₂MePh pyrazol-3-yl cyclopropyl 2-NO₂-4-SO₂MePh pyrazol-3-yl CF₃ 2-NO₂-4-SO₂MePh 1-methylpyrazol-3-yl H 2-NO₂-4-SO₂MePh 1-methylpyrazol-3-yl methyl 2-NO₂-4-SO₂MePh 1-methylpyrazol-3-yl i-propyl 2-NO₂-4-SO₂MePh 1-methylpyrazol-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 1-methylpyrazol-3-yl CF₃ 2-NO₂-4-SO₂MePh tetrazol-1-yl H 2-NO₂-4-SO₂MePh tetrazol-1-yl methyl 2-NO₂-4-SO₂MePh tetrazol-1-yl i-propyl 2-NO₂-4-SO₂MePh tetrazol-1-yl cyclopropyl 2-NO₂-4-SO₂MePh tetrazol-1-yl CF₃ 2-NO₂-4-SO₂MePh 5-methyltetrazol-1-yl H 2-NO₂-4-SO₂MePh 5-methyltetrazol-1-yl methyl 2-NO₂-4-SO₂MePh 5-methyltetrazol-1-yl i-propyl 2-NO₂-4-SO₂MePh 5-methyltetrazol-1-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-methyltetrazol-1-yl CF₃ 2-NO₂-4-SO₂MePh tetrazol-2-yl H 2-NO₂-4-SO₂MePh tetrazol-2-yl methyl 2-NO₂-4-SO₂MePh tetrazol-2-yl i-propyl 2-NO₂-4-SO₂MePh tetrazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh tetrazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 5-methyltetrazol-2-yl H 2-NO₂-4-SO₂MePh 5-methyltetrazol-2-yl methyl 2-NO₂-4-SO₂MePh 5-methyltetrazol-2-yl i-propyl 2-NO₂-4-SO₂MePh 5-methyltetrazol-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-methyltetrazol-2-yl CF₃ 2-NO₂-4-SO₂MePh 1-methyltetrazol-5-yl H 2-NO₂-4-SO₂MePh 1-methyltetrazol-5-yl methyl 2-NO₂-4-SO₂MePh 1-methyltetrazol-5-yl i-propyl 2-NO₂-4-SO₂MePh 1-methyltetrazol-5-yl cyclopropyl 2-NO₂-4-SO₂MePh 1-methyltetrazol-5-yl CF₃ 2-NO₂-4-SO₂MePh 2-methyltetrazol-5-yl H 2-NO₂-4-SO₂MePh 2-methyltetrazol-5-yl methyl 2-NO₂-4-SO₂MePh 2-methyltetrazol-5-yl i-propyl 2-NO₂-4-SO₂MePh 2-methyltetrazol-5-yl cyclopropyl 2-NO₂-4-SO₂MePh 2-methyltetrazol-5-yl CF₃ 2-NO₂-4-SO₂MePh pyridin-2-yl H 2-NO₂-4-SO₂MePh pyridin-2-yl methyl 2-NO₂-4-SO₂MePh pyridin-2-yl i-propyl 2-NO₂-4-SO₂MePh pyridin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh pyridin-2-yl CF₃ 2-NO₂-4-SO₂MePh pyridin-4-yl H 2-NO₂-4-SO₂MePh pyridin-4-yl methyl 2-NO₂-4-SO₂MePh pyridin-4-yl i-propyl 2-NO₂-4-SO₂MePh pyridin-4-yl cyclopropyl 2-NO₂-4-SO₂MePh pyridin-4-yl CF₃ 2-NO₂-4-SO₂MePh pyridin-3-yl H 2-NO₂-4-SO₂MePh pyridin-3-yl methyl 2-NO₂-4-SO₂MePh pyridin-3-yl i-propyl 2-NO₂-4-SO₂MePh pyridin-3-yl cyclopropyl 2-NO₂-4-SO₂MePh pyridin-3-yl CF₃ 2-NO₂-4-SO₂MePh 3-nitropyridin-4-yl H 2-NO₂-4-SO₂MePh 3-nitropyridin-4-yl methyl 2-NO₂-4-SO₂MePh 3-nitropyridin-4-yl i-propyl 2-NO₂-4-SO₂MePh 3-nitropyridin-4-yl cyclopropyl 2-NO₂-4-SO₂MePh 3-nitropyridin-4-yl CF₃ 2-NO₂-4-SO₂MePh 5-cyanopyridin-2-yl H 2-NO₂-4-SO₂MePh 5-cyanopyridin-2-yl methyl 2-NO₂-4-SO₂MePh 5-cyanopyridin-2-yl i-propyl 2-NO₂-4-SO₂MePh 5-cyanopyridin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-cyanopyridin-2-yl CF₃ 2-NO₂-4-SO₂MePh 5-trifluoromethylpyridin-2-yl H 2-NO₂-4-SO₂MePh 5-trifluoromethylpyridin-2-yl methyl 2-NO₂-4-SO₂MePh 5-trifluoromethylpyridin-2-yl i-propyl 2-NO₂-4-SO₂MePh 5-trifluoromethylpyridin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh 5-trifluoromethylpyridin-2-yl CF₃ 2-NO₂-4-SO₂MePh pyrimidin-2-yl H 2-NO₂-4-SO₂MePh pyrimidin-2-yl methyl 2-NO₂-4-SO₂MePh pyrimidin-2-yl i-propyl 2-NO₂-4-SO₂MePh pyrimidin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh pyrimidin-2-yl CF₃ 2-NO₂-4-SO₂MePh pyrimidin-4-yl H 2-NO₂-4-SO₂MePh pyrimidin-4-yl methyl 2-NO₂-4-SO₂MePh pyrimidin-4-yl i-propyl 2-NO₂-4-SO₂MePh pyrimidin-4-yl cyclopropyl 2-NO₂-4-SO₂MePh pyrimidin-4-yl CF₃ 2-NO₂-4-SO₂MePh 6-chloropyrimidin-4-yl methyl 2-NO₂-4-SO₂MePh 6-chloropyrimidin-4-yl i-propyl 2-NO₂-4-SO₂MePh 6-chloropyrimidin-4-yl cyclopropyl 2-NO₂-4-SO₂MePh 6-chloropyrimidin-4-yl CF₃ 2-NO₂-4-SO₂MePh pyridazin-3-yl H 2-NO₂-4-SO₂MePh pyridazin-3-yl methyl 2-NO₂-4-SO₂MePh pyridazin-3-yl i-propyl 2-NO₂-4-SO₂MePh pyridazin-3-yl cyclopropyl 2-NO₂-4-SO₂MePh pyridazin-3-yl CF₃ 2-NO₂-4-SO₂MePh 6-chloropyridazin-3-yl methyl 2-NO₂-4-SO₂MePh 6-chloropyridazin-3-yl i-propyl 2-NO₂-4-SO₂MePh 6-chloropyridazin-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 6-chloropyridazin-3-yl CF₃ 2-NO₂-4-SO₂MePh pyrazin-2-yl methyl 2-NO₂-4-SO₂MePh pyrazin-2-yl i-propyl 2-NO₂-4-SO₂MePh pyrazin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh pyrazin-2-yl CF₃ 2-NO₂-4-SO₂MePh triazin-2-yl methyl 2-NO₂-4-SO₂MePh triazin-2-yl i-propyl 2-NO₂-4-SO₂MePh triazin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh triazin-2-yl CF₃ 2-NO₂-4-SO₂MePh quinolin-2-yl methyl 2-NO₂-4-SO₂MePh quinolin-2-yl i-propyl 2-NO₂-4-SO₂MePh quinolin-2-yl cyclopropyl 2-NO₂-4-SO₂MePh quinolin-2-yl CF₃ 2-NO₂-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- H 1,3(4H)-oxazin-2-yl 2-NO₂-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- methyl 1,3(4H)-oxazin-2-yl 2-NO₂-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- i-propyl 1,3(4H)-oxazin-2-yl 2-NO₂-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- cyclopropyl 1,3(4H)-oxazin-2-yl 2-NO₂-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- CF₃ 1,3(4H)-oxazin-2-yl 2-NO₂-4-SO₂MePh 2-oxazolidinon-3-yl H 2-NO₂-4-SO₂MePh 2-oxazolidinon-3-yl methyl 2-NO₂-4-SO₂MePh 2-oxazolidinon-3-yl i-propyl 2-NO₂-4-SO₂MePh 2-oxazolidinon-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 2-oxazolidinon-3-yl CF₃ 2-NO₂-4-SO₂MePh 2-pyrrolidinon-1-yl methyl 2-NO₂-4-SO₂MePh 2-pyrrolidinon-1-yl i-propyl 2-NO₂-4-SO₂MePh 2-pyrrolidinon-1-yl cyclopropyl 2-NO₂-4-SO₂MePh 2-pyrrolidinon-1-yl CF₃ 2-NO₂-4-SO₂MePh 3-methylisoxazol-5-yl methyl 2-NO₂-4-SO₂MePh 3-methylisoxazol-5-yl i-propyl 2-NO₂-4-SO₂MePh 3-methylisoxazol-5-yl cyclopropyl 2-NO₂-4-SO₂MePh 3-methylisoxazol-5-yl CF₃ 2-NO₂-4-SO₂MePh 2-NO₂-4-SO₂MePh H 2-NO₂-4-SO₂MePh 2-NO₂-4-SO₂MePh methyl 2-NO₂-4-SO₂MePh 2-NO₂-4-SO₂MePh i-propyl 2-NO₂-4-SO₂MePh 2-NO₂-4-SO₂MePh cyclopropyl 2-NO₂-4-SO₂MePh 2-NO₂-4-SO₂MePh CF₃ 2-NO₂-4-SO₂MePh 2-Cl-4-SO₂MePh H 2-NO₂-4-SO₂MePh 2-Cl-4-SO₂MePh methyl 2-NO₂-4-SO₂MePh 2-Cl-4-SO₂MePh i-propyl 2-NO₂-4-SO₂MePh 2-Cl-4-SO₂MePh cyclopropyl 2-NO₂-4-SO₂MePh 2-Cl-4-SO₂MePh CF₃ 2-NO₂-4-SO₂MePh 2-NO₂-4-CF₃Ph H 2-NO₂-4-SO₂MePh 2-NO₂-4-CF₃Ph methyl 2-NO₂-4-SO₂MePh 2-NO₂-4-CF₃Ph i-propyl 2-NO₂-4-SO₂MePh 2-NO₂-4-CF₃Ph cyclopropyl 2-NO₂-4-SO₂MePh 2-NO₂-4-CF₃Ph CF₃ 2-NO₂-4-SO₂MePh 2-NO₂-4-ClPh H 2-NO₂-4-SO₂MePh 2-NO₂-4-ClPh methyl 2-NO₂-4-SO₂MePh 2-NO₂-4-ClPh i-propyl 2-NO₂-4-SO₂MePh 2-NO₂-4-ClPh cyclopropyl 2-NO₂-4-SO₂MePh 2-NO₂-4-ClPh CF₃ 2-NO₂-4-SO₂MePh 2-Cl-4-NO₂Ph H 2-NO₂-4-SO₂MePh 2-Cl-4-NO₂Ph methyl 2-NO₂-4-SO₂MePh 2-Cl-4-NO₂Ph i-propyl 2-NO₂-4-SO₂MePh 2-Cl-4-NO₂Ph cyclopropyl 2-NO₂-4-SO₂MePh 2-Cl-4-NO₂Ph CF₃ 2-NO₂-4-SO₂MePh 2,4-(NO₂)₂Ph H 2-NO₂-4-SO₂MePh 2,4-(NO₂)₂Ph methyl 2-NO₂-4-SO₂MePh 2,4-(NO₂)₂Ph i-propyl 2-NO₂-4-SO₂MePh 2,4-(NO₂)₂Ph cyclopropyl 2-NO₂-4-SO₂MePh 2,4-(NO₂)₂Ph CF₃ 2-NO₂-4-SO₂MePh 4-F-3-NO₂Ph H 2-NO₂-4-SO₂MePh 4-F-3-NO₂Ph methyl 2-NO₂-4-SO₂MePh 4-F-3-NO₂Ph i-propyl 2-NO₂-4-SO₂MePh 4-F-3-NO₂Ph cyclopropyl 2-NO₂-4-SO₂MePh 4-F-3-NO₂Ph CF₃ 2-NO₂-4-SO₂MePh 3,5-(CF₃)₂Ph H 2-NO₂-4-SO₂MePh 3,5-(CF₃)₂Ph methyl 2-NO₂-4-SO₂MePh 3,5-(CF₃)₂Ph i-propyl 2-NO₂-4-SO₂MePh 3,5-(CF₃)₂Ph cyclopropyl 2-NO₂-4-SO₂MePh 3,5-(CF₃)₂Ph CF₃ 2-NO₂-4-SO₂MePh 2-SO₂Me-4-CF₃Ph H 2-NO₂-4-SO₂MePh 2-SO₂Me-4-CF₃Ph methyl 2-NO₂-4-SO₂MePh 2-SO₂Me-4-CF₃Ph i-propyl 2-NO₂-4-SO₂MePh 2-SO₂Me-4-CF₃Ph cyclopropyl 2-NO₂-4-SO₂MePh 2-SO₂Me-4-CF₃Ph CF₃ 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5-yl H 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5-yl methyl 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5-yl i-propyl 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5-yl CF₃ 2-Cl-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl H 2-Cl-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl methyl 2-Cl-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl i-propyl 2-Cl-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl cyclopropyl 2-Cl-4-SO₂MePh 3-methyl-1,2,4-oxadiazol-5-yl CF₃ 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- H oxadiazol-5-yl 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- methyl oxadiazol-5-yl 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- i-propyl oxadiazol-5-yl 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-5-yl 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- CF₃ oxadiazol-5-yl 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3-yl H 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3-yl methyl 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3-yl i-propyl 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3-yl CF₃ 2-Cl-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl H 2-Cl-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl methyl 2-Cl-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl i-propyl 2-Cl-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl cyclopropyl 2-Cl-4-SO₂MePh 5-methyl-1,2,4-oxadiazol-3-yl CF₃ 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- H oxadiazol-3-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- methyl oxadiazol-3-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- i-propyl oxadiazol-3-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-3-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- CF₃ oxadiazol-3-yl 2-Cl-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl H 2-Cl-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl methyl 2-Cl-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl i-propyl 2-Cl-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl cyclopropyl 2-Cl-4-SO₂MePh 5-chloro-1,2,4-oxadiazol-3-yl CF₃ 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2-yl H 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2-yl methyl 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2-yl i-propyl 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2-yl CF₃ 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- H oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- methyl oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- i-propyl oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- cyclopropyl oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- CF₃ oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl H 2-Cl-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl methyl 2-Cl-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl i-propyl 2-Cl-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 5-methyl-1,3,4-oxadiazol-2-yl CF₃ 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,3,4- H oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,3,4- methyl oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,3,4- i-propyl oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,3,4- cyclopropyl oxadiazol-2-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,3,4- CF₃ oxadiazol-2-yl 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl H 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl methyl 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl i-propyl 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl CF₃ 2-Cl-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl H 2-Cl-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl methyl 2-Cl-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl i-propyl 2-Cl-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl cyclopropyl 2-Cl-4-SO₂MePh 1-methyl-1,2,3-triazol-4-yl CF₃ 2-Cl-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl H 2-Cl-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl methyl 2-Cl-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl i-propyl 2-Cl-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl cyclopropyl 2-Cl-4-SO₂MePh 2-methyl-1,2,3-triazol-4-yl CF₃ 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl H 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl methyl 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl i-propyl 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl CF₃ 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl H 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl methyl 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl i-propyl 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl CF₃ 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl H 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl methyl 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl i-propyl 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl CF₃ 2-Cl-4-SO₂MePh imidazol-2-yl H 2-Cl-4-SO₂MePh imidazol-2-yl methyl 2-Cl-4-SO₂MePh imidazol-2-yl i-propyl 2-Cl-4-SO₂MePh imidazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh imidazol-2-yl CF₃ 2-Cl-4-SO₂MePh imidazol-1-yl H 2-Cl-4-SO₂MePh imidazol-1-yl methyl 2-Cl-4-SO₂MePh imidazol-1-yl i-propyl 2-Cl-4-SO₂MePh imidazol-1-yl cyclopropyl 2-Cl-4-SO₂MePh imidazol-1-yl CF₃ 2-Cl-4-SO₂MePh imidazol-4-yl H 2-Cl-4-SO₂MePh imidazol-4-yl methyl 2-Cl-4-SO₂MePh imidazol-4-yl i-propyl 2-Cl-4-SO₂MePh imidazol-4-yl cyclopropyl 2-Cl-4-SO₂MePh imidazol-4-yl CF₃ 2-Cl-4-SO₂MePh thiazol-2-yl H 2-Cl-4-SO₂MePh thiazol-2-yl methyl 2-Cl-4-SO₂MePh thiazol-2-yl i-propyl 2-Cl-4-SO₂MePh thiazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh thiazol-2-yl CF₃ 2-Cl-4-SO₂MePh 4-methylthiazol-2-yl H 2-Cl-4-SO₂MePh 4-methylthiazol-2-yl methyl 2-Cl-4-SO₂MePh 4-methylthiazol-2-yl i-propyl 2-Cl-4-SO₂MePh 4-methylthiazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 4-methylthiazol-2-yl CF₃ 2-Cl-4-SO₂MePh oxazol-2-yl H 2-Cl-4-SO₂MePh oxazol-2-yl methyl 2-Cl-4-SO₂MePh oxazol-2-yl i-propyl 2-Cl-4-SO₂MePh oxazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh oxazol-2-yl CF₃ 2-Cl-4-SO₂MePh 4,5-dimethyloxazol-2-yl H 2-Cl-4-SO₂MePh 4,5-dimethyloxazol-2-yl methyl 2-Cl-4-SO₂MePh 4,5-dimethyloxazol-2-yl i-propyl 2-Cl-4-SO₂MePh 4,5-dimethyloxazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 4,5-dimethyloxazol-2-yl CF₃ 2-Cl-4-SO₂MePh 2-oxazolin-2-yl H 2-Cl-4-SO₂MePh 2-oxazolin-2-yl methyl 2-Cl-4-SO₂MePh 2-oxazolin-2-yl i-propyl 2-Cl-4-SO₂MePh 2-oxazolin-2-yl cyclopropyl 2-Cl-4-SO₂MePh 2-oxazolin-2-yl CF₃ 2-Cl-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl H 2-Cl-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl methyl 2-Cl-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl i-propyl 2-Cl-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl cyclopropyl 2-Cl-4-SO₂MePh 4,4-dimethyl-2-oxazolin-2-yl CF₃ 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-5-yl H 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-5-yl methyl 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-5-yl i-propyl 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-5-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-5-yl CF₃ 2-Cl-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl H 2-Cl-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl methyl 2-Cl-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl i-propyl 2-Cl-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl cyclopropyl 2-Cl-4-SO₂MePh 3-methyl-1,2,4-thiadiazol-5-yl CF₃ 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- H thiadiazol-5-yl 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- methyl thiadiazol-5-yl 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- i-propyl thiadiazol-5-yl 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-5-yl 2-Cl-4-SO₂MePh 3-trifluoromethyl-1,2,4- CF₃ thiadiazol-5-yl 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-3-yl H 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-3-yl methyl 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-3-yl i-propyl 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-3-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2,4-thiadiazol-3-yl CF₃ 2-Cl-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl H 2-Cl-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl methyl 2-Cl-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl i-propyl 2-Cl-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl cyclopropyl 2-Cl-4-SO₂MePh 5-methyl-1,2,4-thiadiazol-3-yl CF₃ 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- H thiadiazol-3-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- methyl thiadiazol-3-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- i-propyl thiadiazol-3-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-3-yl 2-Cl-4-SO₂MePh 5-trifluoromethyl-1,2,4- CF₃ thiadiazol-3-yl 2-Cl-4-SO₂MePh 1,3,4-thiadiazol-2-yl H 2-Cl-4-SO₂MePh 1,3,4-thiadiazol-2-yl methyl 2-Cl-4-SO₂MePh 1,3,4-thiadiazol-2-yl i-propyl 2-Cl-4-SO₂MePh 1,3,4-thiadiazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 1,3,4-thiadiazol-2-yl CF₃ 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- H thiadiazol-2-yl 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- methyl thiadiazol-2-yl 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- i-propyl thiadiazol-2-yl 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- cyclopropyl thiadiazol-2-yl 2-Cl-4-SO₂MePh 5-methylsulfonyl-1,3,4- CF₃ thiadiazol-2-yl 2-Cl-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl H 2-Cl-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl methyl 2-Cl-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl i-propyl 2-Cl-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 5-methyl-1,3,4-thiadiazol-2-yl CF₃ 2-Cl-4-SO₂MePh benzoxazol-2-yl H 2-Cl-4-SO₂MePh benzoxazol-2-yl methyl 2-Cl-4-SO₂MePh benzoxazol-2-yl i-propyl 2-Cl-4-SO₂MePh benzoxazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh benzoxazol-2-yl CF₃ 2-Cl-4-SO₂MePh 6-methylbenzoxazol-2-yl H 2-Cl-4-SO₂MePh 6-methylbenzoxazol-2-yl methyl 2-Cl-4-SO₂MePh 6-methylbenzoxazol-2-yl i-propyl 2-Cl-4-SO₂MePh 6-methylbenzoxazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 6-methylbenzoxazol-2-yl CF₃ 2-Cl-4-SO₂MePh benzothiazol-2-yl H 2-Cl-4-SO₂MePh benzothiazol-2-yl methyl 2-Cl-4-SO₂MePh benzothiazol-2-yl i-propyl 2-Cl-4-SO₂MePh benzothiazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh benzothiazol-2-yl CF₃ 2-Cl-4-SO₂MePh pyrazol-1-yl H 2-Cl-4-SO₂MePh pyrazol-1-yl methyl 2-Cl-4-SO₂MePh pyrazol-1-yl i-propyl 2-Cl-4-SO₂MePh pyrazol-1-yl cyclopropyl 2-Cl-4-SO₂MePh pyrazol-1-yl CF₃ 2-Cl-4-SO₂MePh pyrazol-3-yl H 2-Cl-4-SO₂MePh pyrazol-3-yl methyl 2-Cl-4-SO₂MePh pyrazol-3-yl i-propyl 2-Cl-4-SO₂MePh pyrazol-3-yl cyclopropyl 2-Cl-4-SO₂MePh pyrazol-3-yl CF₃ 2-Cl-4-SO₂MePh 1-methylpyrazol-3-yl H 2-Cl-4-SO₂MePh 1-methylpyrazol-3-yl methyl 2-Cl-4-SO₂MePh 1-methylpyrazol-3-yl i-propyl 2-Cl-4-SO₂MePh 1-methylpyrazol-3-yl cyclopropyl 2-Cl-4-SO₂MePh 1-methylpyrazol-3-yl CF₃ 2-Cl-4-SO₂MePh tetrazol-1-yl H 2-Cl-4-SO₂MePh tetrazol-1-yl methyl 2-Cl-4-SO₂MePh tetrazol-1-yl i-propyl 2-Cl-4-SO₂MePh tetrazol-1-yl cyclopropyl 2-Cl-4-SO₂MePh tetrazol-1-yl CF₃ 2-Cl-4-SO₂MePh 5-methyltetrazol-1-yl H 2-Cl-4-SO₂MePh 5-methyltetrazol-1-yl methyl 2-Cl-4-SO₂MePh 5-methyltetrazol-1-yl i-propyl 2-Cl-4-SO₂MePh 5-methyltetrazol-1-yl cyclopropyl 2-Cl-4-SO₂MePh 5-methyltetrazol-1-yl CF₃ 2-Cl-4-SO₂MePh tetrazol-2-yl H 2-Cl-4-SO₂MePh tetrazol-2-yl methyl 2-Cl-4-SO₂MePh tetrazol-2-yl i-propyl 2-Cl-4-SO₂MePh tetrazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh tetrazol-2-yl CF₃ 2-Cl-4-SO₂MePh 5-methyltetrazol-2-yl H 2-Cl-4-SO₂MePh 5-methyltetrazol-2-yl methyl 2-Cl-4-SO₂MePh 5-methyltetrazol-2-yl i-propyl 2-Cl-4-SO₂MePh 5-methyltetrazol-2-yl cyclopropyl 2-Cl-4-SO₂MePh 5-methyltetrazol-2-yl CF₃ 2-Cl-4-SO₂MePh 1-methyltetrazol-5-yl H 2-Cl-4-SO₂MePh 1-methyltetrazol-5-yl methyl 2-Cl-4-SO₂MePh 1-methyltetrazol-5-yl i-propyl 2-Cl-4-SO₂MePh 1-methyltetrazol-5-yl cyclopropyl 2-Cl-4-SO₂MePh 1-methyltetrazol-5-yl CF₃ 2-Cl-4-SO₂MePh 2-methyltetrazol-5-yl H 2-Cl-4-SO₂MePh 2-methyltetrazol-5-yl methyl 2-Cl-4-SO₂MePh 2-methyltetrazol-5-yl i-propyl 2-Cl-4-SO₂MePh 2-methyltetrazol-5-yl cyclopropyl 2-Cl-4-SO₂MePh 2-methyltetrazol-5-yl CF₃ 2-Cl-4-SO₂MePh pyridin-2-yl H 2-Cl-4-SO₂MePh pyridin-2-yl methyl 2-Cl-4-SO₂MePh pyridin-2-yl i-propyl 2-Cl-4-SO₂MePh pyridin-2-yl cyclopropyl 2-Cl-4-SO₂MePh pyridin-2-yl CF₃ 2-Cl-4-SO₂MePh pyridin-4-yl H 2-Cl-4-SO₂MePh pyridin-4-yl methyl 2-Cl-4-SO₂MePh pyridin-4-yl i-propyl 2-Cl-4-SO₂MePh pyridin-4-yl cyclopropyl 2-Cl-4-SO₂MePh pyridin-4-yl CF₃ 2-Cl-4-SO₂MePh pyridin-3-yl H 2-Cl-4-SO₂MePh pyridin-3-yl methyl 2-Cl-4-SO₂MePh pyridin-3-yl i-propyl 2-Cl-4-SO₂MePh pyridin-3-yl cyclopropyl 2-Cl-4-SO₂MePh pyridin-3-yl CF₃ 2-Cl-4-SO₂MePh 3-nitropyridin-4-yl H 2-Cl-4-SO₂MePh 3-nitropyridin-4-yl methyl 2-Cl-4-SO₂MePh 3-nitropyridin-4-yl i-propyl 2-Cl-4-SO₂MePh 3-nitropyridin-4-yl cyclopropyl 2-Cl-4-SO₂MePh 3-nitropyridin-4-yl CF₃ 2-Cl-4-SO₂MePh 5-cyanopyridin-2-yl H 2-Cl-4-SO₂MePh 5-cyanopyridin-2-yl methyl 2-Cl-4-SO₂MePh 5-cyanopyridin-2-yl i-propyl 2-Cl-4-SO₂MePh 5-cyanopyridin-2-yl cyclopropyl 2-Cl-4-SO₂MePh 5-cyanopyridin-2-yl CF₃ 2-Cl-4-SO₂MePh 5-trifluoromethylpyridin-2-yl H 2-Cl-4-SO₂MePh 5-trifluoromethylpyridin-2-yl methyl 2-Cl-4-SO₂MePh 5-trifluoromethylpyridin-2-yl i-propyl 2-Cl-4-SO₂MePh 5-trifluoromethylpyridin-2-yl cyclopropyl 2-Cl-4-SO₂MePh 5-trifluoromethylpyridin-2-yl CF₃ 2-Cl-4-SO₂MePh pyrimidin-2-yl H 2-Cl-4-SO₂MePh pyrimidin-2-yl methyl 2-Cl-4-SO₂MePh pyrimidin-2-yl i-propyl 2-Cl-4-SO₂MePh pyrimidin-2-yl cyclopropyl 2-Cl-4-SO₂MePh pyrimidin-2-yl CF₃ 2-Cl-4-SO₂MePh pyrimidin-4-yl H 2-Cl-4-SO₂MePh pyrimidin-4-yl methyl 2-Cl-4-SO₂MePh pyrimidin-4-yl i-propyl 2-Cl-4-SO₂MePh pyrimidin-4-yl cyclopropyl 2-Cl-4-SO₂MePh pyrimidin-4-yl CF₃ 2-Cl-4-SO₂MePh 6-chloropyrimidin-4-yl methyl 2-Cl-4-SO₂MePh 6-chloropyrimidin-4-yl i-propyl 2-Cl-4-SO₂MePh 6-chloropyrimidin-4-yl cyclopropyl 2-Cl-4-SO₂MePh 6-chloropyrimidin-4-yl CF₃ 2-Cl-4-SO₂MePh pyridazin-3-yl H 2-Cl-4-SO₂MePh pyridazin-3-yl methyl 2-Cl-4-SO₂MePh pyridazin-3-yl i-propyl 2-Cl-4-SO₂MePh pyridazin-3-yl cyclopropyl 2-Cl-4-SO₂MePh pyridazin-3-yl CF₃ 2-Cl-4-SO₂MePh 6-chloropyridazin-3-yl methyl 2-Cl-4-SO₂MePh 6-chloropyridazin-3-yl i-propyl 2-Cl-4-SO₂MePh 6-chloropyridazin-3-yl cyclopropyl 2-Cl-4-SO₂MePh 6-chloropyridazin-3-yl CF₃ 2-Cl-4-SO₂MePh pyrazin-2-yl methyl 2-Cl-4-SO₂MePh pyrazin-2-yl i-propyl 2-Cl-4-SO₂MePh pyrazin-2-yl cyclopropyl 2-Cl-4-SO₂MePh pyrazin-2-yl CF₃ 2-Cl-4-SO₂MePh triazin-2-yl methyl 2-Cl-4-SO₂MePh triazin-2-yl i-propyl 2-Cl-4-SO₂MePh triazin-2-yl cyclopropyl 2-Cl-4-SO₂MePh triazin-2-yl CF₃ 2-Cl-4-SO₂MePh quinolin-2-yl methyl 2-Cl-4-SO₂MePh quinolin-2-yl i-propyl 2-Cl-4-SO₂MePh quinolin-2-yl cyclopropyl 2-Cl-4-SO₂MePh quinolin-2-yl CF₃ 2-Cl-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- H 1,3(4H)-oxazin-2-yl 2-Cl-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- methyl 1,3(4H)-oxazin-2-yl 2-Cl-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- i-propyl 1,3(4H)-oxazin-2-yl 2-Cl-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- cyclopropyl 1,3(4H)-oxazin-2-yl 2-Cl-4-SO₂MePh 4,4,6-trimethyl-5,6-dihydro- CF₃ 1,3(4H)-oxazin-2-yl 2-Cl-4-SO₂MePh 2-oxazolidinon-3-yl H 2-Cl-4-SO₂MePh 2-oxazolidinon-3-yl methyl 2-Cl-4-SO₂MePh 2-oxazolidinon-3-yl i-propyl 2-Cl-4-SO₂MePh 2-oxazolidinon-3-yl cyclopropyl 2-Cl-4-SO₂MePh 2-oxazolidinon-3-yl CF₃ 2-Cl-4-SO₂MePh 2-pyrrolidinon-1-yl methyl 2-Cl-4-SO₂MePh 2-pyrrolidinon-1-yl i-propyl 2-Cl-4-SO₂MePh 2-pyrrolidinon-1-yl cyclopropyl 2-Cl-4-SO₂MePh 2-pyrrolidinon-1-yl CF₃ 2-Cl-4-SO₂MePh 3-methylisoxazol-5-yl methyl 2-Cl-4-SO₂MePh 3-methylisoxazol-5-yl i-propyl 2-Cl-4-SO₂MePh 3-methylisoxazol-5-yl cyclopropyl 2-Cl-4-SO₂MePh 3-methylisoxazol-5-yl CF₃ 2-Cl-4-SO₂MePh 2-NO₂-4-SO₂MePh H 2-Cl-4-SO₂MePh 2-NO₂-4-SO₂MePh methyl 2-Cl-4-SO₂MePh 2-NO₂-4-SO₂MePh i-propyl 2-Cl-4-SO₂MePh 2-NO₂-4-SO₂MePh cyclopropyl 2-Cl-4-SO₂MePh 2-NO₂-4-SO₂MePh CF₃ 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh H 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh methyl 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh i-propyl 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh cyclopropyl 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh CF₃ 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph H 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph methyl 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph i-propyl 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph cyclopropyl 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph CF₃ 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh H 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh methyl 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh i-propyl 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh cyclopropyl 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh CF₃ 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph H 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph methyl 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph i-propyl 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph cyclopropyl 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph CF₃ 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph H 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph methyl 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph i-propyl 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph cyclopropyl 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph CF₃ 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph H 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph methyl 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph i-propyl 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph cyclopropyl 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph CF₃ 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph H 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph methyl 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph i-propyl 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph cyclopropyl 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph CF₃ 2-Cl-4-SO₂MePh 2-SO₂Me-4-CF₃Ph H 2-Cl-4-SO₂MePh 2-SO₂Me-4-CF₃Ph methyl 2-Cl-4-SO₂MePh 2-SO₂Me-4-CF₃Ph i-propyl 2-Cl-4-SO₂MePh 2-SO₂Me-4-CF₃Ph cyclopropyl 2-Cl-4-SO₂MePh 2-SO₂Me-4-CF₃Ph CF₃ 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5-yl H 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5-yl methyl 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5-yl i-propyl 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5-yl CF₃ 4-Cl-2-NO₂Ph 3-methyl-1,2,4-oxadiazol-5-yl H 4-Cl-2-NO₂Ph 3-methyl-1,2,4-oxadiazol-5-yl methyl 4-Cl-2-NO₂Ph 3-methyl-1,2,4-oxadiazol-5-yl i-propyl 4-Cl-2-NO₂Ph 3-methyl-1,2,4-oxadiazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph 3-methyl-1,2,4-oxadiazol-5-yl CF₃ 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- H oxadiazol-5-yl 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- methyl oxadiazol-5-yl 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- i-propyl oxadiazol-5-yl 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-5-yl 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- CF₃ oxadiazol-5-yl 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3-yl H 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3-yl methyl 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3-yl i-propyl 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3-yl cyclopropyl 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3-yl CF₃ 4-Cl-2-NO₂Ph 5-methyl-1,2,4-oxadiazol-3-yl H 4-Cl-2-NO₂Ph 5-methyl-1,2,4-oxadiazol-3-yl methyl 4-Cl-2-NO₂Ph 5-methyl-1,2,4-oxadiazol-3-yl i-propyl 4-Cl-2-NO₂Ph 5-methyl-1,2,4-oxadiazol-3-yl cyclopropyl 4-Cl-2-NO₂Ph 5-methyl-1,2,4-oxadiazol-3-yl CF₃ 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- H oxadiazol-3-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- methyl oxadiazol-3-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- i-propyl oxadiazol-3-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-3-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- CF₃ oxadiazol-3-yl 4-Cl-2-NO₂Ph 5-chloro-1,2,4-oxadiazol-3-yl H 4-Cl-2-NO₂Ph 5-chloro-1,2,4-oxadiazol-3-yl methyl 4-Cl-2-NO₂Ph 5-chloro-1,2,4-oxadiazol-3-yl i-propyl 4-Cl-2-NO₂Ph 5-chloro-1,2,4-oxadiazol-3-yl cyclopropyl 4-Cl-2-NO₂Ph 5-chloro-1,2,4-oxadiazol-3-yl CF₃ 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2-yl H 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2-yl methyl 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2-yl i-propyl 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2-yl CF₃ 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- H oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- methyl oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- i-propyl oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- cyclopropyl oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- CF₃ oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-methyl-1,3,4-oxadiazol-2-yl H 4-Cl-2-NO₂Ph 5-methyl-1,3,4-oxadiazol-2-yl methyl 4-Cl-2-NO₂Ph 5-methyl-1,3,4-oxadiazol-2-yl i-propyl 4-Cl-2-NO₂Ph 5-methyl-1,3,4-oxadiazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 5-methyl-1,3,4-oxadiazol-2-yl CF₃ 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,3,4- H oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,3,4- methyl oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,3,4- i-propyl oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,3,4- cyclopropyl oxadiazol-2-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,3,4- CF₃ oxadiazol-2-yl 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl H 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl methyl 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl i-propyl 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl cyclopropyl 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl CF₃ 4-Cl-2-NO₂Ph 1-methyl-1,2,3-triazol-4-yl H 4-Cl-2-NO₂Ph 1-methyl-1,2,3-triazol-4-yl methyl 4-Cl-2-NO₂Ph 1-methyl-1,2,3-triazol-4-yl i-propyl 4-Cl-2-NO₂Ph 1-methyl-1,2,3-triazol-4-yl cyclopropyl 4-Cl-2-NO₂Ph 1-methyl-1,2,3-triazol-4-yl CF₃ 4-Cl-2-NO₂Ph 2-methyl-1,2,3-triazol-4-yl H 4-Cl-2-NO₂Ph 2-methyl-1,2,3-triazol-4-yl methyl 4-Cl-2-NO₂Ph 2-methyl-1,2,3-triazol-4-yl i-propyl 4-Cl-2-NO₂Ph 2-methyl-1,2,3-triazol-4-yl cyclopropyl 4-Cl-2-NO₂Ph 2-methyl-1,2,3-triazol-4-yl CF₃ 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl H 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl methyl 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl i-propyl 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl cyclopropyl 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl CF₃ 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl H 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl methyl 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl i-propyl 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl CF₃ 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl H 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl methyl 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl i-propyl 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl cyclopropyl 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl CF₃ 4-Cl-2-NO₂Ph imidazol-2-yl H 4-Cl-2-NO₂Ph imidazol-2-yl methyl 4-Cl-2-NO₂Ph imidazol-2-yl i-propyl 4-Cl-2-NO₂Ph imidazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph imidazol-2-yl CF₃ 4-Cl-2-NO₂Ph imidazol-1-yl H 4-Cl-2-NO₂Ph imidazol-1-yl methyl 4-Cl-2-NO₂Ph imidazol-1-yl i-propyl 4-Cl-2-NO₂Ph imidazol-1-yl cyclopropyl 4-Cl-2-NO₂Ph imidazol-1-yl CF₃ 4-Cl-2-NO₂Ph imidazol-4-yl H 4-Cl-2-NO₂Ph imidazol-4-yl methyl 4-Cl-2-NO₂Ph imidazol-4-yl i-propyl 4-Cl-2-NO₂Ph imidazol-4-yl cyclopropyl 4-Cl-2-NO₂Ph imidazol-4-yl CF₃ 4-Cl-2-NO₂Ph thiazol-2-yl H 4-Cl-2-NO₂Ph thiazol-2-yl methyl 4-Cl-2-NO₂Ph thiazol-2-yl i-propyl 4-Cl-2-NO₂Ph thiazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph thiazol-2-yl CF₃ 4-Cl-2-NO₂Ph 4-methylthiazol-2-yl H 4-Cl-2-NO₂Ph 4-methylthiazol-2-yl methyl 4-Cl-2-NO₂Ph 4-methylthiazol-2-yl i-propyl 4-Cl-2-NO₂Ph 4-methylthiazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 4-methylthiazol-2-yl CF₃ 4-Cl-2-NO₂Ph oxazol-2-yl H 4-Cl-2-NO₂Ph oxazol-2-yl methyl 4-Cl-2-NO₂Ph oxazol-2-yl i-propyl 4-Cl-2-NO₂Ph oxazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph oxazol-2-yl CF₃ 4-Cl-2-NO₂Ph 4,5-dimethyloxazol-2-yl H 4-Cl-2-NO₂Ph 4,5-dimethyloxazol-2-yl methyl 4-Cl-2-NO₂Ph 4,5-dimethyloxazol-2-yl i-propyl 4-Cl-2-NO₂Ph 4,5-dimethyloxazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 4,5-dimethyloxazol-2-yl CF₃ 4-Cl-2-NO₂Ph 2-oxazolin-2-yl H 4-Cl-2-NO₂Ph 2-oxazolin-2-yl methyl 4-Cl-2-NO₂Ph 2-oxazolin-2-yl i-propyl 4-Cl-2-NO₂Ph 2-oxazolin-2-yl cyclopropyl 4-Cl-2-NO₂Ph 2-oxazolin-2-yl CF₃ 4-Cl-2-NO₂Ph 4,4-dimethyl-2-oxazolin-2-yl H 4-Cl-2-NO₂Ph 4,4-dimethyl-2-oxazolin-2-yl methyl 4-Cl-2-NO₂Ph 4,4-dimethyl-2-oxazolin-2-yl i-propyl 4-Cl-2-NO₂Ph 4,4-dimethyl-2-oxazolin-2-yl cyclopropyl 4-Cl-2-NO₂Ph 4,4-dimethyl-2-oxazolin-2-yl CF₃ 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-5-yl H 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-5-yl methyl 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-5-yl i-propyl 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-5-yl CF₃ 4-Cl-2-NO₂Ph 3-methyl-1,2,4-thiadiazol-5-yl H 4-Cl-2-NO₂Ph 3-methyl-1,2,4-thiadiazol-5-yl methyl 4-Cl-2-NO₂Ph 3-methyl-1,2,4-thiadiazol-5-yl i-propyl 4-Cl-2-NO₂Ph 3-methyl-1,2,4-thiadiazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph 3-methyl-1,2,4-thiadiazol-5-yl CF₃ 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- H thiadiazol-5-yl 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- methyl thiadiazol-5-yl 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- i-propyl thiadiazol-5-yl 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-5-yl 4-Cl-2-NO₂Ph 3-trifluoromethyl-1,2,4- CF₃ thiadiazol-5-yl 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-3-yl H 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-3-yl methyl 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-3-yl i-propyl 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-3-yl cyclopropyl 4-Cl-2-NO₂Ph 1,2,4-thiadiazol-3-yl CF₃ 4-Cl-2-NO₂Ph 5-methyl-1,2,4-thiadiazol-3-yl H 4-Cl-2-NO₂Ph 5-methyl-1,2,4-thiadiazol-3-yl methyl 4-Cl-2-NO₂Ph 5-methyl-1,2,4-thiadiazol-3-yl i-propyl 4-Cl-2-NO₂Ph 5-methyl-1,2,4-thiadiazol-3-yl cyclopropyl 4-Cl-2-NO₂Ph 5-methyl-1,2,4-thiadiazol-3-yl CF₃ 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- H thiadiazol-3-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- methyl thiadiazol-3-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- i-propyl thiadiazol-3-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-3-yl 4-Cl-2-NO₂Ph 5-trifluoromethyl-1,2,4- CF₃ thiadiazol-3-yl 4-Cl-2-NO₂Ph 1,3,4-thiadiazol-2-yl H 4-Cl-2-NO₂Ph 1,3,4-thiadiazol-2-yl methyl 4-Cl-2-NO₂Ph 1,3,4-thiadiazol-2-yl i-propyl 4-Cl-2-NO₂Ph 1,3,4-thiadiazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 1,3,4-thiadiazol-2-yl CF₃ 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- H thiadiazol-2-yl 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- methyl thiadiazol-2-yl 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- i-propyl thiadiazol-2-yl 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- cyclopropyl thiadiazol-2-yl 4-Cl-2-NO₂Ph 5-methylsulfonyl-1,3,4- CF₃ thiadiazol-2-yl 4-Cl-2-NO₂Ph 5-methyl-1,3,4-thiadiazol-2-yl H 4-Cl-2-NO₂Ph 5-methyl-1,3,4-thiadiazol-2-yl methyl 4-Cl-2-NO₂Ph 5-methyl-1,3,4-thiadiazol-2-yl i-propyl 4-Cl-2-NO₂Ph 5-methyl-1,3,4-thiadiazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 5-methyl-1,3,4-thiadiazol-2-yl CF₃ 4-Cl-2-NO₂Ph benzoxazol-2-yl H 4-Cl-2-NO₂Ph benzoxazol-2-yl methyl 4-Cl-2-NO₂Ph benzoxazol-2-yl i-propyl 4-Cl-2-NO₂Ph benzoxazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph benzoxazol-2-yl CF₃ 4-Cl-2-NO₂Ph 6-methylbenzoxazol-2-yl H 4-Cl-2-NO₂Ph 6-methylbenzoxazol-2-yl methyl 4-Cl-2-NO₂Ph 6-methylbenzoxazol-2-yl i-propyl 4-Cl-2-NO₂Ph 6-methylbenzoxazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 6-methylbenzoxazol-2-yl CF₃ 4-Cl-2-NO₂Ph benzothiazol-2-yl H 4-Cl-2-NO₂Ph benzothiazol-2-yl methyl 4-Cl-2-NO₂Ph benzothiazol-2-yl i-propyl 4-Cl-2-NO₂Ph benzothiazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph benzothiazol-2-yl CF₃ 4-Cl-2-NO₂Ph pyrazol-1-yl H 4-Cl-2-NO₂Ph pyrazol-1-yl methyl 4-Cl-2-NO₂Ph pyrazol-1-yl i-propyl 4-Cl-2-NO₂Ph pyrazol-1-yl cyclopropyl 4-Cl-2-NO₂Ph pyrazol-1-yl CF₃ 4-Cl-2-NO₂Ph pyrazol-3-yl H 4-Cl-2-NO₂Ph pyrazol-3-yl methyl 4-Cl-2-NO₂Ph pyrazol-3-yl i-propyl 4-Cl-2-NO₂Ph pyrazol-3-yl cyclopropyl 4-Cl-2-NO₂Ph pyrazol-3-yl CF₃ 4-Cl-2-NO₂Ph 1-methylpyrazol-3-yl H 4-Cl-2-NO₂Ph 1-methylpyrazol-3-yl methyl 4-Cl-2-NO₂Ph 1-methylpyrazol-3-yl i-propyl 4-Cl-2-NO₂Ph 1-methylpyrazol-3-yl cyclopropyl 4-Cl-2-NO₂Ph 1-methylpyrazol-3-yl CF₃ 4-Cl-2-NO₂Ph tetrazol-1-yl H 4-Cl-2-NO₂Ph tetrazol-1-yl methyl 4-Cl-2-NO₂Ph tetrazol-1-yl i-propyl 4-Cl-2-NO₂Ph tetrazol-1-yl cyclopropyl 4-Cl-2-NO₂Ph tetrazol-1-yl CF₃ 4-Cl-2-NO₂Ph 5-methyltetrazol-1-yl H 4-Cl-2-NO₂Ph 5-methyltetrazol-1-yl methyl 4-Cl-2-NO₂Ph 5-methyltetrazol-1-yl i-propyl 4-Cl-2-NO₂Ph 5-methyltetrazol-1-yl cyclopropyl 4-Cl-2-NO₂Ph 5-methyltetrazol-1-yl CF₃ 4-Cl-2-NO₂Ph tetrazol-2-yl H 4-Cl-2-NO₂Ph tetrazol-2-yl methyl 4-Cl-2-NO₂Ph tetrazol-2-yl i-propyl 4-Cl-2-NO₂Ph tetrazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph tetrazol-2-yl CF₃ 4-Cl-2-NO₂Ph 5-methyltetrazol-2-yl H 4-Cl-2-NO₂Ph 5-methyltetrazol-2-yl methyl 4-Cl-2-NO₂Ph 5-methyltetrazol-2-yl i-propyl 4-Cl-2-NO₂Ph 5-methyltetrazol-2-yl cyclopropyl 4-Cl-2-NO₂Ph 5-methyltetrazol-2-yl CF₃ 4-Cl-2-NO₂Ph 1-methyltetrazol-5-yl H 4-Cl-2-NO₂Ph 1-methyltetrazol-5-yl methyl 4-Cl-2-NO₂Ph 1-methyltetrazol-5-yl i-propyl 4-Cl-2-NO₂Ph 1-methyltetrazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph 1-methyltetrazol-5-yl CF₃ 2-Cl-4-NO₂Ph 2-methyltetrazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph 2-methyltetrazol-5-yl methyl 4-Cl-2-NO₂Ph 2-methyltetrazol-5-yl i-propyl 4-Cl-2-NO₂Ph 2-methyltetrazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph 2-methyltetrazol-5-yl CF₃ 2,4-(NO₂)₂Ph 2-methyltetrazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph pyridin-2-yl methyl 4-Cl-2-NO₂Ph pyridin-2-yl i-propyl 4-Cl-2-NO₂Ph pyridin-2-yl cyclopropyl 4-Cl-2-NO₂Ph pyridin-2-yl CF₃ 4-Cl-2-NO₂Ph pyridin-4-yl H 4-Cl-2-NO₂Ph pyridin-4-yl methyl 4-Cl-2-NO₂Ph pyridin-4-yl i-propyl 4-Cl-2-NO₂Ph pyridin-4-yl cyclopropyl 4-Cl-2-NO₂Ph pyridin-4-yl CF₃ 4-Cl-2-NO₂Ph pyridin-3-yl H 4-Cl-2-NO₂Ph pyridin-3-yl methyl 4-Cl-2-NO₂Ph pyridin-3-yl i-propyl 4-Cl-2-NO₂Ph pyridin-3-yl cyclopropyl 4-Cl-2-NO₂Ph pyridin-3-yl CF₃ 4-Cl-2-NO₂Ph 3-nitropyridin-4-yl H 4-Cl-2-NO₂Ph 3-nitropyridin-4-yl methyl 4-Cl-2-NO₂Ph 3-nitropyridin-4-yl i-propyl 4-Cl-2-NO₂Ph 3-nitropyridin-4-yl cyclopropyl 4-Cl-2-NO₂Ph 3-nitropyridin-4-yl CF₃ 4-Cl-2-NO₂Ph 5-cyanopyridin-2-yl H 4-Cl-2-NO₂Ph 5-cyanopyridin-2-yl methyl 4-Cl-2-NO₂Ph 5-cyanopyridin-2-yl i-propyl 4-Cl-2-NO₂Ph 5-cyanopyridin-2-yl cyclopropyl 4-Cl-2-NO₂Ph 5-cyanopyridin-2-yl CF₃ 4-Cl-2-NO₂Ph 5-trifluoromethylpyridin-2-yl H 4-Cl-2-NO₂Ph 5-trifluoromethylpyridin-2-yl methyl 4-Cl-2-NO₂Ph 5-trifluoromethylpyridin-2-yl i-propyl 4-Cl-2-NO₂Ph 5-trifluoromethylpyridin-2-yl cyclopropyl 4-Cl-2-NO₂Ph 5-trifluoromethylpyridin-2-yl CF₃ 4-Cl-2-NO₂Ph pyrimidin-2-yl H 4-Cl-2-NO₂Ph pyrimidin-2-yl methyl 4-Cl-2-NO₂Ph pyrimidin-2-yl i-propyl 4-Cl-2-NO₂Ph pyrimidin-2-yl cyclopropyl 4-Cl-2-NO₂Ph pyrimidin-2-yl CF₃ 4-Cl-2-NO₂Ph pyrimidin-4-yl H 4-Cl-2-NO₂Ph pyrimidin-4-yl methyl 4-Cl-2-NO₂Ph pyrimidin-4-yl i-propyl 4-Cl-2-NO₂Ph pyrimidin-4-yl cyclopropyl 4-Cl-2-NO₂Ph pyrimidin-4-yl CF₃ 4-Cl-2-NO₂Ph 6-chloropyrimidin-4-yl methyl 4-Cl-2-NO₂Ph 6-chloropyrimidin-4-yl i-propyl 4-Cl-2-NO₂Ph 6-chloropyrimidin-4-yl cyclopropyl 4-Cl-2-NO₂Ph 6-chloropyrimidin-4-yl CF₃ 2,4-(Cl)₂Ph 1-methyltetrazol-5-yl t-butil 4-Cl-2-NO₂Ph pyridazin-3-yl methyl 4-Cl-2-NO₂Ph pyridazin-3-yl i-propyl 4-Cl-2-NO₂Ph pyridazin-3-yl cyclopropyl 4-Cl-2-NO₂Ph pyridazin-3-yl CF₃ 4-Cl-2-NO₂Ph 6-chloropyridazin-3-yl methyl 4-Cl-2-NO₂Ph 6-chloropyridazin-3-yl i-propyl 4-Cl-2-NO₂Ph 6-chloropyridazin-3-yl cyclopropyl 4-Cl-2-NO₂Ph 6-chloropyridazin-3-yl CF₃ 4-Cl-2-NO₂Ph pyrazin-2-yl methyl 4-Cl-2-NO₂Ph pyrazin-2-yl i-propyl 4-Cl-2-NO₂Ph pyrazin-2-yl cyclopropyl 4-Cl-2-NO₂Ph pyrazin-2-yl CF₃ 4-Cl-2-NO₂Ph triazin-2-yl methyl 4-Cl-2-NO₂Ph triazin-2-yl i-propyl 4-Cl-2-NO₂Ph triazin-2-yl cyclopropyl 4-Cl-2-NO₂Ph triazin-2-yl CF₃ 4-Cl-2-NO₂Ph quinolin-2-yl methyl 4-Cl-2-NO₂Ph quinolin-2-yl i-propyl 4-Cl-2-NO₂Ph quinolin-2-yl cyclopropyl 4-Cl-2-NO₂Ph quinolin-2-yl CF₃ 4-Cl-2-NO₂Ph 4,4,6-trimethyl-5,6-dihydro- H 1,3(4H)-oxazin-2-yl 4-Cl-2-NO₂Ph 4,4,6-trimethyl-5,6-dihydro- methyl 1,3(4H)-oxazin-2-yl 4-Cl-2-NO₂Ph 4,4,6-trimethyl-5,6-dihydro- i-propyl 1,3(4H)-oxazin-2-yl 4-Cl-2-NO₂Ph 4,4,6-trimethyl-5,6-dihydro- cyclopropyl 1,3(4H)-oxazin-2-yl 4-Cl-2-NO₂Ph 4,4,6-trimethyl-5,6-dihydro- CF₃ 1,3(4H)-oxazin-2-yl 4-Cl-2-NO₂Ph 2-oxazolidinon-3-yl H 4-Cl-2-NO₂Ph 2-oxazolidinon-3-yl methyl 4-Cl-2-NO₂Ph 2-oxazolidinon-3-yl i-propyl 4-Cl-2-NO₂Ph 2-oxazolidinon-3-yl cyclopropyl 4-Cl-2-NO₂Ph 2-oxazolidinon-3-yl CF₃ 4-Cl-2-NO₂Ph 2-pyrrolidinon-1-yl methyl 4-Cl-2-NO₂Ph 2-pyrrolidinon-1-yl i-propyl 4-Cl-2-NO₂Ph 2-pyrrolidinon-1-yl cyclopropyl 4-Cl-2-NO₂Ph 2-pyrrolidinon-1-yl CF₃ 4-Cl-2-NO₂Ph 3-methylisoxazol-5-yl methyl 4-Cl-2-NO₂Ph 3-methylisoxazol-5-yl i-propyl 4-Cl-2-NO₂Ph 3-methylisoxazol-5-yl cyclopropyl 4-Cl-2-NO₂Ph 3-methylisoxazol-5-yl CF₃ 4-Cl-2-NO₂Ph 2-NO₂-4-SO₂MePh H 4-Cl-2-NO₂Ph 2-NO₂-4-SO₂MePh methyl 4-Cl-2-NO₂Ph 2-NO₂-4-SO₂MePh i-propyl 4-Cl-2-NO₂Ph 2-NO₂-4-SO₂MePh cyclopropyl 4-Cl-2-NO₂Ph 2-NO₂-4-SO₂MePh CF₃ 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePh H 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePh methyl 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePh i-propyl 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePh cyclopropyl 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePh CF₃ 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph H 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph methyl 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph i-propyl 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph cyclopropyl 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph CF₃ 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh H 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh methyl 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh i-propyl 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh cyclopropyl 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh CF₃ 4-Cl-2-NO₂Ph 2-Cl-4-NO₂Ph H 4-Cl-2-NO₂Ph 2-Cl-4-NO₂Ph methyl 4-Cl-2-NO₂Ph 2-Cl-4-NO₂Ph i-propyl 4-Cl-2-NO₂Ph 2-Cl-4-NO₂Ph cyclopropyl 4-Cl-2-NO₂Ph 2-Cl-4-NO₂Ph CF₃ 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph H 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph methyl 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph i-propyl 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph cyclopropyl 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph CF₃ 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph H 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph methyl 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph i-propyl 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph cyclopropyl 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph CF₃ 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph H 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph methyl 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph i-propyl 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph cyclopropyl 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph CF₃ 4-Cl-2-NO₂Ph 2-SO₂Me-4-CF₃Ph H 4-Cl-2-NO₂Ph 2-SO₂Me-4-CF₃Ph methyl 4-Cl-2-NO₂Ph 2-SO₂Me-4-CF₃Ph i-propyl 4-Cl-2-NO₂Ph 2-SO₂Me-4-CF₃Ph cyclopropyl 4-Cl-2-NO₂Ph 2-SO₂Me-4-CF₃Ph CF₃ 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-5-yl H 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-5-yl methyl 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-5-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-5-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-5-yl CF₃ 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-oxadiazol-5-yl H 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-oxadiazol-5-yl methyl 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-oxadiazol-5-yl i-propyl 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-oxadiazol-5-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-oxadiazol-5-yl CF₃ 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- H oxadiazol-5-yl 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- methyl oxadiazol-5-yl 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- i-propyl oxadiazol-5-yl 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-5-yl 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- CF₃ oxadiazol-5-yl 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-3-yl H 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-3-yl methyl 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-3-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,2,4-oxadiazol-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-oxadiazol-3-yl H 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-oxadiazol-3-yl methyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-oxadiazol-3-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-oxadiazol-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-oxadiazol-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- H oxadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- methyl oxadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- i-propyl oxadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- CF₃ oxadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-chloro-1,2,4-oxadiazol-3-yl H 2-SO₂Me-4-CF₃Ph 5-chloro-1,2,4-oxadiazol-3-yl methyl 2-SO₂Me-4-CF₃Ph 5-chloro-1,2,4-oxadiazol-3-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-chloro-1,2,4-oxadiazol-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-chloro-1,2,4-oxadiazol-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 1,3,4-oxadiazol-2-yl H 2-SO₂Me-4-CF₃Ph 1,3,4-oxadiazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 1,3,4-oxadiazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,3,4-oxadiazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,3,4-oxadiazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- H oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- methyl oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- i-propyl oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- cyclopropyl oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- CF₃ oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-oxadiazol-2-yl H 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-oxadiazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-oxadiazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-oxadiazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-oxadiazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,3,4- H oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,3,4- methyl oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,3,4- i-propyl oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,3,4- cyclopropyl oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,3,4- CF₃ oxadiazol-2-yl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-4-yl H 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-4-yl methyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-4-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-4-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-4-yl CF₃ 2-SO₂Me-4-CF₃Ph 1-methyl-1,2,3-triazol-4-yl H 2-SO₂Me-4-CF₃Ph 1-methyl-1,2,3-triazol-4-yl methyl 2-SO₂Me-4-CF₃Ph 1-methyl-1,2,3-triazol-4-yl i-propyl 2-SO₂Me-4-CF₃Ph 1-methyl-1,2,3-triazol-4-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1-methyl-1,2,3-triazol-4-yl CF₃ 2-SO₂Me-4-CF₃Ph 2-methyl-1,2,3-triazol-4-yl H 2-SO₂Me-4-CF₃Ph 2-methyl-1,2,3-triazol-4-yl methyl 2-SO₂Me-4-CF₃Ph 2-methyl-1,2,3-triazol-4-yl i-propyl 2-SO₂Me-4-CF₃Ph 2-methyl-1,2,3-triazol-4-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 2-methyl-1,2,3-triazol-4-yl CF₃ 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-1-yl H 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-1-yl methyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-1-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-1-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-1-yl CF₃ 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-2-yl H 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,2,3-triazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 1,2,4-triazol-1-yl H 2-SO₂Me-4-CF₃Ph 1,2,4-triazol-1-yl methyl 2-SO₂Me-4-CF₃Ph 1,2,4-triazol-1-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,2,4-triazol-1-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,2,4-triazol-1-yl CF₃ 2-SO₂Me-4-CF₃Ph imidazol-2-yl H 2-SO₂Me-4-CF₃Ph imidazol-2-yl methyl 2-SO₂Me-4-CF₃Ph imidazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph imidazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph imidazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph imidazol-1-yl H 2-SO₂Me-4-CF₃Ph imidazol-1-yl methyl 2-SO₂Me-4-CF₃Ph imidazol-1-yl i-propyl 2-SO₂Me-4-CF₃Ph imidazol-1-yl cyclopropyl 2-SO₂Me-4-CF₃Ph imidazol-1-yl CF₃ 2-SO₂Me-4-CF₃Ph imidazol-4-yl H 2-SO₂Me-4-CF₃Ph imidazol-4-yl methyl 2-SO₂Me-4-CF₃Ph imidazol-4-yl i-propyl 2-SO₂Me-4-CF₃Ph imidazol-4-yl cyclopropyl 2-SO₂Me-4-CF₃Ph imidazol-4-yl CF₃ 2-SO₂Me-4-CF₃Ph thiazol-2-yl H 2-SO₂Me-4-CF₃Ph thiazol-2-yl methyl 2-SO₂Me-4-CF₃Ph thiazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph thiazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph thiazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 4-methylthiazol-2-yl H 2-SO₂Me-4-CF₃Ph 4-methylthiazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 4-methylthiazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 4-methylthiazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 4-methylthiazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph oxazol-2-yl H 2-SO₂Me-4-CF₃Ph oxazol-2-yl methyl 2-SO₂Me-4-CF₃Ph oxazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph oxazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph oxazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 4,5-dimethyloxazol-2-yl H 2-SO₂Me-4-CF₃Ph 4,5-dimethyloxazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 4,5-dimethyloxazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 4,5-dimethyloxazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 4,5-dimethyloxazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 2-oxazolin-2-yl H 2-SO₂Me-4-CF₃Ph 2-oxazolin-2-yl methyl 2-SO₂Me-4-CF₃Ph 2-oxazolin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 2-oxazolin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 2-oxazolin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 4,4-dimethyl-2-oxazolin-2-yl H 2-SO₂Me-4-CF₃Ph 4,4-dimethyl-2-oxazolin-2-yl methyl 2-SO₂Me-4-CF₃Ph 4,4-dimethyl-2-oxazolin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 4,4-dimethyl-2-oxazolin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 4,4-dimethyl-2-oxazolin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-5-yl H 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-5-yl methyl 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-5-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-5-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-5-yl CF₃ 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-thiadiazol-5-yl H 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-thiadiazol-5-yl methyl 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-thiadiazol-5-yl i-propyl 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-thiadiazol-5-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 3-methyl-1,2,4-thiadiazol-5-yl CF₃ 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- H thiadiazol-5-yl 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- methyl thiadiazol-5-yl 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- i-propyl thiadiazol-5-yl 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-5-yl 2-SO₂Me-4-CF₃Ph 3-trifluoromethyl-1,2,4- CF₃ thiadiazol-5-yl 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-3-yl H 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-3-yl methyl 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-3-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,2,4-thiadiazol-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-thiadiazol-3-yl H 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-thiadiazol-3-yl methyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-thiadiazol-3-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-thiadiazol-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,2,4-thiadiazol-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- H thiadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- methyl thiadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- i-propyl thiadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-3-yl 2-SO₂Me-4-CF₃Ph 5-trifluoromethyl-1,2,4- CF₃ thiadiazol-3-yl 2-SO₂Me-4-CF₃Ph 1,3,4-thiadiazol-2-yl H 2-SO₂Me-4-CF₃Ph 1,3,4-thiadiazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 1,3,4-thiadiazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 1,3,4-thiadiazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1,3,4-thiadiazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- H thiadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- methyl thiadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- i-propyl thiadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- cyclopropyl thiadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methylsulfonyl-1,3,4- CF₃ thiadiazol-2-yl 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-thiadiazol-2-yl H 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-thiadiazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-thiadiazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-thiadiazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-methyl-1,3,4-thiadiazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph benzoxazol-2-yl H 2-SO₂Me-4-CF₃Ph benzoxazol-2-yl methyl 2-SO₂Me-4-CF₃Ph benzoxazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph benzoxazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph benzoxazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 6-methylbenzoxazol-2-yl H 2-SO₂Me-4-CF₃Ph 6-methylbenzoxazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 6-methylbenzoxazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 6-methylbenzoxazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 6-methylbenzoxazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph benzothiazol-2-yl H 2-SO₂Me-4-CF₃Ph benzothiazol-2-yl methyl 2-SO₂Me-4-CF₃Ph benzothiazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph benzothiazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph benzothiazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph pyrazol-1-yl H 2-SO₂Me-4-CF₃Ph pyrazol-1-yl methyl 2-SO₂Me-4-CF₃Ph pyrazol-1-yl i-propyl 2-SO₂Me-4-CF₃Ph pyrazol-1-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyrazol-1-yl CF₃ 2-SO₂Me-4-CF₃Ph pyrazol-3-yl H 2-SO₂Me-4-CF₃Ph pyrazol-3-yl methyl 2-SO₂Me-4-CF₃Ph pyrazol-3-yl i-propyl 2-SO₂Me-4-CF₃Ph pyrazol-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyrazol-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 1-methylpyrazol-3-yl H 2-SO₂Me-4-CF₃Ph 1-methylpyrazol-3-yl methyl 2-SO₂Me-4-CF₃Ph 1-methylpyrazol-3-yl i-propyl 2-SO₂Me-4-CF₃Ph 1-methylpyrazol-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1-methylpyrazol-3-yl CF₃ 2-SO₂Me-4-CF₃Ph tetrazol-1-yl H 2-SO₂Me-4-CF₃Ph tetrazol-1-yl methyl 2-SO₂Me-4-CF₃Ph tetrazol-1-yl i-propyl 2-SO₂Me-4-CF₃Ph tetrazol-1-yl cyclopropyl 2-SO₂Me-4-CF₃Ph tetrazol-1-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-1-yl H 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-1-yl methyl 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-1-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-1-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-1-yl CF₃ 2-SO₂Me-4-CF₃Ph tetrazol-2-yl H 2-SO₂Me-4-CF₃Ph tetrazol-2-yl methyl 2-SO₂Me-4-CF₃Ph tetrazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph tetrazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph tetrazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-2-yl H 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-2-yl methyl 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-methyltetrazol-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 1-methyltetrazol-5-yl H 2-SO₂Me-4-CF₃Ph 1-methyltetrazol-5-yl methyl 2-SO₂Me-4-CF₃Ph 1-methyltetrazol-5-yl i-propyl 2-SO₂Me-4-CF₃Ph 1-methyltetrazol-5-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 1-methyltetrazol-5-yl CF₃ 2-SO₂Me-4-CF₃Ph 2-methyltetrazol-5-yl H 2-SO₂Me-4-CF₃Ph 2-methyltetrazol-5-yl methyl 2-SO₂Me-4-CF₃Ph 2-methyltetrazol-5-yl i-propyl 2-SO₂Me-4-CF₃Ph 2-methyltetrazol-5-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 2-methyltetrazol-5-yl CF₃ 2-SO₂Me-4-CF₃Ph pyridin-2-yl H 2-SO₂Me-4-CF₃Ph pyridin-2-yl methyl 2-SO₂Me-4-CF₃Ph pyridin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph pyridin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyridin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph pyridin-4-yl H 2-SO₂Me-4-CF₃Ph pyridin-4-yl methyl 2-SO₂Me-4-CF₃Ph pyridin-4-yl i-propyl 2-SO₂Me-4-CF₃Ph pyridin-4-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyridin-4-yl CF₃ 2-SO₂Me-4-CF₃Ph pyridin-3-yl H 2-SO₂Me-4-CF₃Ph pyridin-3-yl methyl 2-SO₂Me-4-CF₃Ph pyridin-3-yl i-propyl 2-SO₂Me-4-CF₃Ph pyridin-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyridin-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 3-nitropyridin-4-yl H 2-SO₂Me-4-CF₃Ph 3-nitropyridin-4-yl methyl 2-SO₂Me-4-CF₃Ph 3-nitropyridin-4-yl i-propyl 2-SO₂Me-4-CF₃Ph 3-nitropyridin-4-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 3-nitropyridin-4-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-cyanopyridin-2-yl H 2-SO₂Me-4-CF₃Ph 5-cyanopyridin-2-yl methyl 2-SO₂Me-4-CF₃Ph 5-cyanopyridin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-cyanopyridin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-cyanopyridin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 5-trifluoromethylpyridin-2-yl H 2-SO₂Me-4-CF₃Ph 5-trifluoromethylpyridin-2-yl methyl 2-SO₂Me-4-CF₃Ph 5-trifluoromethylpyridin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph 5-trifluoromethylpyridin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 5-trifluoromethylpyridin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph pyrimidin-2-yl H 2-SO₂Me-4-CF₃Ph pyrimidin-2-yl methyl 2-SO₂Me-4-CF₃Ph pyrimidin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph pyrimidin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyrimidin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph pyrimidin-4-yl H 2-SO₂Me-4-CF₃Ph pyrimidin-4-yl methyl 2-SO₂Me-4-CF₃Ph pyrimidin-4-yl i-propyl 2-SO₂Me-4-CF₃Ph pyrimidin-4-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyrimidin-4-yl CF₃ 2-SO₂Me-4-CF₃Ph 6-chloropyrimidin-4-yl methyl 2-SO₂Me-4-CF₃Ph 6-chloropyrimidin-4-yl i-propyl 2-SO₂Me-4-CF₃Ph 6-chloropyrimidin-4-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 6-chloropyrimidin-4-yl CF₃ 2-SO₂Me-4-CF₃Ph pyridazin-3-yl H 2-SO₂Me-4-CF₃Ph pyridazin-3-yl methyl 2-SO₂Me-4-CF₃Ph pyridazin-3-yl i-propyl 2-SO₂Me-4-CF₃Ph pyridazin-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyridazin-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 6-chloropyridazin-3-yl methyl 2-SO₂Me-4-CF₃Ph 6-chloropyridazin-3-yl i-propyl 2-SO₂Me-4-CF₃Ph 6-chloropyridazin-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 6-chloropyridazin-3-yl CF₃ 2-SO₂Me-4-CF₃Ph pyrazin-2-yl methyl 2-SO₂Me-4-CF₃Ph pyrazin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph pyrazin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph pyrazin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph triazin-2-yl methyl 2-SO₂Me-4-CF₃Ph triazin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph triazin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph triazin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph quinolin-2-yl methyl 2-SO₂Me-4-CF₃Ph quinolin-2-yl i-propyl 2-SO₂Me-4-CF₃Ph quinolin-2-yl cyclopropyl 2-SO₂Me-4-CF₃Ph quinolin-2-yl CF₃ 2-SO₂Me-4-CF₃Ph 4,4,6-trimethyl-5,6-dihydro- H 1,3(4H)-oxazin-2-yl 2-SO₂Me-4-CF₃Ph 4,4,6-trimethyl-5,6-dihydro- methyl 1,3(4H)-oxazin-2-yl 2-SO₂Me-4-CF₃Ph 4,4,6-trimethyl-5,6-dihydro- i-propyl 1,3(4H)-oxazin-2-yl 2-SO₂Me-4-CF₃Ph 4,4,6-trimethyl-5,6-dihydro- cyclopropyl 1,3(4H)-oxazin-2-yl 2-SO₂Me-4-CF₃Ph 4,4,6-trimethyl-5,6-dihydro- CF₃ 1,3(4H)-oxazin-2-yl 2-SO₂Me-4-CF₃Ph 2-oxazolidinon-3-yl H 2-SO₂Me-4-CF₃Ph 2-oxazolidinon-3-yl methyl 2-SO₂Me-4-CF₃Ph 2-oxazolidinon-3-yl i-propyl 2-SO₂Me-4-CF₃Ph 2-oxazolidinon-3-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 2-oxazolidinon-3-yl CF₃ 2-SO₂Me-4-CF₃Ph 2-pyrrolidinon-1-yl methyl 2-SO₂Me-4-CF₃Ph 2-pyrrolidinon-1-yl i-propyl 2-SO₂Me-4-CF₃Ph 2-pyrrolidinon-1-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 2-pyrrolidinon-1-yl CF₃ 2-SO₂Me-4-CF₃Ph 3-methylisoxazol-5-yl methyl 2-SO₂Me-4-CF₃Ph 3-methylisoxazol-5-yl i-propyl 2-SO₂Me-4-CF₃Ph 3-methylisoxazol-5-yl cyclopropyl 2-SO₂Me-4-CF₃Ph 3-methylisoxazol-5-yl CF₃ 2-SO₂Me-4-CF₃Ph 2-NO₂-4-SO₂MePh H 2-SO₂Me-4-CF₃Ph 2-NO₂-4-SO₂MePh methyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-SO₂MePh i-propyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-SO₂MePh cyclopropyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-SO₂MePh CF₃ 2-SO₂Me-4-CF₃Ph 2-Cl-4-SO₂MePh H 2-SO₂Me-4-CF₃Ph 2-Cl-4-SO₂MePh methyl 2-SO₂Me-4-CF₃Ph 2-Cl-4-SO₂MePh i-propyl 2-SO₂Me-4-CF₃Ph 2-Cl-4-SO₂MePh cyclopropyl 2-SO₂Me-4-CF₃Ph 2-Cl-4-SO₂MePh CF₃ 2-SO₂Me-4-CF₃Ph 2-NO₂-4-CF₃Ph H 2-SO₂Me-4-CF₃Ph 2-NO₂-4-CF₃Ph methyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-CF₃Ph i-propyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-CF₃Ph cyclopropyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-CF₃Ph CF₃ 2-SO₂Me-4-CF₃Ph 2-NO₂-4-ClPh H 2-SO₂Me-4-CF₃Ph 2-NO₂-4-ClPh methyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-ClPh i-propyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-ClPh cyclopropyl 2-SO₂Me-4-CF₃Ph 2-NO₂-4-ClPh CF₃ 2-SO₂Me-4-CF₃Ph 2-Cl-4-NO₂Ph H 2-SO₂Me-4-CF₃Ph 2-Cl-4-NO₂Ph methyl 2-SO₂Me-4-CF₃Ph 2-Cl-4-NO₂Ph i-propyl 2-SO₂Me-4-CF₃Ph 2-Cl-4-NO₂Ph cyclopropyl 2-SO₂Me-4-CF₃Ph 2-Cl-4-NO₂Ph CF₃ 2-SO₂Me-4-CF₃Ph 2,4-(NO₂)₂Ph H 2-SO₂Me-4-CF₃Ph 2,4-(NO₂)₂Ph methyl 2-SO₂Me-4-CF₃Ph 2,4-(NO₂)₂Ph i-propyl 2-SO₂Me-4-CF₃Ph 2,4-(NO₂)₂Ph cyclopropyl 2-SO₂Me-4-CF₃Ph 2,4-(NO₂)₂Ph CF₃ 2-SO₂Me-4-CF₃Ph 4-F-3-NO₂Ph H 2-SO₂Me-4-CF₃Ph 4-F-3-NO₂Ph methyl 2-SO₂Me-4-CF₃Ph 4-F-3-NO₂Ph i-propyl 2-SO₂Me-4-CF₃Ph 4-F-3-NO₂Ph cyclopropyl 2-SO₂Me-4-CF₃Ph 4-F-3-NO₂Ph CF₃ 2-SO₂Me-4-CF₃Ph 3,5-(CF₃)₂Ph H 2-SO₂Me-4-CF₃Ph 3,5-(CF₃)₂Ph methyl 2-SO₂Me-4-CF₃Ph 3,5-(CF₃)₂Ph i-propyl 2-SO₂Me-4-CF₃Ph 3,5-(CF₃)₂Ph cyclopropyl 2-SO₂Me-4-CF₃Ph 3,5-(CF₃)₂Ph CF₃ 2-SO₂Me-4-CF₃Ph 2-SO₂Me-4-CF₃Ph H 2-SO₂Me-4-CF₃Ph 2-SO₂Me-4-CF₃Ph methyl 2-SO₂Me-4-CF₃Ph 2-SO₂Me-4-CF₃Ph i-propyl 2-SO₂Me-4-CF₃Ph 2-SO₂Me-4-CF₃Ph cyclopropyl 2-SO₂Me-4-CF₃Ph 2-SO₂Me-4-CF₃Ph CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-5-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-5-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-5-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-5-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-5-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-oxadiazol-5-yl H 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-oxadiazol-5-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-oxadiazol-5-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-oxadiazol-5-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-oxadiazol-5-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- H oxadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- methyl oxadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- i-propyl oxadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- CF₃ oxadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-3-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-oxadiazol-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-oxadiazol-3-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-oxadiazol-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-oxadiazol-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-oxadiazol-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-oxadiazol-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- H oxadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- methyl oxadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- i-propyl oxadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- CF₃ oxadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-chloro-1,2,4-oxadiazol-3-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-chloro-1,2,4-oxadiazol-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-chloro-1,2,4-oxadiazol-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-chloro-1,2,4-oxadiazol-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-chloro-1,2,4-oxadiazol-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-oxadiazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-oxadiazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-oxadiazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-oxadiazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-oxadiazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- H oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- methyl oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- i-propyl oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- cyclopropyl oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- CF₃ oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-oxadiazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-oxadiazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-oxadiazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-oxadiazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-oxadiazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,3,4- H oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,3,4- methyl oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,3,4- i-propyl oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,3,4- cyclopropyl oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,3,4- CF₃ oxadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-4-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-4-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-4-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-4-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-4-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1-methyl-1,2,3-triazol-4-yl H 3-Cl-5-CF₃Pyridin-2-yl 1-methyl-1,2,3-triazol-4-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1-methyl-1,2,3-triazol-4-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1-methyl-1,2,3-triazol-4-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1-methyl-1,2,3-triazol-4-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-methyl-1,2,3-triazol-4-yl H 3-Cl-5-CF₃Pyridin-2-yl 2-methyl-1,2,3-triazol-4-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 2-methyl-1,2,3-triazol-4-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-methyl-1,2,3-triazol-4-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-methyl-1,2,3-triazol-4-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-1-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-1-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-1-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-1-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-1-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,3-triazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-triazol-1-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-triazol-1-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-triazol-1-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-triazol-1-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-triazol-1-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl imidazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl imidazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl imidazol-1-yl H 3-Cl-5-CF₃Pyridin-2-yl imidazol-1-yl methyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-1-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-1-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-1-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl imidazol-4-yl H 3-Cl-5-CF₃Pyridin-2-yl imidazol-4-yl methyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-4-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-4-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl imidazol-4-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl thiazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl thiazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl thiazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl thiazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl thiazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 4-methylthiazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 4-methylthiazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 4-methylthiazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 4-methylthiazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 4-methylthiazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl oxazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl oxazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl oxazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl oxazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl oxazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 4,5-dimethyloxazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 4,5-dimethyloxazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 4,5-dimethyloxazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 4,5-dimethyloxazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 4,5-dimethyloxazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolin-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 4,4-dimethyl-2-oxazolin-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 4,4-dimethyl-2-oxazolin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 4,4-dimethyl-2-oxazolin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 4,4-dimethyl-2-oxazolin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 4,4-dimethyl-2-oxazolin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-5-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-5-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-5-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-5-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-5-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-thiadiazol-5-yl H 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-thiadiazol-5-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-thiadiazol-5-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-thiadiazol-5-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 3-methyl-1,2,4-thiadiazol-5-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- H thiadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- methyl thiadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- i-propyl thiadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 3-trifluoromethyl-1,2,4- CF₃ thiadiazol-5-yl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-3-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,2,4-thiadiazol-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-thiadiazol-3-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-thiadiazol-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-thiadiazol-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-thiadiazol-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,2,4-thiadiazol-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- H thiadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- methyl thiadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- i-propyl thiadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethyl-1,2,4- CF₃ thiadiazol-3-yl 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-thiadiazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-thiadiazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-thiadiazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-thiadiazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1,3,4-thiadiazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- H thiadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- methyl thiadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- i-propyl thiadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- cyclopropyl thiadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methylsulfonyl-1,3,4- CF₃ thiadiazol-2-yl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-thiadiazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-thiadiazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-thiadiazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-thiadiazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyl-1,3,4-thiadiazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl benzoxazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl benzoxazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl benzoxazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl benzoxazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl benzoxazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 6-methylbenzoxazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 6-methylbenzoxazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 6-methylbenzoxazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 6-methylbenzoxazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 6-methylbenzoxazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl benzothiazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl benzothiazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl benzothiazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl benzothiazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl benzothiazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyrazol-1-yl H 3-Cl-5-CF₃Pyridin-2-yl pyrazol-1-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyrazol-1-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyrazol-1-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyrazol-1-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyrazol-3-yl H 3-Cl-5-CF₃Pyridin-2-yl pyrazol-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyrazol-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyrazol-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyrazol-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1-methylpyrazol-3-yl H 3-Cl-5-CF₃Pyridin-2-yl 1-methylpyrazol-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1-methylpyrazol-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1-methylpyrazol-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1-methylpyrazol-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl tetrazol-1-yl H 3-Cl-5-CF₃Pyridin-2-yl tetrazol-1-yl methyl 3-Cl-5-CF₃Pyridin-2-yl tetrazol-1-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl tetrazol-1-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl tetrazol-1-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-1-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-1-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-1-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-1-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-1-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl tetrazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl tetrazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl tetrazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl tetrazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl tetrazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-methyltetrazol-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 1-methyltetrazol-5-yl H 3-Cl-5-CF₃Pyridin-2-yl 1-methyltetrazol-5-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 1-methyltetrazol-5-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 1-methyltetrazol-5-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 1-methyltetrazol-5-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-methyltetrazol-5-yl H 3-Cl-5-CF₃Pyridin-2-yl 2-methyltetrazol-5-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 2-methyltetrazol-5-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-methyltetrazol-5-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-methyltetrazol-5-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyridin-2-yl H 3-Cl-5-CF₃Pyridin-2-yl pyridin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyridin-4-yl H 3-Cl-5-CF₃Pyridin-2-yl pyridin-4-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-4-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-4-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-4-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyridin-3-yl H 3-Cl-5-CF₃Pyridin-2-yl pyridin-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyridin-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 3-nitropyridin-4-yl H 3-Cl-5-CF₃Pyridin-2-yl 3-nitropyridin-4-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 3-nitropyridin-4-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 3-nitropyridin-4-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 3-nitropyridin-4-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-cyanopyridin-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-cyanopyridin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-cyanopyridin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-cyanopyridin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-cyanopyridin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethylpyridin-2-yl H 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethylpyridin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethylpyridin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethylpyridin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 5-trifluoromethylpyridin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-2-yl H 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-4-yl H 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-4-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-4-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-4-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyrimidin-4-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 6-chloropyrimidin-4-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 6-chloropyrimidin-4-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 6-chloropyrimidin-4-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 6-chloropyrimidin-4-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyridazin-3-yl H 3-Cl-5-CF₃Pyridin-2-yl pyridazin-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyridazin-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyridazin-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyridazin-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 6-chloropyridazin-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 6-chloropyridazin-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 6-chloropyridazin-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 6-chloropyridazin-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl pyrazin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl pyrazin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl pyrazin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl pyrazin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl triazin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl triazin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl triazin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl triazin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl quinolin-2-yl methyl 3-Cl-5-CF₃Pyridin-2-yl quinolin-2-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl quinolin-2-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl quinolin-2-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 4,4,6-trimethyl-5,6-dihydro- H 1,3(4H)-oxazin-2-yl 3-Cl-5-CF₃Pyridin-2-yl 4,4,6-trimethyl-5,6-dihydro- methyl 1,3(4H)-oxazin-2-yl 3-Cl-5-CF₃Pyridin-2-yl 4,4,6-trimethyl-5,6-dihydro- i-propyl 1,3(4H)-oxazin-2-yl 3-Cl-5-CF₃Pyridin-2-yl 4,4,6-trimethyl-5,6-dihydro- cyclopropyl 1,3(4H)-oxazin-2-yl 3-Cl-5-CF₃Pyridin-2-yl 4,4,6-trimethyl-5,6-dihydro- CF₃ 1,3(4H)-oxazin-2-yl 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolidinon-3-yl H 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolidinon-3-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolidinon-3-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolidinon-3-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-oxazolidinon-3-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-pyrrolidinon-1-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 2-pyrrolidinon-1-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-pyrrolidinon-1-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-pyrrolidinon-1-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 3-methylisoxazol-5-yl methyl 3-Cl-5-CF₃Pyridin-2-yl 3-methylisoxazol-5-yl i-propyl 3-Cl-5-CF₃Pyridin-2-yl 3-methylisoxazol-5-yl cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 3-methylisoxazol-5-yl CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-SO₂MePh H 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-SO₂MePh methyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-SO₂MePh i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-SO₂MePh cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-SO₂MePh CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-SO₂MePh H 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-SO₂MePh methyl 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-SO₂MePh i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-SO₂MePh cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-SO₂MePh CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-CF₃Ph H 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-CF₃Ph methyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-CF₃Ph i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-CF₃Ph cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-CF₃Ph CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-ClPh H 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-ClPh methyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-ClPh i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-ClPh cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-NO₂-4-ClPh CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-NO₂Ph H 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-NO₂Ph methyl 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-NO₂Ph i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-NO₂Ph cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-Cl-4-NO₂Ph CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2,4-(NO₂)₂Ph H 3-Cl-5-CF₃Pyridin-2-yl 2,4-(NO₂)₂Ph methyl 3-Cl-5-CF₃Pyridin-2-yl 2,4-(NO₂)₂Ph i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2,4-(NO₂)₂Ph cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2,4-(NO₂)₂Ph CF₃ 3-Cl-5-CF₃Pyridin-2-yl 4-F-3-NO₂Ph H 3-Cl-5-CF₃Pyridin-2-yl 4-F-3-NO₂Ph methyl 3-Cl-5-CF₃Pyridin-2-yl 4-F-3-NO₂Ph i-propyl 3-Cl-5-CF₃Pyridin-2-yl 4-F-3-NO₂Ph cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 4-F-3-NO₂Ph CF₃ 3-Cl-5-CF₃Pyridin-2-yl 3,5-(CF₃)₂Ph H 3-Cl-5-CF₃Pyridin-2-yl 3,5-(CF₃)₂Ph methyl 3-Cl-5-CF₃Pyridin-2-yl 3,5-(CF₃)₂Ph i-propyl 3-Cl-5-CF₃Pyridin-2-yl 3,5-(CF₃)₂Ph cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 3,5-(CF₃)₂Ph CF₃ 3-Cl-5-CF₃Pyridin-2-yl 2-SO₂Me-4-CF₃Ph H 3-Cl-5-CF₃Pyridin-2-yl 2-SO₂Me-4-CF₃Ph methyl 3-Cl-5-CF₃Pyridin-2-yl 2-SO₂Me-4-CF₃Ph i-propyl 3-Cl-5-CF₃Pyridin-2-yl 2-SO₂Me-4-CF₃Ph cyclopropyl 3-Cl-5-CF₃Pyridin-2-yl 2-SO₂Me-4-CF₃Ph CF₃ 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-5-yl H 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-5-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-5-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-5-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-5-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-oxadiazol-5-yl H 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-oxadiazol-5-yl methyl 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-oxadiazol-5-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-oxadiazol-5-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-oxadiazol-5-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- H oxadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- methyl oxadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- i-propyl oxadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- CF₃ oxadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-3-yl H 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-3-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-oxadiazol-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-oxadiazol-3-yl H 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-oxadiazol-3-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-oxadiazol-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-oxadiazol-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-oxadiazol-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- H oxadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- methyl oxadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- i-propyl oxadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- cyclopropyl oxadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- CF₃ oxadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-chloro-1,2,4-oxadiazol-3-yl H 2,4-(Me)₂Thiazol-5-yl 5-chloro-1,2,4-oxadiazol-3-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-chloro-1,2,4-oxadiazol-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-chloro-1,2,4-oxadiazol-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-chloro-1,2,4-oxadiazol-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 1,3,4-oxadiazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 1,3,4-oxadiazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,3,4-oxadiazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,3,4-oxadiazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,3,4-oxadiazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- H oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- methyl oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- i-propyl oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- cyclopropyl oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- CF₃ oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-oxadiazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-oxadiazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-oxadiazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-oxadiazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-oxadiazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,3,4- H oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,3,4- methyl oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,3,4- i-propyl oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,3,4- cyclopropyl oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,3,4- CF₃ oxadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-4-yl H 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-4-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-4-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-4-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-4-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 1-methyl-1,2,3-triazol-4-yl H 2,4-(Me)₂Thiazol-5-yl 1-methyl-1,2,3-triazol-4-yl methyl 2,4-(Me)₂Thiazol-5-yl 1-methyl-1,2,3-triazol-4-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1-methyl-1,2,3-triazol-4-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1-methyl-1,2,3-triazol-4-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 2-methyl-1,2,3-triazol-4-yl H 2,4-(Me)₂Thiazol-5-yl 2-methyl-1,2,3-triazol-4-yl methyl 2,4-(Me)₂Thiazol-5-yl 2-methyl-1,2,3-triazol-4-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 2-methyl-1,2,3-triazol-4-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-methyl-1,2,3-triazol-4-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-1-yl H 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-1-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-1-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-1-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-1-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,2,3-triazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 1,2,4-triazol-1-yl H 2,4-(Me)₂Thiazol-5-yl 1,2,4-triazol-1-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-triazol-1-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-triazol-1-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-triazol-1-yl CF₃ 2,4-(Me)₂Thiazol-5-yl imidazol-2-yl H 2,4-(Me)₂Thiazol-5-yl imidazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl imidazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl imidazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl imidazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl imidazol-1-yl H 2,4-(Me)₂Thiazol-5-yl imidazol-1-yl methyl 2,4-(Me)₂Thiazol-5-yl imidazol-1-yl i-propyl 2,4-(Me)₂Thiazol-5-yl imidazol-1-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl imidazol-1-yl CF₃ 2,4-(Me)₂Thiazol-5-yl imidazol-4-yl H 2,4-(Me)₂Thiazol-5-yl imidazol-4-yl methyl 2,4-(Me)₂Thiazol-5-yl imidazol-4-yl i-propyl 2,4-(Me)₂Thiazol-5-yl imidazol-4-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl imidazol-4-yl CF₃ 2,4-(Me)₂Thiazol-5-yl thiazol-2-yl H 2,4-(Me)₂Thiazol-5-yl thiazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl thiazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl thiazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl thiazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 4-methylthiazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 4-methylthiazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 4-methylthiazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 4-methylthiazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 4-methylthiazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl oxazol-2-yl H 2,4-(Me)₂Thiazol-5-yl oxazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl oxazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl oxazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl oxazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 4,5-dimethyloxazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 4,5-dimethyloxazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 4,5-dimethyloxazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 4,5-dimethyloxazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 4,5-dimethyloxazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 2-oxazolin-2-yl H 2,4-(Me)₂Thiazol-5-yl 2-oxazolin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 2-oxazolin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 2-oxazolin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-oxazolin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 4,4-dimethyl-2-oxazolin-2-yl H 2,4-(Me)₂Thiazol-5-yl 4,4-dimethyl-2-oxazolin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 4,4-dimethyl-2-oxazolin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 4,4-dimethyl-2-oxazolin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 4,4-dimethyl-2-oxazolin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-5-yl H 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-5-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-5-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-5-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-5-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-thiadiazol-5-yl H 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-thiadiazol-5-yl methyl 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-thiadiazol-5-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-thiadiazol-5-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 3-methyl-1,2,4-thiadiazol-5-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- H thiadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- methyl thiadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- i-propyl thiadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 3-trifluoromethyl-1,2,4- CF₃ thiadiazol-5-yl 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-3-yl H 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-3-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,2,4-thiadiazol-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-thiadiazol-3-yl H 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-thiadiazol-3-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-thiadiazol-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-thiadiazol-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,2,4-thiadiazol-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- H thiadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- methyl thiadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- i-propyl thiadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- cyclopropyl thiadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethyl-1,2,4- CF₃ thiadiazol-3-yl 2,4-(Me)₂Thiazol-5-yl 1,3,4-thiadiazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 1,3,4-thiadiazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 1,3,4-thiadiazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1,3,4-thiadiazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1,3,4-thiadiazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- H thiadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- methyl thiadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- i-propyl thiadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- cyclopropyl thiadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methylsulfonyl-1,3,4- CF₃ thiadiazol-2-yl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-thiadiazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-thiadiazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-thiadiazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-thiadiazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-methyl-1,3,4-thiadiazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl benzoxazol-2-yl H 2,4-(Me)₂Thiazol-5-yl benzoxazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl benzoxazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl benzoxazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl benzoxazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 6-methylbenzoxazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 6-methylbenzoxazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 6-methylbenzoxazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 6-methylbenzoxazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 6-methylbenzoxazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl benzothiazol-2-yl H 2,4-(Me)₂Thiazol-5-yl benzothiazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl benzothiazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl benzothiazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl benzothiazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyrazol-1-yl H 2,4-(Me)₂Thiazol-5-yl pyrazol-1-yl methyl 2,4-(Me)₂Thiazol-5-yl pyrazol-1-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyrazol-1-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyrazol-1-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyrazol-3-yl H 2,4-(Me)₂Thiazol-5-yl pyrazol-3-yl methyl 2,4-(Me)₂Thiazol-5-yl pyrazol-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyrazol-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyrazol-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 1-methylpyrazol-3-yl H 2,4-(Me)₂Thiazol-5-yl 1-methylpyrazol-3-yl methyl 2,4-(Me)₂Thiazol-5-yl 1-methylpyrazol-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1-methylpyrazol-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1-methylpyrazol-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl tetrazol-1-yl H 2,4-(Me)₂Thiazol-5-yl tetrazol-1-yl methyl 2,4-(Me)₂Thiazol-5-yl tetrazol-1-yl i-propyl 2,4-(Me)₂Thiazol-5-yl tetrazol-1-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl tetrazol-1-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-1-yl H 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-1-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-1-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-1-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-1-yl CF₃ 2,4-(Me)₂Thiazol-5-yl tetrazol-2-yl H 2,4-(Me)₂Thiazol-5-yl tetrazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl tetrazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl tetrazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl tetrazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-2-yl H 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-methyltetrazol-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 1-methyltetrazol-5-yl H 2,4-(Me)₂Thiazol-5-yl 1-methyltetrazol-5-yl methyl 2,4-(Me)₂Thiazol-5-yl 1-methyltetrazol-5-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 1-methyltetrazol-5-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 1-methyltetrazol-5-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 2-methyltetrazol-5-yl H 2,4-(Me)₂Thiazol-5-yl 2-methyltetrazol-5-yl methyl 2,4-(Me)₂Thiazol-5-yl 2-methyltetrazol-5-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 2-methyltetrazol-5-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-methyltetrazol-5-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyridin-2-yl H 2,4-(Me)₂Thiazol-5-yl pyridin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl pyridin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyridin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyridin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyridin-4-yl H 2,4-(Me)₂Thiazol-5-yl pyridin-4-yl methyl 2,4-(Me)₂Thiazol-5-yl pyridin-4-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyridin-4-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyridin-4-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyridin-3-yl H 2,4-(Me)₂Thiazol-5-yl pyridin-3-yl methyl 2,4-(Me)₂Thiazol-5-yl pyridin-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyridin-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyridin-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 3-nitropyridin-4-yl H 2,4-(Me)₂Thiazol-5-yl 3-nitropyridin-4-yl methyl 2,4-(Me)₂Thiazol-5-yl 3-nitropyridin-4-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 3-nitropyridin-4-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 3-nitropyridin-4-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-cyanopyridin-2-yl H 2,4-(Me)₂Thiazol-5-yl 5-cyanopyridin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-cyanopyridin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-cyanopyridin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-cyanopyridin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethylpyridin-2-yl H 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethylpyridin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethylpyridin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethylpyridin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 5-trifluoromethylpyridin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyrimidin-2-yl H 2,4-(Me)₂Thiazol-5-yl pyrimidin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl pyrimidin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyrimidin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyrimidin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyrimidin-4-yl H 2,4-(Me)₂Thiazol-5-yl pyrimidin-4-yl methyl 2,4-(Me)₂Thiazol-5-yl pyrimidin-4-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyrimidin-4-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyrimidin-4-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 6-chloropyrimidin-4-yl methyl 2,4-(Me)₂Thiazol-5-yl 6-chloropyrimidin-4-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 6-chloropyrimidin-4-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 6-chloropyrimidin-4-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyridazin-3-yl H 2,4-(Me)₂Thiazol-5-yl pyridazin-3-yl methyl 2,4-(Me)₂Thiazol-5-yl pyridazin-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyridazin-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyridazin-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 6-chloropyridazin-3-yl methyl 2,4-(Me)₂Thiazol-5-yl 6-chloropyridazin-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 6-chloropyridazin-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 6-chloropyridazin-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl pyrazin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl pyrazin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl pyrazin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl pyrazin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl triazin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl triazin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl triazin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl triazin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl quinolin-2-yl methyl 2,4-(Me)₂Thiazol-5-yl quinolin-2-yl i-propyl 2,4-(Me)₂Thiazol-5-yl quinolin-2-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl quinolin-2-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 4,4,6-trimethyl-5,6-dihydro- H 1,3(4H)-oxazin-2-yl 2,4-(Me)₂Thiazol-5-yl 4,4,6-trimethyl-5,6-dihydro- methyl 1,3(4H)-oxazin-2-yl 2,4-(Me)₂Thiazol-5-yl 4,4,6-trimethyl-5,6-dihydro- i-propyl 1,3(4H)-oxazin-2-yl 2,4-(Me)₂Thiazol-5-yl 4,4,6-trimethyl-5,6-dihydro- cyclopropyl 1,3(4H)-oxazin-2-yl 2,4-(Me)₂Thiazol-5-yl 4,4,6-trimethyl-5,6-dihydro- CF₃ 1,3(4H)-oxazin-2-yl 2,4-(Me)₂Thiazol-5-yl 2-oxazolidinon-3-yl H 2,4-(Me)₂Thiazol-5-yl 2-oxazolidinon-3-yl methyl 2,4-(Me)₂Thiazol-5-yl 2-oxazolidinon-3-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 2-oxazolidinon-3-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-oxazolidinon-3-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 2-pyrrolidinon-1-yl methyl 2,4-(Me)₂Thiazol-5-yl 2-pyrrolidinon-1-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 2-pyrrolidinon-1-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-pyrrolidinon-1-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 3-methylisoxazol-5-yl methyl 2,4-(Me)₂Thiazol-5-yl 3-methylisoxazol-5-yl i-propyl 2,4-(Me)₂Thiazol-5-yl 3-methylisoxazol-5-yl cyclopropyl 2,4-(Me)₂Thiazol-5-yl 3-methylisoxazol-5-yl CF₃ 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-SO₂MePh H 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-SO₂MePh methyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-SO₂MePh i-propyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-SO₂MePh cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-SO₂MePh CF₃ 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-SO₂MePh H 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-SO₂MePh methyl 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-SO₂MePh i-propyl 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-SO₂MePh cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-SO₂MePh CF₃ 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-CF₃Ph H 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-CF₃Ph methyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-CF₃Ph i-propyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-CF₃Ph cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-CF₃Ph CF₃ 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-ClPh H 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-ClPh methyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-ClPh i-propyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-ClPh cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-NO₂-4-ClPh CF₃ 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-NO₂Ph H 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-NO₂Ph methyl 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-NO₂Ph i-propyl 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-NO₂Ph cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-Cl-4-NO₂Ph CF₃ 2,4-(Me)₂Thiazol-5-yl 2,4-(NO₂)₂Ph H 2,4-(Me)₂Thiazol-5-yl 2,4-(NO₂)₂Ph methyl 2,4-(Me)₂Thiazol-5-yl 2,4-(NO₂)₂Ph i-propyl 2,4-(Me)₂Thiazol-5-yl 2,4-(NO₂)₂Ph cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2,4-(NO₂)₂Ph CF₃ 2,4-(Me)₂Thiazol-5-yl 4-F-3-NO₂Ph H 2,4-(Me)₂Thiazol-5-yl 4-F-3-NO₂Ph methyl 2,4-(Me)₂Thiazol-5-yl 4-F-3-NO₂Ph i-propyl 2,4-(Me)₂Thiazol-5-yl 4-F-3-NO₂Ph cyclopropyl 2,4-(Me)₂Thiazol-5-yl 4-F-3-NO₂Ph CF₃ 2,4-(Me)₂Thiazol-5-yl 3,5-(CF₃)₂Ph H 2,4-(Me)₂Thiazol-5-yl 3,5-(CF₃)₂Ph methyl 2,4-(Me)₂Thiazol-5-yl 3,5-(CF₃)₂Ph i-propyl 2,4-(Me)₂Thiazol-5-yl 3,5-(CF₃)₂Ph cyclopropyl 2,4-(Me)₂Thiazol-5-yl 3,5-(CF₃)₂Ph CF₃ 2,4-(Me)₂Thiazol-5-yl 2-SO₂Me-4-CF₃Ph H 2,4-(Me)₂Thiazol-5-yl 2-SO₂Me-4-CF₃Ph methyl 2,4-(Me)₂Thiazol-5-yl 2-SO₂Me-4-CF₃Ph i-propyl 2,4-(Me)₂Thiazol-5-yl 2-SO₂Me-4-CF₃Ph cyclopropyl 2,4-(Me)₂Thiazol-5-yl 2-SO₂Me-4-CF₃Ph CF₃ 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-5-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-5-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-5-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-5-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-5-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-oxadiazol-5-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-oxadiazol-5-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-oxadiazol-5-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-oxadiazol-5-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-oxadiazol-5-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- H dihydroisoxazol-3-yl)Ph oxadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- methyl dihydroisoxazol-3-yl)Ph oxadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- i-propyl dihydroisoxazol-3-yl)Ph oxadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- cyclopropyl dihydroisoxazol-3-yl)Ph oxadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- CF₃ dihydroisoxazol-3-yl)Ph oxadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-oxadiazol-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-oxadiazol-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-oxadiazol-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-oxadiazol-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-oxadiazol-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-oxadiazol-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- H dihydroisoxazol-3-yl)Ph oxadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- methyl dihydroisoxazol-3-yl)Ph oxadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- i-propyl dihydroisoxazol-3-yl)Ph oxadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- cyclopropyl dihydroisoxazol-3-yl)Ph oxadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- CF₃ dihydroisoxazol-3-yl)Ph oxadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-chloro-1,2,4-oxadiazol-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-chloro-1,2,4-oxadiazol-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-chloro-1,2,4-oxadiazol-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-chloro-1,2,4-oxadiazol-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-chloro-1,2,4-oxadiazol-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-oxadiazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-oxadiazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-oxadiazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-oxadiazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-oxadiazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- H dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- methyl dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- i-propyl dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- cyclopropyl dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- CF₃ dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-oxadiazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-oxadiazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-oxadiazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-oxadiazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-oxadiazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,3,4- H dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,3,4- methyl dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,3,4- i-propyl dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,3,4- cyclopropyl dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,3,4- CF₃ dihydroisoxazol-3-yl)Ph oxadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-4-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-4-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-4-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-4-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-4-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyl-1,2,3-triazol-4-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyl-1,2,3-triazol-4-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyl-1,2,3-triazol-4-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyl-1,2,3-triazol-4-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyl-1,2,3-triazol-4-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyl-1,2,3-triazol-4-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyl-1,2,3-triazol-4-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyl-1,2,3-triazol-4-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyl-1,2,3-triazol-4-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyl-1,2,3-triazol-4-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-1-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-1-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-1-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-1-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-1-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,3-triazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-triazol-1-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-triazol-1-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-triazol-1-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-triazol-1-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-triazol-1-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-1-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-1-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-1-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-1-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-1-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-4-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-4-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-4-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-4-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- imidazol-4-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- thiazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- thiazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- thiazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- thiazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- thiazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-methylthiazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-methylthiazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-methylthiazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-methylthiazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-methylthiazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- oxazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- oxazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- oxazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- oxazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- oxazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,5-dimethyloxazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,5-dimethyloxazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,5-dimethyloxazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,5-dimethyloxazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,5-dimethyloxazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolin-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,4-dimethyl-2-oxazolin-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,4-dimethyl-2-oxazolin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,4-dimethyl-2-oxazolin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,4-dimethyl-2-oxazolin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,4-dimethyl-2-oxazolin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-5-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-5-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-5-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-5-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-5-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-thiadiazol-5-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-thiadiazol-5-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-thiadiazol-5-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-thiadiazol-5-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methyl-1,2,4-thiadiazol-5-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- H dihydroisoxazol-3-yl)Ph thiadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- methyl dihydroisoxazol-3-yl)Ph thiadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- i-propyl dihydroisoxazol-3-yl)Ph thiadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- cyclopropyl dihydroisoxazol-3-yl)Ph thiadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 3-trifluoromethyl-1,2,4- CF₃ dihydroisoxazol-3-yl)Ph thiadiazol-5-yl 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,2,4-thiadiazol-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-thiadiazol-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-thiadiazol-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-thiadiazol-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-thiadiazol-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,2,4-thiadiazol-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- H dihydroisoxazol-3-yl)Ph thiadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- methyl dihydroisoxazol-3-yl)Ph thiadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- i-propyl dihydroisoxazol-3-yl)Ph thiadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- cyclopropyl dihydroisoxazol-3-yl)Ph thiadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethyl-1,2,4- CF₃ dihydroisoxazol-3-yl)Ph thiadiazol-3-yl 2-Me-4-SO₂Me-3-(4,5- 1,3,4-thiadiazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-thiadiazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-thiadiazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-thiadiazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1,3,4-thiadiazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- H dihydroisoxazol-3-yl)Ph thiadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- methyl dihydroisoxazol-3-yl)Ph thiadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- i-propyl dihydroisoxazol-3-yl)Ph thiadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- cyclopropyl dihydroisoxazol-3-yl)Ph thiadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methylsulfonyl-1,3,4- CF₃ dihydroisoxazol-3-yl)Ph thiadiazol-2-yl 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-thiadiazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-thiadiazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-thiadiazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-thiadiazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyl-1,3,4-thiadiazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzoxazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzoxazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzoxazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzoxazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzoxazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-methylbenzoxazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-methylbenzoxazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-methylbenzoxazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-methylbenzoxazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-methylbenzoxazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzothiazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzothiazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzothiazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzothiazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- benzothiazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-1-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-1-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-1-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-1-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-1-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazol-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methylpyrazol-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methylpyrazol-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methylpyrazol-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methylpyrazol-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methylpyrazol-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-1-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-1-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-1-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-1-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-1-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-1-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-1-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-1-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-1-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-1-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- tetrazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-methyltetrazol-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyltetrazol-5-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyltetrazol-5-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyltetrazol-5-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyltetrazol-5-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 1-methyltetrazol-5-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyltetrazol-5-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyltetrazol-5-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyltetrazol-5-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyltetrazol-5-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-methyltetrazol-5-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-4-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-4-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-4-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-4-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-4-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridin-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-nitropyridin-4-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-nitropyridin-4-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-nitropyridin-4-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-nitropyridin-4-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-nitropyridin-4-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-cyanopyridin-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-cyanopyridin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-cyanopyridin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-cyanopyridin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-cyanopyridin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethylpyridin-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethylpyridin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethylpyridin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethylpyridin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 5-trifluoromethylpyridin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-2-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-4-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-4-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-4-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-4-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrimidin-4-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-chloropyrimidin-4-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-chloropyrimidin-4-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-chloropyrimidin-4-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-chloropyrimidin-4-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridazin-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridazin-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridazin-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridazin-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyridazin-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-chloropyridazin-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-chloropyridazin-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-chloropyridazin-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 6-chloropyridazin-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- pyrazin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- triazin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- triazin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- triazin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- triazin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- quinolin-2-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- quinolin-2-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- quinolin-2-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- quinolin-2-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4,4,6-trimethyl-5,6-dihydro- H dihydroisoxazol-3-yl)Ph 1,3(4H)-oxazin-2-yl 2-Me-4-SO₂Me-3-(4,5- 4,4,6-trimethyl-5,6-dihydro- methyl dihydroisoxazol-3-yl)Ph 1,3(4H)-oxazin-2-yl 2-Me-4-SO₂Me-3-(4,5- 4,4,6-trimethyl-5,6-dihydro- i-propyl dihydroisoxazol-3-yl)Ph 1,3(4H)-oxazin-2-yl 2-Me-4-SO₂Me-3-(4,5- 4,4,6-trimethyl-5,6-dihydro- cyclopropyl dihydroisoxazol-3-yl)Ph 1,3(4H)-oxazin-2-yl 2-Me-4-SO₂Me-3-(4,5- 4,4,6-trimethyl-5,6-dihydro- CF₃ dihydroisoxazol-3-yl)Ph 1,3(4H)-oxazin-2-yl 2-Me-4-SO₂Me-3-(4,5- 2-oxazolidinon-3-yl H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolidinon-3-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolidinon-3-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolidinon-3-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-oxazolidinon-3-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-pyrrolidinon-1-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-pyrrolidinon-1-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-pyrrolidinon-1-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-pyrrolidinon-1-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methylisoxazol-5-yl methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methylisoxazol-5-yl i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methylisoxazol-5-yl cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3-methylisoxazol-5-yl CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-SO₂MePh H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-SO₂MePh methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-SO₂MePh i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-SO₂MePh cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-SO₂MePh CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-SO₂MePh H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-SO₂MePh methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-SO₂MePh i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-SO₂MePh cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-SO₂MePh CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-CF₃Ph H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-CF₃Ph methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-CF₃Ph i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-CF₃Ph cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-CF₃Ph CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-ClPh H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-ClPh methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-ClPh i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-ClPh cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-NO₂-4-ClPh CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-NO₂Ph H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-NO₂Ph methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-NO₂Ph i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-NO₂Ph cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-Cl-4-NO₂Ph CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2,4-(NO₂)₂Ph H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2,4-(NO₂)₂Ph methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2,4-(NO₂)₂Ph i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2,4-(NO₂)₂Ph cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2,4-(NO₂)₂Ph CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-F-3-NO₂Ph H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-F-3-NO₂Ph methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-F-3-NO₂Ph i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-F-3-NO₂Ph cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 4-F-3-NO₂Ph CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3,5-(CF₃)₂Ph H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3,5-(CF₃)₂Ph methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3,5-(CF₃)₂Ph i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3,5-(CF₃)₂Ph cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 3,5-(CF₃)₂Ph CF₃ dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-SO₂Me-4-CF₃Ph H dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-SO₂Me-4-CF₃Ph methyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-SO₂Me-4-CF₃Ph i-propyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-SO₂Me-4-CF₃Ph cyclopropyl dihydroisoxazol-3-yl)Ph 2-Me-4-SO₂Me-3-(4,5- 2-SO₂Me-4-CF₃Ph CF₃ dihydroisoxazol-3-yl)Ph 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-5-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-5-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-5-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-5-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-5-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-oxadiazol-5-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-oxadiazol-5-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-oxadiazol-5-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-oxadiazol-5-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-oxadiazol-5-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- H dihydro-1,4-benzo- oxadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- methyl dihydro-1,4-benzo- oxadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- i-propyl dihydro-1,4-benzo- oxadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- cyclopropyl dihydro-1,4-benzo- oxadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- CF₃ dihydro-1,4-benzo- oxadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-oxadiazol-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-oxadiazol-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-oxadiazol-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-oxadiazol-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-oxadiazol-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-oxadiazol-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- H dihydro-1,4-benzo- oxadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- methyl dihydro-1,4-benzo- oxadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- i-propyl dihydro-1,4-benzo- oxadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- cyclopropyl dihydro-1,4-benzo- oxadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- CF₃ dihydro-1,4-benzo- oxadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-chloro-1,2,4-oxadiazol-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-chloro-1,2,4-oxadiazol-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-chloro-1,2,4-oxadiazol-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-chloro-1,2,4-oxadiazol-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-chloro-1,2,4-oxadiazol-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-oxadiazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-oxadiazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-oxadiazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-oxadiazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-oxadiazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- H dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- methyl dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- i-propyl dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- cyclopropyl dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- CF₃ dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-oxadiazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-oxadiazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-oxadiazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-oxadiazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-oxadiazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,3,4- H dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,3,4- methyl dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,3,4- i-propyl dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,3,4- cyclopropyl dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,3,4- CF₃ dihydro-1,4-benzo- oxadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-4-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-4-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-4-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-4-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-4-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyl-1,2,3-triazol-4-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyl-1,2,3-triazol-4-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyl-1,2,3-triazol-4-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyl-1,2,3-triazol-4-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyl-1,2,3-triazol-4-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyl-1,2,3-triazol-4-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyl-1,2,3-triazol-4-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyl-1,2,3-triazol-4-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyl-1,2,3-triazol-4-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyl-1,2,3-triazol-4-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-1-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-1-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-1-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-1-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-1-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,3-triazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-triazol-1-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-triazol-1-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-triazol-1-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-triazol-1-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-triazol-1-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-1-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-1-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-1-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-1-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-1-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-4-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-4-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-4-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-4-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- imidazol-4-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- thiazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- thiazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- thiazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- thiazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- thiazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-methylthiazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-methylthiazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-methylthiazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-methylthiazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-methylthiazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- oxazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- oxazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- oxazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- oxazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- oxazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,5-dimethyloxazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,5-dimethyloxazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,5-dimethyloxazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,5-dimethyloxazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,5-dimethyloxazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolin-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4-dimethyl-2-oxazolin-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4-dimethyl-2-oxazolin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4-dimethyl-2-oxazolin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4-dimethyl-2-oxazolin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4-dimethyl-2-oxazolin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-5-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-5-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-5-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-5-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-5-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-thiadiazol-5-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-thiadiazol-5-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-thiadiazol-5-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-thiadiazol-5-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methyl-1,2,4-thiadiazol-5-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- H dihydro-1,4-benzo- thiadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- methyl dihydro-1,4-benzo- thiadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- i-propyl dihydro-1,4-benzo- thiadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- cyclopropyl dihydro-1,4-benzo- thiadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-trifluoromethyl-1,2,4- CF₃ dihydro-1,4-benzo- thiadiazol-5-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,2,4-thiadiazol-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-thiadiazol-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-thiadiazol-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-thiadiazol-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-thiadiazol-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,2,4-thiadiazol-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- H dihydro-1,4-benzo- thiadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- methyl dihydro-1,4-benzo- thiadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- i-propyl dihydro-1,4-benzo- thiadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- cyclopropyl dihydro-1,4-benzo- thiadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethyl-1,2,4- CF₃ dihydro-1,4-benzo- thiadiazol-3-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-thiadiazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-thiadiazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-thiadiazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-thiadiazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1,3,4-thiadiazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- H dihydro-1,4-benzo- thiadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- methyl dihydro-1,4-benzo- thiadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- i-propyl dihydro-1,4-benzo- thiadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- cyclopropyl dihydro-1,4-benzo- thiadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methylsulfonyl-1,3,4- CF₃ dihydro-1,4-benzo- thiadiazol-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-thiadiazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-thiadiazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-thiadiazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-thiadiazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyl-1,3,4-thiadiazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzoxazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzoxazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzoxazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzoxazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzoxazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-methylbenzoxazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-methylbenzoxazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-methylbenzoxazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-methylbenzoxazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-methylbenzoxazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzothiazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzothiazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzothiazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzothiazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- benzothiazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-1-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-1-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-1-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-1-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-1-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazol-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methylpyrazol-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methylpyrazol-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methylpyrazol-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methylpyrazol-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methylpyrazol-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-1-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-1-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-1-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-1-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-1-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-1-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-1-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-1-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-1-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-1-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- tetrazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-methyltetrazol-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyltetrazol-5-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyltetrazol-5-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyltetrazol-5-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyltetrazol-5-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 1-methyltetrazol-5-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyltetrazol-5-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyltetrazol-5-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyltetrazol-5-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyltetrazol-5-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-methyltetrazol-5-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-4-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-4-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-4-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-4-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-4-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridin-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-nitropyridin-4-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-nitropyridin-4-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-nitropyridin-4-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-nitropyridin-4-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-nitropyridin-4-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-cyanopyridin-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-cyanopyridin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-cyanopyridin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-cyanopyridin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-cyanopyridin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethylpyridin-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethylpyridin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethylpyridin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethylpyridin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 5-trifluoromethylpyridin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-2-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-4-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-4-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-4-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-4-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrimidin-4-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-chloropyrimidin-4-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-chloropyrimidin-4-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-chloropyrimidin-4-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-chloropyrimidin-4-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridazin-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridazin-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridazin-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridazin-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyridazin-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-chloropyridazin-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-chloropyridazin-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-chloropyridazin-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 6-chloropyridazin-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- pyrazin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- triazin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- triazin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- triazin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- triazin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- quinolin-2-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- quinolin-2-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- quinolin-2-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- quinolin-2-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4,6-trimethyl-5,6-dihydro- H dihydro-1,4-benzo- 1,3(4H)-oxazin-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4,6-trimethyl-5,6-dihydro- methyl dihydro-1,4-benzo- 1,3(4H)-oxazin-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4,6-trimethyl-5,6-dihydro- i-propyl dihydro-1,4-benzo- 1,3(4H)-oxazin-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4,6-trimethyl-5,6-dihydro- cyclopropyl dihydro-1,4-benzo- 1,3(4H)-oxazin-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4,4,6-trimethyl-5,6-dihydro- CF₃ dihydro-1,4-benzo- 1,3(4H)-oxazin-2-yl xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolidinon-3-yl H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolidinon-3-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolidinon-3-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolidinon-3-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-oxazolidinon-3-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-pyrrolidinon-1-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-pyrrolidinon-1-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-pyrrolidinon-1-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-pyrrolidinon-1-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methylisoxazol-5-yl methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methylisoxazol-5-yl i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methylisoxazol-5-yl cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3-methylisoxazol-5-yl CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-SO₂MePh H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-SO₂MePh methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-SO₂MePh i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-SO₂MePh cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-SO₂MePh CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-SO₂MePh H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-SO₂MePh methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-SO₂MePh i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-SO₂MePh cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-SO₂MePh CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-CF₃Ph H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-CF₃Ph methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-CF₃Ph i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-CF₃Ph cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-CF₃Ph CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-ClPh H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-ClPh methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-ClPh i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-ClPh cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-NO₂-4-ClPh CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-NO₂Ph H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-NO₂Ph methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-NO₂Ph i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-NO₂Ph cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-Cl-4-NO₂Ph CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2,4-(NO₂)₂Ph H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2,4-(NO₂)₂Ph methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2,4-(NO₂)₂Ph i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2,4-(NO₂)₂Ph cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2,4-(NO₂)₂Ph CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-F-3-NO₂Ph H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-F-3-NO₂Ph methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-F-3-NO₂Ph i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-F-3-NO₂Ph cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 4-F-3-NO₂Ph CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3,5-(CF₃)₂Ph H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3,5-(CF₃)₂Ph methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3,5-(CF₃)₂Ph i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3,5-(CF₃)₂Ph cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 3,5-(CF₃)₂Ph CF₃ dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-SO₂Me-4-CF₃Ph H dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-SO₂Me-4-CF₃Ph methyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-SO₂Me-4-CF₃Ph i-propyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-SO₂Me-4-CF₃Ph cyclopropyl dihydro-1,4-benzo- xathiin-7-yl 4,4-dioxide-8-Me-2,3- 2-SO₂Me-4-CF₃Ph CF₃ dihydro-1,4-benzo- xathiin-7-yl 2-Cl-4-SO₂MePh 2-trifluoromethyl-1,3,4- cyclopropyl thiadiazol-5-yl 2-Cl-4-SO₂MePh 1,1-dioxido-3-oxo-1,2- cyclopropyl benzisothiazol-2(3H)-yl 4-Cl—Ph 2-t-butyl-1,3,4-oxadiazol-5-yl CF3 2-Me-6-CF₃Pyridin-3-yl 2-methyltetrazol-5-yl cyclopropyl 2-[(2-methoxyethoxy) 2-methyltetrazol-5-yl cyclopropyl methyl]-6-CF₃Pyridin- 3-yl 2-Cl-4-SO₂MePh 2,5-dioxopyrrolidin-1-yl cyclopropyl 2-Cl-4-SO₂MePh 2-oxopyridin-1(2H)-yl cyclopropyl 2-Cl-4-SO₂MePh 2-oxoquinolin-1(2H)-yl cyclopropyl 2-Cl-4-SO₂MePh 1,2-benzisoxazol-3-yl cyclopropyl 2-Cl-4-SO₂MePh 2-oxo-1,3-benzoxazol-3(2H)-yl cyclopropyl 2-Cl-4-SO₂MePh 3-oxo-2,3-dihydro-4H-1,4- cyclopropyl benzoxazin-4-yl 2-Cl-4-SO₂MePh 2-oxopyrimidin-1(2H)-yl cyclopropyl 2-Cl-4-SO₂MePh 1H-1,2,3-benzotriazol-1-yl cyclopropyl 2-NO₂-4-SO₂MePh 2,5-dioxopyrrolidin-1-yl cyclopropyl 2-NO₂-4-SO₂MePh 2-oxopyridin-1(2H)-yl cyclopropyl 2-NO₂-4-SO₂MePh 2-oxoquinolin-1(2H)-yl cyclopropyl 2-NO₂-4-SO₂MePh 1,2-benzisoxazol-3-yl cyclopropyl 2-NO₂-4-SO₂MePh 2-oxo-1,3-benzoxazol-3(2H)-yl cyclopropyl 2-NO₂-4-SO₂MePh 3-oxo-2,3-dihydro-4H-1,4- cyclopropyl benzoxazin-4-yl 2-NO₂-4-SO₂MePh 2-oxopyrimidin-1(2H)-yl cyclopropyl 2-NO₂-4-SO₂MePh 1H-1,2,3-benzotriazol-1-yl cyclopropyl

The compounds having general formula (I) can be applied in the pharmaceutical field, for example in the treatment of the hereditary disease known as tyrosinemia type 1 (HT-1).

A further object of the present invention relates to processes for the preparation of compounds having general formula (I).

In particular, the compounds having general formula (I) can be prepared by the reaction of a carbonyl compound having general formula (II) with a compound having general formula (III) according to reaction scheme 1.

In the general formulae indicated in this reaction scheme:

-   A, B and R have the meanings previously defined; -   L₁ represents a suitable leaving group such as, for example, a     halogen atom, a CN group, an imidazol-1-yl group, an R_(L)O— group     wherein R_(L) represents a C₁-C₄ alkyl group or a phenyl group     optionally substituted, or it represents an R_(L1)COO— group wherein     R_(L1) represents a hydrogen atom, a C₁-C₄ alkyl or haloalkyl group,     a phenyl group optionally substituted or an A group.

The reaction between the compounds having general formula (II) and the compounds having general formula (III) is preferably carried out in the presence of an inert organic solvent and in the presence of an organic or inorganic base, at a temperature ranging from −80° C. to the boiling point of the reaction mixture. The reaction can also be carried out in two distinct phases. In the latter case, in the first phase, the compounds having general formula (II) are reacted with a base. The intermediate obtained is reacted, in the subsequent phase, with an acylating compound.

Examples of solvents which can be used for the above reaction comprise aromatic hydrocarbons (benzene, toluene, xylene, chlorobenzene, etc.), ethers (diethyl ether, diisopropyl ether, dimethoxyethane, dioxane, tetrahydrofuran, etc.), aprotic dipolar solvents (dimethylformamide, dimethylacetamide, hexamethylphosphoramide, N-methylpyrrolidone, etc.).

Inorganic bases which can be used for the purpose are, for example, sodium and potassium hydrides, hydroxides and carbonates, sodium amide.

Organic bases which can be used for the purpose are, for example, sodium, potassium and magnesium alcoholates, phenyllithium, butyllithium, lithium diisopropylamide, triethylamine, pyridine, 4-N,N-dimethylaminopyridine, N,N-dimethylaniline, N-methyl piperidine, lutidine, diazabicyclooctane (DABCO), diazabicyclononene (DBN), diazabicycloundecene (DBU).

The compounds having general formula (I) can also be prepared by the reaction of a carbonyl compound having general formula (IV) with a compound having general formula (V) according to reaction, scheme 2.

In the general formulae indicated in this reaction scheme:.

-   A, B and R have the meanings previously defined; -   L₂ represents a suitable leaving group such as, for example, a     halogen atom, a CN group, an imidazol-1-yl group, an R_(L)O— group     wherein R_(L) represents a C₁-C₄ alkyl group or a phenyl group     optionally substituted, or it represents an R_(L1)COO— group wherein     R_(L1) represents a hydrogen atom, a C₁-C₄ alkyl or haloalkyl group,     a phenyl group optionally substituted or an R group.

The reaction between the compounds having general formula (IV) and the compounds having general formula (V) is preferably carried out in the presence of an inert organic solvent and in the presence of an organic or preferably inorganic base, at a temperature ranging from −80° C. to the boiling point of the reaction mixture. The reaction can also be carried out in two distinct phases. In the latter case, in the first phase, the compounds having general formula (IV) are reacted with a base. The intermediate obtained is reacted, in the subsequent phase, with an acylating compound.

Examples of solvents which can be used for the above reaction comprise aromatic hydrocarbons (benzene, toluene, xylene, chlorobenzene, etc.), ethers (diethyl ether, diisopropyl ether, dimethoxyethane, dioxane, tetrahydrofuran, etc.), aprotic dipolar solvents (dimethylformamide, dimethylacetamide, hexamethylphosphoramide, N-methylpyrrolidone, etc.).

Inorganic bases which can be used for the purpose are, for example, sodium and potassium hydrides, hydroxides and carbonates, sodium amide.

Organic bases which can be used for the purpose are, for example, sodium, potassium and magnesium alcoholates, phenyllithium, butyllithium, lithium diisopropylamide, triethylamine, pyridine, 4-N,N-dimethylaminopyridine, N,N-dimethylaniline, N-methyl piperidine, lutidine, diazabicyclooctane (DABCO), diazabicyclononene (DBN), diazabicycloundecene (DBU).

The compounds having general formula (I) can also be prepared by the reaction of a 1,3-dicarbonyl compound having general formula (VI) with a compound having general formula (VII) according to reaction scheme 3.

In the general formulae indicated in this reaction scheme:

-   A, B and R have the meanings previously defined; -   X represents a halogen atom, an R_(L2)SO₂O— group, wherein R_(L2)     represents a C₁-C₄ alkyl or haloalkyl group, a phenyl group     optionally substituted by C₁-C₄ alkyl groups, or it represents an     R_(L3)SO₂— group, wherein R_(L3) represents a C₁-C₄ alkyl or     haloalkyl group.

The reaction between the compounds having general formula (VI) and the compounds having general formula (VII) is preferably carried out in the presence of one or more inert organic solvents and in the presence of an organic or inorganic base, at a temperature ranging from −80° C. to the boiling point of the reaction mixture.

Organic solvents which can be used for the purpose are, for example, aromatic hydrocarbons (benzene, toluene, xylene, chlorobenzene, etc.), ethers (diethyl ether, diisopropyl ether, dimethoxyethane, dioxane, tetrahydrofuran, etc.), alcohols and glycols (methanol, ethanol, methyl cellosolve, ethylene glycol, etc.), ketones (acetone, methyl ethyl ketone, methyl propyl ketone, methyl isobutyl ketone, etc.), nitriles (acetonitrile, benzonitrile, etc.), aprotic dipolar solvents (dimethylformamide, dimethylacetamide, hexamethylphosphoramide, dimethylsulfoxide, sulfolane, N-methylpyrrolidone, etc.).

Organic bases which can be used for the purpose are, for example, sodium, potassium and magnesium alcoholates, phenyllithium, butyllithium, lithium diisopropylamide, triethylamine, pyridine, 4-N,N-dimethylaminopyridine, N,N-dimethylaniline, N-methyl piperidine, lutidine, diazabicyclooctane (DABCO), diazabicyclononene (DBN), diazabicycloundecene (DBU).

Inorganic bases which can be used for the purpose are, for example, sodium or potassium hydrides, hydroxides and carbonates, sodium amide.

The reaction can also be carried out using suitable catalysts based on transition metals, such as, for example, Cu and Pd.

Examples of these reactions are described in Chem. Pharm. Bull. (1987), vol. 35, pages 4972-4976 and J. Chem. Soc., Perkin 1 (1976), vol. 6, pages 592-594.

The 1,3-dicarbonyl compounds having general formula (VI) can be prepared by the acylation of ketones according to what is described, for example, in Organic Reaction (1954), vol. 8, pages 59-196, or in Tetrahedron Letters (2002), vol. 43, pages 2945-2948.

The compounds having general formula (II) can be prepared by the reaction of a compound having general formula (VIII) with an acylating compound having general formula (V) according to reaction scheme 4.

In the general formulae indicated in this reaction scheme:

-   B and R have the meanings previously defined; -   L₂ represents a suitable leaving group such as, for example, a     halogen atom, a CN group, an imidazol-1-yl group, an R_(L)O— group     wherein R_(L) represents a C₁-C₄ alkyl group or a phenyl group     optionally substituted, or it represents an R_(L1)COO— group wherein     R_(L1) represents a hydrogen atom, a C₁-C₄ alkyl or haloalkyl group,     a phenyl group optionally substituted or an R group.

The reaction between the compounds having general formula (VIII) and the compounds having general formula (V) is preferably carried out in the presence of an inert organic solvent and in the presence of an organic or preferably inorganic base, at a temperature ranging from −80° C. to the boiling point of the reaction mixture. The reaction can also be carried out in two distinct phases. In the latter case, in the first phase, the compounds having general formula (VIII) are reacted with a base. The intermediate obtained is reacted, in the subsequent phase, with an acylating compound.

Examples of solvents which can be used for the above reaction comprise aromatic hydrocarbons (benzene, toluene, xylene, chlorobenzene, etc.), ethers (diethyl ether, diisopropyl ether, dimethoxyethane, dioxane, tetrahydrofuran, etc.), aprotic dipolar solvents (dimethylformamide, dimethylacetamide, hexamethylphosphoramide, N-methylpyrrolidone, etc.).

Inorganic bases which can be used for the purpose are, for example, sodium and potassium hydrides, hydroxides and carbonates, sodium amide.

Organic bases which can be used for the purpose are, for example, sodium, potassium and magnesium alcoholates, phenyllithium, butyllithium, lithium diisopropylamide, triethylamine, pyridine, 4-N,N-dimethylaminopyridine, N,N-dimethylaniline, N-methyl piperidine, lutidine, diazabicyclooctane (DABCO), diazabicyclononene (DBN), diazabicycloundecene (DBU).

The compounds having general formula (IV) can be prepared by the reaction of a compound having general formula (VIII) with an acylating compound having general formula (III) according to reaction scheme 5.

In the general formulae indicated in this reaction scheme:

-   B and A have the meanings previously defined; -   L₁ represents a suitable leaving group such as, for example, a     halogen atom, a CN group, an imidazol-1-yl group, an R_(L)O— group     wherein R_(L) represents a C₁-C₄ alkyl group or a phenyl group     optionally substituted, or it represents an R_(L1)COO— group wherein     R_(L1) represents a hydrogen atom, a C₁-C₄ alkyl or haloalkyl group,     a phenyl group optionally substituted or an A group.

The reaction between the compounds having general formula (VIII) and the compounds having general formula (III) is preferably carried out in the presence of an inert organic solvent and in the presence of an organic or inorganic base, at a temperature ranging from −80° C. to the boiling point of the reaction mixture. The reaction can also be carried out in two distinct phases. In the latter case, in the first phase, the compounds having general formula (VIII) are reacted with a base. The intermediate obtained is reacted, in the subsequent phase, with an acylating compound.

Examples of solvents which can be used for the above reaction comprise aromatic hydrocarbons (benzene, toluene, xylene, chlorobenzene, etc.), ethers (diethyl ether, diisopropyl ether, dimethoxyethane, dioxane, tetrahydrofuran, etc.), aprotic dipolar solvents (dimethylformamide, dimethylacetamide, hexamethylphosphoramide, N-methylpyrrolidone, etc.).

Inorganic bases which can be used for the purpose are, for example, sodium and potassium hydrides, hydroxides and carbonates, sodium amide.

Organic bases which can be used for the purpose are, for example, sodium, potassium and magnesium alcoholates, phenyllithium, butyllithium, lithium diisopropylamide, triethylamine, pyridine, 4-N,N-dimethylaminopyridine, N,N-dimethylaniline, N-methyl piperidine, lutidine, diazabicyclooctane (DABCO), diazabicyclononene (DBN), diazabicycloundecene (DBU).

The compounds having general formula (IV) can also be prepared by the reaction of a compound having general formula (IX) with an acylating compound having general formula (III) in the presence of a base. The reaction provides intermediate compounds having general formula (X) which then undergo a hydrolysis and decarboxylation process according to reaction scheme 6.

In the general formulae indicated in this reaction scheme:

-   B and A have the meanings previously defined; -   L₁ represents a suitable leaving group such as, for example, a     halogen atom, a CN group, an imidazol-1-yl group, an R_(L)O— group     wherein R_(L) represents a C₁-C₄ alkyl group or a phenyl group     optionally substituted, or it represents an R_(L1)COO— group wherein     R_(L1) represents a hydrogen atom, a C₁-C₄ alkyl or haloalkyl group,     a phenyl group optionally substituted or one of the A groups. -   Rv represents a C₁-C₅ alkyl or haloalkyl group, an arylalkyl or aryl     group. -   The compounds having general formula (II) can also be prepared by     the reaction of a compound having general formula (IX) with an     acylating compound having general formula (V) in the presence of a     base. The reaction provides intermediate compounds having general     formula (XI) which then undergo a hydrolysis and decarboxylation     process according to reaction scheme 7.

In the general formulae indicated in this reaction scheme:

-   B and R have the meanings previously defined; -   L₂ represents a suitable leaving group such as, for example, a     halogen atom, a CN group, an imidazol-1-yl group, an R_(L)O— group     wherein R_(L) represents a C₁-C₄ alkyl group or a phenyl group     optionally substituted, or it represents an R_(L1)COO— group wherein     R_(L1) represents a hydrogen atom, a C₁-C₄ alkyl or haloalkyl group,     a phenyl group optionally substituted or one of the R groups. -   Rv represents a C₁-C₅ alkyl or haloalkyl group, an arylalkyl or aryl     group.

The reactions indicated in reaction schemes 6 and 7 can be carried out, for example, according to the methods described in J. Am. Chem. Soc. (1950), vol. 72, pages 1352-1356 and in J. Am. Chem. Soc. (1987), vol. 109, pages 4717-4718.

The compounds having general formula (II) wherein R has the meanings previously defined and B represents a 1,2,4-oxadiazol-5-yl, compounds (IIa), can be prepared, for example, starting from compounds having general formula (XII) by reaction with an amidoxime having general formula (XIII) according to reaction scheme 8.

The above reaction can be carried out according to the method described for example in Bull. Soc. Chim. Belges (1949), vol. 58, pages 58-65.

The compounds having general formula (II) wherein R has the meanings previously defined and B represents tetrazol-5-yl (D=tetrazole, R_(x)=H), compounds (IIb), can be prepared, for example, starting from compounds having general formula (XIV) by transforming the cyano group into tetrazole, for example by heating with trimethylsilylazide, in toluene, catalyzed by dibutyltin oxide, according to what is described in J. Org. Chem. (1933), vol. 58, pages 4139-4141, or by heating with sodium azide in water with the catalysis of ZnBr₂, as described in J. Org. Chem. (2001), vol. 66, pages 7945-7950.

The above transformation is indicated in reaction scheme 9.

The intermediates having general formulae (III), (V), (VII), (VIII), (IX), (XII), (XIII) and (XIV), when not already known as such, can be easily prepared according to methods known in organic chemistry practice.

In some cases, the compounds having general formula (I) can be obtained in the form of two or more optic or geometric or position isomers. Compounds having general formula (I) which are isomerically pure, and also mixtures of these, possibly obtained during the preparation of the compounds having general formula (I) or deriving from an incomplete separation of the isomers themselves, in any proportion, are therefore considered as being included within the scope of the present invention.

As already mentioned, the compounds having general formula (I) have a high herbicidal activity which makes them suitable for use in the agrarian field in the defense of useful crops from weeds.

In particular, the compounds, object of the present invention, are effective in the control, in both pre-emergence and post-emergence, of numerous monocotyledon and dicotyledon weeds. At the same time, these compounds show compatibility or the absence of toxic effects with respect to useful crops in pre- and/or post-emergence treatments.

The compounds of the present invention can act as total or selective herbicides also in relation to the quantity of active principle used.

Examples of weeds which can be effectively controlled using the compounds having general formula (I) are: Abutilon theofrasti, Alisma plantago, Amaranthus spp., Amni maius, Capsella bursa pastoris, Chenopodium album, Convolvulus sepium, Galium aparine, Geranium dissectum, Ipomea spp., Matricaria spp., Papaver rhoaes, Phaseolus aureus, Polygonum persicaria, Portulaca oleracea, Sida spinosa, Sinapsis arvensis, Solanum nigrum, Stellaria media, Veronica spp., Viola spp., Xanthium spp., Alopercurus myosuroides, Avena fatua, Cyperus spp., Digitaria sanguinalis, Echinocloa spp., Heleocaris avicularis, Heteranthera spp., Panicum spp., Poa spp., Scirpus spp., Sorghum spp., etc.

With the doses of use suitable for agrarian applications, many of the above compounds showed no toxic effects towards one or more important agrarian crops such as corn (Zea mays), wheat (Triticum sp.), barley (Hordeum vulgare), soybean (Glycine max), rice (Oryza sativa).

A further object of the present invention relate; to a method for controlling weeds in cultivated areas by the application of the compounds having general formula (I).

The quantity of compound to be applied for obtaining the desired effect can vary in relation to various factors such as, for example, the compound used, the crop to be preserved, the weed to be fought, the degree of infestation, the climatic conditions, the characteristics of the soil, the application method, etc.

Doses of compound ranging from 1 g to 4,000 g per hectare generally provide a sufficient control.

For use in agriculture, it is often advantageous to adopt compositions with a herbicidal activity containing, as active substance, one or more compounds having general formula (I), optionally also as a mixture of tautomers and/or isomers.

Compositions can be used in the form of dry powders, wettable powders, emulsifiable concentrates, micro-emulsions, pastes, granulates, solutions, suspensions, etc.: the selection of the type of composition depends on the specific use.

The compositions are prepared according to known methods, for example by diluting or dissolving the active substance by means of a solvent medium and/or solid diluent, possibly in the presence of surface-active agents.

Kaolin, alumina, silica, talc, bentonite, chalk, quartz, dolomite, attapulgite, montmorillonite, diatomaceous earth, cellulose, starch, etc., can be used as inert solid diluents, or carriers.

Inert liquid diluents which can be used, are water or organic solvents such as aromatic hydrocarbons (xylols, blends of alkyl benzenes, etc.), aliphatic hydrocarbons (hexane, cyclohexane, etc.) halogenated aromatic hydrocarbons (chlorobenzene, etc.), alcohols (methanol, propanol, butanol, octanol, etc.), esters (isobutyl acetate, etc.), ketones (acetone, cyclohexanone, acetophenone, isophorone, ethylamylketone etc.), or vegetable and mineral oils or mixtures thereof, etc.

Surfactants which can be used are wetting and emulsifying agents, of the non-ionic type (polyethoxylated alkyl phenols, polyethoxylated fatty alcohols, etc.), of the anionic type (alkylbenzenesulphonates, alkylsulphonates, etc.), of the cationic type (alkyl ammonium quaternary salts, etc.).

Dispersing agents can also be added (for example lignin and its salts, cellulose derivatives, alginates, etc.), stabilizers (for example antioxidants, UV absorbers, etc.).

In order to enlarge the action range of the above compositions, it is possible to add active ingredients, such as, for example, other herbicides, fungicides, insecticides, acaricides, fertilizers, etc.

Examples of other herbicides which can be added to the compositions containing one or more compounds having general formula (I), are the following: Acetochlor, acifluorfen, aclonifen, AKH-7088, alachlor, alloxydim, ametryn, amicarbazone, amidosulfuron, amitrole, anilofos, asulam, atrazine, azafenidin, azimsulfuron, aziprotryne, BAS 670 H, BAY MKH 6561, beflubutamid, benazolin, benfluralin, benfuresate, bensulfuron, bensulide, bentazone, benzfendizone, benzobicyclon, benzofenap, benzthiazuron, bifenox, bilanafos, bispyribac-sodium, bromacil, bromobutide, bromofenoxim, bromoxynil, butachlor, butafenacil, butamifos, butenachlor, butralin, butroxydim, butylate, cafenstrole, carbetamide, carfentrazone-ethyl, chlomethoxyfen, chloramben, chlorbromuron, chlorbufam, chlorflurenol, chloridazon, chlorimuron, chlornitrofen, chlorotoluron, chloroxuron, chlorpropham, chlorsulfuron, chlorthal, chlorthiamid, cinidon ethyl, cinmethylin, cinosulfuron, clethodim, clodinafop, clomazone, clomeprop, clopyralid, cloransulam-methyl, cumyluron (JC-940), cyanazine, cycloate, cyclosulfamuron, cycloxydim, cyhalofop-butyl, 2,4-D, 2,4-DB, daimuron, dalapon, desmedipham, desmetryn, dicamba, dichlobenil, dichlorprop, dichlorprop-P, diclofop, diclosulam, diethatyl, difenoxuron, difenzoquat, diflufenican, diflufenzopyr, dimefuron, dimepiperate, dimethachlor, dimethametryn, dimethenamid, dinitramine, dinosseb, dinoseb acetate, dinoterb, diphenamid, dipropetryn, diquat, dithiopyr, 1-diuron, eglinazine, endothal, EPTC, espropcarb, ethalfluralin, ethametsulfuron-methyl, ethidimuron, ethiozin (SMY 1500), ethofumesate, ethoxyfen-ethyl (HC-252), ethoxysulfuron, etobenzanid (HW 52), fenoxaprop, fenoxaprop-P, fentrazamide, fenuron, flamprop, flamprop-M, flazasulfuron, florasulam, fluazifop, fluazifop-P, fluazolate (JV 485), flucarbazone-sodium, fluchloralin, flufenacet, flufenpyr ethyl, flumetsulam, flumiclorac-pentyl, flumioxazin, flumipropin, fluometuron, fluoroglycofen, fluoronitrofen, flupoxam, fluproanate, flupyrsulfuron, flurenol, fluridone, flurochloridone, fluroxypyr, flurtamone, fluthiacet-methyl, fomesafen, foramsulfuron, fosamine, furyloxyfen, glufosinate, glyphosate, halosulfuron-methyl, haloxyfop, haloxyfop-P-methyl, hexazinone, imazamethabenz, imazamox, imazapic, imazapyr, imazaquin, imazethapyr, imazosulfuron, indanofan, iodosulfuron, ioxynil, isopropalin, isoproturon, isouron, isoxaben, isoxachlortole, isoxaflutole, isoxapyrifop, KPP-421, lactofen, lenacil, linuron, LS830556, MCPA, MCPA-thioethyl, MCPB, mecoprop, mecoprop-P, mefenacet, mesosulfuron, mesotrione, metamitron, metazachlor, methabenzthiazuron, methazole, methoprotryne, methyldymron, metobenzuron, metobromuron, metolachlor, S-metolachlor, metosulam, metoxuron, metribuzin, metsulfuron, molinate, monalide, monolinuron, naproanilide, napropamide, naptalam, NC-330, neburon, nicosulfuron, nipyraclofen, norflurazon, orbencarb, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone, oxyfluorfen, paraquat, pebulate, pendimethalin, penoxsulam, pentanochlor, pentoxazone, pethoxamid, phenmedipham, picloram, picolinafen, piperophos, pretilachlor, primisulfuron, prodiamine, profluazol, proglinazine, prometon, prometryne, propachlor, propanil, propaquizafop, propazine, propham, propisochlor, propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraflufen-ethyl, pyrazogyl (HAS-961), pyrazolynate, pyrazosulfuron, pyrazoxyfen, pyribenzoxim, pyributicarb, pyridafol, pyridate, pyriftalid, pyriminobac-methyl, pyrithiobac-sodium, quinclorac, quinmerac, quizalofop, quizalofop-P, rimsulfuron, sethoxydim, siduron, simazine, simetryn, sulcotrione, sulfentrazone, sulfometuron-methyl, sulfosulfuron, 2,3,6-TBA, TCA-sodium, tebutam, tebuthiuron, tepraloxydim, terbacil, terbumeton, terbuthyl-azine, terbutryn, thenylchlor, thiazafluron, thiazopyr, thidiazimin, thifensulfuron-methyl, thiobencarb, tiocarbazil, tioclorim, tralkoxydim, tri-allate, triasulfuron, triaziflam, tribenuron, triclopyr, trietazine, trifloxysulfuron, trifluralin, triflusulfuron-methyl, tritosulfuron, UBI-C4874, vernolate.

The concentration of active substance in the above compositions can vary within a wide range, depending on the active compound, the applications to which they are destined, the environmental conditions and the type of formulation adopted. In general, the concentration of active substance preferably ranges from 1 to 90%.

Some examples are now provided for illustrative and non-limiting purposes of the present invention.

EXAMPLE 1 Synthesis of 3,3-dimethyl-1-(tetrazol-5-yl)butane-2-one

NaN₃ (1.71 g) and ZnBr₂ (5.40 g) are added to a suspension of 4,4-dimethyl-3-oxopentanenitrile (3.00 g) in 50 ml of water and 4 ml of isopropylic alcohol and the resulting mixture is stirred at 90° C. for 12 hours.

After completion of the reaction, 15 ml of 10% HCl are added, then the mixture is extracted two times with ethyl acetate; the organic phase is then evaporated under reduced pressure. The residue is stirred with 100 ml of 10% NaOH for 20 minutes, then cooled with an ice bath and acidified with concentrated HCl: the white precipitate is extracted two times with ethyl acetate, which is then dried with Na₂SO₄ and evaporated.

The resulting solid is purified by washing with dichloromethane to obtain 2.75 g of pure product (yield: 68%).

EXAMPLE 2 Synthesis of 3,3-dimethyl-1-(2-methyl-2H-tetrazol-5-yl)butane-2-one and 3,3-dimethyl-1-(1-methyl-1H-tetrazol-5-yl)butane-2-one

K₂CO₃ (1.40 g) and CH₃I (1.32 g) are added to a solution of 3,3-dimethyl-1-(tetrazol-5-yl)butan-2-one (1.42 g) in 35 ml of acetone under an inert atmosphere; the mixture is stirred at room temperature for 20 hours.

The solvent is then evaporated, the residue is taken up with water and extracted two times with ethyl acetate, which is then washed with water, dried with Na₂SO₄ and evaporated.

The raw product is purified by flash chromatography, isolating the two isomers 3,3-dimethyl-1-(2-methyl-2H-tetrazol-5-yl)butan-2-one (0.60 g, yield: 39%) and 3,3-dimethyl-1-(1-methyl-1H-tetrazol-5-yl)butan-2-one (0.64 g, yield: 42%). The structure of each isomer was assigned according to the NMR spectra.

¹H-NMR (CDCl₃):

(2-methyl isomer) −δ 1.24 (s, 9H, t-butyl), 4.12 (s, 2H, CH₂), 4.32 (s, 3H, N—CH₃)

(1-methyl isomer) −δ 1.19 (s, 9H, t-butyl), 3.90 (s, 3H, N—CH₃), 4.17 (s, 2H, CH₂)

EXAMPLE 3 Synthesis of 1-(2-chloro-4-(methylsulphonyl)phenyl]-4,4-dimethyl-2-(1-methyl-1H-tetrazol-5-yl)pentane-1,3-dione (Compound No 1)

Under an inert atmosphere, Mg(OEt)₂ (0.279 g) is added to a solution of 3,3-dimethyl-1-(1-methyl-1H-tetrazol-5-yl)butan-2-one (0.64 g) in 16 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 16 ml of dry tetrahydrofuran, under an inert atmosphere, then a solution of 2-chloro-4-(methylsulphonyl)benzoyl chloride (1.04 g) in dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the solvent is evaporated and the residue is taken up with water and ethyl acetate; after acidification with 10% HCl the organic phase is recovered and extracted three times with aqueous NaHCO₃ saturated solution. The combined basic aqueous phases are acidified and extracted three times with ethyl acetate, which is then dried with Na₂SO₄ and evaporated, obtaining an off-white solid.

The raw product is purified by filtration over silica gel eluting with dichloromethane/methanol 8:2, then by washing the obtained solid with acetone, thus obtaining 0.60 g of product as a white solid (yield: 45%, m.p. 195-200° C.).

¹H-NMR (CDCl₃): δ 1.07 (s, 9H, t-butyl), 3.01 (s, 3H, SO₂CH₃), 3.76 (s, 3H, N—CH₃), 7.30-7.94 (m, 3H, arom. H's)

EXAMPLE 4 Synthesis of 1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(2-methyl-2H-tetrazol-5-yl)pentane-1,3-dione (Compound No 2)

Under an inert atmosphere, Mg(OEt)₂ (0.257 g) is added to a solution of starting 3,3-dimethyl-1-(2-methyl-2H-tetrazol-5-yl)butan-2-one (0.59 g) in 16 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 16 ml of dry tetrahydrofuran, under an inert atmosphere, then a solution of 2,4-dichlorobenzoyl chloride (0.746 g) in dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the solvent is evaporated and the residue is taken up with water and extracted with ethyl acetate; the organic phase is washed with diluted HCl, with brine, then dried with Na₂SO₄ and evaporated.

The raw product is purified by flash chromatography to obtain 0.49 g of product (yield: 43%).

¹H-NMR (CDCl₃): (mixture of two keto-enolic tautomers) δ 1.05, 1.10 (2s, 9H, t-butyl), 4.19, 4.33 (2s, 3H, N—CH₃), 6.62 (s, 1H, CO—CH—CO), 7.04-7.50 (m, 3H, arom. H's)

EXAMPLE 5 Synthesis of 2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-1-(4-chlorophenyl)-3-(cyclopropyl)propane-1,3-dione (Compound No 3)

Under an inert atmosphere, Mg(OEt)₂ (0.209 g) is added to a solution of 2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-1-(4-chlorophenyl)ethanone (0.50 g) in 10 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 10 ml of dry tetrahydrofuran, under an inert atmosphere, then cyclopropanecarbonylchloride (0.208 g) is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the solvent is evaporated and the residue is taken up with water and extracted with ethyl acetate; the organic phase is washed with diluted HCl, with brine, then dried with Na₂SO₄ and evaporated.

The raw product is purified by flash chromatography to obtain 0.28 g of pure product (yield: 44%).

¹H-NMR (CDCl₃): δ 1.01-1.43 (m, 4H, CH₂—CH₂), 1.20 (s, 9H, t-butyl), 2.12-2.22 (m, 1H, CH), 7.26 (s, 4H, arom. H's)

EXAMPLE 6 Synthesis of 1-(4-chlorophenyl)-2-(2H-tetrazol-5-yl)ethanone

NaN₃ (1.19 g) and ZnBr (3.76 g) are added to a suspension of 3-(4-chlorophenyl)-3-oxopropanenitrile (3.00 g) in 30 ml of H₂O and 4 ml of isopropylic acid and the resulting mixture is stirred at 90° C. for 12 hours.

After completion of the reaction, 15 ml of 10% HCl are added, then the mixture is extracted two times with ethyl acetate; the combined organic phases are then evaporated under reduced pressure. The residue is stirred with 100 ml of 10% NaOH for 6 hours, then the mixture is cooled with an ice bath and acidified with concentrated HCl: the white precipitate is extracted two times with ethyl acetate, which is then dried with Na₂SO₄ and evaporated.

The resulting solid is purified by digestion in ethyl acetate to obtain 1.76 g of pure product (yield: 47%)

¹H-NMR (acetone-d₆): δ 4.98 (s, 2H, CH₂), 7.60-8.20 (m, 4H, arom. H's)

EXAMPLE 7 Synthesis of 1-(4-chlorophenyl)-2-(2-methyl-2H-tetrazol-5-yl)ethanone and 1-(4-chlorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethanone

K₂CO₃ (0.47 g) and CH₃I (0.32 g) are added to a solution of 1-(4-chlorophenyl)-2-(2H-tetrazol-5-yl)ethanone (0.50 g) in 15 ml of acetone, under an inert atmosphere; the mixture is stirred at room temperature for 20 hours.

The solvent is then evaporated, the residue is taken up with water and extracted two times with ethyl acetate, which is then washed with water, dried with Na₂SO₄ and evaporated, thus obtaining a solid raw product (0.56 g) containing the two isomers (1-(4-chlorophenyl)-2-(2-methyl-2H-tetrazol-5-yl)ethanone and 1-(4-chlorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethanone), which is used for the following reaction.

EXAMPLE 8 Synthesis of 1-(4-chlorophenyl)-3-cyclopropyl-2-(2-methyl-2H-tetrazol-5-yl)propane-1,3-dione (Compound No 4) and 1-(4-chlorophenyl)-3-cyclopropyl-2-(1-methyl-1H-tetrazol-5-yl)propane-1,3-dione (Compound No 5)

Under an inert atmosphere, Mg(OEt)₂ (0.263 g) is added to a solution of the starting mixture of 1-(4-chlorophenyl)-2-(2-methyl-2H-tetrazol-5-yl)ethanone and 1-(4-chlorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethanone (0.53 g) in 10 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 10 ml of dry tetrahydrofuran, under an inert atmosphere, then cyclopropanecarbonylchloride (0.235 g) is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the solvent is evaporated and the residue is taken up with water and extracted with ethyl acetate; the organic phase is washed with diluted HCl, with brine, then dried with Na₂SO₄ and evaporated.

The raw product is purified by flash chromatography to obtain 0.26 g of 2-methyl isomer (yield: 37%) and 0.17 g of 1-methyl isomer (yield: 24%).

¹H-NMR (CDCl₃):

(2-methyl isomer) —δ 0.90-1.67 (m, 5H, ciclopropyl), 4.29 (s, 3H, N—CH₃), 7.18 (s, 4H, arom. H's)

(1-methyl isomer) −δ 0.9-1.61 (m, 5H, ciclopropyl), 3.49 (s, 3H, N—CH₃), 7.12-7.27 (m, 4H, arom. H's)

EXAMPLE 9 Synthesis of 1-cyclopropyl-2-(tetrazol-5-yl)ethanone

NaN₃ (5.0 g) and ZnBr (14.5 g) are added to a suspension of 3-cyclopropyl-3-oxopropanenitrile (7.0 g) in 130 ml of water and 10 ml of isopropylic alcohol and the resulting mixture is stirred at 100° C. for 12 hours.

After completion of the reaction, 60 ml of 10% HCl are added, then the mixture is extracted three times with ethyl acetate; the organic phase is then evaporated under reduced pressure. The residue is stirred with 400 ml of 1% NaOH for 20 hours, cooled with an ice bath and acidified with 10% HCl; the mixture is extracted three times with ethyl acetate, which is then dried with Na₂SO₄ and evaporated.

The resulting solid is purified by washing with CH₂Cl₂ to obtain 3.6 g of pure product (yield: 37%).

EXAMPLE 10 Synthesis of 1-cyclopropyl-2-(2-methyl-2H-tetrazol-5-yl)ethanone and 1-cyclopropyl-2-(1-methyl-1H-tetrazol-5-yl)ethanone

K₂CO₃ (4.85 g) and CH₃I (3.99 g) are added to a solution of 1-cyclopropyl-2-(tetrazol-5-yl)ethanone (3.56 g) in 90 ml of acetone, under an inert atmosphere; the mixture is then stirred at room temperature for 20 hours.

The solvent is then evaporated, the residue is taken up with water/ethyl acetate and the mixture is acidified to pH 1-2 with HCl 10%; the aqueous phase is extracted two more times with ethyl acetate; the combined organic phases are then washed with brine, dried with Na₂SO₄ and evaporated.

The raw product is purified by flash chromatography, isolating the two isomers 2-methyl (1.95 g, yield: 50%) and 1-methyl (1.13 g, yield: 29%).

¹H-NMR (CDCl₃):

(2-methyl isomer) −δ 0.90-1.16 (m, 4H, CH₂—CH₂), 2.06 (m, 1H, COCH), 4.15 (s, 2H, COCH₂), 4.33 (s, 3H, N—CH₃)

(1-methyl isomer) −δ 0.98-1.18 (m, 4H, CH₂—CH₂), 2.07 (m, 1H, COCH), 3.96 (s, 2H, COCH₂), 4.25 (s, 3H, N—CH₃)

EXAMPLE 11 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-cyclopropyl-2-(2-methyl-2H-tetrazol-5-yl)propane-1,3-dione (Compound No 6, corresponding to compound No 610 in table 2)

Under an inert atmosphere, Mg(OEt)₂ (0.383 g) is added to a solution of 1-cyclopropyl-2-(2-methyl-2H-tetrazol-5-yl)ethanone (0.80 g) in 22 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 15 ml of dry tetarhydrofuran, under an inert atmosphere, then a suspension of 2-chloro-4-(methylsulphonyl)benzoyl chloride (0.96 g) in 20 ml of dry tetrahydrofuran is added ; the stirred mixture is refluxed for 5 more hours.

After completion of the reaction, the solvent is evaporated and the residue is taken up with water and ethyl acetate; after acidification with 10% HCl the organic phase is recovered and extracted three times with aqueous NaHCO₃. The combined basic aqueous phases are acidified and extracted three times with ethyl acetate, which is then dried with Na₂SO₄ and evaporated.

The raw product is purified by washing with warm ethyl acetate, to obtain 0.58 g of product as an orange solid (yield: 40%; m.p.: 220° C.).

¹H-NMR (CDCl₃): δ 1.02-1.96 (m, 5H, cyclopropyl), 3.03 (s, 3H, SO₂CH₃), 4.21 (s, 3H, N—CH₃), 7.42-7.86 (m, 3H, arom. H's), 17.52 (s, 1H, OH).

EXAMPLE 12 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-cyclopropyl-2-(1-methyl-1H-tetrazol-5-yl)propane-1,3-dione (Compound No 7, corresponding to compound No 605 in table 2)

Under an inert atmosphere, Mg(OEt)₂ (0.278 g) is added to a solution of starting 1-cyclopropyl-2-(1-methyl-1H-tetrazol5-yl)ethanone (0.58 g) in 15 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 2 ml of dry tetrahydrofuran, under an inert atmosphere, then a suspension of 2-chloro-4((methylsulphonyl)benzoyl chloride (0.97 g) in 16 ml of dry tetrahydrofuran is added; the stirred mixture is refluxed for 5 more hours.

The solvent is then evaporated and the residue is taken up with water and ethyl acetate; after acidification with 10% HCl the organic phase is collected and extracted two times with aqueous NaHCO₃. The combined basic aqueous phases are acidified and extracted three times with ethyl acetate, which is then dried with Na₂SO₄ and evaporated.

The raw product is purified by flash chromatography, to obtain 0.81 g of product as an orange solid (yield: 61%; m.p.: 104° C.).

¹H-NMR (CDCl₃): δ 1.09-1.42 (m, 5H, cyclopropyl), 3.02 (s, 3H, SO₂CH₃), 3.91 (s, 3H, N—CH₃), 7.47-7.89 (m, 3H, arom. H's), 17.44 (s, 1E, OH).

EXAMPLE 13 Synthesis of 1-(4-chloro-2-nitrophenyl)-2-3-cyclopropyl-(1-methyl-1H-tetrazol-5-yl)propane-1,3-dione (Compound No 8, Corresponding to Compound No 968 in Table 2)

Under an inert atmosphere, Mg(OEt)₂ (0.263 g) is added to a solution of 1-cyclopropyl-2-(1-methyl-1H-tetrazol5-yl)ethanone (0.55 g) in 15 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 7 ml of dry tetrahydrofuran, under an inert atmosphere, then a solution of the 4-chloro-2-nitrobenzoyl chloride (0.80 g) in 8 ml of dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

The solvent is then evaporated and the residue is taken up with water and ethyl acetate; after acidification with 10% HCl the organic phase is collected and extracted two times with aqueous NaHCO₃. The combined basic aqueous phases are acidified and extracted three times with ethyl acetate, which is then dried with Na₂SO₄ and evaporated.

The raw product is purified by flash chromatography, to obtain 0.72 g of product as an orange solid (yield: 61%; m.p.: 152° C.).

¹H-NMR (CDCl₃): δ 1.05-1-52 (m, 5H, cyclopropyl), 3.92 (s, 3H, N—CH₃), 7.39-7.93 (m, 3H, arom. H's), 17.07 (s, 1H, OH).

EXAMPLE 14 Synthesis of 3-cyclopropyl-1-[4-(methylsuiphonyl)-2-nitrophenyl]-2-(2-methyl-2H-tetrazol-5-yl)propane-1,3-dione (Compound No 9, Corresponding to Compound No 247 in Table 2)

Under an inert atmosphere, Mg(OEt)₂ (0.171 g) is added to a solution of 1-cyclopropyl-2-(2-methyl-2H-tetrazol5-yl)ethanone (0.35 g) in 9 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 3 ml of dry tetrahydrofuran, under an inert atmosphere, then a solution of 4-methylsulphonyl-2-nitrobenzoyl chloride (0.61 g) in 6 ml of dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

The solvent is then evaporated and the residue is taken up with water and ethyl acetate; after acidification with 10% HCl the organic phase is collected and extracted three times with aqueous NaHCO₃. The combined basic aqueous phases are slowly acidified to pH 5 and extracted with ethyl acetate, which is then washed three times with pH 5 buffered solution until all the benzoic acid is eliminated, dried with Na₂SO₄ and evaporated.

The resulting solid is purified by filtration over silica gel eluting with ethyl acetate to obtain 0.24 g of pure product as a light brown solid (yield: 61%; m.p 186° C., decomposition).

¹H-NMR (CDCl₃): δ 1.08-1.99 (m, 5H, cyclopropyl), 3.09 (s; 3H, SO₂CH₃), 4.17 (s, 3H, N—CH₃), 7.47-8.62 (m, 3H, arom. H's), 17.19 (s, 1H, OH).

EXAMPLE 15 Synthesis of 1-cyclopropyl-2-(4-methyl-1,3-thiazol-2-yl)ethanone

Under an inert atmosphere and in dried glassware, 2,4-dimethyl-1,3-thiazole (3.15 g) is dissolved in 90 ml of anhydrous tetrahydrofuran; 17.4 ml of 1.6 M butyllithium solution in hexanes are then added dropwise: the solution temperature rises to about 40° C.; after the addition, the mixture is stirred for 30 minutes, allowing the temperature to return to about ₂5° C.

The reaction mixture is then cooled in an ice bath and a solution of ethyl cyclopropanecarboxylate (3.17 g) in 15 ml of anhydrous tetrahydrofuran is quickly added; the ice bath is removed and the resulting solution is stirred at 50° C. for 3 hours.

After completion of the reaction, the solvent is removed at reduced pressure and the residue taken up with 5% HCl, which is washed with a little portion of diethyl ether, then slowly neutralized to pH 7-7.5 and extracted three times with diethyl ether.

The combined organic phases are dried with Na₂SO₄ and evaporated, yielding a dark oil, which is purified by flash chromatography to obtain 0.72 g of desired product as an oil (yield: 14%).

¹H-NMR (CDCl₃): δ 0.89-1.24 (m, 4H, CH₂CH₂), 2.06 (m, 1H, CH), 2.43 (s, 3H, CH₃), 4.23 (s, 2H, CH₂), 6.83 (s, 1H, thiazole H)

EXAMPLE 16 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-cyclopropyl-2-(4-methyl-1,3-thiazol-2-yl)propane-1,3-dione (Compound No 10, Corresponding to Compound No 485 in Table 2)

Under an inert atmosphere, Mg(OEt)₂ (0.316 g) is added to a solution of 1-cyclopropyl-2-(4-methyl-1,3-thiazol-2-yl)ethanone (0.72 g) in 18 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 3 ml of dry tetrahydrofuran, under an inert atmosphere, then a suspension of 2-chloro-4(methylsulphonyl)benzoyl chloride (1.11 g) in 15 ml of dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the solvent is evaporated and the residue is taken up with ethyl acetate and 1% HCl, then the mixture is neutralized with NaHCO₃ and extracted three times with ethyl acetate; the combined organic phases are washed with brine, dried with Na₂SO₄ and evaporated.

The resulting solid is purified by washing with diethyl ether to obtain 1.06 g of pure product as an off-white solid (yield: 67%; m.p.: 199° C.)

¹H-NMR (CDCl₃): δ 0.51-1.35 (m, 5H, cyclopropyl), 2.43 (2s, 3H, Ar—CH₃), 3.07 (s, 3H, SO₂CH₃), 6.59 (2s, 1H, thiazole H), 7.58-8.02 (m, 3H, arom. H's), 14.78 (s, 1H, OH).

MS-DCI: m/z 398 (M+1).

EXAMPLE 17 Synthesis of 1-cyclopropyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethanone

Under an inert atmosphere, acetamidoxime (1.56 g) is added to a solution of methyl 3-cyclopropyl-3-oxopropanoate (3.0 g) in 50 ml of toluene; the stirred mixture is heated to 130° C. while distilling off the solvent and methanol formed in the reaction.

When all the solvent has been removed, 50 ml of toluene and 1.56 g of acetamidoxime are added again to the residue and the distillation continued until all of this second portion of solvent has been removed.

The residue is then purified by flash chromatography to obtain 1.48 g of pure product as a violet oil (yield: 42%).

¹H-NMR (CDCl₃): δ 0.95-1.18 (m, 4H, CH₂CH₂), 2.00 (m, 1H, CH), 2.40 (s, 3H, CH₃), 4.14 (s, 2H, CH₂).

EXAMPLE 18 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-cyclopropyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)propane-1,3-dione (Compound No 11, Corresponding to Compound No 385 in Table 2)

Under an inert atmosphere, Mg(OEt)₂ (0.239 g) is added to a solution of 1-cyclopropyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethanone (0.50 g) in 13 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 3 ml of dry tetrahydrofuran, under an inert atmosphere, then a suspension of 2-chloro-4-(methylsulphonyl)benzoyl chloride (0.84 g) in 10 ml of dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the solvent is evaporated and the residue is taken up with ethyl acetate and 1% HCl, then neutralized with aqueous NaHCO₃ and extracted three times with 5% NaOH; the combined basic aqueous phases are acidified and extracted three times with ethyl acetate, which is then washed with brine, dried with Na₂SO₄ and evaporated.

The resulting solid is purified by washing with diethyl ether to obtain 0.90 g of pure product as an off-white solid (yield: 78%; m.p.: 188° C.).

¹H-NMR (CDCl₃): δ 1.19-1.48 (m, 4H, CH₂CH₂), 2.29 (2s, 3H, Ar—CH₃), 2.55 (m, 1H, CH), 3.06 (s, 3H, SO₂CH₃), 7.46-7.93 (m, 3H, arom. H's), 17.93 (bs, 1H, OH).

EXAMPLE 19 Synthesis of 1-(4-chloro-2-nitrophenil)-3-cyclopropyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)propane-1,3-dione (Compound No 12, Corresponding to Compound No 748 in Table 2)

Under an inert atmosphere, Mg(OEt)₂ (0.215 g) is added to a solution of 1-ciclopropyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethanone (0.45 g) in 12 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 6 ml of dry tetrahydrofuran, under an inert atmosphere, then a solution of 4-chloro-2-nitrobenzoyl chloride (0.66 g) in 6 ml of dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the solvent is evaporated and the residue is taken up with ethyl acetate and 1% HCl, then neutralized with aqueous NaHCO₃ and extracted three times with 5% NaOH; the combined basic aqueous phases are acidified and extracted three times with ethyl acetate, which is then washed with brine, dried with Na₂SO₄ and evaporated.

The resulting solid is purified by washing with a little portion of diethyl ether to obtain 0.51 g of pure product as an off-white solid (yield: 54%; m.p.: 127° C.).

¹H-NMR (CDCl₃): δ 1.18-1.49 (m, 4H, CH₂CH₂), 2.25 (2s, 3H, Ar—CH₃), 2.47 (m, 1H, CH), 7.16-8.15 (m, 3H, arom. H's), 17.61 (bs, 1H, OH).

EXAMPLE 20 Synthesis of 1-cyclopropyl-2-(pyridin-2-yl)ethanone

Under an inert atmosphere and in dried glassware, 2-picoline (9.43 g) is dissolved in 95 ml of anhydrous tetrahydrofuran; 63.1 ml of 1.6 M buthyllithium solution in hexanes are then added: the solution temperature rises to about 40° C.; after the addition, the mixture is stirred for 30 minutes at 40° C.

A solution of methyl cyclopropanecarboxylate (5.07 g) in 5 ml of anhydrous tetrahydrofuran is then quickly added and the mixture is stirred for 1 h at 40° C.

The mixture is then cautiously diluted with water and the organic solvent evaporated at reduced pressure; the residue is taken up with ether and a mixture of 10% HCl and ice; the organic phase is extracted 4 times with HCl 10%.

The combined aqueous acid phases are cautiously treated with 50% NaOH until slightly acid, then basified to pH 8 with solid NaHCO₃; the mixture is then saturated with NaCl and extracted three times with ethyl acetate, which is then dried with Na₂SO₄ and evaporated.

The resulting dark oil is purified by flash chromatography to obtain 5.08 g of desired product as a yellow oil (yield: 31%).

¹H-NMR (CDCl₃): δ 0.82-1.11 (m, 4H, CH₂CH₂), 2.05 (m, 1H, CH), 4.03 (s, 2H, CH₂), 7.19, 7.63, 8.55 (3m, 4H, arom. H's)

EXAMPLE 21 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-cyclopropyl-2-(pyridin-2-yl)propane-1,3-dione (Compound No 13, Corresponding to Compound No 615 in Table 2)

Under an inert atmosphere, Mg(OEt)₂ (0.152 g) is added to a solution of 1-ciclopropyl-2-(pyridin-2-yl)ethanone (0.30 g) in 8 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 2 ml of dry tetrahydrofuran, under an inert atmosphere, then a suspension of 2-chloro-4-(methylsulfonyl)benzoyl chloride (0.52 g) in 6 ml of dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the mixture is diluted with methanol to have an homogeneous solution, then the solvent is evaporated. The residue is taken up with water and extracted three times with ethyl acetate, which is then washed with brine, dried with Na₂SO₄ and evaporated.

The resulting solid is purified by flash chromatography to obtain 0.36 g of product as a yellow amorphous solid (yield: 51%).

¹H-NMR (CDCl₃): δ 0.82-1.70 (m, 5H, cyclopropyl), 3.06 (s, 3H, SO₂CH₃), 7.06-8.21 (m, 7H, arom. H's), 18.05 (bs, 1H, OH).

EXAMPLE 22 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-(cyclopropyl)propane-1,3-dione

Under an inert atmosphere, Mg(OEt)₂ (1.29 g) is added to a solution of t-butyl 3-cyclopropyl-3-oxopropanoate (3.0 g) in 75 ml of dry tetrahydrofuran; the stirred mixture is refluxed for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 20 ml of dry tetrahydrofuran, under an inert atmosphere, then a suspension of 2-chloro-4-(methylsulfonyl)benzoyl chloride (4.52 g) in 55 ml of dry tetrahydrofuran is added; the stirred mixture is refluxed for 3 more hours.

After completion of the reaction, the solvent is evaporated under reduced pressure; the residue is taken up with 30 ml of toluene and p-toluenesulphonic acid (1.13 g) is added, then the stirred mixture is refluxed for 8 hours.

The solid precipitate is filtered off and the solution is evaporated under reduced pressure; the oily residue is purified by flash chromatography to obtain 2.64 g of solid product (yield: 54%).

¹H-NMR (CDCl₃): δ 0.98-1.80 (m, 5H, cyclopropyl), 3.07 (s, 3H, SO₂CH₃), 6.13 (s, 1H, enolic form ═CH—), 7.74-8.00 (m, 3H, arom. H's).

EXAMPLE 23 Synthesis of 1-[2-chloro-4-(thylsulphonyl)phenyl]-3-cyclopropyl-2-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)propane-1,3-dione (Compound No 2918).

Under an inert atmosphere, NaH (60% suspension in mineral oil, 0.27 g) is suspended in 10 ml of dry tetrahydrofuran; a solution of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-(cyclopropyl)propan-1,3-dione (1.76 g) in 15 ml of dry tetrahydrofuran is then slowly added dropwise.

The mixture is stirred for 1 hour, then a solution of 2-methylsulphonyl-5-trifluoromethyl-1,3,4-thiadiazole (1.97 g) in 13 ml of dry tetrahydrofuran is added dropwise.

The stirred mixture is refluxed for 3 hours, then the solvent is evaporated under reduced pressure; the residue is taken up with diethyl ether and extracted two times with aqueous NaRCO₃; the combined aqueous phases are slowly acidified to pH 2-3 and extracted with ethyl acetate, which is then dried with Na₂SO₄ and evaporated.

The residue is purified by flash chromatography, then by washing with diethyl ether, to obtain 0.83 g of product as a white solid (yield: 31%; m.p.: 185° C.).

¹H-NMR (CDCl₃): (mixture of two tautomers) δ 0.50-1.40 (m, 5H, cyclopropyl), 3.10 (s, 3H, SO₂CH₃), 7.60-8.06 (m, 3H, arom. H's), 15.23, 15.39 (2 bs, 1H, OH).

¹⁹F-NMR (CDCl₃): (mixture of two tautomers) δ −60.52, −60.68 (2 S, CF₃).

EXAMPLE 24 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-cyclopropyl-2-(2,4-dinitrophenyl)propane-1,3-dione (Compound No 723)

Under an inert atmosphere, NaH (60% suspension in mineral oil, 0.12 g) is suspended in 2 ml of dry tetrahydrofuran; a solution of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-(cyclopropyl)propan-1,3-dione (0.45 g) in 5 ml of dry tetrahydrofuran is then slowly added dropwise.

The mixture is stirred for 1 hour, then a solution of 2,4-dinitrochlorobenzene (1.52 g) in 2 ml of dry tetrahydrofuran is added dropwise.

The stirred mixture is refluxed for 5 hours, then the solvent is evaporated under reduced pressure; the residue is purified by flash chromatography, then by washing with diethyl ether, to obtain 0.40 g of product (yield: 57%; m.p.: 67° C.).

¹H-NMR (CDCl₃): δ 0.85-1.40 (m, 5H, cyclopropyl), 2.97 (s, 3H, SO₂CH₃), 7.31-8.67 (m, 6H, arom. H's), 16.78 (bs, 1H, OH).

EXAMPLE 25 Synthesis of 2-bromo-1-[2-chloro-4-(methylsulphonyl)phenyl]-3-(cyclopropyl)propane-1,3-dione

Under an inert atmosphere, bromine (0.24 g) is slowly added dropwise to a solution of (1-[2-chloro-4-(methylsulphonyl)phenyl]-3-(cyclopropyl)propan-1,3-dione (0.43 g) in 25 ml of dichloromethane cooled to 5° C., then the mixture is stirred overnight at room temperature.

The solvent is then completely evaporated under reduced pressure and the residue (0.57 g) is used without purification for the following reaction.

¹H-NMR (CDCl₃): δ 1.14-1.34 (m, 4H, cyclic CH₂—CH₂), 2.61 (m, 1H, cyclic CH), 3.10 (s, 3H, SO₂CH₃), 7.52-8.05 (m, 3H, arom. H's), 16.02 (bs, 1H, OH).

EXAMPLE 26 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-cyclopropyl-2-(1,2,4-triazol-1-yl)propane-1,3-dione (Compound No 460)

Under an inert atmosphere, NaH (60% suspension in mineral oil, 0.133 g) is suspended in 2 ml of dry tetrahydrofuran cooled in a water bath, then 1,2,4-triazole (0.23 g) is added.

After stirring for 30 minutes at room temperature, a solution of 2-bromo-1-[2-chloro-4-(methylsulphonyl)phenyl]-3-(cyclopropyl)propan-1,3-dione (0.63 g) in 5 ml of dry tetrahydrofuran is added, then the mixture is heated to 50° C. for 8 hours.

After completion of the reaction, the mixture is diluted with water, acidified and extracted three times with ethyl acetate, which is then washed with brine, dried with Na₂SO₄ and evaporated.

The residue is purified by flash chromatography, then by washing with ethyl ether to obtain 0.23 g of solid product (yield: 38%; m.p.: 162° C.).

¹H-NMR (CDCl₃): δ 1.09-1.40 (m, 5H, cyclopropyl), 3.01 (s, 3H, SO₂CH₃), 7.38-8.05 (m, 5H, arom. H's), 16.23 (bs, 1H, OH).

EXAMPLE 27 Synthesis of 1-[2-chloro-4-(methylsulphonyl)phenyl]-3-cyclopropyl-2-[1,1-dioxido-3-oxo-1,2-benzisothiazol-2 (3H)-yl]propane-1,3-dione (Compound No 2919)

Under an inert atmosphere, NaH (60% suspension in mineral oil, 0.114 g) is suspended in 3 ml of dry tetrahydrofuran cooled in a water bath, then saccharine (0.52 g) is added.

After stirring for 30 minutes at room temperature, a solution of 2-bromo-1-[2-chloro-4-(methylsulphonyl)phenyl]-3-(cyclopropyl)propan-1,3-dione (0.54 g) in 8 ml of dry tetrahydrofuran is added, then the mixture is heated to 50° C. for 6 hours.

After completion of the reaction, the solvent is evaporated; the residue is taken up with water, acidified and extracted three times with ethyl acetate, which is then washed with brine, dried with Na₂SO₄ and evaporated.

The residue is purified by flash chromatography, then by washing with ethyl ether to obtain 0.31 g of product as an amorphous solid (yield: 45%).

¹H-NMR (CDCl₃): δ 1.09-1.45 (m, 4H, cyclic CH₂—CH₂), 1.86 (m, 1H, cyclic CH), 2.99 (s, 3H, SO₂CH₃), 7.51-8.08 (m, 7H, arom. H's), 17.19 (bs, 1H, OH).

EXAMPLE 28 Synthesis of 1,1,1-trifluoro-3-pyridin-2-ylacetone

Under an inert atmosphere, 2-picoline (4.72 g) and pyridine (20.0 g) are dissolved in 130 ml of toluene cooled in an ice bath; trifluoroacetic anhydride (31.9 g) is then slowly added dropwise and the mixture is stirred at room temperature for 48 hours.

The mixture is then cautiously poured into 500 ml of 3% Na₂CO₃, and extracted three times with ethyl acetate; the combined organic phases are extracted two times with 5% NaOH, then these combined basic aqueous phases are acidified to pH 6.5 and extracted with ethyl acetate, which is washed with brine, dried with Na₂SO₄ and evaporated.

The raw product is purified by flash chromatography, then by washing with diethyl ether to obtain 4.24 g of product as a yellow solid (yield: 44%).

¹H-NMR (CDCl₃): δ 5.82 (s, 1H, enolic form CH), 6.99-8.10 (m, 4H, arom. H's), 15.88 (bs, 1H, OH).

¹⁹F-NMR (CDCl₃) : δ −74.94 (s, CF₃)

EXAMPLE 29 Synthesis of 1-[2-chloro-4-(methylsuiphonyl)phenyl]-2-(pyridin-2-yl)-4,4,4-trifluorobutane-1,3-dione (Compound N-616)

Under an inert atmosphere, Mg(OEt)₂ (0.336 g) is added to a solution of 1,1,1-trifluoro-3-pyridin-2-ylacetone (0.80 g) in 17 ml of dry tetrahydrofuran; the stirred mixture is stirred at room temperature for 3 hours, then completely evaporated under reduced pressure.

The residue is taken up with 5 ml of dry tetrahydrofuran, under an inert atmosphere, then a suspension of 2-chloro-4-(methylsulfonyl)benzoyl chloride (1.17 g) in 12 ml of dry tetrahydrofuran is added; the mixture is stirred overnight at room temperature.

After completion of the reaction, the mixture is diluted with ethyl acetate, quickly washed with NH₄Cl saturated solution, with brine, then dried with Na₂SO₄ and evaporated.

The residue is taken up with a mixture of diethyl ether and hexane which causes the product to precipitate: 0.24 g of solid are recovered by filtration (yield: 14%; m.p.: 189° C., with decomposition)

¹H-NMR (acetone-d₆): δ 3.09 (s, 3H, SO₂CH₃), 7.07-8.37 (m, 7H, arom. H's).

¹⁹F-NMR (acetone-d₆): δ −67.43 (s, CF₃)

EXAMPLE 30

Following the suitable procedures, some of which are detailed in the examples above, the following compounds, listed in Table 2, have been prepared and identified by elemental analysis and/or ¹H-NMR: (I)

Compound m.p. N A B R (° C.) 14 2-NO₂-4- 1,2,4-oxadiazol-5- H SO₂MePh yl 15 2-NO₂-4- 1,2,4-oxadiazol-5- methyl SO₂MePh yl 16 2-NO₂-4- 1,2,4-oxadiazol-5- i-propyl SO₂MePh yl 17 2-NO₂-4- 1,2,4-oxadiazol-5- cyclopropyl SO₂MePh yl 18 2-NO₂-4- 1,2,4-oxadiazol-5- CF₃ SO₂MePh yl 19 2-NO₂-4- 3-methyl-1,2,4- H SO₂MePh oxadiazol-5-yl 20 2-NO₂-4- 3-methyl-1,2,4- methyl SO₂MePh oxadiazol-5-yl 21 2-NO₂-4- 3-methyl-1,2,4- i-propyl SO₂MePh oxadiazol-5-yl 22 2-NO₂-4- 3-methyl-1,2,4- cyclopropyl SO₂MePh oxadiazol-5-yl 23 2-NO₂-4- 3-methyl-1,2,4- CF₃ SO₂MePh oxadiazol-5-yl 24 2-NO₂-4- 3-trifluoromethyl- H SO₂MePh 1,2,4-oxadiazol- 5-yl 25 2-NO₂-4- 3-trifluoromethyl- methyl SO₂MePh 1,2,4-oxadiazol- 5-yl 26 2-NO₂-4- 3-trifluoromethyl- i-propyl SO₂MePh 1,2,4-oxadiazol- 5-yl 27 2-NO₂-4- 3-trifluoromethyl- cyclopropyl SO₂MePh 1,2,4-oxadiazol- 5-yl 28 2-NO₂-4- 3-trifluoromethyl- CF₃ SO₂MePh 1,2,4-oxadiazol- 5-yl 29 2-NO₂-4- 1,2,4-oxadiazol-3- H SO₂MePh yl 30 2-NO₂-4- 1,2,4-oxadiazol-3- methyl SO₂MePh yl 31 2-NO₂-4- 1,2,4-oxadiazol-3- i-propyl SO₂MePh yl 32 2-NO₂-4- 1,2,4-oxadiazol-3- cyclopropyl SO₂MePh yl 33 2-NO₂-4- 1,2,4-oxadiazol-3- CF₃ SO₂MePh yl 34 2-NO₂-4- 5-methyl-1,2,4- H SO₂MePh oxadiazol-3-yl 35 2-NO₂-4- 5-methyl-1,2,4- methyl SO₂MePh oxadiazol-3-yl 36 2-NO₂-4- 5-methyl-1,2,4- i-propyl SO₂MePh oxadiazol-3-yl 37 2-NO₂-4- 5-methyl-1,2,4- cyclopropyl SO₂MePh oxadiazol-3-yl 38 2-NO₂-4- 5-methyl-1,2,4- CF₃ SO₂MePh oxadiazol-3-yl 39 2-NO₂-4- 5-trifluoromethyl- H SO₂MePh 1,2,4-oxadiazol- 3-yl 40 2-NO₂-4- 5-trifluoromethyl- methyl SO₂MePh 1,2,4-oxadiazol- 3-yl 41 2-NO₂-4- 5-trifluoromethyl- i-propyl SO₂MePh 1,2,4-oxadiazol- 3-yl 42 2-NO₂-4- 5-trifluoromethyl- cyclopropyl SO₂MePh 1,2,4-oxadiazol- 3-yl 43 2-NO₂-4- 5-trifluoromethyl- CF₃ SO₂MePh 1,2,4-oxadiazol- 3-yl 44 2-NO₂-4- 5-chloro-1,2,4- H SO₂MePh oxadiazol-3-yl 45 2-NO₂-4- 5-chloro-1,2,4- methyl SO₂MePh oxadiazol-3-yl 46 2-NO₂-4- 5-chloro-1,2,4- i-propyl SO₂MePh oxadiazol-3-yl 47 2-NO₂-4- 5-chloro-1,2,4- cyclopropyl SO₂MePh oxadiazol-3-yl 48 2-NO₂-4- 5-chloro-1,2,4- CF₃ SO₂MePh oxadiazol-3-yl 49 2-NO₂-4- 1,3,4-oxadiazol-2- H SO₂MePh yl 50 2-NO₂-4- 1,3,4-oxadiazol-2- methyl SO₂MePh yl 51 2-NO₂-4- 1,3,4-oxadiazol-2- i-propyl SO₂MePh yl 52 2-NO₂-4- 1,3,4-oxadiazol-2- cyclopropyl SO₂MePh yl 53 2-NO₂-4- 1,3,4-oxadiazol-2- CF₃ SO₂MePh yl 54 2-NO₂-4- 5-methylsulfonyl- H SO₂MePh 1,3,4-oxadiazol- 2-yl 55 2-NO₂-4- 5-methylsulfonyl- methyl SO₂MePh 1,3,4-oxadiazol- 2-yl 56 2-NO₂-4- 5-methylsulfonyl- i-propyl SO₂MePh 1,3,4-oxadiazol- 2-yl 57 2-NO₂-4- 5-methylsulfonyl- cyclopropyl SO₂MePh 1,3,4-oxadiazol- 2-yl 58 2-NO₂-4- 5-methylsulfonyl- CF₃ SO₂MePh 1,3,4-oxadiazol- 2-yl 59 2-NO₂-4- 5-methyl-1,3,4- H SO₂MePh oxadiazol-2-yl 60 2-NO₂-4- 5-methyl-1,3,4- methyl SO₂MePh oxadiazol-2-yl 61 2-NO₂-4- 5-methyl-1,3,4- i-propyl SO₂MePh oxadiazol-2-yl 62 2-NO₂-4- 5-methyl-1,3,4- cyclopropyl SO₂MePh oxadiazol-2-yl 63 2-NO₂-4- 5-methyl-1,3,4- CF₃ SO₂MePh oxadiazol-2-yl 64 2-NO₂-4- 5-trifluoromethyl- H SO₂MePh 1,3,4-oxadiazol- 2-yl 65 2-NO₂-4- 5-trifluoromethyl- methyl SO₂MePh 1,3,4-oxadiazol- 2-yl 66 2-NO₂-4- 5-trifluoromethyl- i-propyl SO₂MePh 1,3,4-oxadiazol- 2-yl 67 2-NO₂-4- 5-trifluoromethyl- cyclopropyl SO₂MePh 1,3,4-oxadiazol- 2-yl 68 2-NO₂-4- 5-trifluoromethyl- CF₃ SO₂MePh 1,3,4-oxadiazol- 2-yl 69 2-NO₂-4- 1,2,3-triazol-4-yl H SO₂MePh 70 2-NO₂-4- 1,2,3-triazol-4-yl methyl SO₂MePh 71 2-NO₂-4- 1,2,3-triazol-4-yl i-propyl SO₂MePh 72 2-NO₂-4- 1,2,3-triazol-4-yl cyclopropyl SO₂MePh 73 2-NO₂-4- 1,2,3-triazol-4-yl CF₃ SO₂MePh 74 2-NO₂-4- 1-methyl-1,2,3- H SO₂MePh triazol-4-yl 75 2-NO₂-4- 1-methyl-1,2,3- methyl SO₂MePh triazol-4-yl 76 2-NO₂-4- 1-methyl-1,2,3- i-propyl SO₂MePh triazol-4-yl 77 2-NO₂-4- 1-methyl-1,2,3- cyclopropyl SO₂MePh triazol-4-yl 78 2-NO₂-4- 1-methyl-1,2,3- CF₃ SO₂MePh triazol-4-yl 79 2-NO₂-4- 2-methyl-1,2,3- H SO₂MePh triazol-4-yl 80 2-NO₂-4- 2-methyl-1,2,3- methyl SO₂MePh triazol-4-yl 81 2-NO₂-4- 2-methyl-1,2,3- i-propyl SO₂MePh triazol-4-yl 82 2-NO₂-4- 2-methyl-1,2,3- cyclopropyl SO₂MePh triazol-4-yl 83 2-NO₂-4- 2-methyl-1,2,3- CF₃ SO₂MePh triazol-4-yl 84 2-NO₂-4- 1,2,3-triazol-1-yl H SO₂MePh 85 2-NO₂-4- 1,2,3-triazol-1-yl methyl SO₂MePh 86 2-NO₂-4- 1,2,3-triazol-1-yl i-propyl SO₂MePh 87 2-NO₂-4- 1,2,3-triazol-1-yl cyclopropyl SO₂MePh 88 2-NO₂-4- 1,2,3-triazol-1-yl CF₃ SO₂MePh 89 2-NO₂-4- 1,2,3-triazol-2-yl H SO₂MePh 90 2-NO₂-4- 1,2,3-triazol-2-yl methyl SO₂MePh 91 2-NO₂-4- 1,2,3-triazol-2-yl i-propyl SO₂MePh 92 2-NO₂-4- 1,2,3-triazol-2-yl cyclopropyl SO₂MePh 93 2-NO₂-4- 1,2,3-triazol-2-yl CF₃ SO₂MePh 94 2-NO₂-4- 1,2,4-triazol-1-yl H SO₂MePh 95 2-NO₂-4- 1,2,4-triazol-1-yl methyl SO₂MePh 96 2-NO₂-4- 1,2,4-triazol-1-yl i-propyl SO₂MePh 97 2-NO₂-4- 1,2,4-triazol-1-yl cyclopropyl SO₂MePh 98 2-NO₂-4- 1,2,4-triazol-1-yl CF₃ SO₂MePh 99 2-NO₂-4- imidazol-2-yl H SO₂MePh 100 2-NO₂-4- imidazol-2-yl methyl SO₂MePh 101 2-NO₂-4- imidazol-2-yl i-propyl SO₂MePh 102 2-NO₂-4- imidazol-2-yl cyclopropyl SO₂MePh 103 2-NO₂-4- imidazol-2-yl CF₃ SO₂MePh 104 2-NO₂-4- imidazol-1-yl H SO₂MePh 105 2-NO₂-4- imidazol-1-yl methyl SO₂MePh 106 2-NO₂-4- imidazol-1-yl i-propyl SO₂MePh 107 2-NO₂-4- imidazol-1-yl cyclopropyl SO₂MePh 108 2-NO₂-4- imidazol-1-yl CF₃ SO₂MePh 109 2-NO₂-4- imidazol-4-yl H SO₂MePh 110 2-NO₂-4- imidazol-4-yl methyl SO₂MePh 111 2-NO₂-4- imidazol-4-yl i-propyl SO₂MePh 112 2-NO₂-4- imidazol-4-yl cyclopropyl SO₂MePh 113 2-NO₂-4- imidazol-4-yl CF₃ SO₂MePh 114 2-NO₂-4- thiazol-2-yl H SO₂MePh 115 2-NO₂-4- thiazol-2-yl methyl SO₂MePh 116 2-NO₂-4- thiazol-2-yl i-propyl SO₂MePh 117 2-NO₂-4- thiazol-2-yl cyclopropyl SO₂MePh 118 2-NO₂-4- thiazol-2-yl CF₃ SO₂MePh 119 2-NO₂-4- 4-methylthiazol- H SO₂MePh 2-yl 120 2-NO₂-4- 4-methylthiazol- methyl SO₂MePh 2-yl 121 2-NO₂-4- 4-methylthiazol- i-propyl SO₂MePh 2-yl 122 2-NO₂-4- 4-methylthiazol- cyclopropyl SO₂MePh 2-yl 123 2-NO₂-4- 4-methylthiazol- CF₃ SO₂MePh 2-yl 124 2-NO₂-4- oxazol-2-yl H SO₂MePh 125 2-NO₂-4- oxazol-2-yl methyl SO₂MePh 126 2-NO₂-4- oxazol-2-yl i-propyl SO₂MePh 127 2-NO₂-4- oxazol-2-yl cyclopropyl SO₂MePh 128 2-NO₂-4- oxazol-2-yl CF₃ SO₂MePh 129 2-NO₂-4- 4,5-dimethyl- H SO₂MePh oxazol-2-yl 130 2-NO₂-4- 4,5-dimethyl- methyl SO₂MePh oxazol-2-yl 131 2-NO₂-4- 4,5-dimethyl- i-propyl SO₂MePh oxazol-2-yl 132 2-NO₂-4- 4,5-dimethyl- cyclopropyl SO₂MePh oxazol-2-yl 133 2-NO₂-4- 4,5-dimethyl- CF₃ SO₂MePh oxazol-2-yl 134 2-NO₂-4- 2-oxazolin-2-yl H SO₂MePh 135 2-NO₂-4- 2-oxazolin-2-yl methyl SO₂MePh 136 2-NO₂-4- 2-oxazolin-2-yl i-propyl SO₂MePh 137 2-NO₂-4- 2-oxazolin-2-yl cyclopropyl SO₂MePh 138 2-NO₂-4- 2-oxazolin-2-yl CF₃ SO₂MePh 139 2-NO₂-4- 4,4-dimethyl-2- H SO₂MePh oxazolin-2-yl 140 2-NO₂-4- 4,4-dimethyl-2- methyl SO₂MePh oxazol-2-yl 141 2-NO₂-4- 4,4-dimethyl-2- i-propyl SO₂MePh oxazol-2-yl 142 2-NO₂-4- 4,4-dimethyl-2- cyclopropyl SO₂MePh oxazol-2-yl 143 2-NO₂-4- 4,4-dimethyl-2- CF₃ SO₂MePh oxazol-2-yl 144 2-NO₂-4- 1,2,4-thiadiazol- H SO₂MePh 5-yl 145 2-NO₂-4- 1,2,4-thiadiazol- methyl SO₂MePh 5-yl 146 2-NO₂-4- 1,2,4-thiadiazol- i-propyl SO₂MePh 5-yl 147 2-NO₂-4- 1,2,4-thiadiazol- cyclopropyl SO₂MePh 5-yl 148 2-NO₂-4- 1,2,4-thiadiazol- CF₃ SO₂MePh 5-yl 149 2-NO₂-4- 3-methyl-1,2,4- H SO₂MePh thiadiazol-5-yl 150 2-NO₂-4- 3-methyl-1,2,4- methyl SO₂MePh thiadiazol-5-yl 151 2-NO₂-4- 3-methyl-1,2,4- i-propyl SO₂MePh thiadiazol-5-yl 152 2-NO₂-4- 3-methyl-1,2,4- cyclopropyl SO₂MePh thiadiazol-5-yl 153 2-NO₂-4- 3-methyl-1,2,4- CF₃ SO₂MePh thiadiazol-5-yl 154 2-NO₂-4- 3-trifluoromethyl- H SO₂MePh 1,2,4-thiadiazol- 5-yl 155 2-NO₂-4- 3-trifluoromethyl- methyl SO₂MePh 1,2,4-thiadiazol- 5-yl 156 2-NO₂-4- 3-trifluoromethyl- i-propyl SO₂MePh 1,2,4-thiadiazol- 5-yl 157 2-NO₂-4- 3-trifluoromethyl- cyclopropyl SO₂MePh 1,2,4-thiadiazol- 5-yl 158 2-NO₂-4- 3-trifluoromethyl- CF₃ SO₂MePh 1,2,4-thiadiazol- 5-yl 159 2-NO₂-4- 1,2,4-thiadiazol- H SO₂MePh 3-yl 160 2-NO₂-4- 1,2,4-thiadiazol- methyl SO₂MePh 3-yl 161 2-NO₂-4- 1,2,4-thiadiazol- i-propyl SO₂MePh 3-yl 162 2-NO₂-4- 1,2,4-thiadiazol- cyclopropyl SO₂MePh 3-yl 163 2-NO₂-4- 1,2,4-thiadiazol- CF₃ SO₂MePh 3-yl 164 2-NO₂-4- 5-methyl-1,2,4- H SO₂MePh thiadiazol-3-yl 165 2-NO₂-4- 5-methyl-1,2,4- methyl SO₂MePh thiadiazol-3-yl 166 2-NO₂-4- 5-methyl-1,2,4- i-propyl SO₂MePh thiadiazol-3-yl 167 2-NO₂-4- 5-methyl-1,2,4- cyclopropyl SO₂MePh thiadiazol-3-yl 168 2-NO₂-4- 5-methyl-1,2,4- CF₃ SO₂MePh thiadiazol-3-yl 169 2-NO₂-4- 5-trifluoromethyl- H SO₂MePh 1,2,4-thiadiazol- 3-yl 170 2-NO₂-4- 5-trifluoromethyl- methyl SO₂MePh 1,2,4-thiadiazol- 3-yl 171 2-NO₂-4- 5-trifluoromethyl- i-propyl SO₂MePh 1,2,4-thiadiazol- 3-yl 172 2-NO₂-4- 5-trifluoromethyl- cyclopropyl SO₂MePh 1,2,4-thiadiazol- 3-yl 173 2-NO₂-4- 5-trifluoromethyl- CF₃ SO₂MePh 1,2,4-thiadiazol- 3-yl 174 2-NO₂-4- 1,3,4-thiadiazol- H SO₂MePh 2-yl 175 2-NO₂-4- 1,3,4-thiadiazol- methyl SO₂MePh 2-yl 176 2-NO₂-4- 1,3,4-thiadiazol- i-propyl SO₂MePh 2-yl 177 2-NO₂-4- 1,3,4-thiadiazol- cyclopropyl SO₂MePh 2-yl 178 2-NO₂-4- 1,3,4-thiadiazol- CF₃ SO₂MePh 2-yl 179 2-NO₂-4- 5-methylsulfonyl- H SO₂MePh 1,3,4-thiadiazol- 2-yl 180 2-NO₂-4- 5-methylsulfonyl- methyl SO₂MePh 1,3,4-thiadiazol- 2-yl 181 2-NO₂-4- 5-methylsulfonyl- i-propyl SO₂MePh 1,3,4-thiadiazol- 2-yl 182 2-NO₂-4- 5-methylsulfonyl- cyclopropyl SO₂MePh 1,3,4-thiadiazol- 2-yl 183 2-NO₂-4- 5-methylsulfonyl- CF₃ SO₂MePh 1,3,4-thiadiazol- 2-yl 184 2-NO₂-4- 5-methyl-1,3,4- H SO₂MePh thiadiazol-2-yl 185 2-NO₂-4- 5-methyl-1,3,4- methyl SO₂MePh thiadiazol-2-yl 186 2-NO₂-4- 5-methyl-1,3,4- i-propyl SO₂MePh thiadiazol-2-yl 187 2-NO₂-4- 5-methyl-1,3,4- cyclopropyl SO₂MePh thiadiazol-2-yl 188 2-NO₂-4- 5-methyl-1,3,4- CF₃ SO₂MePh thiadiazol-2-yl 189 2-NO₂-4- benzoxazol-2-yl H SO₂MePh 190 2-NO₂-4- benzoxazol-2-yl methyl SO₂MePh 191 2-NO₂-4- benzoxazol-2-yl i-propyl SO₂MePh 192 2-NO₂-4- benzoxazol-2-yl cyclopropyl SO₂MePh 193 2-NO₂-4- benzoxazol-2-yl CF₃ SO₂MePh 194 2-NO₂-4- 6-methyl- H SO₂MePh benzoxazol-2-yl 195 2-NO₂-4- 6-methyl- methyl SO₂MePh benzoxazol-2-yl 196 2-NO₂-4- 6-methyl- i-propyl SO₂MePh benzoxazol-2-yl 197 2-NO₂-4- 6-methyl- cyclopropyl SO₂MePh benzoxazol-2-yl 198 2-NO₂-4- 6-methyl- CF₃ SO₂MePh benzoxazol-2-yl 199 2-NO₂-4- benzothiazol-2-yl H SO₂MePh 200 2-NO₂-4- benzothiazol-2-yl methyl \ SO₂MePh 201 2-NO₂-4- benzothiazol-2-yl i-propyl SO₂MePh 202 2-NO₂-4- benzothiazol-2-yl cyclopropyl SO₂MePh 203 2-NO₂-4- benzothiazol-2-yl CF₃ SO₂MePh 204 2-NO₂-4- pyrazol-1-yl H SO₂MePh 205 2-NO₂-4- pyrazol-1-yl methyl SO₂MePh 206 2-NO₂-4- pyrazol-1-yl i-propyl SO₂MePh 207 2-NO₂-4- pyrazol-1-yl cyclopropyl SO₂MePh 208 2-NO₂-4- pyrazol-1-yl CF₃ SO₂MePh 209 2-NO₂-4- pyrazol-3-yl H SO₂MePh 210 2-NO₂-4- pyrazol-3-yl methyl SO₂MePh 211 2-NO₂-4- pyrazol-3-yl i-propyl SO₂MePh 212 2-NO₂-4- pyrazol-3-yl cyclopropyl SO₂MePh 213 2-NO₂-4- pyrazol-3-yl CF₃ SO₂MePh 214 2-NO₂-4- 1-methylpyrazol- H SO₂MePh 3-yl 215 2-NO₂-4- 1-methylpyrazol- methyl SO₂MePh 3-yl 216 2-NO₂-4- 1-methylpyrazol- i-propyl SO₂MePh 3-yl 217 2-NO₂-4- 1-methylpyrazol- cyclopropyl SO₂MePh 3-yl 218 2-NO₂-4- 1-methylpyrazol- CF₃ SO₂MePh 3-yl 219 2-NO₂-4- tetrazol-1-yl H SO₂MePh 220 2-NO₂-4- tetrazol-1-yl methyl SO₂MePh 221 2-NO₂-4- tetrazol-1-yl i-propyl SO₂MePh 222 2-NO₂-4- tetrazol-1-yl cyclopropyl SO₂MePh 223 2-NO₂-4- tetrazol-1-yl CF₃ SO₂MePh 224 2-NO₂-4- 5-methyltetrazol- H SO₂MePh 1-yl 225 2-NO₂-4- 5-methyltetrazol- methyl SO₂MePh 1-yl 226 2-NO₂-4- 5-methyltetrazol- i-propyl SO₂MePh 1-yl 227 2-NO₂-4- 5-methyltetrazol- cyclopropyl SO₂MePh 1-yl 228 2-NO₂-4- 5-methyltetrazol- CF₃ SO₂MePh 1-yl 229 2-NO₂-4- tetrazol-2-yl H SO₂MePh 230 2-NO₂-4- tetrazol-2-yl methyl SO₂MePh 231 2-NO₂-4- tetrazol-2-yl i-propyl SO₂MePh 232 2-NO₂-4- tetrazol-2-yl cyclopropyl SO₂MePh 233 2-NO₂-4- tetrazol-2-yl CF₃ SO₂MePh 234 2-NO₂-4- 5-methyltetrazol- H SO₂MePh 2-yl 235 2-NO₂-4- 5-methyltetrazol- methyl SO₂MePh 2-yl 236 2-NO₂-4- 5-methyltetrazol- i-propyl SO₂MePh 2-yl 237 2-NO₂-4- 5-methyltetrazol- cyclopropyl SO₂MePh 2-yl 238 2-NO₂-4- 5-methyltetrazol- CF₃ SO₂MePh 2-yl 239 2-NO₂-4- 1-methyltetrazol- H SO₂MePh 5-yl 240 2-NO₂-4- 1-methyltetrazol- methyl SO₂MePh 5-yl 241 2-NO₂-4- 1-methyltetrazol- i-propyl SO₂MePh 5-yl 242 2-NO₂-4- 1-methyltetrazol- cyclopropyl SO₂MePh 5-yl 243 2-NO₂-4- 1-methyltetrazol- CF₃ SO₂MePh 5-yl 244 2-NO₂-4- 2-methyltetrazol- H SO₂MePh 5-yl 245 2-NO₂-4- 2-methyltetrazol- methyl SO₂MePh 5-yl 246 2-NO₂-4- 2-methyltetrazol- i-propyl SO₂MePh 5-yl 247 2-NO₂-4- 2-methyltetrazol- cyclopropyl 186 SO₂MePh 5-yl 248 2-NO₂-4- 2-methyltetrazol- CF₃ SO₂MePh 5-yl 249 2-NO₂-4- pyridin-2-yl H SO₂MePh 250 2-NO₂-4- pyridin-2-yl methyl SO₂MePh 251 2-NO₂-4- pyridin-2-yl i-propyl SO₂MePh 252 2-NO₂-4- pyridin-2-yl cyclopropyl SO₂MePh 253 2-NO₂-4- pyridin-2-yl CF₃ SO₂MePh 254 2-NO₂-4- pyridin-4-yl H SO₂MePh 255 2-NO₂-4- pyridin-4-yl methyl SO₂MePh 256 2-NO₂-4- pyridin-4-yl i-propyl SO₂MePh 257 2-NO₂-4- pyridin-4-yl cyclopropyl SO₂MePh 258 2-NO₂-4- pyridin-4-yl CF₃ SO₂MePh 259 2-NO₂-4- pyridin-3-yl H SO₂MePh 260 2-NO₂-4- pyridin-3-yl methyl SO₂MePh 261 2-NO₂-4- pyridin-3-yl i-propyl SO₂MePh 262 2-NO₂-4- pyridin-3-yl cyclopropyl SO₂MePh 263 2-NO₂-4- pyridin-3-yl CF₃ SO₂MePh 264 2-NO₂-4- 3-nitropyridin- H SO₂MePh 4-yl 265 2-NO₂-4- 3-nitropyridin- methyl SO₂MePh 4-yl 266 2-NO₂-4- 3-nitropyridin- i-propyl SO₂MePh 4-yl 267 2-NO₂-4- 3-nitropyridin- cyclopropyl SO₂MePh 4-yl 268 2-NO₂-4- 3-nitropyridin- CF₃ SO₂MePh 4-yl 269 2-NO₂-4- 5-cyanopyridin- H SO₂MePh 2-yl 270 2-NO₂-4- 5-cyanopyridin- methyl SO₂MePh 2-yl 271 2-NO₂-4- 5-cyanopyridin- i-propyl SO₂MePh 2-yl 272 2-NO₂-4- 5-cyanopyridin- cyclopropyl SO₂MePh 2-yl 273 2-NO₂-4- 5-cyanopyridin- CF₃ SO₂MePh 2-yl 274 2-NO₂-4- 5-trifluoro- H SO₂MePh methylpyridin- 2-yl 275 2-NO₂-4- 5-trifluoro- methyl SO₂MePh methylpyridin- 2-yl 276 2-NO₂-4- 5-trifluoro- i-propyl SO₂MePh methylpyridin- 2-yl 277 2-NO₂-4- 5-trifluoro- cyclopropyl SO₂MePh methylpyridin- 2-yl 278 2-NO₂-4- 5-trifluoro- CF₃ SO₂MePh methylpyridin- 2-yl 279 2-NO₂-4- pyrimidin-2-yl H SO₂MePh 280 2-NO₂-4- pyrimidin-2-yl methyl SO₂MePh 281 2-NO₂-4- pyrimidin-2-yl i-propyl SO₂MePh 282 2-NO₂-4- pyrimidin-2-yl cyclopropyl SO₂MePh 283 2-NO₂-4- pyrimidin-2-yl CF₃ SO₂MePh 284 2-NO₂-4- pyrimidin-4-yl H SO₂MePh 285 2-NO₂-4- pyrimidin-4-yl methyl SO₂MePh 286 2-NO₂-4- pyrimidin-4-yl i-propyl SO₂MePh 287 2-NO₂-4- pyrimidin-4-yl cyclopropyl SO₂MePh 288 2-NO₂-4- pyrimidin-4-yl CF₃ SO₂MePh 289 2-NO₂-4- 6-chloro- methyl SO₂MePh pyrimidin-4-yl 290 2-NO₂-4- 6-chloro- i-propyl SO₂MePh pyrimidin-4-yl 291 2-NO₂-4- 6-chloro- cyclopropyl SO₂MePh pyrimidin-4-yl 292 2-NO₂-4- 6-chloro- CF₃ SO₂MePh pyrimidin-4-yl 293 2-NO₂-4- pyridazin-3-yl H SO₂MePh 294 2-NO₂-4- pyridazin-3-yl methyl SO₂MePh 295 2-NO₂-4- pyridazin-3-yl i-propyl SO₂MePh 296 2-NO₂-4- pyridazin-3-yl cyclopropyl SO₂MePh 297 2-NO₂-4- pyridazin-3-yl CF₃ SO₂MePh 298 2-NO₂-4- 6-chloro- methyl SO₂MePh pyridazin-3-yl 299 2-NO₂-4- 6-chloro- i-propyl SO₂MePh pyridazin-3-yl 300 2-NO₂-4- 6-chloro- cyclopropyl SO₂MePh pyridazin-3-yl 301 2-NO₂-4- 6-chloro- CF₃ SO₂MePh pyridazin-3-yl 302 2-NO₂-4- pyrazin-2-yl methyl SO₂MePh 303 2-NO₂-4- pyrazin-2-yl i-propyl SO₂MePh 304 2-NO₂-4- pyrazin-2-yl cyclopropyl SO₂MePh 305 2-NO₂-4- pyrazin-2-yl CF₃ SO₂MePh 306 2-NO₂-4- triazin-2-yl methyl SO₂MePh 307 2-NO₂-4- triazin-2-yl i-propyl SO₂MePh 308 2-NO₂-4- triazin-2-yl cyclopropyl SO₂MePh 309 2-NO₂-4- triazin-2-yl CF₃ SO₂MePh 310 2-NO₂-4- quinolin-2-yl methyl SO₂MePh 311 2-NO₂-4- quinolin-2-yl i-propyl SO₂MePh 312 2-NO₂-4- quinolin-2-yl cyclopropyl SO₂MePh 313 2-NO₂-4- quinolin-2-yl CF₃ SO₂MePh 314 2-NO₂-4- 4,4,6-trimethyl- H SO₂MePh 5,6-dihydro-1, 3(4H)-oxazin-2-yl 315 2-NO₂-4- 4,4,6-trimethyl- methyl SO₂MePh 5,6-dihydro-1, 3(4H)-oxazin-2-yl 316 2-NO₂-4- 4,4,6-trimethyl- i-propyl SO₂MePh 5,6-dihydro-1, 3(4H)-oxazin-2-yl 317 2-NO₂-4- 4,4,6-trimethyl- cyclopropyl SO₂MePh 5,6-dihydro-1, 3(4H)-oxazin-2-yl 318 2-NO₂-4- 4,4,6-trimethyl- CF₃ SO₂MePh 5,6-dihydro-1, 3(4H)-oxazin-2-yl 319 2-NO₂-4- 2-oxazolidinon- H SO₂MePh 3-yl 320 2-NO₂-4- 2-oxazolidinon- methyl SO₂MePh 3-yl 321 2-NO₂-4- 2-oxazolidinon- i-propyl SO₂MePh 3-yl 322 2-NO₂-4- 2-oxazolidinon- cyclopropyl SO₂MePh 3-yl 323 2-NO₂-4- 2-oxazolidinon- CF₃ SO₂MePh 3-yl 324 2-NO₂-4- 2-pyrrolidinon- methyl SO₂MePh 1-yl 325 2-NO₂-4- 2-pyrrolidinon- i-propyl SO₂MePh 1-yl 326 2-NO₂-4- 2-pyrrolidinon- cyclopropyl SO₂MePh 1-yl 327 2-NO₂-4- 2-pyrrolidinon- CF₃ SO₂MePh 1-yl 328 2-NO₂-4- 3-methylisoxazol- methyl SO₂MePh 5-yl 329 2-NO₂-4- 3-methylisoxazol- i-propyl SO₂MePh 5-yl 330 2-NO₂-4- 3-methylisoxazol- cyclopropyl SO₂MePh 5-yl 331 2-NO₂-4- 3-methylisoxazol- CF₃ SO₂MePh 5-yl 332 2-NO₂-4- 2-NO₂-4- H SO₂MePh SO₂MePh 333 2-NO₂-4- 2-NO₂-4- methyl SO₂MePh SO₂MePh 334 2-NO₂-4- 2-NO₂-4- i-propyl SO₂MePh SO₂MePh 335 2-NO₂-4- 2-NO₂-4- cyclopropyl SO₂MePh SO₂MePh 336 2-NO₂-4- 2-NO₂-4- CF₃ SO₂MePh SO₂MePh 337 2-NO₂-4- 2-Cl-4-SO₂MePh H SO₂MePh 338 2-NO₂-4- 2-Cl-4-SO₂MePh methyl SO₂MePh 339 2-NO₂-4- 2-Cl-4-SO₂MePh i-propyl SO₂MePh 340 2-NO₂-4- 2-Cl-4-SO₂MePh cyclopropyl SO₂MePh 341 2-NO₂-4- 2-Cl-4-SO₂MePh CF₃ SO₂MePh 342 2-NO₂-4- 2-NO₂-4-CF₃Ph H SO₂MePh 343 2-NO₂-4- 2-NO₂-4-CF₃Ph methyl SO₂MePh 344 2-NO₂-4- 2-NO₂-4-CF₃Ph i-propyl SO₂MePh 345 2-NO₂-4- 2-NO₂-4-CF₃Ph cyclopropyl SO₂MePh 346 2-NO₂-4- 2-NO₂-4-CF₃Ph CF₃ SO₂MePh 347 2-NO₂-4- 2-NO₂-4-ClPh H SO₂MePh 348 2-NO₂-4- 2-NO₂-4-ClPh methyl SO₂MePh 349 2-NO₂-4- 2-NO₂-4-ClPh i-propyl SO₂MePh 350 2-NO₂-4- 2-NO₂-4-ClPh cyclopropyl SO₂MePh 351 2-NO₂-4- 2-NO₂-4-ClPh CF₃ SO₂MePh 352 2-NO₂-4- 2-Cl-4-NO₂Ph H SO₂MePh 353 2-NO₂-4- 2-Cl-4-NO₂Ph methyl SO₂MePh 354 2-NO₂-4- 2-Cl-4-NO₂Ph i-propyl SO₂MePh 355 2-NO₂-4- 2-Cl-4-NO₂Ph cyclopropyl SO₂MePh 356 2-NO₂-4- 2-Cl-4-NO₂Ph CF₃ SO₂MePh 357 2-NO₂-4- 2,4-(NO₂)₂Ph H SO₂MePh 358 2-NO₂-4- 2,4-(NO₂)₂Ph methyl SO₂MePh 359 2-NO₂-4- 2,4-(NO₂)₂Ph i-propyl SO₂MePh 360 2-NO₂-4- 2,4-(NO₂)₂Ph cyclopropyl SO₂MePh 361 2-NO₂-4- 2,4-(NO₂)₂Ph CF₃ SO₂MePh 362 2-NO₂-4- 4-F-3-NO₂Ph H SO₂MePh 363 2-NO₂-4- 4-F-3-NO₂Ph methyl SO₂MePh 364 2-NO₂-4- 4-F-3-NO₂Ph i-propyl SO₂MePh 365 2-NO₂-4- 4-F-3-NO₂Ph cyclopropyl SO₂MePh 366 2-NO₂-4- 4-F-3-NO₂Ph CF₃ SO₂MePh 367 2-NO₂-4- 3,5-(CF₃)₂Ph H SO₂MePh 368 2-NO₂-4- 3,5-(CF₃)₂Ph methyl SO₂MePh 369 2-NO₂-4- 3,5-(CF₃)₂Ph i-propyl SO₂MePh 370 2-NO₂-4- 3,5-(CF₃)₂Ph cyclopropyl SO₂MePh 371 2-NO₂-4- 3,5-(CF₃)₂Ph CF₃ SO₂MePh 372 2-NO₂-4- 2-SO₂Me-4- H SO₂MePh CF₃Ph 373 2-NO₂-4- 2-SO₂Me-4- methyl SO₂MePh CF₃Ph 374 2-NO₂-4- 2-SO₂Me-4- i-propyl SO₂MePh CF₃Ph 375 2-NO₂-4- 2-SO₂Me-4- cyclopropyl SO₂MePh CF₃Ph 376 2-NO₂-4- 2-SO₂Me-4- CF₃ SO₂MePh CF₃Ph 377 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5- H yl 378 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5- methyl yl 379 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5- i-propyl yl 380 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5- cyclopropyl yl 381 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-5- CF₃ yl 382 2-Cl-4-SO₂MePh 3-methyl-1,2,4- H oxadiazol-5-yl 383 2-Cl-4-SO₂MePh 3-methyl-1,2,4- methyl oil oxadiazol-5-yl 384 2-Cl-4-SO₂MePh 3-methyl-1,2,4- i-propyl 174 oxadiazol-5-yl 385 2-Cl-4-SO₂MePh 3-methyl-1,2,4- cyclopropyl 188 oxadiazol-5-yl 386 2-Cl-4-SO₂MePh 3-methyl-1,2,4- CF₃ oxadiazol-5-yl 387 2-Cl-4-SO₂MePh 3-trifluoromethyl- H 1,2,4-oxadiazol- 5-yl 388 2-Cl-4-SO₂MePh 3-trifluoromethyl- methyl 1,2,4-oxadiazol- 5-yl 389 2-Cl-4-SO₂MePh 3-trifluoromethyl- i-propyl 1,2,4-oxadiazol- 5-yl 390 2-Cl-4-SO₂MePh 3-trifluoromethyl- cyclopropyl 1,2,4-oxadiazol- 5-yl 391 2-Cl-4-SO₂MePh 3-trifluoromethyl- CF₃ 1,2,4-oxadiazol- 5-yl 392 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3- H yl 393 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3- methyl yl 394 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3- i-propyl yl 395 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3- cyclopropyl yl 396 2-Cl-4-SO₂MePh 1,2,4-oxadiazol-3- CF₃ yl 397 2-Cl-4-SO₂MePh 5-methyl-1,2,4- H oxadiazol-3-yl 398 2-Cl-4-SO₂MePh 5-methyl-1,2,4- methyl oxadiazol-3-yl 399 2-Cl-4-SO₂MePh 5-methyl-1,2,4- i-propyl oxadiazol-3-yl 400 2-Cl-4-SO₂MePh 5-methyl-1,2,4- cyclopropyl oxadiazol-3-yl 401 2-Cl-4-SO₂MePh 5-methyl-1,2,4- CF₃ oxadiazol-3-yl 402 2-Cl-4-SO₂MePh 5-trifluoromethyl- H 1,2,4-oxadiazol- 3-yl 403 2-Cl-4-SO₂MePh 5-trifluoromethyl- methyl 1,2,4-oxadiazol- 3-yl 404 2-Cl-4-SO₂MePh 5-trifluoromethyl- i-propyl 1,2,4-oxadiazol- 3-yl 405 2-Cl-4-SO₂MePh 5-trifluoromethyl- cyclopropyl 1,2,4-oxadiazol- 3-yl 406 2-Cl-4-SO₂MePh 5-trifluoromethyl- CF₃ 1,2,4-oxadiazol- 3-yl 407 2-Cl-4-SO₂MePh 5-chloro-1,2,4- H oxadiazol-3-yl 408 2-Cl-4-SO₂MePh 5-chloro-1,2,4- methyl oxadiazol-3-yl 409 2-Cl-4-SO₂MePh 5-chloro-1,2,4- i-propyl oxadiazol-3-yl 410 2-Cl-4-SO₂MePh 5-chloro-1,2,4- cyclopropyl oxadiazol-3-yl 411 2-Cl-4-SO₂MePh 5-chloro-1,2,4- CF₃ oxadiazol-3-yl 412 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2- H yl 413 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2- methyl yl 414 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2- i-propyl yl 415 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2- cyclopropyl yl 416 2-Cl-4-SO₂MePh 1,3,4-oxadiazol-2- CF₃ yl 417 2-Cl-4-SO₂MePh 5-methylsulfonyl- H 1,3,4-oxadiazol- 2-yl 418 2-Cl-4-SO₂MePh 5-methylsulfonyl- methyl 1,3,4-oxadiazol- 2-yl 419 2-Cl-4-SO₂MePh 5-methylsulfonyl- i-propyl 1,3,4-oxadiazol- 2-yl 420 2-Cl-4-SO₂MePh 5-methylsulfonyl- cyclopropyl 1,3,4-oxadiazol- 2-yl 421 2-Cl-4-SO₂MePh 5-methylsulfonyl- CF₃ 1,3,4-oxadiazol- 2-yl 422 2-Cl-4-SO₂MePh 5-methyl-1,3,4- H oxadiazol-2-yl 423 2-Cl-4-SO₂MePh 5-methyl-1,3,4- methyl oxadiazol-2-yl 424 2-Cl-4-SO₂MePh 5-methyl-1,3,4- i-propyl oxadiazol-2-yl 425 2-Cl-4-SO₂MePh 5-methyl-1,3,4- cyclopropyl oxadiazol-2-yl 426 2-Cl-4-SO₂MePh 5-methyl-1,3,4- CF₃ oxadiazol-2-yl 427 2-Cl-4-SO₂MePh 5-trifluoromethyl- H 1,3,4-oxadiazol- 2-yl 428 2-Cl-4-SO₂MePh 5-trifluoromethyl- methyl 1,3,4-oxadiazol- 2-yl 429 2-Cl-4-SO₂MePh 5-trifluoromethyl- i-propyl 1,3,4-oxadiazol- 2-yl 430 2-Cl-4-SO₂MePh 5-trifluoromethyl- cyclopropyl 1,3,4-oxadiazol- 2-yl 431 2-Cl-4-SO₂MePh 5-trifluoromethyl- CF₃ 1,3,4-oxadiazol- 2-yl 432 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl H 433 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl methyl 434 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl i-propyl 435 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl cyclopropyl 436 2-Cl-4-SO₂MePh 1,2,3-triazol-4-yl CF₃ 437 2-Cl-4-SO₂MePh 1-methyl-1,2,3- H triazol-4-yl 438 2-Cl-4-SO₂MePh 1-methyl-1,2,3- methyl triazol-4-yl 439 2-Cl-4-SO₂MePh 1-methyl-1,2,3- i-propyl triazol-4-yl 440 2-Cl-4-SO₂MePh 1-methyl-1,2,3- cyclopropyl triazol-4-yl 441 2-Cl-4-SO₂MePh 1-methyl-1,2,3- CF₃ triazol-4-yl 442 2-Cl-4-SO₂MePh 2-methyl-1,2,3- H triazol-4-yl 443 2-Cl-4-SO₂MePh 2-methyl-1,2,3- methyl triazol-4-yl 444 2-Cl-4-SO₂MePh 2-methyl-1,2,3- i-propyl triazol-4-yl 445 2-Cl-4-SO₂MePh 2-methyl-1,2,3- cyclopropyl triazol-4-yl 446 2-Cl-4-SO₂MePh 2-methyl-1,2,3- CF₃ triazol-4-yl 447 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl H 448 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl methyl 449 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl i-propyl 450 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl cyclopropyl 451 2-Cl-4-SO₂MePh 1,2,3-triazol-1-yl CF₃ 452 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl H 453 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl methyl 454 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl i-propyl 455 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl cyclopropyl 456 2-Cl-4-SO₂MePh 1,2,3-triazol-2-yl CF₃ 457 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl H 458 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl methyl 459 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl i-propyl 460 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl cyclopropyl 162 461 2-Cl-4-SO₂MePh 1,2,4-triazol-1-yl CF₃ 462 2-Cl-4-SO₂MePh imidazol-2-yl H 463 2-Cl-4-SO₂MePh imidazol-2-yl methyl 464 2-Cl-4-SO₂MePh imidazol-2-yl i-propyl 465 2-Cl-4-SO₂MePh imidazol-2-yl cyclopropyl 466 2-Cl-4-SO₂MePh imidazol-2-yl CF₃ 467 2-Cl-4-SO₂MePh imidazol-1-yl H 468 2-Cl-4-SO₂MePh imidazol-1-yl methyl 469 2-Cl-4-SO₂MePh imidazol-1-yl i-propyl 470 2-Cl-4-SO₂MePh imidazol-1-yl cyclopropyl 471 2-Cl-4-SO₂MePh imidazol-1-yl CF₃ 472 2-Cl-4-SO₂MePh imidazol-4-yl H 473 2-Cl-4-SO₂MePh imidazol-4-yl methyl 474 2-Cl-4-SO₂MePh imidazol-4-yl i-propyl 475 2-Cl-4-SO₂MePh imidazol-4-yl cyclopropyl 476 2-Cl-4-SO₂MePh imidazol-4-yl CF₃ 477 2-Cl-4-SO₂MePh thiazol-2-yl H 478 2-Cl-4-SO₂MePh thiazol-2-yl methyl 479 2-Cl-4-SO₂MePh thiazol-2-yl i-propyl 480 2-Cl-4-SO₂MePh thiazol-2-yl cyclopropyl 481 2-Cl-4-SO₂MePh thiazol-2-yl CF₃ 482 2-Cl-4-SO₂MePh 4-methylthiazol- H 2-yl 483 2-Cl-4-SO₂MePh 4-methylthiazol- methyl 2-yl 484 2-Cl-4-SO₂MePh 4-methylthiazol- i-propyl 2-yl 485 2-Cl-4-SO₂MePh 4-methylthiazol- cyclopropyl 199 2-yl 486 2-Cl-4-SO₂MePh 4-methylthiazol- CF₃ 2-yl 487 2-Cl-4-SO₂MePh oxazol-2-yl H 488 2-Cl-4-SO₂MePh oxazol-2-yl methyl 489 2-Cl-4-SO₂MePh oxazol-2-yl i-propyl 490 2-Cl-4-SO₂MePh oxazol-2-yl cyclopropyl 491 2-Cl-4-SO₂MePh oxazol-2-yl CF₃ 492 2-Cl-4-SO₂MePh 4,5-dimethyl- H oxazol-2-yl 493 2-Cl-4-SO₂MePh 4,5-dimethyl- methyl oxazol-2-yl 494 2-Cl-4-SO₂MePh 4,5-dimethyl- i-propyl oxazol-2-yl 495 2-Cl-4-SO₂MePh 4,5-dimethyl- cyclopropyl oxazol-2-yl 496 2-Cl-4-SO₂MePh 4,5-dimethyl- CF₃ oxazol-2-yl 497 2-Cl-4-SO₂MePh 2-oxazolin-2-yl H 498 2-Cl-4-SO₂MePh 2-oxazolin-2-yl methyl 499 2-Cl-4-SO₂MePh 2-oxazolin-2-yl i-propyl 500 2-Cl-4-SO₂MePh 2-oxazolin-2-yl cyclopropyl 501 2-Cl-4-SO₂MePh 2-oxazolin-2-yl CF₃ 502 2-Cl-4-SO₂MePh 4,4-dimethyl-2- H oxazolin-2-yl 503 2-Cl-4-SO₂MePh 4,4-dimethyl-2- methyl oxazolin-2-yl 504 2-Cl-4-SO₂MePh 4,4-dimethyl-2- i-propyl oxazolin-2-yl 505 2-Cl-4-SO₂MePh 4,4-dimethyl-2- cyclopropyl oxazolin-2-yl 506 2-Cl-4-SO₂MePh 4,4-dimethyl-2- CF₃ oxazolin-2-yl 507 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- H 5-yl 508 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- methyl 5-yl 509 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- i-propyl 5-yl 510 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- cyclopropyl 5-yl 511 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- CF₃ 5-yl 512 2-Cl-4-SO₂MePh 3-methyl-1,2,4- H thiadiazol-5-yl 513 2-Cl-4-SO₂MePh 3-methyl-1,2,4- methyl thiadiazol-5-yl 514 2-Cl-4-SO₂MePh 3-methyl-1,2,4- i-propyl thiadiazol-5-yl 515 2-Cl-4-SO₂MePh 3-methyl-1,2,4- cyclopropyl thiadiazol-5-yl 516 2-Cl-4-SO₂MePh 3-methyl-1,2,4- CF₃ thiadiazol-5-yl 517 2-Cl-4-SO₂MePh 3-trifluoromethyl- H 1,2,4-thiadiazol- 5-yl 518 2-Cl-4-SO₂MePh 3-trifluoromethyl- methyl 1,2,4-thiadiazol- 5-yl 519 2-Cl-4-SO₂MePh 3-trifluoromethyl- i-propyl 1,2,4-thiadiazol- 5-yl 520 2-Cl-4-SO₂MePh 3-trifluoromethyl- cyclopropyl 1,2,4-thiadiazol- 5-yl 521 2-Cl-4-SO₂MePh 3-trifluoromethyl- CF₃ 1,2,4-thiadiazol- 5-yl 522 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- H 3-yl 523 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- methyl 3-yl 524 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- i-propyl 3-yl 525 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- cyclopropyl 3-yl 526 2-Cl-4-SO₂MePh 1,2,4-thiadiazol- CF₃ 3-yl 527 2-Cl-4-SO₂MePh 5-methyl-1,2,4- H thiadiazol-3-yl 528 2-Cl-4-SO₂MePh 5-methyl-1,2,4- methyl thiadiazol-3-yl 529 2-Cl-4-SO₂MePh 5-methyl-1,2,4- i-propyl thiadiazol-3-yl 530 2-Cl-4-SO₂MePh 5-methyl-1,2,4- cyclopropyl thiadiazol-3-yl 531 2-Cl-4-SO₂MePh 5-methyl-1,2,4- CF₃ thiadiazol-3-yl 532 2-Cl-4-SO₂MePh 5-trifluoromethyl- H 1,2,4-thiadiazol- 3-yl 533 2-Cl-4-SO₂MePh 5-trifluoromethyl- methyl 1,2,4-thiadiazol- 3-yl 534 2-Cl-4-SO₂MePh 5-trifluoromethyl- i-propyl 1,2,4-thiadiazol- 3-yl 535 2-Cl-4-SO₂MePh 5-trifluoromethyl- cyclopropyl 1,2,4-thiadiazol- 3-yl 536 2-Cl-4-SO₂MePh 5-trifluoromethyl- CF₃ 1,2,4-thiadiazol- 3-yl 537 2-Cl-4-SO₂MePh 1,3,4-thiadiazol- H 2-yl 538 2-Cl-4-SO₂MePh 1,3,4-thiadiazol- methyl 2-yl 539 2-Cl-4-SO₂MePh 1,3,4-thiadiazol- i-propyl 2-yl 540 2-Cl-4-SO₂MePh 1,3,4-thiadiazol- cyclopropyl 2-yl 541 2-Cl-4-SO₂MePh 1,3,4-thiadiazol- CF₃ 2-yl 542 2-Cl-4-SO₂MePh 5-methylsulfonyl- H 1,3,4-thiadiazol- 2-yl 543 2-Cl-4-SO₂MePh 5-methylsulfonyl- methyl 1,3,4-thiadiazol- 2-yl 544 2-Cl-4-SO₂MePh 5-methylsulfonyl- i-propyl 1,3,4-thiadiazol- 2-yl 545 2-Cl-4-SO₂MePh 5-methylsulfonyl- cyclopropyl 1,3,4-thiadiazol- 2-yl 546 2-Cl-4-SO₂MePh 5-methylsulfonyl- CF₃ 1,3,4-thiadiazol- 2-yl 547 2-Cl-4-SO₂MePh 5-methyl-1,3,4- H thiadiazol-2-yl 548 2-Cl-4-SO₂MePh 5-methyl-1,3,4- methyl thiadiazol-2-yl 549 2-Cl-4-SO₂MePh 5-methyl-1,3,4- i-propyl thiadiazol-2-yl 550 2-Cl-4-SO₂MePh 5-methyl-1,3,4- cyclopropyl thiadiazol-2-yl 551 2-Cl-4-SO₂MePh 5-methyl-1,3,4- CF₃ thiadiazol-2-yl 552 2-Cl-4-SO₂MePh benzoxazol-2-yl H 553 2-Cl-4-SO₂MePh benzoxazol-2-yl methyl 554 2-Cl-4-SO₂MePh benzoxazol-2-yl i-propyl 555 2-Cl-4-SO₂MePh benzoxazol-2-yl cyclopropyl 556 2-Cl-4-SO₂MePh benzoxazol-2-yl CF₃ 557 2-Cl-4-SO₂MePh 6-methyl- H benzoxazol-2-yl 558 2-Cl-4-SO₂MePh 6-methyl- methyl benzoxazol-2-yl 559 2-Cl-4-SO₂MePh 6-methyl- i-propyl benzoxazol-2-yl 560 2-Cl-4-SO₂MePh 6-methyl- cyclopropyl benzoxazol-2-yl 561 2-Cl-4-SO₂MePh 6-methyl- CF₃ benzoxazol-2-yl 562 2-Cl-4-SO₂MePh benzothiazol-2-yl H 563 2-Cl-4-SO₂MePh benzothiazol-2-yl methyl 564 2-Cl-4-SO₂MePh benzothiazol-2-yl i-propyl 565 2-Cl-4-SO₂MePh benzothiazol-2-yl cyclopropyl 566 2-Cl-4-SO₂MePh benzothiazol-2-yl CF₃ 567 2-Cl-4-SO₂MePh pyrazol-1-yl H 568 2-Cl-4-SO₂MePh pyrazol-1-yl methyl 569 2-Cl-4-SO₂MePh pyrazol-1-yl i-propyl 570 2-Cl-4-SO₂MePh pyrazol-1-yl cyclopropyl 571 2-Cl-4-SO₂MePh pyrazol-1-yl CF₃ 572 2-Cl-4-SO₂MePh pyrazol-3-yl H 573 2-Cl-4-SO₂MePh pyrazol-3-yl methyl 574 2-Cl-4-SO₂MePh pyrazol-3-yl i-propyl 575 2-Cl-4-SO₂MePh pyrazol-3-yl cyclopropyl 576 2-Cl-4-SO₂MePh pyrazol-3-yl CF₃ 577 2-Cl-4-SO₂MePh 1-methylpyrazol- H 3-yl 578 2-Cl-4-SO₂MePh 1-methylpyrazol- methyl 3-yl 579 2-Cl-4-SO₂MePh 1-methylpyrazol- i-propyl 3-yl 580 2-Cl-4-SO₂MePh 1-methylpyrazol- cyclopropyl 3-yl 581 2-Cl-4-SO₂MePh 1-methylpyrazol- CF₃ 3-yl 582 2-Cl-4-SO₂MePh tetrazol-1-yl H 583 2-Cl-4-SO₂MePh tetrazol-1-yl methyl 584 2-Cl-4-SO₂MePh tetrazol-1-yl i-propyl 585 2-Cl-4-SO₂MePh tetrazol-1-yl cyclopropyl 586 2-Cl-4-SO₂MePh tetrazol-1-yl CF₃ 587 2-Cl-4-SO₂MePh 5-methyltetrazol- H 1-yl 588 2-Cl-4-SO₂MePh 5-methyltetrazol- methyl 1-yl 589 2-Cl-4-SO₂MePh 5-methyltetrazol- i-propyl 1-yl 590 2-Cl-4-SO₂MePh 5-methyltetrazol- cyclopropyl 1-yl 591 2-Cl-4-SO₂MePh 5-methyltetrazol- CF₃ 1-yl 592 2-Cl-4-SO₂MePh tetrazol-2-yl H 593 2-Cl-4-SO₂MePh tetrazol-2-yl methyl 594 2-Cl-4-SO₂MePh tetrazol-2-yl i-propyl 595 2-Cl-4-SO₂MePh tetrazol-2-yl cyclopropyl 596 2-Cl-4-SO₂MePh tetrazol-2-yl CF₃ 597 2-Cl-4-SO₂MePh 5-methyltetrazol- H 2-yl 598 2-Cl-4-SO₂MePh 5-methyltetrazol- methyl 2-yl 599 2-Cl-4-SO₂MePh 5-methyltetrazol- i-propyl 2-yl 600 2-Cl-4-SO₂MePh 5-methyltetrazol- cyclopropyl 2-yl 601 2-Cl-4-SO₂MePh 5-methyltetrazol- CF₃ 2-yl 602 2-Cl-4-SO₂MePh 1-methyltetrazol- H 5-yl 603 2-Cl-4-SO₂MePh 1-methyltetrazol- methyl 5-yl 604 2-Cl-4-SO₂MePh 1-methyltetrazol- i-propyl 5-yl 605 2-Cl-4-SO₂MePh 1-methyltetrazol- cyclopropyl 104 5-yl 606 2-Cl-4-SO₂MePh 1-methyltetrazol- CF₃ 5-yl 607 2-Cl-4-SO₂MePh 2-methyltetrazol- t-butile oil 5-yl 608 2-Cl-4-SO₂MePh 2-methyltetrazol- methyl 5-yl 609 2-Cl-4-SO₂MePh 2-methyltetrazol- i-propyl 210 5-yl 610 2-Cl-4-SO₂MePh 2-methyltetrazol- cyclopropyl 220 5-yl 611 2-Cl-4-SO₂MePh 2-methyltetrazol- CF₃ 5-yl 612 2-Cl-4-SO₂MePh pyridin-2-yl H 613 2-Cl-4-SO₂MePh pyridin-2-yl methyl 614 2-Cl-4-SO₂MePh pyridin-2-yl i-propyl 615 2-Cl-4-SO₂MePh pyridin-2-yl cyclopropyl 616 2-Cl-4-SO₂MePh pyridin-2-yl CF₃ 189 617 2-Cl-4-SO₂MePh pyridin-4-yl H 618 2-Cl-4-SO₂MePh pyridin-4-yl methyl 619 2-Cl-4-SO₂MePh pyridin-4-yl i-propyl 620 2-Cl-4-SO₂MePh pyridin-4-yl cyclopropyl 621 2-Cl-4-SO₂MePh pyridin-4-yl CF₃ 622 2-Cl-4-SO₂MePh pyridin-3-yl H 623 2-Cl-4-SO₂MePh pyridin-3-yl methyl 624 2-Cl-4-SO₂MePh pyridin-3-yl i-propyl 625 2-Cl-4-SO₂MePh pyridin-3-yl cyclopropyl 626 2-Cl-4-SO₂MePh pyridin-3-yl CF₃ 627 2-Cl-4-SO₂MePh 3-nitropyridin- H 4-yl 628 2-Cl-4-SO₂MePh 3-nitropyridin- methyl 4-yl 629 2-Cl-4-SO₂MePh 3-nitropyridin- i-propyl 4-yl 630 2-Cl-4-SO₂MePh 3-nitropyridin- cyclopropyl 4-yl 631 2-Cl-4-SO₂MePh 3-nitropyridin- CF₃ 4-yl 632 2-Cl-4-SO₂MePh 5-cyanopyridin- H 2-yl 633 2-Cl-4-SO₂MePh 5-cyanopyridin- methyl 2-yl 634 2-Cl-4-SO₂MePh 5-cyanopyridin- i-propyl 2-yl 635 2-Cl-4-SO₂MePh 5-cyanopyridin- cyclopropyl 2-yl 636 2-Cl-4-SO₂MePh 5-cyanopyridin- CF₃ 2-yl 637 2-Cl-4-SO₂MePh 5-trifluoro- H methylpyridin- 2-yl 638 2-Cl-4-SO₂MePh 5-trifluoro- methyl methylpyridin- 2-yl 639 2-Cl-4-SO₂MePh 5-trifluoro- i-propyl methylpyridin- 2-yl 640 2-Cl-4-SO₂MePh 5-trifluoro- cyclopropyl methylpyridin- 2-yl 641 2-Cl-4-SO₂MePh 5-trifluoro- CF₃ methylpyridin- 2-yl 642 2-Cl-4-SO₂MePh pyrimidin-2-yl H 643 2-Cl-4-SO₂MePh pyrimidin-2-yl methyl 644 2-Cl-4-SO₂MePh pyrimidin-2-yl i-propyl 645 2-Cl-4-SO₂MePh pyrimidin-2-yl cyclopropyl 646 2-Cl-4-SO₂MePh pyrimidin-2-yl CF₃ 647 2-Cl-4-SO₂MePh pyrimidin-4-yl H 648 2-Cl-4-SO₂MePh pyrimidin-4-yl methyl 649 2-Cl-4-SO₂MePh pyrimidin-4-yl i-propyl 650 2-Cl-4-SO₂MePh pyrimidin-4-yl cyclopropyl 651 2-Cl-4-SO₂MePh pyrimidin-4-yl CF₃ 652 2-Cl-4-SO₂MePh 6-chloro- methyl pyrimidin-4-yl 653 2-Cl-4-SO₂MePh 6-chloro- i-propyl pyrimidin-4-yl 654 2-Cl-4-SO₂MePh 6-chloro- cyclopropyl pyrimidin-4-yl 655 2-Cl-4-SO₂MePh 6-chloro- CF₃ pyrimidin-4-yl 656 2-Cl-4-SO₂MePh pyridazin-3-yl H 657 2-Cl-4-SO₂MePh pyridazin-3-yl methyl 658 2-Cl-4-SO₂MePh pyridazin-3-yl i-propyl 659 2-Cl-4-SO₂MePh pyridazin-3-yl cyclopropyl 660 2-Cl-4-SO₂MePh pyridazin-3-yl CF₃ 661 2-Cl-4-SO₂MePh 6-chloro- methyl pyridazin-3-yl 662 2-Cl-4-SO₂MePh 6-chloro- i-propyl pyridazin-3-yl 663 2-Cl-4-SO₂MePh 6-chloro- cyclopropyl pyridazin-3-yl 664 2-Cl-4-SO₂MePh 6-chloro- CF₃ pyridazin-3-yl 665 2-Cl-4-SO₂MePh pyrazin-2-yl methyl 666 2-Cl-4-SO₂MePh pyrazin-2-yl i-propyl 667 2-Cl-4-SO₂MePh pyrazin-2-yl cyclopropyl 668 2-Cl-4-SO₂MePh pyrazin-2-yl CF₃ 669 2-Cl-4-SO₂MePh triazin-2-yl methyl 670 2-Cl-4-SO₂MePh triazin-2-yl i-propyl 671 2-Cl-4-SO₂MePh triazin-2-yl cyclopropyl 672 2-Cl-4-SO₂MePh triazin-2-yl CF₃ 673 2-Cl-4-SO₂MePh quinolin-2-yl methyl 674 2-Cl-4-SO₂MePh quinolin-2-yl i-propyl 675 2-Cl-4-SO₂MePh quinolin-2-yl cyclopropyl 676 2-Cl-4-SO₂MePh quinolin-2-yl CF₃ 677 2-Cl-4-SO₂MePh 4,4,6-trimethyl- H 5,6-dihydro-1, 3(4H)-oxazin-2-yl 678 2-Cl-4-SO₂MePh 4,4,6-trimethyl- methyl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 679 2-Cl-4-SO₂MePh 4,4,6-trimethyl- i-propyl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 680 2-Cl-4-SO₂MePh 4,4,6-trimethyl- cyclopropyl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 681 2-Cl-4-SO₂MePh 4,4,6-trimethyl- CF₃ 5,6-dihydro-1, 3(4H)-oxazin-2-yl 682 2-Cl-4-SO₂MePh 2-oxazolidinon- H 3-yl 683 2-Cl-4-SO₂MePh 2-oxazolidinon- methyl 3-yl 684 2-Cl-4-SO₂MePh 2-oxazolidinon- i-propyl 3-yl 685 2-Cl-4-SO₂MePh 2-oxazolidinon- cyclopropyl 3-yl 686 2-Cl-4-SO₂MePh 2-oxazolidinon- CF₃ 3-yl 687 2-Cl-4-SO₂MePh 2-pyrrolidinon- methyl 1-yl 688 2-Cl-4-SO₂MePh 2-pyrrolidinon- i-propyl 1-yl 689 2-Cl-4-SO₂MePh 2-pyrrolidinon- cyclopropyl 1-yl 690 2-Cl-4-SO₂MePh 2-pyrrolidinon- CF₃ 1-yl 691 2-Cl-4-SO₂MePh 3-methylisoxazol- methyl 5-yl 692 2-Cl-4-SO₂MePh 3-methylisoxazol- i-propyl 5-yl 693 2-Cl-4-SO₂MePh 3-methylisoxazol- cyclopropyl 5-yl 694 2-Cl-4-SO₂MePh 3-methylisoxazol- CF₃ 5-yl 695 2-Cl-4-SO₂MePh 2-NO₂-4- H SO₂MePh 696 2-Cl-4-SO₂MePh 2-NO₂-4- methyl SO₂MePh 697 2-Cl-4-SO₂MePh 2-NO₂-4- i-propyl SO₂MePh 698 2-Cl-4-SO₂MePh 2-NO₂-4- cyclopropyl SO₂MePh 699 2-Cl-4-SO₂MePh 2-NO₂-4- CF₃ SO₂MePh 700 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh H 701 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh methyl 702 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh i-propyl 703 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh cyclopropyl 704 2-Cl-4-SO₂MePh 2-Cl-4-SO₂MePh CF₃ 705 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph H 706 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph methyl 707 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph i-propyl 708 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph cyclopropyl 709 2-Cl-4-SO₂MePh 2-NO₂-4-CF₃Ph CF₃ 710 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh H 711 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh methyl 712 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh i-propyl 713 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh cyclopropyl 714 2-Cl-4-SO₂MePh 2-NO₂-4-ClPh CF₃ 715 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph H 716 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph methyl 717 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph i-propyl 718 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph cyclopropyl 719 2-Cl-4-SO₂MePh 2-Cl-4-NO₂Ph CF₃ 720 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph H 721 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph methyl 722 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph i-propyl 723 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph cyclopropyl  67 724 2-Cl-4-SO₂MePh 2,4-(NO₂)₂Ph CF₃ 725 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph H 726 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph methyl 727 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph i-propyl 728 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph cyclopropyl 729 2-Cl-4-SO₂MePh 4-F-3-NO₂Ph CF₃ 730 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph H 731 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph methyl 732 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph i-propyl 733 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph cyclopropyl 734 2-Cl-4-SO₂MePh 3,5-(CF₃)₂Ph CF₃ 735 2-Cl-4-SO₂MePh 2-SO₂Me-4- H CF₃Ph 736 2-Cl-4-SO₂MePh 2-SO₂Me-4- methyl CF₃Ph 737 2-Cl-4-SO₂MePh 2-SO₂Me-4- i-propyl CF₃Ph 738 2-Cl-4-SO₂MePh 2-SO₂Me-4- cyclopropyl CF₃Ph 739 2-Cl-4-SO₂MePh 2-SO₂Me-4- CF₃ CF₃Ph 740 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5- H yl 741 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5- methyl yl 742 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5- i-propyl yl 743 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5- cyclopropyl yl 744 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-5- CF₃ yl 745 4-Cl-2-NO₂Ph 3-methyl-1,2,4- H oxadiazol-5-yl 746 4-Cl-2-NO₂Ph 3-methyl-1,2,4- methyl oxadiazol-5-yl 747 4-Cl-2-NO₂Ph 3-methyl-1,2,4- i-propyl oxadiazol-5-yl 748 4-Cl-2-NO₂Ph 3-methyl-1,2,4- cyclopropyl 127 oxadiazol-5-yl 749 4-Cl-2-NO₂Ph 3-methyl-1,2,4- CF₃ oxadiazol-5-yl 750 4-Cl-2-NO₂Ph 3-trifluoromethyl- H 1,2,4-oxadiazol- 5-yl 751 4-Cl-2-NO₂Ph 3-trifluoromethyl- methyl 1,2,4-oxadiazol- 5-yl 752 4-Cl-2-NO₂Ph 3-trifluoromethyl- i-propyl 1,2,4-oxadiazol- 5-yl 753 4-Cl-2-NO₂Ph 3-trifluoromethyl- cyclopropyl 1,2,4-oxadiazol- 5-yl 754 4-Cl-2-NO₂Ph 3-trifluoromethyl- CF₃ 1,2,4-oxadiazol- 5-yl 755 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3- H yl 756 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3- methyl yl 757 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3- i-propyl yl 758 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3- cyclopropyl yl 759 4-Cl-2-NO₂Ph 1,2,4-oxadiazol-3- CF₃ yl 760 4-Cl-2-NO₂Ph 5-methyl-1,2,4- H oxadiazol-3-yl 761 4-Cl-2-NO₂Ph 5-methyl-1,2,4- methyl oxadiazol-3-yl 762 4-Cl-2-NO₂Ph 5-methyl-1,2,4- i-propyl oxadiazol-3-yl 763 4-Cl-2-NO₂Ph 5-methyl-1,2,4- cyclopropyl oxadiazol-3-yl 764 4-Cl-2-NO₂Ph 5-methyl-1,2,4- CF₃ oxadiazol-3-yl 765 4-Cl-2-NO₂Ph 5-trifluoromethyl- H 1,2,4-oxadiazol- 3-yl 766 4-Cl-2-NO₂Ph 5-trifluoromethyl- methyl 1,2,4-oxadiazol- 3-yl 767 4-Cl-2-NO₂Ph 5-trifluoromethyl- i-propyl 1,2,4-oxadiazol- 3-yl 768 4-Cl-2-NO₂Ph 5-trifluoromethyl- cyclopropyl 1,2,4-oxadiazol- 3-yl 769 4-Cl-2-NO₂Ph 5-trifluoromethyl- CF₃ 1,2,4-oxadiazol- 3-yl 770 4-Cl-2-NO₂Ph 5-chloro-1,2,4- H oxadiazol-3-yl 771 4-Cl-2-NO₂Ph 5-chloro-1,2,4- methyl oxadiazol-3-yl 772 4-Cl-2-NO₂Ph 5-chloro-1,2,4- i-propyl oxadiazol-3-yl 773 4-Cl-2-NO₂Ph 5-chloro-1,2,4- cyclopropyl oxadiazol-3-yl 774 4-Cl-2-NO₂Ph 5-chloro-1,2,4- CF₃ oxadiazol-3-yl 775 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2- H yl 776 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2- methyl yl 777 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2- i-propyl yl 778 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2- cyclopropyl yl 779 4-Cl-2-NO₂Ph 1,3,4-oxadiazol-2- CF₃ yl 780 4-Cl-2-NO₂Ph 5-methylsulfonyl- H 1,3,4-oxadiazol- 2-yl 781 4-Cl-2-NO₂Ph 5-methylsulfonyl- methyl 1,3,4-oxadiazol- 2-yl 782 4-Cl-2-NO₂Ph 5-methylsulfonyl- i-propyl 1,3,4-oxadiazol- 2-yl 783 4-Cl-2-NO₂Ph 5-methylsulfonyl- cyclopropyl 1,3,4-oxadiazol- 2-yl 784 4-Cl-2-NO₂Ph 5-methylsulfonyl- CF₃ 1,3,4-oxadiazol- 2-yl 785 4-Cl-2-NO₂Ph 5-methyl-1,3,4- H oxadiazol-2-yl 786 4-Cl-2-NO₂Ph 5-methyl-1,3,4- methyl oxadiazol-2-yl 787 4-Cl-2-NO₂Ph 5-methyl-1,3,4- i-propyl oxadiazol-2-yl 788 4-Cl-2-NO₂Ph 5-methyl-1,3,4- cyclopropyl oxadiazol-2-yl 789 4-Cl-2-NO₂Ph 5-methyl-1,3,4- CF₃ oxadiazol-2-yl 790 4-Cl-2-NO₂Ph 5-trifluoromethyl- H 1,3,4-oxadiazol- 2-yl 791 4-Cl-2-NO₂Ph 5-trifluoromethyl- methyl 1,3,4-oxadiazol- 2-yl 792 4-Cl-2-NO₂Ph 5-trifluoromethyl- i-propyl 1,3,4-oxadiazol- 2-yl 793 4-Cl-2-NO₂Ph 5-trifluoromethyl- cyclopropyl 1,3,4-oxadiazol- 2-yl 794 4-Cl-2-NO₂Ph 5-trifluoromethyl- CF₃ 1,3,4-oxadiazol- 2-yl 795 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl H 796 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl methyl 797 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl i-propyl 798 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl cyclopropyl 799 4-Cl-2-NO₂Ph 1,2,3-triazol-4-yl CF₃ 800 4-Cl-2-NO₂Ph 1-methyl-1,2,3- H triazol-4-yl 801 4-Cl-2-NO₂Ph 1-methyl-1,2,3- methyl triazol-4-yl 802 4-Cl-2-NO₂Ph 1-methyl-1,2,3- i-propyl triazol-4-yl 803 4-Cl-2-NO₂Ph 1-methyl-1,2,3- cyclopropyl triazol-4-yl 804 4-Cl-2-NO₂Ph 1-methyl-1,2,3- CF₃ triazol-4-yl 805 4-Cl-2-NO₂Ph 2-methyl-1,2,3- H triazol-4-yl 806 4-Cl-2-NO₂Ph 2-methyl-1,2,3- methyl triazol-4-yl 807 4-Cl-2-NO₂Ph 2-methyl-1,2,3- i-propyl triazol-4-yl 808 4-Cl-2-NO₂Ph 2-methyl-1,2,3- cyclopropyl triazol-4-yl 809 4-Cl-2-NO₂Ph 2-methyl-1,2,3- CF₃ triazol-4-yl 810 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl H 811 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl methyl 812 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl i-propyl 813 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl cyclopropyl 814 4-Cl-2-NO₂Ph 1,2,3-triazol-1-yl CF₃ 815 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl H 816 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl methyl 817 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl i-propyl 818 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl cyclopropyl 819 4-Cl-2-NO₂Ph 1,2,3-triazol-2-yl CF₃ 820 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl H 821 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl methyl 822 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl i-propyl 823 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl cyclopropyl 824 4-Cl-2-NO₂Ph 1,2,4-triazol-1-yl CF₃ 825 4-Cl-2-NO₂Ph imidazol-2-yl H 826 4-Cl-2-NO₂Ph imidazol-2-yl methyl 827 4-Cl-2-NO₂Ph imidazol-2-yl i-propyl 828 4-Cl-2-NO₂Ph imidazol-2-yl cyclopropyl 829 4-Cl-2-NO₂Ph imidazol-2-yl CF₃ 830 4-Cl-2-NO₂Ph imidazol-1-yl H 831 4-Cl-2-NO₂Ph imidazol-1-yl methyl 832 4-Cl-2-NO₂Ph imidazol-1-yl i-propyl 833 4-Cl-2-NO₂Ph imidazol-1-yl cyclopropyl 834 4-Cl-2-NO₂Ph imidazol-1-yl CF₃ 835 4-Cl-2-NO₂Ph imidazol-4-yl H 836 4-Cl-2-NO₂Ph imidazol-4-yl methyl 837 4-Cl-2-NO₂Ph imidazol-4-yl i-propyl 838 4-Cl-2-NO₂Ph imidazol-4-yl cyclopropyl 839 4-Cl-2-NO₂Ph imidazol-4-yl CF₃ 840 4-Cl-2-NO₂Ph thiazol-2-yl H 841 4-Cl-2-NO₂Ph thiazol-2-yl methyl 842 4-Cl-2-NO₂Ph thiazol-2-yl i-propyl 843 4-Cl-2-NO₂Ph thiazol-2-yl cyclopropyl 844 4-Cl-2-NO₂Ph thiazol-2-yl CF₃ 845 4-Cl-2-NO₂Ph 4-methylthiazol- H 2-yl 846 4-Cl-2-NO₂Ph 4-methylthiazol- methyl 2-yl 847 4-Cl-2-NO₂Ph 4-methylthiazol- i-propyl 2-yl 848 4-Cl-2-NO₂Ph 4-methylthiazol- cyclopropyl 2-yl 849 4-Cl-2-NO₂Ph 4-methylthiazol- CF₃ 2-yl 850 4-Cl-2-NO₂Ph oxazol-2-yl H 851 4-Cl-2-NO₂Ph oxazol-2-yl methyl 852 4-Cl-2-NO₂Ph oxazol-2-yl i-propyl 853 4-Cl-2-NO₂Ph oxazol-2-yl cyclopropyl 854 4-Cl-2-NO₂Ph oxazol-2-yl CF₃ 855 4-Cl-2-NO₂Ph 4,5-dimethyl- H oxazol-2-yl 856 4-Cl-2-NO₂Ph 4,5-dimethyl- methyl oxazol-2-yl 857 4-Cl-2-NO₂Ph 4,5-dimethyl- i-propyl oxazol-2-yl 858 4-Cl-2-NO₂Ph 4,5-dimethyl- cyclopropyl oxazol-2-yl 859 4-Cl-2-NO₂Ph 4,5-dimethyl- CF₃ oxazol-2-yl 860 4-Cl-2-NO₂Ph 2-oxazolin-2-yl H 861 4-Cl-2-NO₂Ph 2-oxazolin-2-yl methyl 862 4-Cl-2-NO₂Ph 2-oxazolin-2-yl i-propyl 863 4-Cl-2-NO₂Ph 2-oxazolin-2-yl cyclopropyl 864 4-Cl-2-NO₂Ph 2-oxazolin-2-yl CF₃ 865 4-Cl-2-NO₂Ph 4,4-dimethyl-2- H oxazolin-2-yl 866 4-Cl-2-NO₂Ph 4,4-dimethyl-2- methyl oxazolin-2-yl 867 4-Cl-2-NO₂Ph 4,4-dimethyl-2- i-propyl oxazolin-2-yl 868 4-Cl-2-NO₂Ph 4,4-dimethyl-2- cyclopropyl oxazolin-2-yl 869 4-Cl-2-NO₂Ph 4,4-dimethyl-2- CF₃ oxazolin-2-yl 870 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- H 5-yl 871 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- methyl 5-yl 872 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- i-propyl 5-yl 873 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- cyclopropyl 5-yl 874 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- CF₃ 5-yl 875 4-Cl-2-NO₂Ph 3-methyl-1,2,4- H thiadiazol-5-yl 876 4-Cl-2-NO₂Ph 3-methyl-1,2,4- methyl thiadiazol-5-yl 877 4-Cl-2-NO₂Ph 3-methyl-1,2,4- i-propyl thiadiazol-5-yl 878 4-Cl-2-NO₂Ph 3-methyl-1,2,4- cyclopropyl thiadiazol-5-yl 879 4-Cl-2-NO₂Ph 3-methyl-1,2,4- CF₃ thiadiazol-5-yl 880 4-Cl-2-NO₂Ph 3-trifluoromethyl- H 1,2,4-thiadiazol- 5-yl 881 4-Cl-2-NO₂Ph 3-trifluoromethyl- methyl 1,2,4-thiadiazol- 5-yl 882 4-Cl-2-NO₂Ph 3-trifluoromethyl- i-propyl 1,2,4-thiadiazol- 5-yl 883 4-Cl-2-NO₂Ph 3-trifluoromethyl- cyclopropyl 1,2,4-thiadiazol- 5-yl 884 4-Cl-2-NO₂Ph 3-trifluoromethyl- CF₃ 1,2,4-thiadiazol- 5-yl 885 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- H 3-yl 886 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- methyl 3-yl 887 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- i-propyl 3-yl 888 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- cyclopropyl 3-yl 889 4-Cl-2-NO₂Ph 1,2,4-thiadiazol- CF₃ 3-yl 890 4-Cl-2-NO₂Ph 5-methyl-1,2,4- H thiadiazol-3-yl 891 4-Cl-2-NO₂Ph 5-methyl-1,2,4- methyl thiadiazol-3-yl 892 4-Cl-2-NO₂Ph 5-methyl-1,2,4- i-propyl thiadiazol-3-yl 893 4-Cl-2-NO₂Ph 5-methyl-1,2,4- cyclopropyl thiadiazol-3-yl 894 4-Cl-2-NO₂Ph 5-methyl-1,2,4- CF₃ thiadiazol-3-yl 895 4-Cl-2-NO₂Ph 5-trifluoromethyl- H 1,2,4-thiadiazol- 3-yl 896 4-Cl-2-NO₂Ph 5-trifluoromethyl- methyl 1,2,4-thiadiazol- 3-yl 897 4-Cl-2-NO₂Ph 5-trifluoromethyl- i-propyl 1,2,4-thiadiazol- 3-yl 898 4-Cl-2-NO₂Ph 5-trifluoromethyl- cyclopropyl 1,2,4-thiadiazol- 3-yl 899 4-Cl-2-NO₂Ph 5-trifluoromethyl- CF₃ 1,2,4-thiadiazol- 3-yl 900 4-Cl-2-NO₂Ph 1,3,4-thiadiazol- H 2-yl 901 4-Cl-2-NO₂Ph 1,3,4-thiadiazol- methyl 2-yl 902 4-Cl-2-NO₂Ph 1,3,4-thiadiazol- i-propyl 2-yl 903 4-Cl-2-NO₂Ph 1,3,4-thiadiazol- cyclopropyl 2-yl 904 4-Cl-2-NO₂Ph 1,3,4-thiadiazol- CF₃ 2-yl 905 4-Cl-2-NO₂Ph 5-methylsulfonyl- H 1,3,4-thiadiazol- 2-yl 906 4-Cl-2-NO₂Ph 5-methylsulfonyl- methyl 1,3,4-thiadiazol- 2-yl 907 4-Cl-2-NO₂Ph 5-methylsulfonyl- i-propyl 1,3,4-thiadiazol- 2-yl 908 4-Cl-2-NO₂Ph 5-methylsulfonyl- cyclopropyl 1,3,4-thiadiazol- 2-yl 909 4-Cl-2-NO₂Ph 5-methylsulfonyl- CF₃ 1,3,4-thiadiazol- 2-yl 910 4-Cl-2-NO₂Ph 5-methyl-1,3,4- H thiadiazol-2-yl 911 4-Cl-2-NO₂Ph 5-methyl-1,3,4- methyl thiadiazol-2-yl 912 4-Cl-2-NO₂Ph 5-methyl-1,3,4- i-propyl thiadiazol-2-yl 913 4-Cl-2-NO₂Ph 5-methyl-1,3,4- cyclopropyl thiadiazol-2-yl 914 4-Cl-2-NO₂Ph 5-methyl-1,3,4- CF₃ thiadiazol-2-yl 915 4-Cl-2-NO₂Ph benzoxazol-2-yl H 916 4-Cl-2-NO₂Ph benzoxazol-2-yl methyl 917 4-Cl-2-NO₂Ph benzoxazol-2-yl i-propyl 918 4-Cl-2-NO₂Ph benzoxazol-2-yl cyclopropyl 919 4-Cl-2-NO₂Ph benzoxazol-2-yl CF₃ 920 4-Cl-2-NO₂Ph 6-methyl- H benzoxazol-2-yl 921 4-Cl-2-NO₂Ph 6-methyl- methyl benzoxazol-2-yl 922 4-Cl-2-NO₂Ph 6-methyl- i-propyl benzoxazol-2-yl 923 4-Cl-2-NO₂Ph 6-methyl- cyclopropyl benzoxazol-2-yl 924 4-Cl-2-NO₂Ph 6-methyl- CF₃ benzoxazol-2-yl 925 4-Cl-2-NO₂Ph benzothiazol-2-yl H 926 4-Cl-2-NO₂Ph benzothiazol-2-yl methyl 927 4-Cl-2-NO₂Ph benzothiazol-2-yl i-propyl 928 4-Cl-2-NO₂Ph benzothiazol-2-yl cyclopropyl 929 4-Cl-2-NO₂Ph benzothiazol-2-yl CF₃ 930 4-Cl-2-NO₂Ph pyrazol-1-yl H 931 4-Cl-2-NO₂Ph pyrazol-1-yl methyl 932 4-Cl-2-NO₂Ph pyrazol-1-yl i-propyl 933 4-Cl-2-NO₂Ph pyrazol-1-yl cyclopropyl 934 4-Cl-2-NO₂Ph pyrazol-1-yl CF₃ 935 4-Cl-2-NO₂Ph pyrazol-3-yl H 936 4-Cl-2-NO₂Ph pyrazol-3-yl methyl 937 4-Cl-2-NO₂Ph pyrazol-3-yl i-propyl 938 4-Cl-2-NO₂Ph pyrazol-3-yl cyclopropyl 939 4-Cl-2-NO₂Ph pyrazol-3-yl CF₃ 940 4-Cl-2-NO₂Ph 1-methylpyrazol- H 3-yl 941 4-Cl-2-NO₂Ph 1-methylpyrazol- methyl 3-yl 942 4-Cl-2-NO₂Ph 1-methylpyrazol- i-propyl 3-yl 943 4-Cl-2-NO₂Ph 1-methylpyrazol- cyclopropyl 3-yl 944 4-Cl-2-NO₂Ph 1-methylpyrazol- CF₃ 3-yl 945 4-Cl-2-NO₂Ph tetrazol-1-yl H 946 4-Cl-2-NO₂Ph tetrazol-1-yl methyl 947 4-Cl-2-NO₂Ph tetrazol-1-yl i-propyl 948 4-Cl-2-NO₂Ph tetrazol-1-yl cyclopropyl 949 4-Cl-2-NO₂Ph tetrazol-1-yl CF₃ 950 4-Cl-2-NO₂Ph 5-methyltetrazol- H 1-yl 951 4-Cl-2-NO₂Ph 5-methyltetrazol- methyl 1-yl 952 4-Cl-2-NO₂Ph 5-methyltetrazol- i-propyl 1-yl 953 4-Cl-2-NO₂Ph 5-methyltetrazol- cyclopropyl 1-yl 954 4-Cl-2-NO₂Ph 5-methyltetrazol- CF₃ 1-yl 955 4-Cl-2-NO₂Ph tetrazol-2-yl H 956 4-Cl-2-NO₂Ph tetrazol-2-yl methyl 957 4-Cl-2-NO₂Ph tetrazol-2-yl i-propyl 958 4-Cl-2-NO₂Ph tetrazol-2-yl cyclopropyl 959 4-Cl-2-NO₂Ph tetrazol-2-yl CF₃ 960 4-Cl-2-NO₂Ph 5-methyltetrazol- H 2-yl 961 4-Cl-2-NO₂Ph 5-methyltetrazol- methyl 2-yl 962 4-Cl-2-NO₂Ph 5-methyltetrazol- i-propyl 2-yl 963 4-Cl-2-NO₂Ph 5-methyltetrazol- cyclopropyl 2-yl 964 4-Cl-2-NO₂Ph 5-methyltetrazol- CF₃ 2-yl 965 4-Cl-2-NO₂Ph 1-methyltetrazol- H 5-yl 966 4-Cl-2-NO₂Ph 1-methyltetrazol- methyl 5-yl 967 4-Cl-2-NO₂Ph 1-methyltetrazol- i-propyl 5-yl 968 4-Cl-2-NO₂Ph 1-methyltetrazol- cyclopropyl 152 5-yl 969 4-Cl-2-NO₂Ph 1-methyltetrazol- CF₃ 5-yl 970 2-Cl-4-NO₂Ph 2-methyltetrazol- cyclopropyl 137 5-yl 971 4-Cl-2-NO₂Ph 2-methyltetrazol- methyl 5-yl 972 4-Cl-2-NO₂Ph 2-methyltetrazol- i-propyl 5-yl 973 4-Cl-2-NO₂Ph 2-methyltetrazol- cyclopropyl 126 5-yl 974 4-Cl-2-NO₂Ph 2-methyltetrazol- CF₃ 5-yl 975 2,4-(NO₂)₂Ph 2-methyltetrazol- cyclopropyl 144 5-yl 976 4-Cl-2-NO₂Ph pyridin-2-yl methyl 977 4-Cl-2-NO₂Ph pyridin-2-yl i-propyl 978 4-Cl-2-NO₂Ph pyridin-2-yl cyclopropyl 979 4-Cl-2-NO₂Ph pyridin-2-yl CF₃ 980 4-Cl-2-NO₂Ph pyridin-4-yl H 981 4-Cl-2-NO₂Ph pyridin-4-yl methyl 982 4-Cl-2-NO₂Ph pyridin-4-yl i-propyl 983 4-Cl-2-NO₂Ph pyridin-4-yl cyclopropyl 984 4-Cl-2-NO₂Ph pyridin-4-yl CF₃ 985 4-Cl-2-NO₂Ph pyridin-3-yl H 986 4-Cl-2-NO₂Ph pyridin-3-yl methyl 987 4-Cl-2-NO₂Ph pyridin-3-yl i-propyl 988 4-Cl-2-NO₂Ph pyridin-3-yl cyclopropyl 989 4-Cl-2-NO₂Ph pyridin-3-yl CF₃ 990 4-Cl-2-NO₂Ph 3-nitropyridin- H 4-yl 991 4-Cl-2-NO₂Ph 3-nitropyridin- methyl 4-yl 992 4-Cl-2-NO₂Ph 3-nitropyridin- i-propyl 4-yl 993 4-Cl-2-NO₂Ph 3-nitropyridin- cyclopropyl 4-yl 994 4-Cl-2-NO₂Ph 3-nitropyridin- CF₃ 4-yl 995 4-Cl-2-NO₂Ph 5-cyanopyridin- H 2-yl 996 4-Cl-2-NO₂Ph 5-cyanopyridin- methyl 2-yl 997 4-Cl-2-NO₂Ph 5-cyanopyridin- i-propyl 2-yl 998 4-Cl-2-NO₂Ph 5-cyanopyridin- cyclopropyl 2-yl 999 4-Cl-2-NO₂Ph 5-cyanopyridin- CF₃ 2-yl 1000 4-Cl-2-NO₂Ph 5-trifluoro- H methylpyridin- 2-yl 1001 4-Cl-2-NO₂Ph 5-trifluoro- methyl methylpyridin- 2-yl 1002 4-Cl-2-NO₂Ph 5-trifluoro- i-propyl methylpyridin- 2-yl 1003 4-Cl-2-NO₂Ph 5-trifluoro- cyclopropyl methylpyridin- 2-yl 1004 4-Cl-2-NO₂Ph 5-trifluoro- CF₃ methylpyridin- 2-yl 1005 4-Cl-2-NO₂Ph pyrimidin-2-yl H 1006 4-Cl-2-NO₂Ph pyrimidin-2-yl methyl 1007 4-Cl-2-NO₂Ph pyrimidin-2-yl i-propyl 1008 4-Cl-2-NO₂Ph pyrimidin-2-yl cyclopropyl 1009 4-Cl-2-NO₂Ph pyrimidin-2-yl CF₃ 1010 4-Cl-2-NO₂Ph pyrimidin-4-yl H 1011 4-Cl-2-NO₂Ph pyrimidin-4-yl methyl 1012 4-Cl-2-NO₂Ph pyrimidin-4-yl i-propyl 1013 4-Cl-2-NO₂Ph pyrimidin-4-yl cyclopropyl 1014 4-Cl-2-NO₂Ph pyrimidin-4-yl CF₃ 1015 4-Cl-2-NO₂Ph 6-chloro- methyl pyrimidin-4-yl 1016 4-Cl-2-NO₂Ph 6-chloro- i-propyl pyrimidin-4-yl 1017 4-Cl-2-NO₂Ph 6-chloro- cyclopropyl pyrimidin-4-yl 1018 4-Cl-2-NO₂Ph 6-chloro- CF₃ pyrimidin-4-yl 1019 2,4-(Cl)₂Ph 1-methyltetrazol- t-butil 124 5-yl 1020 4-Cl-2-NO₂Ph pyridazin-3-yl methyl 1021 4-Cl-2-NO₂Ph pyridazin-3-yl i-propyl 1022 4-Cl-2-NO₂Ph pyridazin-3-yl cyclopropyl 1023 4-Cl-2-NO₂Ph pyridazin-3-yl CF₃ 1024 4-Cl-2-NO₂Ph 6-chloro- methyl pyridazin-3-yl 1025 4-Cl-2-NO₂Ph 6-chloro- i-propyl pyridazin-3-yl 1026 4-Cl-2-NO₂Ph 6-chloro- cyclopropyl pyridazin-3-yl 1027 4-Cl-2-NO₂Ph 6-chloro- CF₃ pyridazin-3-yl 1028 4-Cl-2-NO₂Ph pyrazin-2-yl methyl 1029 4-Cl-2-NO₂Ph pyrazin-2-yl i-propyl 1030 4-Cl-2-NO₂Ph pyrazin-2-yl cyclopropyl 1031 4-Cl-2-NO₂Ph pyrazin-2-yl CF₃ 1032 4-Cl-2-NO₂Ph triazin-2-yl methyl 1033 4-Cl-2-NO₂Ph triazin-2-yl i-propyl 1034 4-Cl-2-NO₂Ph triazin-2-yl cyclopropyl 1035 4-Cl-2-NO₂Ph triazin-2-yl CF₃ 1036 4-Cl-2-NO₂Ph quinolin-2-yl methyl 1037 4-Cl-2-NO₂Ph quinolin-2-yl i-propyl 1038 4-Cl-2-NO₂Ph quinolin-2-yl cyclopropyl 1039 4-Cl-2-NO₂Ph quinolin-2-yl CF₃ 1040 4-Cl-2-NO₂Ph 4,4,6-trimethyl- H 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1041 4-Cl-2-NO₂Ph 4,4,6-trimethyl- methyl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1042 4-Cl-2-NO₂Ph 4,4,6-trimethyl- i-propyl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1043 4-Cl-2-NO₂Ph 4,4,6-trimethyl- cyclopropyl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1044 4-Cl-2-NO₂Ph 4,4,6-trimethyl- CF₃ 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1045 4-Cl-2-NO₂Ph 2-oxazolidinon- H 3-yl 1046 4-Cl-2-NO₂Ph 2-oxazolidinon- methyl 3-yl 1047 4-Cl-2-NO₂Ph 2-oxazolidinon- i-propyl 3-yl 1048 4-Cl-2-NO₂Ph 2-oxazolidinon- cyclopropyl 3-yl 1049 4-Cl-2-NO₂Ph 2-oxazolidinon- CF₃ 3-yl 1050 4-Cl-2-NO₂Ph 2-pyrrolidinon- methyl 1-yl 1051 4-Cl-2-NO₂Ph 2-pyrrolidinon- i-propyl 1-yl 1052 4-Cl-2-NO₂Ph 2-pyrrolidinon- cyclopropyl 1-yl 1053 4-Cl-2-NO₂Ph 2-pyrrolidinon- CF₃ 1-yl 1054 4-Cl-2-NO₂Ph 3-methylisoxazol- methyl 5-yl 1055 4-Cl-2-NO₂Ph 3-methylisoxazol- i-propyl 5-yl 1056 4-Cl-2-NO₂Ph 3-methylisoxazol- cyclopropyl 5-yl 1057 4-Cl-2-NO₂Ph 3-methylisoxazol- CF₃ 5-yl 1058 4-Cl-2-NO₂Ph 2-NO₂-4- H SO₂MePh 1059 4-Cl-2-NO₂Ph 2-NO₂-4- methyl SO₂MePh 1060 4-Cl-2-NO₂Ph 2-NO₂-4- i-propyl SO₂MePh 1061 4-Cl-2-NO₂Ph 2-NO₂-4- cyclopropyl SO₂MePh 1062 4-Cl-2-NO₂Ph 2-NO₂-4- CF₃ SO₂MePh 1063 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePH H 1064 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePH methyl 1065 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePH i-propyl 1066 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePH cyclopropyl 1067 4-Cl-2-NO₂Ph 2-Cl-4-SO₂MePH CF₃ 1068 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph H 1069 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph methyl 1070 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph i-propyl 1071 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph cyclopropyl 1072 4-Cl-2-NO₂Ph 2-NO₂-4-CF₃Ph CF₃ 1073 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh H 1074 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh methyl 1075 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh i-propyl 1076 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh cyclopropyl 1077 4-Cl-2-NO₂Ph 2-NO₂-4-ClPh CF₃ 1078 4-Cl-2-NO₂Ph 2-Cl-4-NO₂PH H 1079 4-Cl-2-NO₂Ph 2-Cl-4-NO₂PH methyl 1080 4-Cl-2-NO₂Ph 2-Cl-4-NO₂PH i-propyl 1081 4-Cl-2-NO₂Ph 2-Cl-4-NO₂PH cyclopropyl 1082 4-Cl-2-NO₂Ph 2-Cl-4-NO₂PH CF₃ 1083 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph H 1084 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph methyl 1085 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph i-propyl 1086 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph cyclopropyl 1087 4-Cl-2-NO₂Ph 2,4-(NO₂)₂Ph CF₃ 1088 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph H 1089 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph methyl 1090 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph i-propyl 1091 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph cyclopropyl 1092 4-Cl-2-NO₂Ph 4-F-3-NO₂Ph CF₃ 1093 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph H 1094 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph methyl 1095 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph i-propyl 1096 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph cyclopropyl 1097 4-Cl-2-NO₂Ph 3,5-(CF₃)₂Ph CF₃ 1098 4-Cl-2-NO₂Ph 2-SO₂Me-4- H CF₃Ph 1099 4-Cl-2-NO₂Ph 2-SO₂Me-4- methyl CF₃Ph 1100 4-Cl-2-NO₂Ph 2-SO₂Me-4- i-propyl CF₃Ph 1101 4-Cl-2-NO₂Ph 2-SO₂Me-4- cyclopropyl CF₃Ph 1102 4-Cl-2-NO₂Ph 2-SO₂Me-4- CF₃ CF₃Ph 1103 2-SO₂Me-4- 1,2,4-oxadiazol-5- H CF₃Ph yl 1104 2-SO₂Me-4- 1,2,4-oxadiazol-5- methyl CF₃Ph yl 1105 2-SO₂Me-4- 1,2,4-oxadiazol-5- i-propyl CF₃Ph yl 1106 2-SO₂Me-4- 1,2,4-oxadiazol-5- cyclopropyl CF₃Ph yl 1107 2-SO₂Me-4- 1,2,4-oxadiazol-5- CF₃ CF₃Ph yl 1108 2-SO₂Me-4- 3-methyl-1,2,4- H CF₃Ph oxadiazol-5-yl 1109 2-SO₂Me-4- 3-methyl-1,2,4- methyl CF₃Ph oxadiazol-5-yl 1110 2-SO₂Me-4- 3-methyl-1,2,4- i-propyl CF₃Ph oxadiazol-5-yl 1111 2-SO₂Me-4- 3-methyl-1,2,4- cyclopropyl CF₃Ph oxadiazol-5-yl 1112 2-SO₂Me-4- 3-methyl-1,2,4- CF₃ CF₃Ph oxadiazol-5-yl 1113 2-SO₂Me-4- 3-trifluoromethyl- H CF₃Ph 1,2,4-oxadiazol- 5-yl 1114 2-SO₂Me-4- 3-trifluoromethyl- methyl CF₃Ph 1,2,4-oxadiazol- 5-yl 1115 2-SO₂Me-4- 3-trifluoromethyl- i-propyl CF₃Ph 1,2,4-oxadiazol- 5-yl 1116 2-SO₂Me-4- 3-trifluoromethyl- cyclopropyl CF₃Ph 1,2,4-oxadiazol- 5-yl 1117 2-SO₂Me-4- 3-trifluoromethyl- CF₃ CF₃Ph 1,2,4-oxadiazol- 5-yl 1118 2-SO₂Me-4- 1,2,4-oxadiazol-3- H CF₃Ph yl 1119 2-SO₂Me-4- 1,2,4-oxadiazol-3- methyl CF₃Ph yl 1120 2-SO₂Me-4- 1,2,4-oxadiazol-3- i-propyl CF₃Ph yl 1121 2-SO₂Me-4- 1,2,4-oxadiazol-3- cyclopropyl CF₃Ph yl 1122 2-SO₂Me-4- 1,2,4-oxadiazol-3- CF₃ CF₃Ph yl 1123 2-SO₂Me-4- 5-methyl-1,2,4- H CF₃Ph oxadiazol-3-yl 1124 2-SO₂Me-4- 5-methyl-1,2,4- methyl CF₃Ph oxadiazol-3-yl 1125 2-SO₂Me-4- 5-methyl-1,2,4- i-propyl CF₃Ph oxadiazol-3-yl 1126 2-SO₂Me-4- 5-methyl-1,2,4- cyclopropyl CF₃Ph oxadiazol-3-yl 1127 2-SO₂Me-4- 5-methyl-1,2,4- CF₃ CF₃Ph oxadiazol-3-yl 1128 2-SO₂Me-4- 5-trifluoromethyl- H CF₃Ph 1,2,4-oxadiazol- 3-yl 1129 2-SO₂Me-4- 5-trifluoromethyl- methyl CF₃Ph 1,2,4-oxadiazol- 3-yl 1130 2-SO₂Me-4- 5-trifluoromethyl- i-propyl CF₃Ph 1,2,4-oxadiazol- 3-yl 1131 2-SO₂Me-4- 5-trifluoromethyl- cyclopropyl CF₃Ph 1,2,4-oxadiazol- 3-yl 1132 2-SO₂Me-4- 5-trifluoromethyl- CF₃ CF₃Ph 1,2,4-oxadiazol- 3-yl 1133 2-SO₂Me-4- 5-chloro-1,2,4- H CF₃Ph oxadiazol-3-yl 1134 2-SO₂Me-4- 5-chloro-1,2,4- methyl CF₃Ph oxadiazol-3-yl 1135 2-SO₂Me-4- 5-chloro-1,2,4- i-propyl CF₃Ph oxadiazol-3-yl 1136 2-SO₂Me-4- 5-chloro-1,2,4- cyclopropyl CF₃Ph oxadiazol-3-yl 1137 2-SO₂Me-4- 5-chloro-1,2,4- CF₃ CF₃Ph oxadiazol-3-yl 1138 2-SO₂Me-4- 1,3,4-oxadiazol-2- H CF₃Ph yl 1139 2-SO₂Me-4- 1,3,4-oxadiazol-2- methyl CF₃Ph yl 1140 2-SO₂Me-4- 1,3,4-oxadiazol-2- i-propyl CF₃Ph yl 1141 2-SO₂Me-4- 1,3,4-oxadiazol-2- cyclopropyl CF₃Ph yl 1142 2-SO₂Me-4- 1,3,4-oxadiazol-2- CF₃ CF₃Ph yl 1143 2-SO₂Me-4- 5-methylsulfonyl- H CF₃Ph 1,3,4-oxadiazol- 2-yl 1144 2-SO₂Me-4- 5-methylsulfonyl- methyl CF₃Ph 1,3,4-oxadiazol- 2-yl 1145 2-SO₂Me-4- 5-methylsulfonyl- i-propyl CF₃Ph 1,3,4-oxadiazol- 2-yl 1146 2-SO₂Me-4- 5-methylsulfonyl- cyclopropyl CF₃Ph 1,3,4-oxadiazol- 2-yl 1147 2-SO₂Me-4- 5-methylsulfonyl- CF₃ CF₃Ph 1,3,4-oxadiazol- 2-yl 1148 2-SO₂Me-4- 5-methyl-1,3,4- H CF₃Ph oxadiazol-2-yl 1149 2-SO₂Me-4- 5-methyl-1,3,4- methyl CF₃Ph oxadiazol-2-yl 1150 2-SO₂Me-4- 5-methyl-1,3,4- i-propyl CF₃Ph oxadiazol-2-yl 1151 2-SO₂Me-4- 5-methyl-1,3,4- cyclopropyl CF₃Ph oxadiazol-2-yl 1152 2-SO₂Me-4- 5-methyl-1,3,4- CF₃ CF₃Ph oxadiazol-2-yl 1153 2-SO₂Me-4- 5-trifluoromethyl- H CF₃Ph 1,3,4-oxadiazol- 2-yl 1154 2-SO₂Me-4- 5-trifluoromethyl- methyl CF₃Ph 1,3,4-oxadiazol- 2-yl 1155 2-SO₂Me-4- 5-trifluoromethyl- i-propyl CF₃Ph 1,3,4-oxadiazol- 2-yl 1156 2-SO₂Me-4- 5-trifluoromethyl- cyclopropyl CF₃Ph 1,3,4-oxadiazol- 2-yl 1157 2-SO₂Me-4- 5-trifluoromethyl- CF₃ CF₃Ph 1,3,4-oxadiazol- 2-yl 1158 2-SO₂Me-4- 1,2,3-triazol-4-yl H CF₃Ph 1159 2-SO₂Me-4- 1,2,3-triazol-4-yl methyl CF₃Ph 1160 2-SO₂Me-4- 1,2,3-triazol-4-yl i-propyl CF₃Ph 1161 2-SO₂Me-4- 1,2,3-triazol-4-yl cyclopropyl CF₃Ph 1162 2-SO₂Me-4- 1,2,3-triazol-4-yl CF₃ CF₃Ph 1163 2-SO₂Me-4- 1-methyl-1,2,3- H CF₃Ph triazol-4-yl 1164 2-SO₂Me-4- 1-methyl-1,2,3- methyl CF₃Ph triazol-4-yl 1165 2-SO₂Me-4- 1-methyl-1,2,3- i-propyl CF₃Ph triazol-4-yl 1166 2-SO₂Me-4- 1-methyl-1,2,3- cyclopropyl CF₃Ph triazol-4-yl 1167 2-SO₂Me-4- 1-methyl-1,2,3- CF₃ CF₃Ph triazol-4-yl 1168 2-SO₂Me-4- 2-methyl-1,2,3- H CF₃Ph triazol-4-yl 1169 2-SO₂Me-4- 2-methyl-1,2,3- methyl CF₃Ph triazol-4-yl 1170 2-SO₂Me-4- 2-methyl-1,2,3- i-propyl CF₃Ph triazol-4-yl 1171 2-SO₂Me-4- 2-methyl-1,2,3- cyclopropyl CF₃Ph triazol-4-yl 1172 2-SO₂Me-4- 2-methyl-1,2,3- CF₃ CF₃Ph triazol-4-yl 1173 2-SO₂Me-4- 1,2,3-triazol-1-yl H CF₃Ph 1174 2-SO₂Me-4- 1,2,3-triazol-1-yl methyl CF₃Ph 1175 2-SO₂Me-4- 1,2,3-triazol-1-yl i-propyl CF₃Ph 1176 2-SO₂Me-4- 1,2,3-triazol-1-yl cyclopropyl CF₃Ph 1177 2-SO₂Me-4- 1,2,3-triazol-1-yl CF₃ CF₃Ph 1178 2-SO₂Me-4- 1,2,3-triazol-2-yl H CF₃Ph 1179 2-SO₂Me-4- 1,2,3-triazol-2-yl methyl CF₃Ph 1180 2-SO₂Me-4- 1,2,3-triazol-2-yl i-propyl CF₃Ph 1181 2-SO₂Me-4- 1,2,3-triazol-2-yl cyclopropyl CF₃Ph 1182 2-SO₂Me-4- 1,2,3-triazol-2-yl CF₃ CF₃Ph 1183 2-SO₂Me-4- 1,2,4-triazol-1-yl H CF₃Ph 1184 2-SO₂Me-4- 1,2,4-triazol-1-yl methyl CF₃Ph 1185 2-SO₂Me-4- 1,2,4-triazol-1-yl i-propyl CF₃Ph 1186 2-SO₂Me-4- 1,2,4-triazol-1-yl cyclopropyl CF₃Ph 1187 2-SO₂Me-4- 1,2,4-triazol-1-yl CF₃ CF₃Ph 1188 2-SO₂Me-4- imidazol-2-yl H CF₃Ph 1189 2-SO₂Me-4- imidazol-2-yl methyl CF₃Ph 1190 2-SO₂Me-4- imidazol-2-yl i-propyl CF₃Ph 1191 2-SO₂Me-4- imidazol-2-yl cyclopropyl CF₃Ph 1192 2-SO₂Me-4- imidazol-2-yl CF₃ CF₃Ph 1193 2-SO₂Me-4- imidazol-1-yl H CF₃Ph 1194 2-SO₂Me-4- imidazol-1-yl methyl CF₃Ph 1195 2-SO₂Me-4- imidazol-1-yl i-propyl CF₃Ph 1196 2-SO₂Me-4- imidazol-1-yl cyclopropyl CF₃Ph 1197 2-SO₂Me-4- imidazol-1-yl CF₃ CF₃Ph 1198 2-SO₂Me-4- imidazol-4-yl H CF₃Ph 1199 2-SO₂Me-4- imidazol-4-yl methyl CF₃Ph 1200 2-SO₂Me-4- imidazol-4-yl i-propyl CF₃Ph 1201 2-SO₂Me-4- imidazol-4-yl cyclopropyl CF₃Ph 1202 2-SO₂Me-4- imidazol-4-yl CF₃ CF₃Ph 1203 2-SO₂Me-4- thiazol-2-yl H CF₃Ph 1204 2-SO₂Me-4- thiazol-2-yl methyl CF₃Ph 1205 2-SO₂Me-4- thiazol-2-yl i-propyl CF₃Ph 1206 2-SO₂Me-4- thiazol-2-yl cyclopropyl CF₃Ph 1207 2-SO₂Me-4- thiazol-2-yl CF₃ CF₃Ph 1208 2-SO₂Me-4- methylthiazol-2-yl H CF₃Ph 1209 2-SO₂Me-4- methylthiazol-2-yl methyl CF₃Ph 1210 2-SO₂Me-4- methylthiazol-2-yl i-propyl CF₃Ph 1211 2-SO₂Me-4- methylthiazol-2-yl cyclopropyl CF₃Ph 1212 2-SO₂Me-4- methylthiazol-2-yl CF₃ CF₃Ph 1213 2-SO₂Me-4- oxazol-2-yl H CF₃Ph 1214 2-SO₂Me-4- oxazol-2-yl methyl CF₃Ph 1215 2-SO₂Me-4- oxazol-2-yl i-propyl CF₃Ph 1216 2-SO₂Me-4- oxazol-2-yl cyclopropyl CF₃Ph 1217 2-SO₂Me-4- oxazol-2-yl CF₃ CF₃Ph 1218 2-SO₂Me-4- 4,5-dimethyl- H CF₃Ph oxazol-2-yl 1219 2-SO₂Me-4- 4,5-dimethyl- methyl CF₃Ph oxazol-2-yl 1220 2-SO₂Me-4- 4,5-dimethyl- i-propyl CF₃Ph oxazol-2-yl 1221 2-SO₂Me-4- 4,5-dimethyl- cyclopropyl CF₃Ph oxazol-2-yl 1222 2-SO₂Me-4- 4,5-dimethyl- CF₃ CF₃Ph oxazol-2-yl 1223 2-SO₂Me-4- 2-oxazolin-2-yl H CF₃Ph 1224 2-SO₂Me-4- 2-oxazolin-2-yl methyl CF₃Ph 1225 2-SO₂Me-4- 2-oxazolin-2-yl i-propyl CF₃Ph 1226 2-SO₂Me-4- 2-oxazolin-2-yl cyclopropyl CF₃Ph 1227 2-SO₂Me-4- 2-oxazolin-2-yl CF₃ CF₃Ph 1228 2-SO₂Me-4- 4,4-dimethyl-2- H CF₃Ph oxazolin-2-yl 1229 2-SO₂Me-4- 4,4-dimethyl-2- methyl CF₃Ph oxazolin-2-yl 1230 2-SO₂Me-4- 4,4-dimethyl-2- i-propyl CF₃Ph oxazolin-2-yl 1231 2-SO₂Me-4- 4,4-dimethyl-2- cyclopropyl CF₃Ph oxazolin-2-yl 1232 2-SO₂Me-4- 4,4-dimethyl-2- CF₃ CF₃Ph oxazolin-2-yl 1233 2-SO₂Me-4- 1,2,4-thiadiazol- H CF₃Ph 5-yl 1234 2-SO₂Me-4- 1,2,4-thiadiazol- methyl CF₃Ph 5-yl 1235 2-SO₂Me-4- 1,2,4-thiadiazol- i-propyl CF₃Ph 5-yl 1236 2-SO₂Me-4- 1,2,4-thiadiazol- cyclopropyl CF₃Ph 5-yl 1237 2-SO₂Me-4- 1,2,4-thiadiazol- CF₃ CF₃Ph 5-yl 1238 2-SO₂Me-4- 3-methyl-1,2,4- H CF₃Ph thiadiazol-5-yl 1239 2-SO₂Me-4- 3-methyl-1,2,4- methyl CF₃Ph thiadiazol-5-yl 1240 2-SO₂Me-4- 3-methyl-1,2,4- i-propyl CF₃Ph thiadiazol-5-yl 1241 2-SO₂Me-4- 3-methyl-1,2,4- cyclopropyl CF₃Ph thiadiazol-5-yl 1242 2-SO₂Me-4- 3-methyl-1,2,4- CF₃ CF₃Ph thiadiazol-5-yl 1243 2-SO₂Me-4- 3-trifluoromethyl- H CF₃Ph 1,2,4-thiadiazol- 5-yl 1244 2-SO₂Me-4- 3-trifluoromethyl- methyl CF₃Ph 1,2,4-thiadiazol- 5-yl 1245 2-SO₂Me-4- 3-trifluoromethyl- i-propyl CF₃Ph 1,2,4-thiadiazol- 5-yl 1246 2-SO₂Me-4- 3-trifluoromethyl- cyclopropyl CF₃Ph 1,2,4-thiadiazol- 5-yl 1247 2-SO₂Me-4- 3-trifluoromethyl- CF₃ CF₃Ph 1,2,4-thiadiazol- 5-yl 1248 2-SO₂Me-4- 1,2,4-thiadiazol- H CF₃Ph 3-yl 1249 2-SO₂Me-4- 1,2,4-thiadiazol- methyl CF₃Ph 3-yl 1250 2-SO₂Me-4- 1,2,4-thiadiazol- i-propyl CF₃Ph 3-yl 1251 2-SO₂Me-4- 1,2,4-thiadiazol- cyclopropyl CF₃Ph 3-yl 1252 2-SO₂Me-4- 1,2,4-thiadiazol- CF₃ CF₃Ph 3-yl 1253 2-SO₂Me-4- 5-methyl-1,2,4- H CF₃Ph thiadiazol-3-yl 1254 2-SO₂Me-4- 5-methyl-1,2,4- methyl CF₃Ph thiadiazol-3-yl 1255 2-SO₂Me-4- 5-methyl-1,2,4- i-propyl CF₃Ph thiadiazol-3-yl 1256 2-SO₂Me-4- 5-methyl-1,2,4- cyclopropyl CF₃Ph thiadiazol-3-yl 1257 2-SO₂Me-4- 5-methyl-1,2,4- CF₃ CF₃Ph thiadiazol-3-yl 1258 2-SO₂Me-4- 5-trifluoromethyl- H CF₃Ph 1,2,4-thiadiazol- 3-yl 1259 2-SO₂Me-4- 5-trifluoromethyl- methyl CF₃Ph 1,2,4-thiadiazol- 3-yl 1260 2-SO₂Me-4- 5-trifluoromethyl- i-propyl CF₃Ph 1,2,4-thiadiazol- 3-yl 1261 2-SO₂Me-4- 5-trifluoromethyl- cyclopropyl CF₃Ph 1,2,4-thiadiazol- 3-yl 1262 2-SO₂Me-4- 5-trifluoromethyl- CF₃ CF₃Ph 1,2,4-thiadiazol- 3-yl 1263 2-SO₂Me-4- 1,3,4-thiadiazol- H CF₃Ph 2-yl 1264 2-SO₂Me-4- 1,3,4-thiadiazol- methyl CF₃Ph 2-yl 1265 2-SO₂Me-4- 1,3,4-thiadiazol- i-propyl CF₃Ph 2-yl 1266 2-SO₂Me-4- 1,3,4-thiadiazol- cyclopropyl CF₃Ph 2-yl 1267 2-SO₂Me-4- 1,3,4-thiadiazol- CF₃ CF₃Ph 2-yl 1268 2-SO₂Me-4- 5-methylsulfonyl- H CF₃Ph 1,3,4-thiadiazol- 2-yl 1269 2-SO₂Me-4- 5-methylsulfonyl- methyl CF₃Ph 1,3,4-thiadiazol- 2-yl 1270 2-SO₂Me-4- 5-methylsulfonyl- i-propyl CF₃Ph 1,3,4-thiadiazol- 2-yl 1271 2-SO₂Me-4- 5-methylsulfonyl- cyclopropyl CF₃Ph 1,3,4-thiadiazol- 2-yl 1272 2-SO₂Me-4- 5-methylsulfonyl- CF₃ CF₃Ph 1,3,4-thiadiazol- 2-yl 1273 2-SO₂Me-4- 5-methyl-1,3,4- H CF₃Ph thiadiazol-2-yl 1274 2-SO₂Me-4- 5-methyl-1,3,4- methyl CF₃Ph thiadiazol-2-yl 1275 2-SO₂Me-4- 5-methyl-1,3,4- i-propyl CF₃Ph thiadiazol-2-yl 1276 2-SO₂Me-4- 5-methyl-1,3,4- cyclopropyl CF₃Ph thiadiazol-2-yl 1277 2-SO₂Me-4- 5-methyl-1,3,4- CF₃ CF₃Ph thiadiazol-2-yl 1278 2-SO₂Me-4- benzoxazol-2-yl H CF₃Ph 1279 2-SO₂Me-4- benzoxazol-2-yl methyl CF₃Ph 1280 2-SO₂Me-4- benzoxazol-2-yl i-propyl CF₃Ph 1281 2-SO₂Me-4- benzoxazol-2-yl cyclopropyl CF₃Ph 1282 2-SO₂Me-4- benzoxazol-2-yl CF₃ CF₃Ph 1283 2-SO₂Me-4- 6-methyl- H CF₃Ph benzoxazol-2-yl 1284 2-SO₂Me-4- 6-methyl- methyl CF₃Ph benzoxazol-2-yl 1285 2-SO₂Me-4- 6-methyl- i-propyl CF₃Ph benzoxazol-2-yl 1286 2-SO₂Me-4- 6-methyl- cyclopropyl CF₃Ph benzoxazol-2-yl 1287 2-SO₂Me-4- 6-methyl- CF₃ CF₃Ph benzoxazol-2-yl 1288 2-SO₂Me-4- benzothiazol-2-yl H CF₃Ph 1289 2-SO₂Me-4- benzothiazol-2-yl methyl CF₃Ph 1290 2-SO₂Me-4- benzothiazol-2-yl i-propyl CF₃Ph 1291 2-SO₂Me-4- benzothiazol-2-yl cyclopropyl CF₃Ph 1292 2-SO₂Me-4- benzothiazol-2-yl CF₃ CF₃Ph 1293 2-SO₂Me-4- pyrazol-1-yl H CF₃Ph 1294 2-SO₂Me-4- pyrazol-1-yl methyl CF₃Ph 1295 2-SO₂Me-4- pyrazol-1-yl i-propyl CF₃Ph 1296 2-SO₂Me-4- pyrazol-1-yl cyclopropyl CF₃Ph 1297 2-SO₂Me-4- pyrazol-1-yl CF₃ CF₃Ph 1298 2-SO₂Me-4- pyrazol-3-yl H CF₃Ph 1299 2-SO₂Me-4- pyrazol-3-yl methyl CF₃Ph 1300 2-SO₂Me-4- pyrazol-3-yl i-propyl CF₃Ph 1301 2-SO₂Me-4- pyrazol-3-yl cyclopropyl CF₃Ph 1302 2-SO₂Me-4- pyrazol-3-yl CF₃ CF₃Ph 1303 2-SO₂Me-4- 1-methyl-pyrazol-3-yl H CF₃Ph 3-yl 1304 2-SO₂Me-4- 1-methyl-pyrazol-3-yl methyl CF₃Ph 3-yl 1305 2-SO₂Me-4- 1-methyl-pyrazol-3-yl i-propyl CF₃Ph 3-yl 1306 2-SO₂Me-4- 1-methyl-pyrazol-3-yl cyclopropyl CF₃Ph 3-yl 1307 2-SO₂Me-4- 1-methyl-pyrazol-3-yl CF₃ CF₃Ph 3-yl 1308 2-SO₂Me-4- tetrazol-1-yl H CF₃Ph 1309 2-SO₂Me-4- tetrazol-1-yl methyl CF₃Ph 1310 2-SO₂Me-4- tetrazol-1-yl i-propyl CF₃Ph 1311 2-SO₂Me-4- tetrazol-1-yl cyclopropyl CF₃Ph 1312 2-SO₂Me-4- tetrazol-1-yl CF₃ CF₃Ph 1313 2-SO₂Me-4- 5-methyltetrazol- H CF₃Ph 1-yl 1314 2-SO₂Me-4- 5-methyltetrazol- methyl CF₃Ph 1-yl 1315 2-SO₂Me-4- 5-methyltetrazol- i-propyl CF₃Ph 1-yl 1316 2-SO₂Me-4- 5-methyltetrazol- cyclopropyl CF₃Ph 1-yl 1317 2-SO₂Me-4- 5-methyltetrazol- CF₃ CF₃Ph 1-yl 1318 2-SO₂Me-4- tetrazol-2-yl H CF₃Ph 1319 2-SO₂Me-4- tetrazol-2-yl methyl CF₃Ph 1320 2-SO₂Me-4- tetrazol-2-yl i-propyl CF₃Ph 1321 2-SO₂Me-4- tetrazol-2-yl cyclopropyl CF₃Ph 1322 2-SO₂Me-4- tetrazol-2-yl CF₃ CF₃Ph 1323 2-SO₂Me-4- 5-methyltetrazol- H CF₃Ph 2-yl 1324 2-SO₂Me-4- 5-methyltetrazol- methyl CF₃Ph 2-yl 1325 2-SO₂Me-4- 5-methyltetrazol- i-propyl CF₃Ph 2-yl 1326 2-SO₂Me-4- 5-methyltetrazol- cyclopropyl CF₃Ph 2-yl 1327 2-SO₂Me-4- 5-methyltetrazol- CF₃ CF₃Ph 2-yl 1328 2-SO₂Me-4- 1-methyltetrazol- H CF₃Ph 5-yl 1329 2-SO₂Me-4- 1-methyltetrazol- methyl CF₃Ph 5-yl 1330 2-SO₂Me-4- 1-methyltetrazol- i-propyl CF₃Ph 5-yl 1331 2-SO₂Me-4- 1-methyltetrazol- cyclopropyl CF₃Ph 5-yl 1332 2-SO₂Me-4- 1-methyltetrazol- CF₃ CF₃Ph 5-yl 1333 2-SO₂Me-4- 2-methyltetrazol- H CF₃Ph 5-yl 1334 2-SO₂Me-4- 2-methyltetrazol- methyl CF₃Ph 5-yl 1335 2-SO₂Me-4- 2-methyltetrazol- i-propyl CF₃Ph 5-yl 1336 2-SO₂Me-4- 2-methyltetrazol- cyclopropyl 157 CF₃Ph 5-yl 1337 2-SO₂Me-4- 2-methyltetrazol- CF₃ CF₃Ph 5-yl 1338 2-SO₂Me-4- pyridin-2-yl H CF₃Ph 1339 2-SO₂Me-4- pyridin-2-yl methyl CF₃Ph 1340 2-SO₂Me-4- pyridin-2-yl i-propyl CF₃Ph 1341 2-SO₂Me-4- pyridin-2-yl cyclopropyl CF₃Ph 1342 2-SO₂Me-4- pyridin-2-yl CF₃ CF₃Ph 1343 2-SO₂Me-4- pyridin-4-yl H CF₃Ph 1344 2-SO₂Me-4- pyridin-4-yl methyl CF₃Ph 1345 2-SO₂Me-4- pyridin-4-yl i-propyl CF₃Ph 1346 2-SO₂Me-4- pyridin-4-yl cyclopropyl CF₃Ph 1347 2-SO₂Me-4- pyridin-4-yl CF₃ CF₃Ph 1348 2-SO₂Me-4- pyridin-3-yl H CF₃Ph 1349 2-SO₂Me-4- pyridin-3-yl methyl CF₃Ph 1350 2-SO₂Me-4- pyridin-3-yl i-propyl CF₃Ph 1351 2-SO₂Me-4- pyridin-3-yl cyclopropyl CF₃Ph 1352 2-SO₂Me-4- pyridin-3-yl CF₃ CF₃Ph 1353 2-SO₂Me-4- 3-nitropyridin- H CF₃Ph 4-yl 1354 2-SO₂Me-4- 3-nitropyridin- methyl CF₃Ph 4-yl 1355 2-SO₂Me-4- 3-nitropyridin- i-propyl CF₃Ph 4-yl 1356 2-SO₂Me-4- 3-nitropyridin- cyclopropyl CF₃Ph 4-yl 1357 2-SO₂Me-4- 3-nitropyridin- CF₃ CF₃Ph 4-yl 1358 2-SO₂Me-4- 5-cyanopyridin- H CF₃Ph 2-yl 1359 2-SO₂Me-4- 5-cyanopyridin- methyl CF₃Ph 2-yl 1360 2-SO₂Me-4- 5-cyanopyridin- i-propyl CF₃Ph 2-yl 1361 2-SO₂Me-4- 5-cyanopyridin- cyclopropyl CF₃Ph 2-yl 1362 2-SO₂Me-4- 5-cyanopyridin- CF₃ CF₃Ph 2-yl 1363 2-SO₂Me-4- 5-trifluoro- H CF₃Ph methylpyridin- 2-yl 1364 2-SO₂Me-4- 5-trifluoro- methyl CF₃Ph methylpyridin- 2-yl 1365 2-SO₂Me-4- 5-trifluoro- i-propyl CF₃Ph methylpyridin- 2-yl 1366 2-SO₂Me-4- 5-trifluoro- cyclopropyl CF₃Ph methylpyridin- 2-yl 1367 2-SO₂Me-4- 5-trifluoro- CF₃ CF₃Ph methylpyridin- 2-yl 1368 2-SO₂Me-4- pyrimidin-2-yl H CF₃Ph 1369 2-SO₂Me-4- pyrimidin-2-yl methyl CF₃Ph 1370 2-SO₂Me-4- pyrimidin-2-yl i-propyl CF₃Ph 1371 2-SO₂Me-4- pyrimidin-2-yl cyclopropyl CF₃Ph 1372 2-SO₂Me-4- pyrimidin-2-yl CF₃ CF₃Ph 1373 2-SO₂Me-4- pyrimidin-4-yl H CF₃Ph 1374 2-SO₂Me-4- pyrimidin-4-yl methyl CF₃Ph 1375 2-SO₂Me-4- pyrimidin-4-yl i-propyl CF₃Ph 1376 2-SO₂Me-4- pyrimidin-4-yl cyclopropyl CF₃Ph 1377 2-SO₂Me-4- pyrimidin-4-yl CF₃ CF₃Ph 1378 2-SO₂Me-4- 6-chloro- methyl CF₃Ph pyrimidin-4-yl 1379 2-SO₂Me-4- 6-chloro- i-propyl CF₃Ph pyrimidin-4-yl 1380 2-SO₂Me-4- 6-chloro- cyclopropyl CF₃Ph pyrimidin-4-yl 1381 2-SO₂Me-4- 6-chloro- CF₃ CF₃Ph pyrimidin-4-yl 1382 2-SO₂Me-4- pyridazin-3-yl H CF₃Ph 1383 2-SO₂Me-4- pyridazin-3-yl methyl CF₃Ph 1384 2-SO₂Me-4- pyridazin-3-yl i-propyl CF₃Ph 1385 2-SO₂Me-4- pyridazin-3-yl cyclopropyl CF₃Ph 1386 2-SO₂Me-4- pyridazin-3-yl CF₃ CF₃Ph 1387 2-SO₂Me-4- 6-chloro- methyl CF₃Ph pyridazin-3-yl 1388 2-SO₂Me-4- 6-chloro- i-propyl CF₃Ph pyridazin-3-yl 1389 2-SO₂Me-4- 6-chloro- cyclopropyl CF₃Ph pyridazin-3-yl 1390 2-SO₂Me-4- 6-chloro- CF₃ CF₃Ph pyridazin-3-yl 1391 2-SO₂Me-4- pyrazin-2-yl methyl CF₃Ph 1392 2-SO₂Me-4- pyrazin-2-yl i-propyl CF₃Ph 1393 2-SO₂Me-4- pyrazin-2-yl cyclopropyl CF₃Ph 1394 2-SO₂Me-4- pyrazin-2-yl CF₃ CF₃Ph 1395 2-SO₂Me-4- triazin-2-yl methyl CF₃Ph 1396 2-SO₂Me-4- triazin-2-yl i-propyl CF₃Ph 1397 2-SO₂Me-4- triazin-2-yl cyclopropyl CF₃Ph 1398 2-SO₂Me-4- triazin-2-yl CF₃ CF₃Ph 1399 2-SO₂Me-4- quinolin-2-yl methyl CF₃Ph 1400 2-SO₂Me-4- quinolin-2-yl i-propyl CF₃Ph 1401 2-SO₂Me-4- quinolin-2-yl cyclopropyl CF₃Ph 1402 2-SO₂Me-4- quinolin-2-yl CF₃ CF₃Ph 1403 2-SO₂Me-4- 4,4,6-trimethyl- H CF₃Ph 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1404 2-SO₂Me-4- 4,4,6-trimethyl- methyl CF₃Ph 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1405 2-SO₂Me-4- 4,4,6-trimethyl- i-propyl CF₃Ph 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1406 2-SO₂Me-4- 4,4,6-trimethyl- cyclopropyl CF₃Ph 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1407 2-SO₂Me-4- 4,4,6-trimethyl- CF₃ CF₃Ph 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1408 2-SO₂Me-4- 2-oxazolidinon- H CF₃Ph 3-yl 1409 2-SO₂Me-4- 2-oxazolidinon- methyl CF₃Ph 3-yl 1410 2-SO₂Me-4- 2-oxazolidinon- i-propyl CF₃Ph 3-yl 1411 2-SO₂Me-4- 2-oxazolidinon- cyclopropyl CF₃Ph 3-yl 1412 2-SO₂Me-4- 2-oxazolidinon- CF₃ CF₃Ph 3-yl 1413 2-SO₂Me-4- 2-pyrrolidinon- methyl CF₃Ph 1-yl 1414 2-SO₂Me-4- 2-pyrrolidinon- i-propyl CF₃Ph 1-yl 1415 2-SO₂Me-4- 2-pyrrolidinon- cyclopropyl CF₃Ph 1-yl 1416 2-SO₂Me-4- 2-pyrrolidinon- CF₃ CF₃Ph 1-yl 1417 2-SO₂Me-4- 3-methylisoxazol- methyl CF₃Ph 5-yl 1418 2-SO₂Me-4- 3-methylisoxazol- i-propyl CF₃Ph 5-yl 1419 2-SO₂Me-4- 3-methylisoxazol- cyclopropyl CF₃Ph 5-yl 1420 2-SO₂Me-4- 3-methylisoxazol- CF₃ CF₃Ph 5-yl 1421 2-SO₂Me-4- 2-NO₂-4- H CF₃Ph SO₂MePh 1422 2-SO₂Me-4- 2-NO₂-4- methyl CF₃Ph SO₂MePh 1423 2-SO₂Me-4- 2-NO₂-4- i-propyl CF₃Ph SO₂MePh 1424 2-SO₂Me-4- 2-NO₂-4- cyclopropyl CF₃Ph SO₂MePh 1425 2-SO₂Me-4- 2-NO₂-4- CF₃ CF₃Ph SO₂MePh 1426 2-SO₂Me-4- 2-Cl-4-SO₂MePh H CF₃Ph 1427 2-SO₂Me-4- 2-Cl-4-SO₂MePh methyl CF₃Ph 1428 2-SO₂Me-4- 2-Cl-4-SO₂MePh i-propyl CF₃Ph 1429 2-SO₂Me-4- 2-Cl-4-SO₂MePh cyclopropyl CF₃Ph 1430 2-SO₂Me-4- 2-Cl-4-SO₂MePh CF₃ CF₃Ph 1431 2-SO₂Me-4- 2-NO₂-4-CF₃Ph H CF₃Ph 1432 2-SO₂Me-4- 2-NO₂-4-CF₃Ph methyl CF₃Ph 1433 2-SO₂Me-4- 2-NO₂-4-CF₃Ph i-propyl CF₃Ph 1434 2-SO₂Me-4- 2-NO₂-4-CF₃Ph cyclopropyl CF₃Ph 1435 2-SO₂Me-4- 2-NO₂-4-CF₃Ph CF₃ CF₃Ph 1436 2-SO₂Me-4- 2-NO₂-4-ClPh H CF₃Ph 1437 2-SO₂Me-4- 2-NO₂-4-ClPh methyl CF₃Ph 1438 2-SO₂Me-4- 2-NO₂-4-ClPh i-propyl CF₃Ph 1439 2-SO₂Me-4- 2-NO₂-4-ClPh cyclopropyl CF₃Ph 1440 2-SO₂Me-4- 2-NO₂-4-ClPh CF₃ CF₃Ph 1441 2-SO₂Me-4- 2-Cl-4-NO₂Ph H CF₃Ph 1442 2-SO₂Me-4- 2-Cl-4-NO₂Ph methyl CF₃Ph 1443 2-SO₂Me-4- 2-Cl-4-NO₂Ph i-propyl CF₃Ph 1444 2-SO₂Me-4- 2-Cl-4-NO₂Ph cyclopropyl CF₃Ph 1445 2-SO₂Me-4- 2-Cl-4-NO₂Ph CF₃ CF₃Ph 1446 2-SO₂Me-4- 2,4-(NO₂)₂Ph H CF₃Ph 1447 2-SO₂Me-4- 2,4-(NO₂)₂Ph methyl CF₃Ph 1448 2-SO₂Me-4- 2,4-(NO₂)₂Ph i-propyl CF₃Ph 1449 2-SO₂Me-4- 2,4-(NO₂)₂Ph cyclopropyl CF₃Ph 1450 2-SO₂Me-4- 2,4-(NO₂)₂Ph CF₃ CF₃Ph 1451 2-SO₂Me-4- 4-F-3-NO₂Ph H CF₃Ph 1452 2-SO₂Me-4- 4-F-3-NO₂Ph methyl CF₃Ph 1453 2-SO₂Me-4- 4-F-3-NO₂Ph i-propyl CF₃Ph 1454 2-SO₂Me-4- 4-F-3-NO₂Ph cyclopropyl CF₃Ph 1455 2-SO₂Me-4- 4-F-3-NO₂Ph CF₃ CF₃Ph 1456 2-SO₂Me-4- 3,5-(CF₃)₂Ph H CF₃Ph 1457 2-SO₂Me-4- 3,5-(CF₃)₂Ph methyl CF₃Ph 1458 2-SO₂Me-4- 3,5-(CF₃)₂Ph i-propyl CF₃Ph 1459 2-SO₂Me-4- 3,5-(CF₃)₂Ph cyclopropyl CF₃Ph 1460 2-SO₂Me-4- 3,5-(CF₃)₂Ph CF₃ CF₃Ph 1461 2-SO₂Me-4- 2-SO₂Me-4- H CF₃Ph CF₃Ph 1462 2-SO₂Me-4- 2-SO₂Me-4- methyl CF₃Ph CF₃Ph 1463 2-SO₂Me-4- 2-SO₂Me-4- i-propyl CF₃Ph CF₃Ph 1464 2-SO₂Me-4- 2-SO₂Me-4- cyclopropyl CF₃Ph CF₃Ph 1465 2-SO₂Me-4- 2-SO₂Me-4- CF₃ CF₃Ph CF₃Ph 1466 3-Cl-5- 1,2,4-oxadiazol-5- H CF₃Pyridin-2-yl yl 1467 3-Cl-5- 1,2,4-oxadiazol-5- methyl CF₃Pyridin-2-yl yl 1468 3-Cl-5- 1,2,4-oxadiazol-5- i-propyl CF₃Pyridin-2-yl yl 1469 3-Cl-5- 1,2,4-oxadiazol-5- cyclopropyl CF₃Pyridin-2-yl yl 1470 3-Cl-5- 1,2,4-oxadiazol-5- CF₃ CF₃Pyridin-2-yl yl 1471 3-Cl-5- 3-methyl-1,2,4- H CF₃Pyridin-2-yl oxadiazol-5-yl 1472 3-Cl-5- 3-methyl-1,2,4- methyl CF₃Pyridin-2-yl oxadiazol-5-yl 1473 3-Cl-5- 3-methyl-1,2,4- i-propyl CF₃Pyridin-2-yl oxadiazol-5-yl 1474 3-Cl-5- 3-methyl-1,2,4- cyclopropyl CF₃Pyridin-2-yl oxadiazol-5-yl 1475 3-Cl-5- 3-methyl-1,2,4- CF₃ CF₃Pyridin-2-yl oxadiazol-5-yl 1476 3-Cl-5- 3-trifluoromethyl- H CF₃Pyridin-2-yl 1,2,4-oxadiazol- 5-yl 1477 3-Cl-5- 3-trifluoromethyl- methyl CF₃Pyridin-2-yl 1,2,4-oxadiazol- 5-yl 1478 3-Cl-5- 3-trifluoromethyl- i-propyl CF₃Pyridin-2-yl 1,2,4-oxadiazol- 5-yl 1479 3-Cl-5- 3-trifluoromethyl- cyclopropyl CF₃Pyridin-2-yl 1,2,4-oxadiazol- 5-yl 1480 3-Cl-5- 3-trifluoromethyl- CF₃ CF₃Pyridin-2-yl 1,2,4-oxadiazol- 5-yl 1481 3-Cl-5- 1,2,4-oxadiazol-3- H CF₃Pyridin-2-yl yl 1482 3-Cl-5- 1,2,4-oxadiazol-3- methyl CF₃Pyridin-2-yl yl 1483 3-Cl-5- 1,2,4-oxadiazol-3- i-propyl CF₃Pyridin-2-yl yl 1484 3-Cl-5- 1,2,4-oxadiazol-3- cyclopropyl CF₃Pyridin-2-yl yl 1485 3-Cl-5- 1,2,4-oxadiazol-3- CF₃ CF₃Pyridin-2-yl yl 1486 3-Cl-5- 5-methyl-1,2,4- H CF₃Pyridin-2-yl oxadiazol-3-yl 1487 3-Cl-5- 5-methyl-1,2,4- methyl CF₃Pyridin-2-yl oxadiazol-3-yl 1488 3-Cl-5- 5-methyl-1,2,4- i-propyl CF₃Pyridin-2-yl oxadiazol-3-yl 1489 3-Cl-5- 5-methyl-1,2,4- cyclopropyl CF₃Pyridin-2-yl oxadiazol-3-yl 1490 3-Cl-5- 5-methyl-1,2,4- CF₃ CF₃Pyridin-2-yl oxadiazol-3-yl 1491 3-Cl-5- 5-trifluoromethyl- H CF₃Pyridin-2-yl 1,2,4-oxadiazol- 3-yl 1492 3-Cl-5- 5-trifluoromethyl- methyl CF₃Pyridin-2-yl 1,2,4-oxadiazol- 3-yl 1493 3-Cl-5- 5-trifluoromethyl- i-propyl CF₃Pyridin-2-yl 1,2,4-oxadiazol- 3-yl 1494 3-Cl-5- 5-trifluoromethyl- cyclopropyl CF₃Pyridin-2-yl 1,2,4-oxadiazol- 3-yl 1495 3-Cl-5- 5-trifluoromethyl- CF₃ CF₃Pyridin-2-yl 1,2,4-oxadiazol- 3-yl 1496 3-Cl-5- 5-chloro-1,2,4- H CF₃Pyridin-2-yl oxadiazol-3-yl 1497 3-Cl-5- 5-chloro-1,2,4- methyl CF₃Pyridin-2-yl oxadiazol-3-yl 1498 3-Cl-5- 5-chloro-1,2,4- i-propyl CF₃Pyridin-2-yl oxadiazol-3-yl 1499 3-Cl-5- 5-chloro-1,2,4- cyclopropyl CF₃Pyridin-2-yl oxadiazol-3-yl 1500 3-Cl-5- 5-chloro-1,2,4- CF₃ CF₃Pyridin-2-yl oxadiazol-3-yl 1501 3-Cl-5- 1,3,4-oxadiazol-2- H CF₃Pyridin-2-yl yl 1502 3-Cl-5- 1,3,4-oxadiazol-2- methyl CF₃Pyridin-2-yl yl 1503 3-Cl-5- 1,3,4-oxadiazol-2- i-propyl CF₃Pyridin-2-yl yl 1504 3-Cl-5- 1,3,4-oxadiazol-2- cyclopropyl CF₃Pyridin-2-yl yl 1505 3-Cl-5- 1,3,4-oxadiazol-2- CF₃ CF₃Pyridin-2-yl yl 1506 3-Cl-5- 5-methylsulfonyl- H CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1507 3-Cl-5- 5-methylsulfonyl- methyl CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1508 3-Cl-5- 5-methylsulfonyl- i-propyl CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1509 3-Cl-5- 5-methylsulfonyl- cyclopropyl CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1510 3-Cl-5- 5-methylsulfonyl- CF₃ CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1511 3-Cl-5- 5-methyl-1,3,4- H CF₃Pyridin-2-yl oxadiazol-2-yl 1512 3-Cl-5- 5-methyl-1,3,4- methyl CF₃Pyridin-2-yl oxadiazol-2-yl 1513 3-Cl-5- 5-methyl-1,3,4- i-propyl CF₃Pyridin-2-yl oxadiazol-2-yl 1514 3-Cl-5- 5-methyl-1,3,4- cyclopropyl CF₃Pyridin-2-yl oxadiazol-2-yl 1515 3-Cl-5- 5-methyl-1,3,4- CF₃ CF₃Pyridin-2-yl oxadiazol-2-yl 1516 3-Cl-5- 5-trifluoromethyl- H CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1517 3-Cl-5- 5-trifluoromethyl- methyl CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1518 3-Cl-5- 5-trifluoromethyl- i-propyl CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1519 3-Cl-5- 5-trifluoromethyl- cyclopropyl CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1520 3-Cl-5- 5-trifluoromethyl- CF₃ CF₃Pyridin-2-yl 1,3,4-oxadiazol- 2-yl 1521 3-Cl-5- 1,2,3-triazol-4-yl H CF₃Pyridin-2-yl 1522 3-Cl-5- 1,2,3-triazol-4-yl methyl CF₃Pyridin-2-yl 1523 3-Cl-5- 1,2,3-triazol-4-yl i-propyl CF₃Pyridin-2-yl 1524 3-Cl-5- 1,2,3-triazol-4-yl cyclopropyl CF₃Pyridin-2-yl 1525 3-Cl-5- 1,2,3-triazol-4-yl CF₃ CF₃Pyridin-2-yl 1526 3-Cl-5- 1-methyl-1,2,3- H CF₃Pyridin-2-yl triazol-4-yl 1527 3-Cl-5- 1-methyl-1,2,3- methyl CF₃Pyridin-2-yl triazol-4-yl 1528 3-Cl-5- 1-methyl-1,2,3- i-propyl CF₃Pyridin-2-yl triazol-4-yl 1529 3-Cl-5- 1-methyl-1,2,3- cyclopropyl CF₃Pyridin-2-yl triazol-4-yl 1530 3-Cl-5- 1-methyl-1,2,3- CF₃ CF₃Pyridin-2-yl triazol-4-yl 1531 3-Cl-5- 2-methyl-1,2,3- H CF₃Pyridin-2-yl triazol-4-yl 1532 3-Cl-5- 2-methyl-1,2,3- methyl CF₃Pyridin-2-yl triazol-4-yl 1533 3-Cl-5- 2-methyl-1,2,3- i-propyl CF₃Pyridin-2-yl triazol-4-yl 1534 3-Cl-5- 2-methyl-1,2,3- cyclopropyl CF₃Pyridin-2-yl triazol-4-yl 1535 3-Cl-5- 2-methyl-1,2,3- CF₃ CF₃Pyridin-2-yl triazol-4-yl 1536 3-Cl-5- 1,2,3-triazol-1-yl H CF₃Pyridin-2-yl 1537 3-Cl-5- 1,2,3-triazol-1-yl methyl CF₃Pyridin-2-yl 1538 3-Cl-5- 1,2,3-triazol-1-yl i-propyl CF₃Pyridin-2-yl 1539 3-Cl-5- 1,2,3-triazol-1-yl cyclopropyl CF₃Pyridin-2-yl 1540 3-Cl-5- 1,2,3-triazol-1-yl CF₃ CF₃Pyridin-2-yl 1541 3-Cl-5- 1,2,3-triazol-2-yl H CF₃Pyridin-2-yl 1542 3-Cl-5- 1,2,3-triazol-2-yl methyl CF₃Pyridin-2-yl 1543 3-Cl-5- 1,2,3-triazol-2-yl i-propyl CF₃Pyridin-2-yl 1544 3-Cl-5- 1,2,3-triazol-2-yl cyclopropyl CF₃Pyridin-2-yl 1545 3-Cl-5- 1,2,3-triazol-2-yl CF₃ CF₃Pyridin-2-yl 1546 3-Cl-5- 1,2,4-triazol-1-yl H CF₃Pyridin-2-yl 1547 3-Cl-5- 1,2,4-triazol-1-yl methyl CF₃Pyridin-2-yl 1548 3-Cl-5- 1,2,4-triazol-1-yl i-propyl CF₃Pyridin-2-yl 1549 3-Cl-5- 1,2,4-triazol-1-yl cyclopropyl CF₃Pyridin-2-yl 1550 3-Cl-5- 1,2,4-triazol-1-yl CF₃ CF₃Pyridin-2-yl 1551 3-Cl-5- imidazol-2-yl H CF₃Pyridin-2-yl 1552 3-Cl-5- imidazol-2-yl methyl CF₃Pyridin-2-yl 1553 3-Cl-5- imidazol-2-yl i-propyl CF₃Pyridin-2-yl 1554 3-Cl-5- imidazol-2-yl cyclopropyl CF₃Pyridin-2-yl 1555 3-Cl-5- imidazol-2-yl CF₃ CF₃Pyridin-2-yl 1556 3-Cl-5- imidazol-1-yl H CF₃Pyridin-2-yl 1557 3-Cl-5- imidazol-1-yl methyl CF₃Pyridin-2-yl 1558 3-Cl-5- imidazol-1-yl i-propyl CF₃Pyridin-2-yl 1559 3-Cl-5- imidazol-1-yl cyclopropyl CF₃Pyridin-2-yl 1560 3-Cl-5- imidazol-1-yl CF₃ CF₃Pyridin-2-yl 1561 3-Cl-5- imidazol-4-yl H CF₃Pyridin-2-yl 1562 3-Cl-5- imidazol-4-yl methyl CF₃Pyridin-2-yl 1563 3-Cl-5- imidazol-4-yl i-propyl CF₃Pyridin-2-yl 1564 3-Cl-5- imidazol-4-yl cyclopropyl CF₃Pyridin-2-yl 1565 3-Cl-5- imidazol-4-yl CF₃ CF₃Pyridin-2-yl 1566 3-Cl-5- thiazol-2-yl H CF₃Pyridin-2-yl 1567 3-Cl-5- thiazol-2-yl methyl CF₃Pyridin-2-yl 1568 3-Cl-5- thiazol-2-yl i-propyl CF₃Pyridin-2-yl 1569 3-Cl-5- thiazol-2-yl cyclopropyl CF₃Pyridin-2-yl 1570 3-Cl-5- thiazol-2-yl CF₃ CF₃Pyridin-2-yl 1571 3-Cl-5- 4-methylthiazol- H CF₃Pyridin-2-yl 2-yl 1572 3-Cl-5- 4-methylthiazol- methyl CF₃Pyridin-2-yl 2-yl 1573 3-Cl-5- 4-methylthiazol- i-propyl CF₃Pyridin-2-yl 2-yl 1574 3-Cl-5- 4-methylthiazol- cyclopropyl CF₃Pyridin-2-yl 2-yl 1575 3-Cl-5- 4-methylthiazol- CF₃ CF₃Pyridin-2-yl 2-yl 1576 3-Cl-5- oxazol-2-yl H CF₃Pyridin-2-yl 1577 3-Cl-5- oxazol-2-yl methyl CF₃Pyridin-2-yl 1578 3-Cl-5- oxazol-2-yl i-propyl CF₃Pyridin-2-yl 1579 3-Cl-5- oxazol-2-yl cyclopropyl CF₃Pyridin-2-yl 1580 3-Cl-5- oxazol-2-yl CF₃ CF₃Pyridin-2-yl 1581 3-Cl-5- 4,5-dimethyl- H CF₃Pyridin-2-yl oxazol-2-yl 1582 3-Cl-5- 4,5-dimethyl- methyl CF₃Pyridin-2-yl oxazol-2-yl 1583 3-Cl-5- 4,5-dimethyl- i-propyl CF₃Pyridin-2-yl oxazol-2-yl 1584 3-Cl-5- 4,5-dimethyl- cyclopropyl CF₃Pyridin-2-yl oxazol-2-yl 1585 3-Cl-5- 4,5-dimethyl- CF₃ CF₃Pyridin-2-yl oxazol-2-yl 1586 3-Cl-5- 2-oxazolin-2-yl H CF₃Pyridin-2-yl 1587 3-Cl-5- 2-oxazolin-2-yl methyl CF₃Pyridin-2-yl 1588 3-Cl-5- 2-oxazolin-2-yl i-propyl CF₃Pyridin-2-yl 1589 3-Cl-5- 2-oxazolin-2-yl cyclopropyl CF₃Pyridin-2-yl 1590 3-Cl-5- 2-oxazolin-2-yl CF₃ CF₃Pyridin-2-yl 1591 3-Cl-5- 4,4-dimethyl-2- H CF₃Pyridin-2-yl oxazolin-2-yl 1592 3-Cl-5- 4,4-dimethyl-2- methyl CF₃Pyridin-2-yl oxazolin-2-yl 1593 3-Cl-5- 4,4-dimethyl-2- i-propyl CF₃Pyridin-2-yl oxazolin-2-yl 1594 3-Cl-5- 4,4-dimethyl-2- cyclopropyl CF₃Pyridin-2-yl oxazolin-2-yl 1595 3-Cl-5- 4,4-dimethyl-2- CF₃ CF₃Pyridin-2-yl oxazolin-2-yl 1596 3-Cl-5- 1,2,4-thiadiazol- H CF₃Pyridin-2-yl 5-yl 1597 3-Cl-5- 1,2,4-thiadiazol- methyl CF₃Pyridin-2-yl 5-yl 1598 3-Cl-5- 1,2,4-thiadiazol- i-propyl CF₃Pyridin-2-yl 5-yl 1599 3-Cl-5- 1,2,4-thiadiazol- cyclopropyl CF₃Pyridin-2-yl 5-yl 1600 3-Cl-5- 1,2,4-thiadiazol- CF₃ CF₃Pyridin-2-yl 5-yl 1601 3-Cl-5- 3-methyl-1,2,4- H CF₃Pyridin-2-yl thiadiazol-5-yl 1602 3-Cl-5- 3-methyl-1,2,4- methyl CF₃Pyridin-2-yl thiadiazol-5-yl 1603 3-Cl-5- 3-methyl-1,2,4- i-propyl CF₃Pyridin-2-yl thiadiazol-5-yl 1604 3-Cl-5- 3-methyl-1,2,4- cyclopropyl CF₃Pyridin-2-yl thiadiazol-5-yl 1605 3-Cl-5- 3-methyl-1,2,4- CF₃ CF₃Pyridin-2-yl thiadiazol-5-yl 1606 3-Cl-5- 3-trifluoromethyl- H CF₃Pyridin-2-yl 1,2,4-thiadiazol- 5-yl 1607 3-Cl-5- 3-trifluoromethyl- methyl CF₃Pyridin-2-yl 1,2,4-thiadiazol- 5-yl 1608 3-Cl-5- 3-trifluoromethyl- i-propyl CF₃Pyridin-2-yl 1,2,4-thiadiazol- 5-yl 1609 3-Cl-5- 3-trifluoromethyl- cyclopropyl CF₃Pyridin-2-yl 1,2,4-thiadiazol- 5-yl 1610 3-Cl-5- 3-trifluoromethyl- CF₃ CF₃Pyridin-2-yl 1,2,4-thiadiazol- 5-yl 1611 3-Cl-5- 1,2,4-thiadiazol- H CF₃Pyridin-2-yl 3-yl 1612 3-Cl-5- 1,2,4-thiadiazol- methyl CF₃Pyridin-2-yl 3-yl 1613 3-Cl-5- 1,2,4-thiadiazol- i-propyl CF₃Pyridin-2-yl 3-yl 1614 3-Cl-5- 1,2,4-thiadiazol- cyclopropyl CF₃Pyridin-2-yl 3-yl 1615 3-Cl-5- 1,2,4-thiadiazol- CF₃ CF₃Pyridin-2-yl 3-yl 1616 3-Cl-5- 5-methyl-1,2,4- H CF₃Pyridin-2-yl thiadiazol-3-yl 1617 3-Cl-5- 5-methyl-1,2,4- methyl CF₃Pyridin-2-yl thiadiazol-3-yl 1618 3-Cl-5- 5-methyl-1,2,4- i-propyl CF₃Pyridin-2-yl thiadiazol-3-yl 1619 3-Cl-5- 5-methyl-1,2,4- cyclopropyl CF₃Pyridin-2-yl thiadiazol-3-yl 1620 3-Cl-5- 5-methyl-1,2,4- CF₃ CF₃Pyridin-2-yl thiadiazol-3-yl 1621 3-Cl-5- 5-trifluoromethyl- H CF₃Pyridin-2-yl 1,2,4-thiadiazol- 3-yl 1622 3-Cl-5- 5-trifluoromethyl- methyl CF₃Pyridin-2-yl 1,2,4-thiadiazol- 3-yl 1623 3-Cl-5- 5-trifluoromethyl- i-propyl CF₃Pyridin-2-yl 1,2,4-thiadiazol- 3-yl 1624 3-Cl-5- 5-trifluoromethyl- cyclopropyl CF₃Pyridin-2-yl 1,2,4-thiadiazol- 3-yl 1625 3-Cl-5- 5-trifluoromethyl- CF₃ CF₃Pyridin-2-yl 1,2,4-thiadiazol- 3-yl 1626 3-Cl-5- 1,3,4-thiadiazol- H CF₃Pyridin-2-yl 2-yl 1627 3-Cl-5- 1,3,4-thiadiazol- methyl CF₃Pyridin-2-yl 2-yl 1628 3-Cl-5- 1,3,4-thiadiazol- i-propyl CF₃Pyridin-2-yl 2-yl 1629 3-Cl-5- 1,3,4-thiadiazol- cyclopropyl CF₃Pyridin-2-yl 2-yl 1630 3-Cl-5- 1,3,4-thiadiazol- CF₃ CF₃Pyridin-2-yl 2-yl 1631 3-Cl-5- 5-methylsulfonyl- H CF₃Pyridin-2-yl 1,3,4-thiadiazol- 2-yl 1632 3-Cl-5- 5-methylsulfonyl- methyl CF₃Pyridin-2-yl 1,3,4-thiadiazol- 2-yl 1633 3-Cl-5- 5-methylsulfonyl- i-propyl CF₃Pyridin-2-yl 1,3,4-thiadiazol- 2-yl 1634 3-Cl-5- 5-methylsulfonyl- cyclopropyl CF₃Pyridin-2-yl 1,3,4-thiadiazol- 2-yl 1635 3-Cl-5- 5-methylsulfonyl- CF₃ CF₃Pyridin-2-yl 1,3,4-thiadiazol- 2-yl 1636 3-Cl-5- 5-methyl-1,3,4- H CF₃Pyridin-2-yl thiadiazol-2-yl 1637 3-Cl-5- 5-methyl-1,3,4- methyl CF₃Pyridin-2-yl thiadiazol-2-yl 1638 3-Cl-5- 5-methyl-1,3,4- i-propyl CF₃Pyridin-2-yl thiadiazol-2-yl 1639 3-Cl-5- 5-methyl-1,3,4- cyclopropyl CF₃Pyridin-2-yl thiadiazol-2-yl 1640 3-Cl-5- 5-methyl-1,3,4- CF₃ CF₃Pyridin-2-yl thiadiazol-2-yl 1641 3-Cl-5- benzoxazol-2-yl H CF₃Pyridin-2-yl 1642 3-Cl-5- benzoxazol-2-yl methyl CF₃Pyridin-2-yl 1643 3-Cl-5- benzoxazol-2-yl i-propyl CF₃Pyridin-2-yl 1644 3-Cl-5- benzoxazol-2-yl cyclopropyl CF₃Pyridin-2-yl 1645 3-Cl-5- benzoxazol-2-yl CF₃ CF₃Pyridin-2-yl 1646 3-Cl-5- 6-methyl- H CF₃Pyridin-2-yl benzoxazol-2-yl 1647 3-Cl-5- 6-methyl- methyl CF₃Pyridin-2-yl benzoxazol-2-yl 1648 3-Cl-5- 6-methyl- i-propyl CF₃Pyridin-2-yl benzoxazol-2-yl 1649 3-Cl-5- 6-methyl- cyclopropyl CF₃Pyridin-2-yl benzoxazol-2-yl 1650 3-Cl-5- 6-methyl- CF₃ CF₃Pyridin-2-yl benzoxazol-2-yl 1651 3-Cl-5- benzothiazol-2-yl H CF₃Pyridin-2-yl 1652 3-Cl-5- benzothiazol-2-yl methyl CF₃Pyridin-2-yl 1653 3-Cl-5- benzothiazol-2-yl i-propyl CF₃Pyridin-2-yl 1654 3-Cl-5- benzothiazol-2-yl cyclopropyl CF₃Pyridin-2-yl 1655 3-Cl-5- benzothiazol-2-yl CF₃ CF₃Pyridin-2-yl 1656 3-Cl-5- pyrazol-1-yl H CF₃Pyridin-2-yl 1657 3-Cl-5- pyrazol-1-yl methyl CF₃Pyridin-2-yl 1658 3-Cl-5- pyrazol-1-yl i-propyl CF₃Pyridin-2-yl 1659 3-Cl-5- pyrazol-1-yl cyclopropyl CF₃Pyridin-2-yl 1660 3-Cl-5- pyrazol-1-yl CF₃ CF₃Pyridin-2-yl 1661 3-Cl-5- pyrazol-3-yl H CF₃Pyridin-2-yl 1662 3-Cl-5- pyrazol-3-yl methyl CF₃Pyridin-2-yl 1663 3-Cl-5- pyrazol-3-yl i-propyl CF₃Pyridin-2-yl 1664 3-Cl-5- pyrazol-3-yl cyclopropyl CF₃Pyridin-2-yl 1665 3-Cl-5- pyrazol-3-yl CF₃ CF₃Pyridin-2-yl 1666 3-Cl-5- 1-methylpyrazol- H CF₃Pyridin-2-yl 3-yl 1667 3-Cl-5- 1-methylpyrazol- methyl CF₃Pyridin-2-yl 3-yl 1668 3-Cl-5- 1-methylpyrazol- i-propyl CF₃Pyridin-2-yl 3-yl 1669 3-Cl-5- 1-methylpyrazol- cyclopropyl CF₃Pyridin-2-yl 3-yl 1670 3-Cl-5- 1-methylpyrazol- CF₃ CF₃Pyridin-2-yl 3-yl 1671 3-Cl-5- tetrazol-1-yl H CF₃Pyridin-2-yl 1672 3-Cl-5- tetrazol-1-yl methyl CF₃Pyridin-2-yl 1673 3-Cl-5- tetrazol-1-yl i-propyl CF₃Pyridin-2-yl 1674 3-Cl-5- tetrazol-1-yl cyclopropyl CF₃Pyridin-2-yl 1675 3-Cl-5- tetrazol-1-yl CF₃ CF₃Pyridin-2-yl 1676 3-Cl-5- 5-methyltetrazol- H CF₃Pyridin-2-yl 1-yl 1677 3-Cl-5- 5-methyltetrazol- methyl CF₃Pyridin-2-yl 1-yl 1678 3-Cl-5- 5-methyltetrazol- i-propyl CF₃Pyridin-2-yl 1-yl 1679 3-Cl-5- 5-methyltetrazol- cyclopropyl CF₃Pyridin-2-yl 1-yl 1680 3-Cl-5- 5-methyltetrazol- CF₃ CF₃Pyridin-2-yl 1-yl 1681 3-Cl-5- tetrazol-2-yl H CF₃Pyridin-2-yl 1682 3-Cl-5- tetrazol-2-yl methyl CF₃Pyridin-2-yl 1683 3-Cl-5- tetrazol-2-yl i-propyl CF₃Pyridin-2-yl 1684 3-Cl-5- tetrazol-2-yl cyclopropyl CF₃Pyridin-2-yl 1685 3-Cl-5- tetrazol-2-yl CF₃ CF₃Pyridin-2-yl 1686 3-Cl-5- 5-methyltetrazol- H CF₃Pyridin-2-yl 2-yl 1687 3-Cl-5- 5-methyltetrazol- methyl CF₃Pyridin-2-yl 2-yl 1688 3-Cl-5- 5-methyltetrazol- i-propyl CF₃Pyridin-2-yl 2-yl 1689 3-Cl-5- 5-methyltetrazol- cyclopropyl CF₃Pyridin-2-yl 2-yl 1690 3-Cl-5- 5-methyltetrazol- CF₃ CF₃Pyridin-2-yl 2-yl 1691 3-Cl-5- 1-methyltetrazol- H CF₃Pyridin-2-yl 5-yl 1692 3-Cl-5- 1-methyltetrazol- methyl CF₃Pyridin-2-yl 5-yl 1693 3-Cl-5- 1-methyltetrazol- i-propyl CF₃Pyridin-2-yl 5-yl 1694 3-Cl-5- 1-methyltetrazol- cyclopropyl CF₃Pyridin-2-yl 5-yl 1695 3-Cl-5- 1-methyltetrazol- CF₃ CF₃Pyridin-2-yl 5-yl 1696 3-Cl-5- 2-methyltetrazol- H CF₃Pyridin-2-yl 5-yl 1697 3-Cl-5- 2-methyltetrazol- methyl CF₃Pyridin-2-yl 5-yl 1698 3-Cl-5- 2-methyltetrazol- i-propyl CF₃Pyridin-2-yl 5-yl 1699 3-Cl-5- 2-methyltetrazol- cyclopropyl CF₃Pyridin-2-yl 5-yl 1700 3-Cl-5- 2-methyltetrazol- CF₃ CF₃Pyridin-2-yl 5-yl 1701 3-Cl-5- pyridin-2-yl H CF₃Pyridin-2-yl 1702 3-Cl-5- pyridin-2-yl methyl CF₃Pyridin-2-yl 1703 3-Cl-5- pyridin-2-yl i-propyl CF₃Pyridin-2-yl 1704 3-Cl-5- pyridin-2-yl cyclopropyl CF₃Pyridin-2-yl 1705 3-Cl-5- pyridin-2-yl CF₃ CF₃Pyridin-2-yl 1706 3-Cl-5- pyridin-4-yl H CF₃Pyridin-2-yl 1707 3-Cl-5- pyridin-4-yl methyl CF₃Pyridin-2-yl 1708 3-Cl-5- pyridin-4-yl i-propyl CF₃Pyridin-2-yl 1709 3-Cl-5- pyridin-4-yl cyclopropyl CF₃Pyridin-2-yl 1710 3-Cl-5- pyridin-4-yl CF₃ CF₃Pyridin-2-yl 1711 3-Cl-5- pyridin-3-yl H CF₃Pyridin-2-yl 1712 3-Cl-5- pyridin-3-yl methyl CF₃Pyridin-2-yl 1713 3-Cl-5- pyridin-3-yl i-propyl CF₃Pyridin-2-yl 1714 3-Cl-5- pyridin-3-yl cyclopropyl CF₃Pyridin-2-yl 1715 3-Cl-5- pyridin-3-yl CF₃ CF₃Pyridin-2-yl 1716 3-Cl-5- 3-nitropyridin- H CF₃Pyridin-2-yl 4-yl 1717 3-Cl-5- 3-nitropyridin- methyl CF₃Pyridin-2-yl 4-yl 1718 3-Cl-5- 3-nitropyridin- i-propyl CF₃Pyridin-2-yl 4-yl 1719 3-Cl-5- 3-nitropyridin- cyclopropyl CF₃Pyridin-2-yl 4-yl 1720 3-Cl-5- 3-nitropyridin- CF₃ CF₃Pyridin-2-yl 4-yl 1721 3-Cl-5- 5-cyanopyridin- H CF₃Pyridin-2-yl 2-yl 1722 3-Cl-5- 5-cyanopyridin- methyl CF₃Pyridin-2-yl 2-yl 1723 3-Cl-5- 5-cyanopyridin- i-propyl CF₃Pyridin-2-yl 2-yl 1724 3-Cl-5- 5-cyanopyridin- cyclopropyl CF₃Pyridin-2-yl 2-yl 1725 3-Cl-5- 5-cyanopyridin- CF₃ CF₃Pyridin-2-yl 2-yl 1726 3-Cl-5- 5-trifluoro- H CF₃Pyridin-2-yl methylpyridin- 2-yl 1727 3-Cl-5- 5-trifluoro- methyl CF₃Pyridin-2-yl methylpyridin- 2-yl 1728 3-Cl-5- 5-trifluoro- i-propyl CF₃Pyridin-2-yl methylpyridin- 2-yl 1729 3-Cl-5- 5-trifluoro- cyclopropyl CF₃Pyridin-2-yl methylpyridin- 2-yl 1730 3-Cl-5- 5-trifluoro- CF₃ CF₃Pyridin-2-yl methylpyridin- 2-yl 1731 3-Cl-5- pyrimidin-2-yl H CF₃Pyridin-2-yl 1732 3-Cl-5- pyrimidin-2-yl methyl CF₃Pyridin-2-yl 1733 3-Cl-5- pyrimidin-2-yl i-propyl CF₃Pyridin-2-yl 1734 3-Cl-5- pyrimidin-2-yl cyclopropyl CF₃Pyridin-2-yl 1735 3-Cl-5- pyrimidin-2-yl CF₃ CF₃Pyridin-2-yl 1736 3-Cl-5- pyrimidin-4-yl H CF₃Pyridin-2-yl 1737 3-Cl-5- pyrimidin-4-yl methyl CF₃Pyridin-2-yl 1738 3-Cl-5- pyrimidin-4-yl i-propyl CF₃Pyridin-2-yl 1739 3-Cl-5- pyrimidin-4-yl cyclopropyl CF₃Pyridin-2-yl 1740 3-Cl-5- pyrimidin-4-yl CF₃ CF₃Pyridin-2-yl 1741 3-Cl-5- 6-chloro- methyl CF₃Pyridin-2-yl pyrimidin-4-yl 1742 3-Cl-5- 6-chloro- i-propyl CF₃Pyridin-2-yl pyrimidin-4-yl 1743 3-Cl-5- 6-chloro- cyclopropyl CF₃Pyridin-2-yl pyrimidin-4-yl 1744 3-Cl-5- 6-chloro- CF₃ CF₃Pyridin-2-yl pyrimidin-4-yl 1745 3-Cl-5- pyridazin-3-yl H CF₃Pyridin-2-yl 1746 3-Cl-5- pyridazin-3-yl methyl CF₃Pyridin-2-yl 1747 3-Cl-5- pyridazin-3-yl i-propyl CF₃Pyridin-2-yl 1748 3-Cl-5- pyridazin-3-yl cyclopropyl CF₃Pyridin-2-yl 1749 3-Cl-5- pyridazin-3-yl CF₃ CF₃Pyridin-2-yl 1750 3-Cl-5- 6-chloro- methyl CF₃Pyridin-2-yl pyridazin-3-yl 1751 3-Cl-5- 6-chloro- i-propyl CF₃Pyridin-2-yl pyridazin-3-yl 1752 3-Cl-5- 6-chloro- cyclopropyl CF₃Pyridin-2-yl pyridazin-3-yl 1753 3-Cl-5- 6-chloro- CF₃ CF₃Pyridin-2-yl pyridazin-3-yl 1754 3-Cl-5- pyrazin-2-yl methyl CF₃Pyridin-2-yl 1755 3-Cl-5- pyrazin-2-yl i-propyl CF₃Pyridin-2-yl 1756 3-Cl-5- pyrazin-2-yl cyclopropyl CF₃Pyridin-2-yl 1757 3-Cl-5- pyrazin-2-yl CF₃ CF₃Pyridin-2-yl 1758 3-Cl-5- triazin-2-yl methyl CF₃Pyridin-2-yl 1759 3-Cl-5- triazin-2-yl i-propyl CF₃Pyridin-2-yl 1760 3-Cl-5- triazin-2-yl cyclopropyl CF₃Pyridin-2-yl 1761 3-Cl-5- triazin-2-yl CF₃ CF₃Pyridin-2-yl 1762 3-Cl-5- quinolin-2-yl methyl CF₃Pyridin-2-yl 1763 3-Cl-5- quinolin-2-yl i-propyl CF₃Pyridin-2-yl 1764 3-Cl-5- quinolin-2-yl cyclopropyl CF₃Pyridin-2-yl 1765 3-Cl-5- quinolin-2-yl CF₃ CF₃Pyridin-2-yl 1766 3-Cl-5- 4,4,6-trimethyl- H CF₃Pyridin-2-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1767 3-Cl-5- 4,4,6-trimethyl- methyl CF₃Pyridin-2-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1768 3-Cl-5- 4,4,6-trimethyl- i-propyl CF₃Pyridin-2-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1769 3-Cl-5- 4,4,6-trimethyl- cyclopropyl CF₃Pyridin-2-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1770 3-Cl-5- 4,4,6-trimethyl- CF₃ CF₃Pyridin-2-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 1771 3-Cl-5- 2-oxazolidinon- H CF₃Pyridin-2-yl 3-yl 1772 3-Cl-5- 2-oxazolidinon- methyl CF₃Pyridin-2-yl 3-yl 1773 3-Cl-5- 2-oxazolidinon- i-propyl CF₃Pyridin-2-yl 3-yl 1774 3-Cl-5- 2-oxazolidinon- cyclopropyl CF₃Pyridin-2-yl 3-yl 1775 3-Cl-5- 2-oxazolidinon- CF₃ CF₃Pyridin-2-yl 3-yl 1776 3-Cl-5- 2-pyrrolidinon- methyl CF₃Pyridin-2-yl 1-yl 1777 3-Cl-5- 2-pyrrolidinon- i-propyl CF₃Pyridin-2-yl 1-yl 1778 3-Cl-5- 2-pyrrolidinon- cyclopropyl CF₃Pyridin-2-yl 1-yl 1779 3-Cl-5- 2-pyrrolidinon- CF₃ CF₃Pyridin-2-yl 1-yl 1780 3-Cl-5- 3-methylisoxazol- methyl CF₃Pyridin-2-yl 5-yl 1781 3-Cl-5- 3-methylisoxazol- i-propyl CF₃Pyridin-2-yl 5-yl 1782 3-Cl-5- 3-methylisoxazol- cyclopropyl CF₃Pyridin-2-yl 5-yl 1783 3-Cl-5- 3-methylisoxazol- CF₃ CF₃Pyridin-2-yl 5-yl 1784 3-Cl-5- 2-NO₂-4- H CF₃Pyridin-2-yl SO₂MePh 1785 3-Cl-5- 2-NO₂-4- methyl CF₃Pyridin-2-yl SO₂MePh 1786 3-Cl-5- 2-NO₂-4- i-propyl CF₃Pyridin-2-yl SO₂MePh 1787 3-Cl-5- 2-NO₂-4- cyclopropyl CF₃Pyridin-2-yl SO₂MePh 1788 3-Cl-5- 2-NO₂-4- CF₃ CF₃Pyridin-2-yl SO₂MePh 1789 3-Cl-5- 2-Cl-4-SO₂MePh H CF₃Pyridin-2-yl 1790 3-Cl-5- 2-Cl-4-SO₂MePh methyl CF₃Pyridin-2-yl 1791 3-Cl-5- 2-Cl-4-SO₂MePh i-propyl CF₃Pyridin-2-yl 1792 3-Cl-5- 2-Cl-4-SO₂MePh cyclopropyl CF₃Pyridin-2-yl 1793 3-Cl-5- 2-Cl-4-SO₂MePh CF₃ CF₃Pyridin-2-yl 1794 3-Cl-5- 2-NO₂-4-CF₃Ph H CF₃Pyridin-2-yl 1795 3-Cl-5- 2-NO₂-4-CF₃Ph methyl CF₃Pyridin-2-yl 1796 3-Cl-5- 2-NO₂-4-CF₃Ph i-propyl CF₃Pyridin-2-yl 1797 3-Cl-5- 2-NO₂-4-CF₃Ph cyclopropyl CF₃Pyridin-2-yl 1798 3-Cl-5- 2-NO₂-4-CF₃Ph CF₃ CF₃Pyridin-2-yl 1799 3-Cl-5- 2-NO₂-4-ClPh H CF₃Pyridin-2-yl 1800 3-Cl-5- 2-NO₂-4-ClPh methyl CF₃Pyridin-2-yl 1801 3-Cl-5- 2-NO₂-4-ClPh i-propyl CF₃Pyridin-2-yl 1802 3-Cl-5- 2-NO₂-4-ClPh cyclopropyl CF₃Pyridin-2-yl 1803 3-Cl-5- 2-NO₂-4-ClPh CF₃ CF₃Pyridin-2-yl 1804 3-Cl-5- 2-Cl-4-NO₂Ph H CF₃Pyridin-2-yl 1805 3-Cl-5- 2-Cl-4-NO₂Ph methyl CF₃Pyridin-2-yl 1806 3-Cl-5- 2-Cl-4-NO₂Ph i-propyl CF₃Pyridin-2-yl 1807 3-Cl-5- 2-Cl-4-NO₂Ph cyclopropyl CF₃Pyridin-2-yl 1808 3-Cl-5- 2-Cl-4-NO₂Ph CF₃ CF₃Pyridin-2-yl 1809 3-Cl-5- 2,4-(NO₂)₂Ph H CF₃Pyridin-2-yl 1810 3-Cl-5- 2,4-(NO₂)₂Ph methyl CF₃Pyridin-2-yl 1811 3-Cl-5- 2,4-(NO₂)₂Ph i-propyl CF₃Pyridin-2-yl 1812 3-Cl-5- 2,4-(NO₂)₂Ph cyclopropyl CF₃Pyridin-2-yl 1813 3-Cl-5- 2,4-(NO₂)₂Ph CF₃ CF₃Pyridin-2-yl 1814 3-Cl-5- 4-F-3-NO₂Ph H CF₃Pyridin-2-yl 1815 3-Cl-5- 4-F-3-NO₂Ph methyl CF₃Pyridin-2-yl 1816 3-Cl-5- 4-F-3-NO₂Ph i-propyl CF₃Pyridin-2-yl 1817 3-Cl-5- 4-F-3-NO₂Ph cyclopropyl CF₃Pyridin-2-yl 1818 3-Cl-5- 4-F-3-NO₂Ph CF₃ CF₃Pyridin-2-yl 1819 3-Cl-5- 3,5-(CF₃)₂Ph H CF₃Pyridin-2-yl 1820 3-Cl-5- 3,5-(CF₃)₂Ph methyl CF₃Pyridin-2-yl 1821 3-Cl-5- 3,5-(CF₃)₂Ph i-propyl CF₃Pyridin-2-yl 1822 3-Cl-5- 3,5-(CF₃)₂Ph cyclopropyl CF₃Pyridin-2-yl 1823 3-Cl-5- 3,5-(CF₃)₂Ph CF₃ CF₃Pyridin-2-yl 1824 3-Cl-5- 2-SO₂Me-4- H CF₃Pyridin-2-yl CF₃Ph 1825 3-Cl-5- 2-SO₂Me-4- methyl CF₃Pyridin-2-yl CF₃Ph 1826 3-Cl-5- 2-SO₂Me-4- i-propyl CF₃Pyridin-2-yl CF₃Ph 1827 3-Cl-5- 2-SO₂Me-4- cyclopropyl CF₃Pyridin-2-yl CF₃Ph 1828 3-Cl-5- 2-SO₂Me-4- CF₃ CF₃Pyridin-2-yl CF₃Ph 1829 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-5- H 5-yl yl 1830 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-5- methyl 5-yl yl 1331 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-5- i-propyl 5-yl yl 1832 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-5- cyclopropyl 5-yl yl 1833 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-5- CF₃ 5-yl yl 1834 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- H 5-yl oxadiazol-5-yl 1835 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- methyl 5-yl oxadiazol-5-yl 1836 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- i-propyl 5-yl oxadiazol-5-yl 1837 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- cyclopropyl 5-yl oxadiazol-5-yl 1838 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- CF₃ 5-yl oxadiazol-5-yl 1839 2,4-(Me)₂Thiazol- 3-trifluoromethyl- H 5-yl 1,2,4-oxadiazol- 5-yl 1840 2,4-(Me)₂Thiazol- 3-trifluoromethyl- methyl 5-yl 1,2,4-oxadiazol- 5-yl 1841 2,4-(Me)₂Thiazol- 3-trifluoromethyl- i-propyl 5-yl 1,2,4-oxadiazol- 5-yl 1842 2,4-(Me)₂Thiazol- 3-trifluoromethyl- cyclopropyl 5-yl 1,2,4-oxadiazol- 5-yl 1843 2,4-(Me)₂Thiazol- 3-trifluoromethyl- CF₃ 5-yl 1,2,4-oxadiazol- 5-yl 1844 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-3- H 5-yl yl 1845 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-3- methyl 5-yl yl 1846 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-3- i-propyl 5-yl yl 1847 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-3- cyclopropyl 5-yl yl 1848 2,4-(Me)₂Thiazol- 1,2,4-oxadiazol-3- CF₃ 5-yl yl 1849 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- H 5-yl oxadiazol-3-yl 1850 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- methyl 5-yl oxadiazol-3-yl 1851 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- i-propyl 5-yl oxadiazol-3-yl 1852 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- cyclopropyl 5-yl oxadiazol-3-yl 1853 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- CF₃ 5-yl oxadiazol-3-yl 1854 2,4-(Me)₂Thiazol- 5-trifluoromethyl- H 5-yl 1,2,4-oxadiazol- 3-yl 1855 2,4-(Me)₂Thiazol- 5-trifluoromethyl- methyl 5-yl 1,2,4-oxadiazol- 3-yl 1856 2,4-(Me)₂Thiazol- 5-trifluoromethyl- i-propyl 5-yl 1,2,4-oxadiazol- 3-yl 1857 2,4-(Me)₂Thiazol- 5-trifluoromethyl- cyclopropyl 5-yl 1,2,4-oxadiazol- 3-yl 1858 2,4-(Me)₂Thiazol- 5-trifluoromethyl- CF₃ 5-yl 1,2,4-oxadiazol- 3-yl 1859 2,4-(Me)₂Thiazol- 5-chloro-1,2,4- H 5-yl oxadiazol-3-yl 1860 2,4-(Me)₂Thiazol- 5-chloro-1,2,4- methyl 5-yl oxadiazol-3-yl 1861 2,4-(Me)₂Thiazol- 5-chloro-1,2,4- i-propyl 5-yl oxadiazol-3-yl 1862 2,4-(Me)₂Thiazol- 5-chloro-1,2,4- cyclopropyl 5-yl oxadiazol-3-yl 1863 2,4-(Me)₂Thiazol- 5-chloro-1,2,4- CF₃ 5-yl oxadiazol-3-yl 1864 2,4-(Me)₂Thiazol- 1,3,4-oxadiazol- H 5-yl 2-yl 1865 2,4-(Me)₂Thiazol- 1,3,4-oxadiazol- methyl 5-yl 2-yl 1866 2,4-(Me)₂Thiazol- 1,3,4-oxadiazol- i-propyl 5-yl 2-yl 1867 2,4-(Me)₂Thiazol- 1,3,4-oxadiazol- cyclopropyl 5-yl 2-yl 1868 2,4-(Me)₂Thiazol- 1,3,4-oxadiazol- CF₃ 5-yl 2-yl 1869 2,4-(Me)₂Thiazol- 5-methylsulfonyl- H 5-yl 1,3,4-oxadiazol- 2-yl 1870 2,4-(Me)₂Thiazol- 5-methylsulfonyl- methyl 5-yl 1,3,4-oxadiazol- 2-yl 1871 2,4-(Me)₂Thiazol- 5-methylsulfonyl- i-propyl 5-yl 1,3,4-oxadiazol- 2-yl 1872 2,4-(Me)₂Thiazol- 5-methylsulfonyl- cyclopropyl 5-yl 1,3,4-oxadiazol- 2-yl 1873 2,4-(Me)₂Thiazol- 5-methylsulfonyl- CF₃ 5-yl 1,3,4-oxadiazol- 2-yl 1874 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- H 5-yl oxadiazol-2-yl 1875 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- methyl 5-yl oxadiazol-2-yl 1876 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- i-propyl 5-yl oxadiazol-2-yl 1877 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- cyclopropyl 5-yl oxadiazol-2-yl 1878 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- CF₃ 5-yl oxadiazol-2-yl 1879 2,4-(Me)₂Thiazol- 5-trifluoromethyl- H 5-yl 1,3,4-oxadiazol- 2-yl 1880 2,4-(Me)₂Thiazol- 5-trifluoromethyl- methyl 5-yl 1,3,4-oxadiazol- 2-yl 1881 2,4-(Me)₂Thiazol- 5-trifluoromethyl- i-propyl 5-yl 1,3,4-oxadiazol- 2-yl 1882 2,4-(Me)₂Thiazol- 5-trifluoromethyl- cyclopropyl 5-yl 1,3,4-oxadiazol- 2-yl 1883 2,4-(Me)₂Thiazol- 5-trifluoromethyl- CF₃ 5-yl 1,3,4-oxadiazol- 2-yl 1884 2,4-(Me)₂Thiazol- 1,2,3-triazol-4-yl H 5-yl 1885 2,4-(Me)₂Thiazol- 1,2,3-triazol-4-yl methyl 5-yl 1886 2,4-(Me)₂Thiazol- 1,2,3-triazol-4-yl i-propyl 5-yl 1887 2,4-(Me)₂Thiazol- 1,2,3-triazol-4-yl cyclopropyl 5-yl 1888 2,4-(Me)₂Thiazol- 1,2,3-triazol-4-yl CF₃ 5-yl 1889 2,4-(Me)₂Thiazol- 1-methyl-1,2,3- H 5-yl triazol-4-yl 1890 2,4-(Me)₂Thiazol- 1-methyl-1,2,3- methyl 5-yl triazol-4-yl 1891 2,4-(Me)₂Thiazol- 1-methyl-1,2,3- i-propyl 5-yl triazol-4-yl 1892 2,4-(Me)₂Thiazol- 1-methyl-1,2,3- cyclopropyl 5-yl triazol-4-yl 1893 2,4-(Me)₂Thiazol- 1-methyl-1,2,3- CF₃ 5-yl triazol-4-yl 1894 2,4-(Me)₂Thiazol- 2-methyl-1,2,3- H 5-yl triazol-4-yl 1895 2,4-(Me)₂Thiazol- 2-methyl-1,2,3- methyl 5-yl triazol-4-yl 1896 2,4-(Me)₂Thiazol- 2-methyl-1,2,3- i-propyl 5-yl triazol-4-yl 1897 2,4-(Me)₂Thiazol- 2-methyl-1,2,3- cyclopropyl 5-yl triazol-4-yl 1898 2,4-(Me)₂Thiazol- 2-methyl-1,2,3- CF₃ 5-yl triazol-4-yl 1899 2,4-(Me)₂Thiazol- 1,2,3-triazol-1-yl H 5-yl 1900 2,4-(Me)₂Thiazol- 1,2,3-triazol-1-yl methyl 5-yl 1901 2,4-(Me)₂Thiazol- 1,2,3-triazol-1-yl i-propyl 5-yl 1902 2,4-(Me)₂Thiazol- 1,2,3-triazol-1-yl cyclopropyl 5-yl 1903 2,4-(Me)₂Thiazol- 1,2,3-triazol-1-yl CF₃ 5-yl 1904 2,4-(Me)₂Thiazol- 1,2,3-triazol-2-yl H 5-yl 1905 2,4-(Me)₂Thiazol- 1,2,3-triazol-2-yl methyl 5-yl 1906 2,4-(Me)₂Thiazol- 1,2,3-triazol-2-yl i-propyl 5-yl 1907 2,4-(Me)₂Thiazol- 1,2,3-triazol-2-yl cyclopropyl 5-yl 1908 2,4-(Me)₂Thiazol- 1,2,3-triazol-2-yl CF₃ 5-yl 1909 2,4-(Me)₂Thiazol- 1,2,4-triazol-1-yl H 5-yl 1910 2,4-(Me)₂Thiazol- 1,2,4-triazol-1-yl methyl 5-yl 1911 2,4-(Me)₂Thiazol- 1,2,4-triazol-1-yl i-propyl 5-yl 1912 2,4-(Me)₂Thiazol- 1,2,4-triazol-1-yl cyclopropyl 5-yl 1913 2,4-(Me)₂Thiazol- 1,2,4-triazol-1-yl CF₃ 5-yl 1914 2,4-(Me)₂Thiazol- imidazol-2-yl H 5-yl 1915 2,4-(Me)₂Thiazol- imidazol-2-yl methyl 5-yl 1916 2,4-(Me)₂Thiazol- imidazol-2-yl i-propyl 5-yl 1917 2,4-(Me)₂Thiazol- imidazol-2-yl cyclopropyl 5-yl 1918 2,4-(Me)₂Thiazol- imidazol-2-yl CF₃ 5-yl 1919 2,4-(Me)₂Thiazol- imidazol-1-yl H 5-yl 1920 2,4-(Me)₂Thiazol- imidazol-1-yl methyl 5-yl 1921 2,4-(Me)₂Thiazol- imidazol-1-yl i-propyl 5-yl 1922 2,4-(Me)₂Thiazol- imidazol-1-yl cyclopropyl 5-yl 1923 2,4-(Me)₂Thiazol- imidazol-1-yl CF₃ 5-yl 1924 2,4-(Me)₂Thiazol- imidazol-4-yl H 5-yl 1925 2,4-(Me)₂Thiazol- imidazol-4-yl methyl 5-yl 1926 2,4-(Me)₂Thiazol- imidazol-4-yl i-propyl 5-yl 1927 2,4-(Me)₂Thiazol- imidazol-4-yl cyclopropyl 5-yl 1928 2,4-(Me)₂Thiazol- imidazol-4-yl CF₃ 5-yl 1929 2,4-(Me)₂Thiazol- thiazol-2-yl H 5-yl 1930 2,4-(Me)₂Thiazol- thiazol-2-yl methyl 5-yl 1931 2,4-(Me)₂Thiazol- thiazol-2-yl i-propyl 5-yl 1932 2,4-(Me)₂Thiazol- thiazol-2-yl cyclopropyl 5-yl 1933 2,4-(Me)₂Thiazol- thiazol-2-yl CF₃ 5-yl 1934 2,4-(Me)₂Thiazol- 4-methylthiazol- H 5-yl 2-yl 1935 2,4-(Me)₂Thiazol- 4-methylthiazol- methyl 5-yl 2-yl 1936 2,4-(Me)₂Thiazol- 4-methylthiazol- i-propyl 5-yl 2-yl 1937 2,4-(Me)₂Thiazol- 4-methylthiazol- cyclopropyl 5-yl 2-yl 1938 2,4-(Me)₂Thiazol- 4-methylthiazol- CF₃ 5-yl 2-yl 1939 2,4-(Me)₂Thiazol- oxazol-2-yl H 5-yl 1940 2,4-(Me)₂Thiazol- oxazol-2-yl methyl 5-yl 1941 2,4-(Me)₂Thiazol- oxazol-2-yl i-propyl 5-yl 1942 2,4-(Me)₂Thiazol- oxazol-2-yl cyclopropyl 5-yl 1943 2,4-(Me)₂Thiazol- oxazol-2-yl CF₃ 5-yl 1944 2,4-(Me)₂Thiazol- 4,5-dimethyl- H 5-yl oxazol-2-yl 1945 2,4-(Me)₂Thiazol- 4,5-dimethyl- methyl 5-yl oxazol-2-yl 1946 2,4-(Me)₂Thiazol- 4,5-dimethyl- i-propyl 5-yl oxazol-2-yl 1947 2,4-(Me)₂Thiazol- 4,5-dimethyl- cyclopropyl 5-yl oxazol-2-yl 1948 2,4-(Me)₂Thiazol- 4,5-dimethyl- CF₃ 5-yl oxazol-2-yl 1949 2,4-(Me)₂Thiazol- 2-oxazolin-2-yl H 5-yl 1950 2,4-(Me)₂Thiazol- 2-oxazolin-2-yl methyl 5-yl 1951 2,4-(Me)₂Thiazol- 2-oxazolin-2-yl i-propyl 5-yl 1952 2,4-(Me)₂Thiazol- 2-oxazolin-2-yl cyclopropyl 5-yl 1953 2,4-(Me)₂Thiazol- 2-oxazolin-2-yl CF₃ 5-yl 1954 2,4-(Me)₂Thiazol- 4,4-dimethyl-2- H 5-yl oxazolin-2-yl 1955 2,4-(Me)₂Thiazol- 4,4-dimethyl-2- methyl 5-yl oxazolin-2-yl 1956 2,4-(Me)₂Thiazol- 4,4-dimethyl-2- i-propyl 5-yl oxazolin-2-yl 1957 2,4-(Me)₂Thiazol- 4,4-dimethyl-2- cyclopropyl 5-yl oxazolin-2-yl 1958 2,4-(Me)₂Thiazol- 4,4-dimethyl-2- CF₃ 5-yl oxazolin-2-yl 1959 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- H 5-yl 5-yl 1960 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- methyl 5-yl 5-yl 1961 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- i-propyl 5-yl 5-yl 1962 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- cyclopropyl 5-yl 5-yl 1963 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- CF₃ 5-yl 5-yl 1964 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- H 5-yl thiadiazol-5-yl 1965 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- methyl 5-yl thiadiazol-5-yl 1966 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- i-propyl 5-yl thiadiazol-5-yl 1967 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- cyclopropyl 5-yl thiadiazol-5-yl 1968 2,4-(Me)₂Thiazol- 3-methyl-1,2,4- CF₃ 5-yl thiadiazol-5-yl 1969 2,4-(Me)₂Thiazol- 3-trifluoromethyl- H 5-yl 1,2,4-thiadiazol- 5-yl 1970 2,4-(Me)₂Thiazol- 3-trifluoromethyl- methyl 5-yl 1,2,4-thiadiazol- 5-yl 1971 2,4-(Me)₂Thiazol- 3-trifluoromethyl- i-propyl 5-yl 1,2,4-thiadiazol- 5-yl 1972 2,4-(Me)₂Thiazol- 3-trifluoromethyl- cyclopropyl 5-yl 1,2,4-thiadiazol- 5-yl 1973 2,4-(Me)₂Thiazol- 3-trifluoromethyl- CF₃ 5-yl 1,2,4-thiadiazol- 5-yl 1974 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- H 5-yl 3-yl 1975 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- methyl 5-yl 3-yl 1976 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- i-propyl 5-yl 3-yl 1977 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- cyclopropyl 5-yl 3-yl 1978 2,4-(Me)₂Thiazol- 1,2,4-thiadiazol- CF₃ 5-yl 3-yl 1979 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- H 5-yl thiadiazol-3-yl 1980 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- methyl 5-yl thiadiazol-3-yl 1981 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- i-propyl 5-yl thiadiazol-3-yl 1982 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- cyclopropyl 5-yl thiadiazol-3-yl 1983 2,4-(Me)₂Thiazol- 5-methyl-1,2,4- CF₃ 5-yl thiadiazol-3-yl 1984 2,4-(Me)₂Thiazol- 5-trifluoromethyl- H 5-yl 1,2,4-thiadiazol- 3-yl 1985 2,4-(Me)₂Thiazol- 5-trifluoromethyl- methyl 5-yl 1,2,4-thiadiazol- 3-yl 1986 2,4-(Me)₂Thiazol- 5-trifluoromethyl- i-propyl 5-yl 1,2,4-thiadiazol- 3-yl 1987 2,4-(Me)₂Thiazol- 5-trifluoromethyl- cyclopropyl 5-yl 1,2,4-thiadiazol- 3-yl 1988 2,4-(Me)₂Thiazol- 5-trifluoromethyl- CF₃ 5-yl 1,2,4-thiadiazol- 3-yl 1989 2,4-(Me)₂Thiazol- 1,3,4-thiadiazol- H 5-yl 2-yl 1990 2,4-(Me)₂Thiazol- 1,3,4-thiadiazol- methyl 5-yl 2-yl 1991 2,4-(Me)₂Thiazol- 1,3,4-thiadiazol- i-propyl 5-yl 2-yl 1992 2,4-(Me)₂Thiazol- 1,3,4-thiadiazol- cyclopropyl 5-yl 2-yl 1993 2,4-(Me)₂Thiazol- 1,3,4-thiadiazol- CF₃ 5-yl 2-yl 1994 2,4-(Me)₂Thiazol- 5-methylsulfonyl- H 5-yl 1,3,4-thiadiazol- 2-yl 1995 2,4-(Me)₂Thiazol- 5-methylsulfonyl- methyl 5-yl 1,3,4-thiadiazol- 2-yl 1996 2,4-(Me)₂Thiazol- 5-methylsulfonyl- i-propyl 5-yl 1,3,4-thiadiazol- 2-yl 1997 2,4-(Me)₂Thiazol- 5-methylsulfonyl- cyclopropyl 5-yl 1,3,4-thiadiazol- 2-yl 1998 2,4-(Me)₂Thiazol- 5-methylsulfonyl- CF₃ 5-yl 1,3,4-thiadiazol- 2-yl 1999 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- H 5-yl thiadiazol-2-yl 2000 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- methyl 5-yl thiadiazol-2-yl 2001 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- i-propyl 5-yl thiadiazol-2-yl 2002 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- cyclopropyl 5-yl thiadiazol-2-yl 2003 2,4-(Me)₂Thiazol- 5-methyl-1,3,4- CF₃ 5-yl thiadiazol-2-yl 2004 2,4-(Me)₂Thiazol- benzoxazol-2-yl H 5-yl 2005 2,4-(Me)₂Thiazol- benzoxazol-2-yl methyl 5-yl 2006 2,4-(Me)₂Thiazol- benzoxazol-2-yl i-propyl 5-yl 2007 2,4-(Me)₂Thiazol- benzoxazol-2-yl cyclopropyl 5-yl 2008 2,4-(Me)₂Thiazol- benzoxazol-2-yl CF₃ 5-yl 2009 2,4-(Me)₂Thiazol- 6-methyl- H 5-yl benzoxazol-2-yl 2010 2,4-(Me)₂Thiazol- 6-methyl- methyl 5-yl benzoxazol-2-yl 2011 2,4-(Me)₂Thiazol- 6-methyl- i-propyl 5-yl benzoxazol-2-yl 2012 2,4-(Me)₂Thiazol- 6-methyl- cyclopropyl 5-yl benzoxazol-2-yl 2013 2,4-(Me)₂Thiazol- 6-methyl- CF₃ 5-yl benzoxazol-2-yl 2014 2,4-(Me)₂Thiazol- benzothiazol-2-yl H 5-yl 2015 2,4-(Me)₂Thiazol- benzothiazol-2-yl methyl 5-yl 2016 2,4-(Me)₂Thiazol- benzothiazol-2-yl i-propyl 5-yl 2017 2,4-(Me)₂Thiazol- benzothiazol-2-yl cyclopropyl 5-yl 2018 2,4-(Me)₂Thiazol- benzothiazol-2-yl CF₃ 5-yl 2019 2,4-(Me)₂Thiazol- pyrazol-1-yl H 5-yl 2020 2,4-(Me)₂Thiazol- pyrazol-1-yl methyl 5-yl 2021 2,4-(Me)₂Thiazol- pyrazol-1-yl i-propyl 5-yl 2022 2,4-(Me)₂Thiazol- pyrazol-1-yl cyclopropyl 5-yl 2023 2,4-(Me)₂Thiazol- pyrazol-1-yl CF₃ 5-yl 2024 2,4-(Me)₂Thiazol- pyrazol-3-yl H 5-yl 2025 2,4-(Me)₂Thiazol- pyrazol-3-yl methyl 5-yl 2026 2,4-(Me)₂Thiazol- pyrazol-3-yl i-propyl 5-yl 2027 2,4-(Me)₂Thiazol- pyrazol-3-yl cyclopropyl 5-yl 2028 2,4-(Me)₂Thiazol- pyrazol-3-yl CF₃ 5-yl 2029 2,4-(Me)₂Thiazol- 1-methylpyrazol- H 5-yl 3-yl 2030 2,4-(Me)₂Thiazol- 1-methylpyrazol- methyl 5-yl 3-yl 2031 2,4-(Me)₂Thiazol- 1-methylpyrazol- i-propyl 5-yl 3-yl 2032 2,4-(Me)₂Thiazol- 1-methylpyrazol- cyclopropyl 5-yl 3-yl 2033 2,4-(Me)₂Thiazol- 1-methylpyrazol- CF₃ 5-yl 3-yl 2034 2,4-(Me)₂Thiazol- tetrazol-1-yl H 5-yl 2035 2,4-(Me)₂Thiazol- tetrazol-1-yl methyl 5-yl 2036 2,4-(Me)₂Thiazol- tetrazol-1-yl i-propyl 5-yl 2037 2,4-(Me)₂Thiazol- tetrazol-1-yl cyclopropyl 5-yl 2038 2,4-(Me)₂Thiazol- tetrazol-1-yl CF₃ 5-yl 2039 2,4-(Me)₂Thiazol- 5-methyltetrazol- H 5-yl 1-yl 2040 2,4-(Me)₂Thiazol- 5-methyltetrazol- methyl 5-yl 1-yl 2041 2,4-(Me)₂Thiazol- 5-methyltetrazol- i-propyl 5-yl 1-yl 2042 2,4-(Me)₂Thiazol- 5-methyltetrazol- cyclopropyl 5-yl 1-yl 2043 2,4-(Me)₂Thiazol- 5-methyltetrazol- CF₃ 5-yl 1-yl 2044 2,4-(Me)₂Thiazol- tetrazol-2-yl H 5-yl 2045 2,4-(Me)₂Thiazol- tetrazol-2-yl methyl 5-yl 2046 2,4-(Me)₂Thiazol- tetrazol-2-yl i-propyl 5-yl 2047 2,4-(Me)₂Thiazol- tetrazol-2-yl cyclopropyl 5-yl 2048 2,4-(Me)₂Thiazol- tetrazol-2-yl CF₃ 5-yl 2049 2,4-(Me)₂Thiazol- 5-methyltetrazol- H 5-yl 2-yl 2050 2,4-(Me)₂Thiazol- 5-methyltetrazol- methyl 5-yl 2-yl 2051 2,4-(Me)₂Thiazol- 5-methyltetrazol- i-propyl 5-yl 2-yl 2052 2,4-(Me)₂Thiazol- 5-methyltetrazol- cyclopropyl 5-yl 2-yl 2053 2,4-(Me)₂Thiazol- 5-methyltetrazol- CF₃ 5-yl 2-yl 2054 2,4-(Me)₂Thiazol- 1-methyltetrazol- H 5-yl 5-yl 2055 2,4-(Me)₂Thiazol- 1-methyltetrazol- methyl 5-yl 5-yl 2056 2,4-(Me)₂Thiazol- 1-methyltetrazol- i-propyl 5-yl 5-yl 2057 2,4-(Me)₂Thiazol- 1-methyltetrazol- cyclopropyl 5-yl 5-yl 2058 2,4-(Me)₂Thiazol- 1-methyltetrazol- CF₃ 5-yl 5-yl 2059 2,4-(Me)₂Thiazol- 2-methyltetrazol- H 5-yl 5-yl 2060 2,4-(Me)₂Thiazol- 2-methyltetrazol- methyl 5-yl 5-yl 2061 2,4-(Me)₂Thiazol- 2-methyltetrazol- i-propyl 5-yl 5-yl 2062 2,4-(Me)₂Thiazol- 2-methyltetrazol- cyclopropyl 5-yl 5-yl 2063 2,4-(Me)₂Thiazol- 2-methyltetrazol- CF₃ 5-yl 5-yl 2064 2,4-(Me)₂Thiazol- pyridin-2-yl H 5-yl 2065 2,4-(Me)₂Thiazol- pyridin-2-yl methyl 5-yl 2066 2,4-(Me)₂Thiazol- pyridin-2-yl i-propyl 5-yl 2067 2,4-(Me)₂Thiazol- pyridin-2-yl cyclopropyl 5-yl 2068 2,4-(Me)₂Thiazol- pyridin-2-yl CF₃ 5-yl 2069 2,4-(Me)₂Thiazol- pyridin-4-yl H 5-yl 2070 2,4-(Me)₂Thiazol- pyridin-4-yl methyl 5-yl 2071 2,4-(Me)₂Thiazol- pyridin-4-yl i-propyl 5-yl 2072 2,4-(Me)₂Thiazol- pyridin-4-yl cyclopropyl 5-yl 2073 2,4-(Me)₂Thiazol- pyridin-4-yl CF₃ 5-yl 2074 2,4-(Me)₂Thiazol- pyridin-3-yl H 5-yl 2075 2,4-(Me)₂Thiazol- pyridin-3-yl methyl 5-yl 2076 2,4-(Me)₂Thiazol- pyridin-3-yl i-propyl 5-yl 2077 2,4-(Me)₂Thiazol- pyridin-3-yl cyclopropyl 5-yl 2078 2,4-(Me)₂Thiazol- pyridin-3-yl CF₃ 5-yl 2079 2,4-(Me)₂Thiazol- 3-nitropyridin- H 5-yl 4-yl 2080 2,4-(Me)₂Thiazol- 3-nitropyridin- methyl 5-yl 4-yl 2081 2,4-(Me)₂Thiazol- 3-nitropyridin- i-propyl 5-yl 4-yl 2082 2,4-(Me)₂Thiazol- 3-nitropyridin- cyclopropyl 5-yl 4-yl 2083 2,4-(Me)₂Thiazol- 3-nitropyridin- CF₃ 5-yl 4-yl 2084 2,4-(Me)₂Thiazol- 5-cyanopyridin- H 5-yl 2-yl 2085 2,4-(Me)₂Thiazol- 5-cyanopyridin- methyl 5-yl 2-yl 2086 2,4-(Me)₂Thiazol- 5-cyanopyridin- i-propyl 5-yl 2-yl 2087 2,4-(Me)₂Thiazol- 5-cyanopyridin- cyclopropyl 5-yl 2-yl 2088 2,4-(Me)₂Thiazol- 5-cyanopyridin- CF₃ 5-yl 2-yl 2089 2,4-(Me)₂Thiazol- 5-trifluoro- H 5-yl methylpyridin- 2-yl 2090 2,4-(Me)₂Thiazol- 5-trifluoro- methyl 5-yl methylpyridin- 2-yl 2091 2,4-(Me)₂Thiazol- 5-trifluoro- i-propyl 5-yl methylpyridin- 2-yl 2092 2,4-(Me)₂Thiazol- 5-trifluoro- cyclopropyl 5-yl methylpyridin- 2-yl 2093 2,4-(Me)₂Thiazol- 5-trifluoro- CF₃ 5-yl methylpyridin- 2-yl 2094 2,4-(Me)₂Thiazol- pyrimidin-2-yl H 5-yl 2095 2,4-(Me)₂Thiazol- pyrimidin-2-yl methyl 5-yl 2096 2,4-(Me)₂Thiazol- pyrimidin-2-yl i-propyl 5-yl 2097 2,4-(Me)₂Thiazol- pyrimidin-2-yl cyclopropyl 5-yl 2098 2,4-(Me)₂Thiazol- pyrimidin-2-yl CF₃ 5-yl 2099 2,4-(Me)₂Thiazol- pyrimidin-4-yl H 5-yl 2100 2,4-(Me)₂Thiazol- pyrimidin-4-yl methyl 5-yl 2101 2,4-(Me)₂Thiazol- pyrimidin-4-yl i-propyl 5-yl 2102 2,4-(Me)₂Thiazol- pyrimidin-4-yl cyclopropyl 5-yl 2103 2,4-(Me)₂Thiazol- pyrimidin-4-yl CF₃ 5-yl 2104 2,4-(Me)₂Thiazol- 6-chloro- methyl 5-yl pyrimidin-4-yl 2105 2,4-(Me)₂Thiazol- 6-chloro- i-propyl 5-yl pyrimidin-4-yl 2106 2,4-(Me)₂Thiazol- 6-chloro- cyclopropyl 5-yl pyrimidin-4-yl 2107 2,4-(Me)₂Thiazol- 6-chloro- CF₃ 5-yl pyrimidin-4-yl 2108 2,4-(Me)₂Thiazol- pyridazin-3-yl H 5-yl 2109 2,4-(Me)₂Thiazol- pyridazin-3-yl methyl 5-yl 2110 2,4-(Me)₂Thiazol- pyridazin-3-yl i-propyl 5-yl 2111 2,4-(Me)₂Thiazol- pyridazin-3-yl cyclopropyl 5-yl 2112 2,4-(Me)₂Thiazol- pyridazin-3-yl CF₃ 5-yl 2113 2,4-(Me)₂Thiazol- 6-chloro- methyl 5-yl pyridazin-3-yl 2114 2,4-(Me)₂Thiazol- 6-chloro- i-propyl 5-yl pyridazin-3-yl 2115 2,4-(Me)₂Thiazol- 6-chloro- cyclopropyl 5-yl pyridazin-3-yl 2116 2,4-(Me)₂Thiazol- 6-chloro- CF₃ 5-yl pyridazin-3-yl 2117 2,4-(Me)₂Thiazol- pyrazin-2-yl methyl 5-yl 2118 2,4-(Me)₂Thiazol- pyrazin-2-yl i-propyl 5-yl 2119 2,4-(Me)₂Thiazol- pyrazin-2-yl cyclopropyl 5-yl 2120 2,4-(Me)₂Thiazol- pyrazin-2-yl CF₃ 5-yl 2121 2,4-(Me)₂Thiazol- triazin-2-yl methyl 5-yl 2122 2,4-(Me)₂Thiazol- triazin-2-yl i-propyl 5-yl 2123 2,4-(Me)₂Thiazol- triazin-2-yl cyclopropyl 5-yl 2124 2,4-(Me)₂Thiazol- triazin-2-yl CF₃ 5-yl 2125 2,4-(Me)₂Thiazol- quinolin-2-yl methyl 5-yl 2126 2,4-(Me)₂Thiazol- quinolin-2-yl i-propyl 5-yl 2127 2,4-(Me)₂Thiazol- quinolin-2-yl cyclopropyl 5-yl 2128 2,4-(Me)₂Thiazol- quinolin-2-yl CF₃ 5-yl 2129 2,4-(Me)₂Thiazol- 4,4,6-trimethyl- H 5-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 2130 2,4-(Me)₂Thiazol- 4,4,6-trimethyl- methyl 5-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 2131 2,4-(Me)₂Thiazol- 4,4,6-trimethyl- i-propyl 5-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 2132 2,4-(Me)₂Thiazol- 4,4,6-trimethyl- cyclopropyl 5-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 2133 2,4-(Me)₂Thiazol- 4,4,6-trimethyl- CF₃ 5-yl 5,6-dihydro-1, 3(4H)-oxazin-2-yl 2134 2,4-(Me)₂Thiazol- 2-oxazolidinon- H 5-yl 3-yl 2135 2,4-(Me)₂Thiazol- 2-oxazolidinon- methyl 5-yl 3-yl 2136 2,4-(Me)₂Thiazol- 2-oxazolidinon- i-propyl 5-yl 3-yl 2137 2,4-(Me)₂Thiazol- 2-oxazolidinon- cyclopropyl 5-yl 3-yl 2138 2,4-(Me)₂Thiazol- 2-oxazolidinon- CF₃ 5-yl 3-yl 2139 2,4-(Me)₂Thiazol- 2-pyrrolidinon- methyl 5-yl 1-yl 2140 2,4-(Me)₂Thiazol- 2-pyrrolidinon- i-propyl 5-yl 1-yl 2141 2,4-(Me)₂Thiazol- 2-pyrrolidinon- cyclopropyl 5-yl 1-yl 2142 2,4-(Me)₂Thiazol- 2-pyrrolidinon- CF₃ 5-yl 1-yl 2143 2,4-(Me)₂Thiazol- 3-methylisoxazol- methyl 5-yl 5-yl 2144 2,4-(Me)₂Thiazol- 3-methylisoxazol- i-propyl 5-yl 5-yl 2145 2,4-(Me)₂Thiazol- 3-methylisoxazol- cyclopropyl 5-yl 5-yl 2146 2,4-(Me)₂Thiazol- 3-methylisoxazol- CF₃ 5-yl 5-yl 2147 2,4-(Me)₂Thiazol- 2-NO₂-4- H 5-yl SO₂MePh 2148 2,4-(Me)₂Thiazol- 2-NO₂-4- methyl 5-yl SO₂MePh 2149 2,4-(Me)₂Thiazol- 2-NO₂-4- i-propyl 5-yl SO₂MePh 2150 2,4-(Me)₂Thiazol- 2-NO₂-4- cyclopropyl 5-yl SO₂MePh 2151 2,4-(Me)₂Thiazol- 2-NO₂-4- CF₃ 5-yl SO₂MePh 2152 2,4-(Me)₂Thiazol- 2-Cl-4-SO₂MePH H 5-yl 2153 2,4-(Me)₂Thiazol- 2-Cl-4-SO₂MePH methyl 5-yl 2154 2,4-(Me)₂Thiazol- 2-Cl-4-SO₂MePH i-propyl 5-yl 2155 2,4-(Me)₂Thiazol- 2-Cl-4-SO₂MePH cyclopropyl 5-yl 2156 2,4-(Me)₂Thiazol- 2-Cl-4-SO₂MePH CF₃ 5-yl 2157 2,4-(Me)₂Thiazol- 2-NO₂-4-CF₃Ph H 5-yl 2158 2,4-(Me)₂Thiazol- 2-NO₂-4-CF₃Ph methyl 5-yl 2159 2,4-(Me)₂Thiazol- 2-NO₂-4-CF₃Ph i-propyl 5-yl 2160 2,4-(Me)₂Thiazol- 2-NO₂-4-CF₃Ph cyclopropyl 5-yl 2161 2,4-(Me)₂Thiazol- 2-NO₂-4-CF₃Ph CF₃ 5-yl 2162 2,4-(Me)₂Thiazol- 2-NO₂-4-ClPh H 5-yl 2163 2,4-(Me)₂Thiazol- 2-NO₂-4-ClPh methyl 5-yl 2164 2,4-(Me)₂Thiazol- 2-NO₂-4-ClPh i-propyl 5-yl 2165 2,4-(Me)₂Thiazol- 2-NO₂-4-ClPh cyclopropyl 5-yl 2166 2,4-(Me)₂Thiazol- 2-NO₂-4-ClPh CF₃ 5-yl 2167 2,4-(Me)₂Thiazol- 2-Cl-4-NO₂Ph H 5-yl 2168 2,4-(Me)₂Thiazol- 2-Cl-4-NO₂Ph methyl 5-yl 2169 2,4-(Me)₂Thiazol- 2-Cl-4-NO₂Ph i-propyl 5-yl 2170 2,4-(Me)₂Thiazol- 2-Cl-4-NO₂Ph cyclopropyl 5-yl 2171 2,4-(Me)₂Thiazol- 2-Cl-4-NO₂Ph CF₃ 5-yl 2172 2,4-(Me)₂Thiazol- 2,4-(NO₂)₂Ph H 5-yl 2173 2,4-(Me)₂Thiazol- 2,4-(NO₂)₂Ph methyl 5-yl 2174 2,4-(Me)₂Thiazol- 2,4-(NO₂)₂Ph i-propyl 5-yl 2175 2,4-(Me)₂Thiazol- 2,4-(NO₂)₂Ph cyclopropyl 5-yl 2176 2,4-(Me)₂Thiazol- 2,4-(NO₂)₂Ph CF₃ 5-yl 2177 2,4-(Me)₂Thiazol- 4-F-3-NO₂Ph H 5-yl 2178 2,4-(Me)₂Thiazol- 4-F-3-NO₂Ph methyl 5-yl 2179 2,4-(Me)₂Thiazol- 4-F-3-NO₂Ph i-propyl 5-yl 2180 2,4-(Me)₂Thiazol- 4-F-3-NO₂Ph cyclopropyl 5-yl 2181 2,4-(Me)₂Thiazol- 4-F-3-NO₂Ph CF₃ 5-yl 2182 2,4-(Me)₂Thiazol- 3,5-(CF₃)₂Ph H 5-yl 2183 2,4-(Me)₂Thiazol- 3,5-(CF₃)₂Ph methyl 5-yl 2184 2,4-(Me)₂Thiazol- 3,5-(CF₃)₂Ph i-propyl 5-yl 2185 2,4-(Me)₂Thiazol- 3,5-(CF₃)₂Ph cyclopropyl 5-yl 2186 2,4-(Me)₂Thiazol- 3,5-(CF₃)₂Ph CF₃ 5-yl 2187 2,4-(Me)₂Thiazol- 2-SO₂Me-4- H 5-yl CF₃Ph 2188 2,4-(Me)₂Thiazol- 2-SO₂Me-4- methyl 5-yl CF₃Ph 2189 2,4-(Me)₂Thiazol- 2-SO₂Me-4- i-propyl 5-yl CF₃Ph 2190 2,4-(Me)₂Thiazol- 2-SO₂Me-4- cyclopropyl 5-yl CF₃Ph 2191 2,4-(Me)₂Thiazol- 2-SO₂Me-4- CF₃ 5-yl CF₃Ph 2192 2-Me-4-SO₂Me- 1,2,4-oxadiazol- H 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2193 2-Me-4-SO₂Me- 1,2,4-oxadiazol- methyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2194 2-Me-4-SO₂Me- 1,2,4-oxadiazol- i-propyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2195 2-Me-4-SO₂Me- 1,2,4-oxadiazol- cyclopropyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2196 2-Me-4-SO₂Me- 1,2,4-oxadiazol- CF₃ 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2197 2-Me-4-SO₂Me- 3-methyl-1,2,4- H 3-(4,5-dihydro- oxadiazol-5-yl isoxazol-3-yl)Ph 2198 2-Me-4-SO₂Me- 3-methyl-1,2,4- methyl 3-(4,5-dihydro- oxadiazol-5-yl isoxazol-3-yl)Ph 2199 2-Me-4-SO₂Me- 3-methyl-1,2,4- i-propyl 3-(4,5-dihydro- oxadiazol-5-yl isoxazol-3-yl)Ph 2200 2-Me-4-SO₂Me- 3-methyl-1,2,4- cyclopropyl 3-(4,5-dihydro- oxadiazol-5-yl isoxazol-3-yl)Ph 2201 2-Me-4-SO₂Me- 3-methyl-1,2,4- CF₃ 3-(4,5-dihydro- oxadiazol-5-yl isoxazol-3-yl)Ph 2202 2-Me-4-SO₂Me- 3-trifluoromethyl- H 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 5-yl 2203 2-Me-4-SO₂Me- 3-trifluoromethyl- methyl 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 5-yl 2204 2-Me-4-SO₂Me- 3-trifluoromethyl- i-propyl 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 5-yl 2205 2-Me-4-SO₂Me- 3-trifluoromethyl- cyclopropyl 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 5-yl 2206 2-Me-4-SO₂Me- 3-trifluoromethyl- CF₃ 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 5-yl 2207 2-Me-4-SO₂Me- 1,2,4-oxadiazol- H 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2208 2-Me-4-SO₂Me- 1,2,4-oxadiazol- methyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2209 2-Me-4-SO₂Me- 1,2,4-oxadiazol- i-propyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2210 2-Me-4-SO₂Me- 1,2,4-oxadiazol- cyclopropyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2211 2-Me-4-SO₂Me- 1,2,4-oxadiazol- CF₃ 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2212 2-Me-4-SO₂Me- 5-methyl-1,2,4- H 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2213 2-Me-4-SO₂Me- 5-methyl-1,2,4- methyl 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2214 2-Me-4-SO₂Me- 5-methyl-1,2,4- i-propyl 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2215 2-Me-4-SO₂Me- 5-methyl-1,2,4- cyclopropyl 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2216 2-Me-4-SO₂Me- 5-methyl-1,2,4- CF₃ 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2217 2-Me-4-SO₂Me- 5-trifluoromethyl- H 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 3-yl 2218 2-Me-4-SO₂Me- 5-trifluoromethyl- methyl 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 3-yl 2219 2-Me-4-SO₂Me- 5-trifluoromethyl- i-propyl 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 3-yl 2220 2-Me-4-SO₂Me- 5-trifluoromethyl- cyclopropyl 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 3-yl 2221 2-Me-4-SO₂Me- 5-trifluoromethyl- CF₃ 3-(4,5-dihydro- 1,2,4-oxadiazol- isoxazol-3-yl)Ph 3-yl 2222 2-Me-4-SO₂Me- 5-chloro-1,2,4- H 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2223 2-Me-4-SO₂Me- 5-chloro-1,2,4- methyl 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2224 2-Me-4-SO₂Me- 5-chloro-1,2,4- i-propyl 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2225 2-Me-4-SO₂Me- 5-chloro-1,2,4- cyclopropyl 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2226 2-Me-4-SO₂Me- 5-chloro-1,2,4- CF₃ 3-(4,5-dihydro- oxadiazol-3-yl isoxazol-3-yl)Ph 2227 2-Me-4-SO₂Me- 1,3,4-oxadiazol- H 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2228 2-Me-4-SO₂Me- 1,3,4-oxadiazol- methyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2229 2-Me-4-SO₂Me- 1,3,4-oxadiazol- i-propyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2230 2-Me-4-SO₂Me- 1,3,4-oxadiazol- cyclopropyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2231 2-Me-4-SO₂Me- 1,3,4-oxadiazol- CF₃ 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2232 2-Me-4-SO₂Me- 5-methylsulfonyl- H 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2233 2-Me-4-SO₂Me- 5-methylsulfonyl- methyl 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2234 2-Me-4-SO₂Me- 5-methylsulfonyl- i-propyl 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2235 2-Me-4-SO₂Me- 5-methylsulfonyl- cyclopropyl 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2236 2-Me-4-SO₂Me- 5-methylsulfonyl- CF₃ 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2237 2-Me-4-SO₂Me- 5-methyl-1,3,4- H 3-(4,5-dihydro- oxadiazol-2-yl isoxazol-3-yl)Ph 2238 2-Me-4-SO₂Me- 5-methyl-1,3,4- methyl 3-(4,5-dihydro- oxadiazol-2-yl isoxazol-3-yl)Ph 2239 2-Me-4-SO₂Me- 5-methyl-1,3,4- i-propyl 3-(4,5-dihydro- oxadiazol-2-yl isoxazol-3-yl)Ph 2240 2-Me-4-SO₂Me- 5-methyl-1,3,4- cyclopropyl 3-(4,5-dihydro- oxadiazol-2-yl isoxazol-3-yl)Ph 2241 2-Me-4-SO₂Me- 5-methyl-1,3,4- CF₃ 3-(4,5-dihydro- oxadiazol-2-yl isoxazol-3-yl)Ph 2242 2-Me-4-SO₂Me- 5-trifluoromethyl- H 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2243 2-Me-4-SO₂Me- 5-trifluoromethyl- methyl 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2244 2-Me-4-SO₂Me- 5-trifluoromethyl- i-propyl 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2245 2-Me-4-SO₂Me- 5-trifluoromethyl- cyclopropyl 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2246 2-Me-4-SO₂Me- 5-trifluoromethyl- CF₃ 3-(4,5-dihydro- 1,3,4-oxadiazol- isoxazol-3-yl)Ph 2-yl 2247 2-Me-4-SO₂Me- 1,2,3-triazol-4-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2248 2-Me-4-SO₂Me- 1,2,3-triazol-4-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2249 2-Me-4-SO₂Me- 1,2,3-triazol-4-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2250 2-Me-4-SO₂Me- 1,2,3-triazol-4-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2251 2-Me-4-SO₂Me- 1,2,3-triazol-4-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2252 2-Me-4-SO₂Me- 1-methyl-1,2,3- H 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2253 2-Me-4-SO₂Me- 1-methyl-1,2,3- methyl 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2254 2-Me-4-SO₂Me- 1-methyl-1,2,3- i-propyl 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2255 2-Me-4-SO₂Me- 1-methyl-1,2,3- cyclopropyl 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2256 2-Me-4-SO₂Me- 1-methyl-1,2,3- CF₃ 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2257 2-Me-4-SO₂Me- 2-methyl-1,2,3- H 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2258 2-Me-4-SO₂Me- 2-methyl-1,2,3- methyl 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2259 2-Me-4-SO₂Me- 2-methyl-1,2,3- i-propyl 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2260 2-Me-4-SO₂Me- 2-methyl-1,2,3- cyclopropyl 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2261 2-Me-4-SO₂Me- 2-methyl-1,2,3- CF₃ 3-(4,5-dihydro- triazol-4-yl isoxazol-3-yl)Ph 2262 2-Me-4-SO₂Me- 1,2,3-triazol-1-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2263 2-Me-4-SO₂Me- 1,2,3-triazol-1-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2264 2-Me-4-SO₂Me- 1,2,3-triazol-1-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2265 2-Me-4-SO₂Me- 1,2,3-triazol-1-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2266 2-Me-4-SO₂Me- 1,2,3-triazol-1-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2267 2-Me-4-SO₂Me- 1,2,3-triazol-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2268 2-Me-4-SO₂Me- 1,2,3-triazol-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2269 2-Me-4-SO₂Me- 1,2,3-triazol-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2270 2-Me-4-SO₂Me- 1,2,3-triazol-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2271 2-Me-4-SO₂Me- 1,2,3-triazol-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2272 2-Me-4-SO₂Me- 1,2,4-triazol-1-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2273 2-Me-4-SO₂Me- 1,2,4-triazol-1-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2274 2-Me-4-SO₂Me- 1,2,4-triazol-1-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2275 2-Me-4-SO₂Me- 1,2,4-triazol-1-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2276 2-Me-4-SO₂Me- 1,2,4-triazol-1-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2277 2-Me-4-SO₂Me- imidazol-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2278 2-Me-4-SO₂Me- imidazol-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2279 2-Me-4-SO₂Me- imidazol-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2280 2-Me-4-SO₂Me- imidazol-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2281 2-Me-4-SO₂Me- imidazol-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2282 2-Me-4-SO₂Me- imidazol-1-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2283 2-Me-4-SO₂Me- imidazol-1-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2284 2-Me-4-SO₂Me- imidazol-1-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2285 2-Me-4-SO₂Me- imidazol-1-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2286 2-Me-4-SO₂Me- imidazol-1-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2287 2-Me-4-SO₂Me- imidazol-4-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2288 2-Me-4-SO₂Me- imidazol-4-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2289 2-Me-4-SO₂Me- imidazol-4-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2290 2-Me-4-SO₂Me- imidazol-4-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2291 2-Me-4-SO₂Me- imidazol-4-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2292 2-Me-4-SO₂Me- thiazol-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2293 2-Me-4-SO₂Me- thiazol-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2294 2-Me-4-SO₂Me- thiazol-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2295 2-Me-4-SO₂Me- thiazol-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2296 2-Me-4-SO₂Me- thiazol-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2297 2-Me-4-SO₂Me- 4-methylthiazol- H 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2298 2-Me-4-SO₂Me- 4-methylthiazol- methyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2299 2-Me-4-SO₂Me- 4-methylthiazol- i-propyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2300 2-Me-4-SO₂Me- 4-methylthiazol- cyclopropyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2301 2-Me-4-SO₂Me- 4-methylthiazol- CF₃ 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2302 2-Me-4-SO₂Me- oxazol-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2303 2-Me-4-SO₂Me- oxazol-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2304 2-Me-4-SO₂Me- oxazol-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2305 2-Me-4-SO₂Me- oxazol-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2306 2-Me-4-SO₂Me- oxazol-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2307 2-Me-4-SO₂Me- 4,5-dimethyl- H 3-(4,5-dihydro- oxazol-2-yl isoxazol-3-yl)Ph 2308 2-Me-4-SO₂Me- 4,5-dimethyl- methyl 3-(4,5-dihydro- oxazol-2-yl isoxazol-3-yl)Ph 2309 2-Me-4-SO₂Me- 4,5-dimethyl- i-propyl 3-(4,5-dihydro- oxazol-2-yl isoxazol-3-yl)Ph 2310 2-Me-4-SO₂Me- 4,5-dimethyl- cyclopropyl 3-(4,5-dihydro- oxazol-2-yl isoxazol-3-yl)Ph 2311 2-Me-4-SO₂Me- 4,5-dimethyl- CF₃ 3-(4,5-dihydro- oxazol-2-yl isoxazol-3-yl)Ph 2312 2-Me-4-SO₂Me- 2-oxazolin-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2313 2-Me-4-SO₂Me- 2-oxazolin-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2314 2-Me-4-SO₂Me- 2-oxazolin-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2315 2-Me-4-SO₂Me- 2-oxazolin-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2316 2-Me-4-SO₂Me- 2-oxazolin-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2317 2-Me-4-SO₂Me- 4,4-dimethyl-2- H 3-(4,5-dihydro- oxazolin-2-yl isoxazol-3-yl)Ph 2318 2-Me-4-SO₂Me- 4,4-dimethyl-2- methyl 3-(4,5-dihydro- oxazolin-2-yl isoxazol-3-yl)Ph 2319 2-Me-4-SO₂Me- 4,4-dimethyl-2- i-propyl 3-(4,5-dihydro- oxazolin-2-yl isoxazol-3-yl)Ph 2320 2-Me-4-SO₂Me- 4,4-dimethyl-2- cyclopropyl 3-(4,5-dihydro- oxazolin-2-yl isoxazol-3-yl)Ph 2321 2-Me-4-SO₂Me- 4,4-dimethyl-2- CF₃ 3-(4,5-dihydro- oxazolin-2-yl isoxazol-3-yl)Ph 2322 2-Me-4-SO₂Me- 1,2,4-thiadiazol- H 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2323 2-Me-4-SO₂Me- 1,2,4-thiadiazol- methyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2324 2-Me-4-SO₂Me- 1,2,4-thiadiazol- i-propyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2325 2-Me-4-SO₂Me- 1,2,4-thiadiazol- cyclopropyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2326 2-Me-4-SO₂Me- 1,2,4-thiadiazol- CF₃ 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2327 2-Me-4-SO₂Me- 3-methyl-1,2,4- H 3-(4,5-dihydro- thiadiazol-5-yl isoxazol-3-yl)Ph 2328 2-Me-4-SO₂Me- 3-methyl-1,2,4- methyl 3-(4,5-dihydro- thiadiazol-5-yl isoxazol-3-yl)Ph 2329 2-Me-4-SO₂Me- 3-methyl-1,2,4- i-propyl 3-(4,5-dihydro- thiadiazol-5-yl isoxazol-3-yl)Ph 2330 2-Me-4-SO₂Me- 3-methyl-1,2,4- cyclopropyl 3-(4,5-dihydro- thiadiazol-5-yl isoxazol-3-yl)Ph 2331 2-Me-4-SO₂Me- 3-methyl-1,2,4- CF₃ 3-(4,5-dihydro- thiadiazol-5-yl isoxazol-3-yl)Ph 2332 2-Me-4-SO₂Me- 3-trifluoromethyl- H 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 5-yl 2333 2-Me-4-SO₂Me- 3-trifluoromethyl- methyl 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 5-yl 2134 2-Me-4-SO₂Me- 3-trifluoromethyl- i-propyl 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 5-yl 2335 2-Me-4-SO₂Me- 3-trifluoromethyl- cyclopropyl 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 5-yl 2336 2-Me-4-SO₂Me- 3-trifluoromethyl- CF₃ 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 5-yl 2337 2-Me-4-SO₂Me- 1,2,4-thiadiazol- H 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2338 2-Me-4-SO₂Me- 1,2,4-thiadiazol- methyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2339 2-Me-4-SO₂Me- 1,2,4-thiadiazol- i-propyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2340 2-Me-4-SO₂Me- 1,2,4-thiadiazol- cyclopropyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2341 2-Me-4-SO₂Me- 1,2,4-thiadiazol- CF₃ 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2342 2-Me-4-SO₂Me- 5-methyl-1,2,4- H 3-(4,5-dihydro- thiadiazol-3-yl isoxazol-3-yl)Ph 2343 2-Me-4-SO₂Me- 5-methyl-1,2,4- methyl 3-(4,5-dihydro- thiadiazol-3-yl isoxazol-3-yl)Ph 2344 2-Me-4-SO₂Me- 5-methyl-1,2,4- i-propyl 3-(4,5-dihydro- thiadiazol-3-yl isoxazol-3-yl)Ph 2345 2-Me-4-SO₂Me- 5-methyl-1,2,4- cyclopropyl 3-(4,5-dihydro- thiadiazol-3-yl isoxazol-3-yl)Ph 2346 2-Me-4-SO₂Me- 5-methyl-1,2,4- CF₃ 3-(4,5-dihydro- thiadiazol-3-yl isoxazol-3-yl)Ph 2347 2-Me-4-SO₂Me- 5-trifluoromethyl- H 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 3-yl 2348 2-Me-4-SO₂Me- 5-trifluoromethyl- methyl 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 3-yl 2349 2-Me-4-SO₂Me- 5-trifluoromethyl- i-propyl 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 3-yl 2350 2-Me-4-SO₂Me- 5-trifluoromethyl- cyclopropyl 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 3-yl 2351 2-Me-4-SO₂Me- 5-trifluoromethyl- CF₃ 3-(4,5-dihydro- 1,2,4-thiadiazol- isoxazol-3-yl)Ph 3-yl 2352 2-Me-4-SO₂Me- 1,3,4-thiadiazol- H 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2353 2-Me-4-SO₂Me- 1,3,4-thiadiazol- methyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2354 2-Me-4-SO₂Me- 1,3,4-thiadiazol- i-propyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2355 2-Me-4-SO₂Me- 1,3,4-thiadiazol- cyclopropyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2356 2-Me-4-SO₂Me- 1,3,4-thiadiazol- CF₃ 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2357 2-Me-4-SO₂Me- 5-methylsulfonyl- H 3-(4,5-dihydro- 1,3,4-thiadiazol- isoxazol-3-yl)Ph 2-yl 2358 2-Me-4-SO₂Me- 5-methylsulfonyl- methyl 3-(4,5-dihydro- 1,3,4-thiadiazol- isoxazol-3-yl)Ph 2-yl 2359 2-Me-4-SO₂Me- 5-methylsulfonyl- i-propyl 3-(4,5-dihydro- 1,3,4-thiadiazol- isoxazol-3-yl)Ph 2-yl 2360 2-Me-4-SO₂Me- 5-methylsulfonyl- cyclopropyl 3-(4,5-dihydro- 1,3,4-thiadiazol- isoxazol-3-yl)Ph 2-yl 2361 2-Me-4-SO₂Me- 5-methylsulfonyl- CF₃ 3-(4,5-dihydro- 1,3,4-thiadiazol- isoxazol-3-yl)Ph 2-yl 2362 2-Me-4-SO₂Me- 5-methyl-1,3,4- H 3-(4,5-dihydro- thiadiazol-2-yl isoxazol-3-yl)Ph 2363 2-Me-4-SO₂Me- 5-methyl-1,3,4- methyl 3-(4,5-dihydro- thiadiazol-2-yl isoxazol-3-yl)Ph 2364 2-Me-4-SO₂Me- 5-methyl-1,3,4- i-propyl 3-(4,5-dihydro- thiadiazol-2-yl isoxazol-3-yl)Ph 2365 2-Me-4-SO₂Me- 5-methyl-1,3,4- cyclopropyl 3-(4,5-dihydro- thiadiazol-2-yl isoxazol-3-yl)Ph 2366 2-Me-4-SO₂Me- 5-methyl-1,3,4- CF₃ 3-(4,5-dihydro- thiadiazol-2-yl isoxazol-3-yl)Ph 2367 2-Me-4-SO₂Me- benzoxazol-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2368 2-Me-4-SO₂Me- benzoxazol-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2369 2-Me-4-SO₂Me- benzoxazol-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2370 2-Me-4-SO₂Me- benzoxazol-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2371 2-Me-4-SO₂Me- benzoxazol-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2372 2-Me-4-SO₂Me- 6-methyl- H 3-(4,5-dihydro- benzoxazol-2-yl isoxazol-3-yl)Ph 2373 2-Me-4-SO₂Me- 6-methyl- methyl 3-(4,5-dihydro- benzoxazol-2-yl isoxazol-3-yl)Ph 2374 2-Me-4-SO₂Me- 6-methyl- i-propyl 3-(4,5-dihydro- benzoxazol-2-yl isoxazol-3-yl)Ph 2375 2-Me-4-SO₂Me- 6-methyl- cyclopropyl 3-(4,5-dihydro- benzoxazol-2-yl isoxazol-3-yl)Ph 2376 2-Me-4-SO₂Me- 6-methyl- CF₃ 3-(4,5-dihydro- benzoxazol-2-yl isoxazol-3-yl)Ph 2377 2-Me-4-SO₂Me- benzothiazol-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2378 2-Me-4-SO₂Me- benzothiazol-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2379 2-Me-4-SO₂Me- benzothiazol-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2380 2-Me-4-SO₂Me- benzothiazol-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2381 2-Me-4-SO₂Me- benzothiazol-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2382 2-Me-4-SO₂Me- pyrazol-1-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2383 2-Me-4-SO₂Me- pyrazol-1-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2385 2-Me-4-SO₂Me- pyrazol-1-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2386 2-Me-4-SO₂Me- pyrazol-1-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2387 2-Me-4-SO₂Me- pyrazol-3-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2388 2-Me-4-SO₂Me- pyrazol-3-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2389 2-Me-4-SO₂Me- pyrazol-3-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2390 2-Me-4-SO₂Me- pyrazol-3-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2391 2-Me-4-SO₂Me- pyrazol-3-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2392 2-Me-4-SO₂Me- 1-methylpyrazol- H 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2393 2-Me-4-SO₂Me- 1-methylpyrazol- methyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2394 2-Me-4-SO₂Me- 1-methylpyrazol- i-propyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2395 2-Me-4-SO₂Me- 1-methylpyrazol- cyclopropyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2396 2-Me-4-SO₂Me- 1-methylpyrazol- CF₃ 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2397 2-Me-4-SO₂Me- tetrazol-1-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2398 2-Me-4-SO₂Me- tetrazol-1-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2399 2-Me-4-SO₂Me- tetrazol-1-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2400 2-Me-4-SO₂Me- tetrazol-1-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2401 2-Me-4-SO₂Me- tetrazol-1-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2402 2-Me-4-SO₂Me- 5-methyltetrazol- H 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2403 2-Me-4-SO₂Me- 5-methyltetrazol- methyl 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2404 2-Me-4-SO₂Me- 5-methyltetrazol- i-propyl 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2405 2-Me-4-SO₂Me- 5-methyltetrazol- cyclopropyl 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2406 2-Me-4-SO₂Me- 5-methyltetrazol- CF₃ 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2407 2-Me-4-SO₂Me- tetrazol-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2408 2-Me-4-SO₂Me- tetrazol-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2409 2-Me-4-SO₂Me- tetrazol-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2410 2-Me-4-SO₂Me- tetrazol-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2411 2-Me-4-SO₂Me- tetrazol-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2412 2-Me-4-SO₂Me- 5-methyltetrazol- H 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2413 2-Me-4-SO₂Me- 5-methyltetrazol- methyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2414 2-Me-4-SO₂Me- 5-methyltetrazol- i-propyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2415 2-Me-4-SO₂Me- 5-methyltetrazol- cyclopropyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2416 2-Me-4-SO₂Me- 5-methyltetrazol- CF₃ 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2417 2-Me-4-SO₂Me- 1-methyltetrazol- H 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2418 2-Me-4-SO₂Me- 1-methyltetrazol- methyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2419 2-Me-4-SO₂Me- 1-methyltetrazol- i-propyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2420 2-Me-4-SO₂Me- 1-methyltetrazol- cyclopropyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2421 2-Me-4-SO₂Me- 1-methyltetrazol- CF₃ 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2422 2-Me-4-SO₂Me- 2-methyltetrazol- H 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2423 2-Me-4-SO₂Me- 2-methyltetrazol- methyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2424 2-Me-4-SO₂Me- 2-methyltetrazol- i-propyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2425 2-Me-4-SO₂Me- 2-methyltetrazol- cyclopropyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2426 2-Me-4-SO₂Me- 2-methyltetrazol- CF₃ 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2427 2-Me-4-SO₂Me- pyridin-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2428 2-Me-4-SO₂Me- pyridin-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2429 2-Me-4-SO₂Me- pyridin-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2430 2-Me-4-SO₂Me- pyridin-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2431 2-Me-4-SO₂Me- pyridin-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2432 2-Me-4-SO₂Me- pyridin-4-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2433 2-Me-4-SO₂Me- pyridin-4-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2434 2-Me-4-SO₂Me- pyridin-4-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2435 2-Me-4-SO₂Me- pyridin-4-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2436 2-Me-4-SO₂Me- pyridin-4-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2437 2-Me-4-SO₂Me- pyridin-3-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2438 2-Me-4-SO₂Me- pyridin-3-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2439 2-Me-4-SO₂Me- pyridin-3-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2440 2-Me-4-SO₂Me- pyridin-3-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2441 2-Me-4-SO₂Me- pyridin-3-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2442 2-Me-4-SO₂Me- 3-nitropyridin- H 3-(4,5-dihydro- 4-yl isoxazol-3-yl)Ph 2443 2-Me-4-SO₂Me- 3-nitropyridin- methyl 3-(4,5-dihydro- 4-yl isoxazol-3-yl)Ph 2444 2-Me-4-SO₂Me- 3-nitropyridin- i-propyl 3-(4,5-dihydro- 4-yl isoxazol-3-yl)Ph 2445 2-Me-4-SO₂Me- 3-nitropyridin- cyclopropyl 3-(4,5-dihydro- 4-yl isoxazol-3-yl)Ph 2446 2-Me-4-SO₂Me- 3-nitropyridin- CF₃ 3-(4,5-dihydro- 4-yl isoxazol-3-yl)Ph 2447 2-Me-4-SO₂Me- 5-cyanopyridin- H 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2448 2-Me-4-SO₂Me- 5-cyanopyridin- methyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2449 2-Me-4-SO₂Me- 5-cyanopyridin- i-propyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2450 2-Me-4-SO₂Me- 5-cyanopyridin- cyclopropyl 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2451 2-Me-4-SO₂Me- 5-cyanopyridin- CF₃ 3-(4,5-dihydro- 2-yl isoxazol-3-yl)Ph 2452 2-Me-4-SO₂Me- 5-trifluoro- H 3-(4,5-dihydro- methylpyridin- isoxazol-3-yl)Ph 2-yl 2453 2-Me-4-SO₂Me- 5-trifluoro- methyl 3-(4,5-dihydro- methylpyridin- isoxazol-3-yl)Ph 2-yl 2454 2-Me-4-SO₂Me- 5-trifluoro- i-propyl 3-(4,5-dihydro- methylpyridin- isoxazol-3-yl)Ph 2-yl 2455 2-Me-4-SO₂Me- 5-trifluoro- cyclopropyl 3-(4,5-dihydro- methylpyridin- isoxazol-3-yl)Ph 2-yl 2456 2-Me-4-SO₂Me- 5-trifluoro- CF₃ 3-(4,5-dihydro- methylpyridin- isoxazol-3-yl)Ph 2-yl 2457 2-Me-4-SO₂Me- pyrimidin-2-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2458 2-Me-4-SO₂Me- pyrimidin-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2459 2-Me-4-SO₂Me- pyrimidin-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2460 2-Me-4-SO₂Me- pyrimidin-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2461 2-Me-4-SO₂Me- pyrimidin-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2462 2-Me-4-SO₂Me- pyrimidin-4-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2463 2-Me-4-SO₂Me- pyrimidin-4-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2464 2-Me-4-SO₂Me- pyrimidin-4-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2465 2-Me-4-SO₂Me- pyrimidin-4-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2466 2-Me-4-SO₂Me- pyrimidin-4-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2467 2-Me-4-SO₂Me- 6-chloro- methyl 3-(4,5-dihydro- pyrimidin-4-yl isoxazol-3-yl)Ph 2468 2-Me-4-SO₂Me- 6-chloro- i-propyl 3-(4,5-dihydro- pyrimidin-4-yl isoxazol-3-yl)Ph 2469 2-Me-4-SO₂Me- 6-chloro- cyclopropyl 3-(4,5-dihydro- pyrimidin-4-yl isoxazol-3-yl)Ph 2470 2-Me-4-SO₂Me- 6-chloro- CF₃ 3-(4,5-dihydro- pyrimidin-4-yl isoxazol-3-yl)Ph 2471 2-Me-4-SO₂Me- pyridazin-3-yl H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2472 2-Me-4-SO₂Me- pyridazin-3-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2473 2-Me-4-SO₂Me- pyridazin-3-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2474 p2-Me-4-SO₂Me- yridazin-3-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2475 p2-Me-4-SO₂Me- yridazin-3-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2476 2-Me-4-SO₂Me- 6-chloro- methyl 3-(4,5-dihydro- pyridazin-3-yl isoxazol-3-yl)Ph 2477 2-Me-4-SO₂Me- 6-chloro- i-propyl 3-(4,5-dihydro- pyridazin-3-yl isoxazol-3-yl)Ph 2478 2-Me-4-SO₂Me- 6-chloro- cyclopropyl 3-(4,5-dihydro- pyridazin-3-yl isoxazol-3-yl)Ph 2479 2-Me-4-SO₂Me- 6-chloro- CF₃ 3-(4,5-dihydro- pyridazin-3-yl isoxazol-3-yl)Ph 2480 2-Me-4-SO₂Me- pyrazin-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2481 2-Me-4-SO₂Me- pyrazin-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2482 2-Me-4-SO₂Me- pyrazin-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2483 2-Me-4-SO₂Me- pyrazin-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2484 2-Me-4-SO₂Me- triazin-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2485 2-Me-4-SO₂Me- triazin-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2486 2-Me-4-SO₂Me- triazin-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2487 2-Me-4-SO₂Me- triazin-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2488 2-Me-4-SO₂Me- quinolin-2-yl methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2489 2-Me-4-SO₂Me- quinolin-2-yl i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2490 2-Me-4-SO₂Me- quinolin-2-yl cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2491 2-Me-4-SO₂Me- quinolin-2-yl CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2492 2-Me-4-SO₂Me- 4,4,6-trimethyl- H 3-(4,5-dihydro- 5,6-dihydro-1, isoxazol-3-yl)Ph 3(4H)-oxazin-2-yl 2493 2-Me-4-SO₂Me- 4,4,6-trimethyl- methyl 3-(4,5-dihydro- 5,6-dihydro-1, isoxazol-3-yl)Ph 3(4H)-oxazin-2-yl 2494 2-Me-4-SO₂Me- 4,4,6-trimethyl- i-propyl 3-(4,5-dihydro- 5,6-dihydro-1, isoxazol-3-yl)Ph 3(4H)-oxazin-2-yl 2495 2-Me-4-SO₂Me- 4,4,6-trimethyl- cyclopropyl 3-(4,5-dihydro- 5,6-dihydro-1, isoxazol-3-yl)Ph 3(4H)-oxazin-2-yl 2496 2-Me-4-SO₂Me- 4,4,6-trimethyl- CF₃ 3-(4,5-dihydro- 5,6-dihydro-1, isoxazol-3-yl)Ph 3(4H)-oxazin-2-yl 2497 2-Me-4-SO₂Me- 2-oxazolidinon- H 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2498 2-Me-4-SO₂Me- 2-oxazolidinon- methyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2499 2-Me-4-SO₂Me- 2-oxazolidinon- i-propyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2500 2-Me-4-SO₂Me- 2-oxazolidinon- cyclopropyl 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2501 2-Me-4-SO₂Me- 2-oxazolidinon- CF₃ 3-(4,5-dihydro- 3-yl isoxazol-3-yl)Ph 2502 2-Me-4-SO₂Me- 2-pyrrolidinon- methyl 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2503 2-Me-4-SO₂Me- 2-pyrrolidinon- i-propyl 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2504 2-Me-4-SO₂Me- 2-pyrrolidinon- cyclopropyl 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2505 2-Me-4-SO₂Me- 2-pyrrolidinon- CF₃ 3-(4,5-dihydro- 1-yl isoxazol-3-yl)Ph 2506 2-Me-4-SO₂Me- 3-methylisoxazol- methyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2507 2-Me-4-SO₂Me- 3-methylisoxazol- i-propyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2508 2-Me-4-SO₂Me- 3-methylisoxazol- cyclopropyl 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2509 2-Me-4-SO₂Me- 3-methylisoxazol- CF₃ 3-(4,5-dihydro- 5-yl isoxazol-3-yl)Ph 2510 2-Me-4-SO₂Me- 2-NO₂-4- H 3-(4,5-dihydro- SO₂MePh isoxazol-3-yl)Ph 2511 2-Me-4-SO₂Me- 2-NO₂-4- methyl 3-(4,5-dihydro- SO₂MePh isoxazol-3-yl)Ph 2512 2-Me-4-SO₂Me- 2-NO₂-4- i-propyl 3-(4,5-dihydro- SO₂MePh isoxazol-3-yl)Ph 2513 2-Me-4-SO₂Me- 2-NO₂-4- cyclopropyl 3-(4,5-dihydro- SO₂MePh isoxazol-3-yl)Ph 2514 2-Me-4-SO₂Me- 2-NO₂-4- CF₃ 3-(4,5-dihydro- SO₂MePh isoxazol-3-yl)Ph 2515 2-Me-4-SO₂Me- 2-Cl-4-SO₂MePh H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2516 2-Me-4-SO₂Me- 2-Cl-4-SO₂MePh methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2517 2-Me-4-SO₂Me- 2-Cl-4-SO₂MePh i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2518 2-Me-4-SO₂Me- 2-Cl-4-SO₂MePh cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2519 2-Me-4-SO₂Me- 2-Cl-4-SO₂MePh CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2520 2-Me-4-SO₂Me- 2-NO₂-4-CF₃Ph H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2521 2-Me-4-SO₂Me- 2-NO₂-4-CF₃Ph methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2522 2-Me-4-SO₂Me- 2-NO₂-4-CF₃Ph i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2523 2-Me-4-SO₂Me- 2-NO₂-4-CF₃Ph cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2524 2-Me-4-SO₂Me- 2-NO₂-4-CF₃Ph CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2525 2-Me-4-SO₂Me- 2-NO₂-4-ClPh H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2526 2-Me-4-SO₂Me- 2-NO₂-4-ClPh methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2527 2-Me-4-SO₂Me- 2-NO₂-4-ClPh i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2528 2-Me-4-SO₂Me- 2-NO₂-4-ClPh cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2529 2-Me-4-SO₂Me- 2-NO₂-4-ClPh CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2530 2-Me-4-SO₂Me- 2-Cl-4-NO₂Ph H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2531 2-Me-4-SO₂Me- 2-Cl-4-NO₂Ph methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2532 2-Me-4-SO₂Me- 2-Cl-4-NO₂Ph i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2533 2-Me-4-SO₂Me- 2-Cl-4-NO₂Ph cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2534 2-Me-4-SO₂Me- 2-Cl-4-NO₂Ph CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2535 2-Me-4-SO₂Me- 2,4-(NO₂)₂Ph H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2536 2-Me-4-SO₂Me- 2,4-(NO₂)₂Ph methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2537 2-Me-4-SO₂Me- 2,4-(NO₂)₂Ph i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2538 2-Me-4-SO₂Me- 2,4-(NO₂)₂Ph cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2539 2-Me-4-SO₂Me- 2,4-(NO₂)₂Ph CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2540 2-Me-4-SO₂Me- 4-F-3-NO₂Ph H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2541 2-Me-4-SO₂Me- 4-F-3-NO₂Ph methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2542 2-Me-4-SO₂Me- 4-F-3-NO₂Ph i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2543 2-Me-4-SO₂Me- 4-F-3-NO₂Ph cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2544 2-Me-4-SO₂Me- 4-F-3-NO₂Ph CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2545 2-Me-4-SO₂Me- 3,5-(CF₃)₂Ph H 3-(4,5-dihydro- isoxazol-3-yl)Ph 2546 2-Me-4-SO₂Me- 3,5-(CF₃)₂Ph methyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2547 2-Me-4-SO₂Me- 3,5-(CF₃)₂Ph i-propyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2548 2-Me-4-SO₂Me- 3,5-(CF₃)₂Ph cyclopropyl 3-(4,5-dihydro- isoxazol-3-yl)Ph 2549 2-Me-4-SO₂Me- 3,5-(CF₃)₂Ph CF₃ 3-(4,5-dihydro- isoxazol-3-yl)Ph 2550 2-Me-4-SO₂Me- 2-SO₂Me-4- H 3-(4,5-dihydro- CF₃Ph isoxazol-3-yl)Ph 2551 2-Me-4-SO₂Me- 2-SO₂Me-4- methyl 3-(4,5-dihydro- CF₃Ph isoxazol-3-yl)Ph 2552 2-Me-4-SO₂Me- 2-SO₂Me-4- i-propyl 3-(4,5-dihydro- CF₃Ph isoxazol-3-yl)Ph 2553 2-Me-4-SO₂Me- 2-SO₂Me-4- cyclopropyl 3-(4,5-dihydro- CF₃Ph isoxazol-3-yl)Ph 2554 2-Me-4-SO₂Me- 2-SO₂Me-4- CF₃ 3-(4,5-dihydro- CF₃Ph isoxazol-3-yl)Ph 2555 4,4-dioxide-8- 1,2,4-oxadiazol-5- H Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2556 4,4-dioxide-8- 1,2,4-oxadiazol-5- methyl Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2557 4,4-dioxide-8- 1,2,4-oxadiazol-5- i-propyl Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2558 4,4-dioxide-8- 1,2,4-oxadiazol-5- cyclopropyl Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2559 4,4-dioxide-8- 1,2,4-oxadiazol-5- CF₃ Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2560 4,4-dioxide-8- 3-methyl-1,2,4- H Me-2,3-dihydro- oxadiazol-5-yl 1,4-benzoxathiin- 7-yl 2561 4,4-dioxide-8- 3-methyl-1,2,4- methyl Me-2,3-dihydro- oxadiazol-5-yl 1,4-benzoxathiin- 7-yl 2562 4,4-dioxide-8- 3-methyl-1,2,4- i-propyl Me-2,3-dihydro- oxadiazol-5-yl 1,4-benzoxathiin- 7-yl 2563 4,4-dioxide-8- 3-methyl-1,2,4- cyclopropyl Me-2,3-dihydro- oxadiazol-5-yl 1,4-benzoxathiin- 7-yl 2564 4,4-dioxide-8- 3-methyl-1,2,4- CF₃ Me-2,3-dihydro- oxadiazol-5-yl 1,4-benzoxathiin- 7-yl 2565 4,4-dioxide-8- 3-trifluoromethyl- H Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2566 4,4-dioxide-8- 3-trifluoromethyl- methyl Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2567 4,4-dioxide-8- 3-trifluoromethyl- i-propyl Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2568 4,4-dioxide-8- 3-trifluoromethyl- cyclopro Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2569 4,4-dioxide-8- 3-trifluoromethyl- CF₃ Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2570 4,4-dioxide-8- 1,2,4-oxadiazol-3- H Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2571 4,4-dioxide-8- 1,2,4-oxadiazol-3- methyl Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2572 4,4-dioxide-8- 1,2,4-oxadiazol-3- i-propyl Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2573 4,4-dioxide-8- 1,2,4-oxadiazol-3- cycloprop Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2574 4,4-dioxide-8- 1,2,4-oxadiazol-3- CF₃ Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2575 4,4-dioxide-8- 5-methyl-1,2,4- H Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2576 4,4-dioxide-8- 5-methyl-1,2,4- methyl Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2577 4,4-dioxide-8- 5-methyl-1,2,4- i-propyl Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2578 4,4-dioxide-8- 5-methyl-1,2,4- cycloprop Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2579 4,4-dioxide-8- 5-methyl-1,2,4- CF₃ Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2580 4,4-dioxide-8- 5-trifluoromethyl- H Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2581 4,4-dioxide-8- 5-trifluoromethyl- methyl Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2582 4,4-dioxide-8- 5-trifluoromethyl- i-propyl Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2583 4,4-dioxide-8- 5-trifluoromethyl- cycloprop Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2584 4,4-dioxide-8- 5-trifluoromethyl- CF₃ Me-2,3-dihydro- 1,2,4-oxadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2585 4,4-dioxide-8- 5-chloro-1,2,4- H Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2586 4,4-dioxide-8- 5-chloro-1,2,4- methyl Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2587 4,4-dioxide-8- 5-chloro-1,2,4- i-propyl Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2588 4,4-dioxide-8- 5-chloro-1,2,4- cycloprop Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2589 4,4-dioxide-8- 5-chloro-1,2,4- CF₃ Me-2,3-dihydro- oxadiazol-3-yl 1,4-benzoxathiin- 7-yl 2590 4,4-dioxide-8- 1,3,4-oxadiazol-2- H Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2591 4,4-dioxide-8- 1,3,4-oxadiazol-2- methyl Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2592 4,4-dioxide-8- 1,3,4-oxadiazol-2- i-propyl Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2593 4,4-dioxide-8- 1,3,4-oxadiazol-2- cycloprop Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2594 4,4-dioxide-8- 1,3,4-oxadiazol-2- CF₃ Me-2,3-dihydro- yl 1,4-benzoxathiin- 7-yl 2595 4,4-dioxide-8- 5-methylsulfonyl- H Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2596 4,4-dioxide-8- 5-methylsulfonyl- methyl Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2597 4,4-dioxide-8- 5-methylsulfonyl- i-propyl Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2598 4,4-dioxide-8- 5-methylsulfonyl- cyclopropyl Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2599 4,4-dioxide-8- 5-methylsulfonyl- CF₃ Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2600 4,4-dioxide-8- 5-methyl-1,3,4- H Me-2,3-dihydro- oxadiazol-2-yl 1,4-benzoxathiin- 7-yl 2601 4,4-dioxide-8- 5-methyl-1,3,4- methyl Me-2,3-dihydro- oxadiazol-2-yl 1,4-benzoxathiin- 7-yl 2602 4,4-dioxide-8- 5-methyl-1,3,4- i-propyl Me-2,3-dihydro- oxadiazol-2-yl 1,4-benzoxathiin- 7-yl 2603 4,4-dioxide-8- 5-methyl-1,3,4- cyclopropyl Me-2,3-dihydro- oxadiazol-2-yl 1,4-benzoxathiin- 7-yl 2604 4,4-dioxide-8- 5-methyl-1,3,4- CF₃ Me-2,3-dihydro- oxadiazol-2-yl 1,4-benzoxathiin- 7-yl 2605 4,4-dioxide-8- 5-trifluoromethyl- H Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2606 4,4-dioxide-8- 5-trifluoromethyl- methyl Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2607 4,4-dioxide-8- 5-trifluoromethyl- i-propyl Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2608 4,4-dioxide-8- 5-trifluoromethyl- cyclopropyl Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2609 4,4-dioxide-8- 5-trifluoromethyl- CF₃ Me-2,3-dihydro- 1,3,4-oxadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2610 4,4-dioxide-8- 1,2,3-triazol-4-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2611 4,4-dioxide-8- 1,2,3-triazol-4-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2612 4,4-dioxide-8- 1,2,3-triazol-4-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2613 4,4-dioxide-8- 1,2,3-triazol-4-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2614 4,4-dioxide-8- 1,2,3-triazol-4-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2615 4,4-dioxide-8- 1-methyl-1,2,3- H Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2616 4,4-dioxide-8- 1-methyl-1,2,3- methyl Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2617 4,4-dioxide-8- 1-methyl-1,2,3- i-propyl Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2618 4,4-dioxide-8- 1-methyl-1,2,3- cyclopropyl Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2619 4,4-dioxide-8- 1-methyl-1,2,3- CF₃ Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2620 4,4-dioxide-8- 2-methyl-1,2,3- H Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2621 4,4-dioxide-8- 2-methyl-1,2,3- methyl Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2622 4,4-dioxide-8- 2-methyl-1,2,3- i-propyl Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2623 4,4-dioxide-8- 2-methyl-1,2,3- cyclopropyl Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2624 4,4-dioxide-8- 2-methyl-1,2,3- CF₃ Me-2,3-dihydro- triazol-4-yl 1,4-benzoxathiin- 7-yl 2625 4,4-dioxide-8- 1,2,3-triazol-1-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2626 4,4-dioxide-8- 1,2,3-triazol-1-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2627 4,4-dioxide-8- 1,2,3-triazol-1-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2628 4,4-dioxide-8- 1,2,3-triazol-1-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2629 4,4-dioxide-8- 1,2,3-triazol-1-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2630 4,4-dioxide-8- 1,2,3-triazol-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2631 4,4-dioxide-8- 1,2,3-triazol-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2632 4,4-dioxide-8- 1,2,3-triazol-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2633 4,4-dioxide-8- 1,2,3-triazol-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2634 4,4-dioxide-8- 1,2,3-triazol-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2635 4,4-dioxide-8- 1,2,4-triazol-1-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2636 4,4-dioxide-8- 1,2,4-triazol-1-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2637 4,4-dioxide-8- 1,2,4-triazol-1-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2638 4,4-dioxide-8- 1,2,4-triazol-1-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2639 4,4-dioxide-8- 1,2,4-triazol-1-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2640 4,4-dioxide-8- imidazol-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2641 4,4-dioxide-8- imidazol-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2642 4,4-dioxide-8- imidazol-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2643 4,4-dioxide-8- imidazol-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2644 4,4-dioxide-8- imidazol-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2645 4,4-dioxide-8- imidazol-1-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2646 4,4-dioxide-8- imidazol-1-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2647 4,4-dioxide-8- imidazol-1-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2648 4,4-dioxide-8- imidazol-1-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2649 4,4-dioxide-8- imidazol-1-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2650 4,4-dioxide-8- imidazol-4-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2651 4,4-dioxide-8- imidazol-4-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2652 4,4-dioxide-8- imidazol-4-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2653 4,4-dioxide-8- imidazol-4-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2654 4,4-dioxide-8- imidazol-4-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2655 4,4-dioxide-8- thiazol-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2656 4,4-dioxide-8- thiazol-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2657 4,4-dioxide-8- thiazol-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2658 4,4-dioxide-8- thiazol-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2659 4,4-dioxide-8- thiazol-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2660 4,4-dioxide-8- 4-methylthiazol- H Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2661 4,4-dioxide-8- 4-methylthiazol- methyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2662 4,4-dioxide-8- 4-methylthiazol- i-propyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2663 4,4-dioxide-8- 4-methylthiazol- cyclopropyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2664 4,4-dioxide-8- 4-methylthiazol- CF₃ Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2665 4,4-dioxide-8- oxazol-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2666 4,4-dioxide-8- oxazol-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2667 4,4-dioxide-8- oxazol-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2668 4,4-dioxide-8- oxazol-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2669 4,4-dioxide-8- oxazol-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2670 4,4-dioxide-8- 4,5-dimethyl- H Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2671 4,4-dioxide-8- 4,5-dimethyl- methyl Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2672 4,4-dioxide-8- 4,5-dimethyl- i-propyl Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2673 4,4-dioxide-8- 4,5-dimethyl- cyclopropyl Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2674 4,4-dioxide-8- 4,5-dimethyl- CF₃ Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2675 4,4-dioxide-8- 2-oxazolin-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2676 4,4-dioxide-8- 2-oxazolin-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2677 4,4-dioxide-8- 2-oxazolin-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2678 4,4-dioxide-8- 2-oxazolin-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2679 4,4-dioxide-8- 2-oxazolin-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2680 4,4-dioxide-8- 4,4-dimethyl-2- H Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2681 4,4-dioxide-8- 4,4-dimethyl-2- methyl Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2682 4,4-dioxide-8- 4,4-dimethyl-2- i-propyl Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2683 4,4-dioxide-8- 4,4-dimethyl-2- cyclopropyl Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2684 4,4-dioxide-8- 4,4-dimethyl-2- CF₃ Me-2,3-dihydro- oxazol-2-yl 1,4-benzoxathiin- 7-yl 2685 4,4-dioxide-8- 1,2,4-thiadiazol- H Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2686 4,4-dioxide-8- 1,2,4-thiadiazol- methyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2687 4,4-dioxide-8- 1,2,4-thiadiazol- i-propyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2688 4,4-dioxide-8- 1,2,4-thiadiazol- cyclopropyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2689 4,4-dioxide-8- 1,2,4-thiadiazol- CF₃ Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2690 4,4-dioxide-8- 3-methyl-1,2,4- H Me-2,3-dihydro- thiadiazol-5-yl 1,4-benzoxathiin- 7-yl 2691 4,4-dioxide-8- 3-methyl-1,2,4- methyl Me-2,3-dihydro- thiadiazol-5-yl 1,4-benzoxathiin- 7-yl 2692 4,4-dioxide-8- 3-methyl-1,2,4- i-propyl Me-2,3-dihydro- thiadiazol-5-yl 1,4-benzoxathiin- 7-yl 2693 4,4-dioxide-8- 3-methyl-1,2,4- cyclopropyl Me-2,3-dihydro- thiadiazol-5-yl 1,4-benzoxathiin- 7-yl 2694 4,4-dioxide-8- 3-methyl-1,2,4- CF₃ Me-2,3-dihydro- thiadiazol-5-yl 1,4-benzoxathiin- 7-yl 2695 4,4-dioxide-8- 3-trifluoromethyl- H Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2696 4,4-dioxide-8- 3-trifluoromethyl- methyl Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2697 4,4-dioxide-8- 3-trifluoromethyl- i-propyl Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2698 4,4-dioxide-8- 3-trifluoromethyl- cyclopropyl Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2699 4,4-dioxide-8- 3-trifluoromethyl- CF₃ Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 5-yl 7-yl 2700 4,4-dioxide-8- 1,2,4-thiadiazol- H Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2701 4,4-dioxide-8- 1,2,4-thiadiazol- methyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2702 4,4-dioxide-8- 1,2,4-thiadiazol- i-propyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2703 4,4-dioxide-8- 1,2,4-thiadiazol- cyclopropyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2704 4,4-dioxide-8- 1,2,4-thiadiazol- CF₃ Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2705 4,4-dioxide-8- 5-methyl-1,2,4- H Me-2,3-dihydro- thiadiazol-3-yl 1,4-benzoxathiin- 7-yl 2706 4,4-dioxide-8- 5-methyl-1,2,4- methyl Me-2,3-dihydro- thiadiazol-3-yl 1,4-benzoxathiin- 7-yl 2707 4,4-dioxide-8- 5-methyl-1,2,4- i-propyl Me-2,3-dihydro- thiadiazol-3-yl 1,4-benzoxathiin- 7-yl 2708 4,4-dioxide-8- 5-methyl-1,2,4- cyclopropyl Me-2,3-dihydro- thiadiazol-3-yl 1,4-benzoxathiin- 7-yl 2709 4,4-dioxide-8- 5-methyl-1,2,4- CF₃ Me-2,3-dihydro- thiadiazol-3-yl 1,4-benzoxathiin- 7-yl 2710 4,4-dioxide-8- 5-trifluoromethyl- H Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2711 4,4-dioxide-8- 5-trifluoromethyl- methyl Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2712 4,4-dioxide-8- 5-trifluoromethyl- i-propyl Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2713 4,4-dioxide-8- 5-trifluoromethyl- cyclopropyl Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2714 4,4-dioxide-8- 5-trifluoromethyl- CF₃ Me-2,3-dihydro- 1,2,4-thiadiazol- 1,4-benzoxathiin- 3-yl 7-yl 2715 4,4-dioxide-8- 1,3,4-thiadiazol- H Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2716 4,4-dioxide-8- 1,3,4-thiadiazol- methyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2717 4,4-dioxide-8- 1,3,4-thiadiazol- i-propyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2718 4,4-dioxide-8- 1,3,4-thiadiazol- cyclopropyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2719 4,4-dioxide-8- 1,3,4-thiadiazol- CF₃ Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2720 4,4-dioxide-8- 5-methylsulfonyl- H Me-2,3-dihydro- 1,3,4-thiadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2721 4,4-dioxide-8- 5-methylsulfonyl- methyl Me-2,3-dihydro- 1,3,4-thiadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2722 4,4-dioxide-8- 5-methylsulfonyl- i-propyl Me-2,3-dihydro- 1,3,4-thiadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2723 4,4-dioxide-8- 5-methylsulfonyl- cyclopropyl Me-2,3-dihydro- 1,3,4-thiadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2724 4,4-dioxide-8- 5-methylsulfonyl- CF₃ Me-2,3-dihydro- 1,3,4-thiadiazol- 1,4-benzoxathiin- 2-yl 7-yl 2725 4,4-dioxide-8- 5-methyl-1,3,4- H Me-2,3-dihydro- thiadiazol-2-yl 1,4-benzoxathiin- 7-yl 2726 4,4-dioxide-8- 5-methyl-1,3,4- methyl Me-2,3-dihydro- thiadiazol-2-yl 1,4-benzoxathiin- 7-yl 2727 4,4-dioxide-8- 5-methyl-1,3,4- i-propyl Me-2,3-dihydro- thiadiazol-2-yl 1,4-benzoxathiin- 7-yl 2728 4,4-dioxide-8- 5-methyl-1,3,4- cyclopropyl Me-2,3-dihydro- thiadiazol-2-yl 1,4-benzoxathiin- 7-yl 2729 4,4-dioxide-8- 5-methyl-1,3,4- CF₃ Me-2,3-dihydro- thiadiazol-2-yl 1,4-benzoxathiin- 7-yl 2730 4,4-dioxide-8- benzoxazol-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2731 4,4-dioxide-8- benzoxazol-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2732 4,4-dioxide-8- benzoxazol-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2733 4,4-dioxide-8- benzoxazol-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2734 4,4-dioxide-8- benzoxazol-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2735 4,4-dioxide-8- 6-methyl- H Me-2,3-dihydro- benzoxazol-2-yl 1,4-benzoxathiin- 7-yl 2736 4,4-dioxide-8- 6-methyl- methyl Me-2,3-dihydro- benzoxazol-2-yl 1,4-benzoxathiin- 7-yl 2737 4,4-dioxide-8- 6-methyl- i-propyl Me-2,3-dihydro- benzoxazol-2-yl 1,4-benzoxathiin- 7-yl 2738 4,4-dioxide-8- 6-methyl- cyclopropyl Me-2,3-dihydro- benzoxazol-2-yl 1,4-benzoxathiin- 7-yl 2739 4,4-dioxide-8- 6-methyl- CF₃ Me-2,3-dihydro- benzoxazol-2-yl 1,4-benzoxathiin- 7-yl 2740 4,4-dioxide-8- benzothiazol-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2741 4,4-dioxide-8- benzothiazol-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2742 4,4-dioxide-8- benzothiazol-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2743 4,4-dioxide-8- benzothiazol-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2744 4,4-dioxide-8- benzothiazol-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2745 4,4-dioxide-8- pyrazol-1-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2746 4,4-dioxide-8- pyrazol-1-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2747 4,4-dioxide-8- pyrazol-1-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2748 4,4-dioxide-8- pyrazol-1-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2749 4,4-dioxide-8- pyrazol-1-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2750 4,4-dioxide-8- pyrazol-3-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2751 4,4-dioxide-8- pyrazol-3-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2752 4,4-dioxide-8- pyrazol-3-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2753 4,4-dioxide-8- pyrazol-3-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2754 4,4-dioxide-8- pyrazol-3-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2755 4,4-dioxide-8- 1-methylpyrazol- H Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2756 4,4-dioxide-8- 1-methylpyrazol- methyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2757 4,4-dioxide-8- 1-methylpyrazol- i-propyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2758 4,4-dioxide-8- 1-methylpyrazol- cyclopropyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2759 4,4-dioxide-8- 1-methylpyrazol- CF₃ Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2760 4,4-dioxide-8- tetrazol-1-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2761 4,4-dioxide-8- tetrazol-1-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2762 4,4-dioxide-8- tetrazol-1-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 4,4-dioxide-8- 2763 Me-2,3-dihydro- tetrazol-1-yl cyclopropyl 1,4-benzoxathiin- 7-yl 4,4-dioxide-8- 2764 Me-2,3-dihydro- tetrazol-1-yl CF₃ 1,4-benzoxathiin- 7-yl 2765 4,4-dioxide-8- 5-methyltetrazol- H Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2766 4,4-dioxide-8- 5-methyltetrazol- methyl Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2767 4,4-dioxide-8- 5-methyltetrazol- i-propyl Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2768 4,4-dioxide-8- 5-methyltetrazol- cyclopropyl Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2769 4,4-dioxide-8- 5-methyltetrazol- CF₃ Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2770 4,4-dioxide-8- tetrazol-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2771 4,4-dioxide-8- tetrazol-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2772 4,4-dioxide-8- tetrazol-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2773 4,4-dioxide-8- tetrazol-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2774 4,4-dioxide-8- tetrazol-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2775 4,4-dioxide-8- 5-methyltetrazol- H Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2776 4,4-dioxide-8- 5-methyltetrazol- methyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2777 4,4-dioxide-8- 5-methyltetrazol- i-propyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2778 4,4-dioxide-8- 5-methyltetrazol- cyclopropyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2779 4,4-dioxide-8- 5-methyltetrazol- CF₃ Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2780 4,4-dioxide-8- 1-methyltetrazol- H Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2781 4,4-dioxide-8- 1-methyltetrazol- methyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2782 4,4-dioxide-8- 1-methyltetrazol- i-propyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2783 4,4-dioxide-8- 1-methyltetrazol- cyclopropyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2784 4,4-dioxide-8- 1-methyltetrazol- CF₃ Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2785 4,4-dioxide-8- 2-methyltetrazol- H Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2786 4,4-dioxide-8- 2-methyltetrazol- methyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2787 4,4-dioxide-8- 2-methyltetrazol- i-propyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2788 4,4-dioxide-8- 2-methyltetrazol- cyclopropyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2789 4,4-dioxide-8- 2-methyltetrazol- CF₃ Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2790 4,4-dioxide-8- pyridin-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2791 4,4-dioxide-8- pyridin-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2792 4,4-dioxide-8- pyridin-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2793 4,4-dioxide-8- pyridin-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2794 4,4-dioxide-8- pyridin-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2795 4,4-dioxide-8- pyridin-4-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2796 4,4-dioxide-8- pyridin-4-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2797 4,4-dioxide-8- pyridin-4-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2798 4,4-dioxide-8- pyridin-4-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2799 4,4-dioxide-8- pyridin-4-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2800 4,4-dioxide-8- pyridin-3-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2801 4,4-dioxide-8- pyridin-3-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2802 4,4-dioxide-8- pyridin-3-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2803 4,4-dioxide-8- pyridin-3-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2804 4,4-dioxide-8- pyridin-3-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2805 4,4-dioxide-8- 3-nitropyridin- H Me-2,3-dihydro- 4-yl 1,4-benzoxathiin- 7-yl 2806 4,4-dioxide-8- 3-nitropyridin- methyl Me-2,3-dihydro- 4-yl 1,4-benzoxathiin- 7-yl 2807 4,4-dioxide-8- 3-nitropyridin- i-propyl Me-2,3-dihydro- 4-yl 1,4-benzoxathiin- 7-yl 2808 4,4-dioxide-8- 3-nitropyridin- cyclopropyl Me-2,3-dihydro- 4-yl 1,4-benzoxathiin- 7-yl 2809 4,4-dioxide-8- 3-nitropyridin- CF₃ Me-2,3-dihydro- 4-yl 1,4-benzoxathiin- 7-yl 2810 4,4-dioxide-8- 5-cyanopyridin- H Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2811 4,4-dioxide-8- 5-cyanopyridin- methyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2812 4,4-dioxide-8- 5-cyanopyridin- i-propyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2813 4,4-dioxide-8- 5-cyanopyridin- cyclopropyl Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2814 4,4-dioxide-8- 5-cyanopyridin- CF₃ Me-2,3-dihydro- 2-yl 1,4-benzoxathiin- 7-yl 2815 4,4-dioxide-8- 5-trifluoro- H Me-2,3-dihydro- methylpyridin- 1,4-benzoxathiin- 2-yl 7-yl 2816 4,4-dioxide-8- 5-trifluoro- methyl Me-2,3-dihydro- methylpyridin- 1,4-benzoxathiin- 2-yl 7-yl 2817 4,4-dioxide-8- 5-trifluoro- i-propyl Me-2,3-dihydro- methylpyridin- 1,4-benzoxathiin- 2-yl 7-yl 2818 4,4-dioxide-8- 5-trifluoro- cyclopropyl Me-2,3-dihydro- methylpyridin- 1,4-benzoxathiin- 2-yl 7-yl 2819 4,4-dioxide-8- 5-trifluoro- CF₃ Me-2,3-dihydro- methylpyridin- 1,4-benzoxathiin- 2-yl 7-yl 2820 4,4-dioxide-8- pyrimidin-2-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2821 4,4-dioxide-8- pyrimidin-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2822 4,4-dioxide-8- pyrimidin-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2823 4,4-dioxide-8- pyrimidin-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2824 4,4-dioxide-8- pyrimidin-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2825 4,4-dioxide-8- pyrimidin-4-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2826 4,4-dioxide-8- pyrimidin-4-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2827 4,4-dioxide-8- pyrimidin-4-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2828 4,4-dioxide-8- pyrimidin-4-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2829 4,4-dioxide-8- pyrimidin-4-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2830 4,4-dioxide-8- 6-chloro- methyl Me-2,3-dihydro- pyrimidin-4-yl 1,4-benzoxathiin- 7-yl 2831 4,4-dioxide-8- 6-chloro- i-propyl Me-2,3-dihydro- pyrimidin-4-yl 1,4-benzoxathiin- 7-yl 2832 4,4-dioxide-8- 6-chloro- cyclopropyl Me-2,3-dihydro- pyrimidin-4-yl 1,4-benzoxathiin- 7-yl 2833 4,4-dioxide-8- 6-chloro- CF₃ Me-2,3-dihydro- pyrimidin-4-yl 1,4-benzoxathiin- 7-yl 2834 4,4-dioxide-8- pyridazin-3-yl H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2835 4,4-dioxide-8- pyridazin-3-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2836 4,4-dioxide-8- pyridazin-3-yl i-propy Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2837 4,4-dioxide-8- pyridazin-3-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2838 4,4-dioxide-8- pyridazin-3-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2839 4,4-dioxide-8- 6-chloro- methyl Me-2,3-dihydro- pyridazin-3-yl 1,4-benzoxathiin- 7-yl 2840 4,4-dioxide-8- 6-chloro- i-propyl Me-2,3-dihydro- pyridazin-3-yl 1,4-benzoxathiin- 7-yl 2841 4,4-dioxide-8- 6-chloro- cyclopropyl Me-2,3-dihydro- pyridazin-3-yl 1,4-benzoxathiin- 7-yl 2842 4,4-dioxide-8- 6-chloro- CF₃ Me-2,3-dihydro- pyridazin-3-yl 1,4-benzoxathiin- 7-yl 2843 4,4-dioxide-8- pyrazin-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2844 4,4-dioxide-8- pyrazin-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2845 4,4-dioxide-8- pyrazin-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2846 4,4-dioxide-8- pyrazin-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2847 4,4-dioxide-8- triazin-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2848 4,4-dioxide-8- triazin-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2849 4,4-dioxide-8- triazin-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2850 4,4-dioxide-8- triazin-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2851 4,4-dioxide-8- quinolin-2-yl methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2852 4,4-dioxide-8- quinolin-2-yl i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2853 4,4-dioxide-8- quinolin-2-yl cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2854 4,4-dioxide-8- quinolin-2-yl CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2855 4,4-dioxide-8- 4,4,6-trimethyl- H Me-2,3-dihydro- 5,6-dihydro-1, 1,4-benzoxathiin- 3(4H)-oxazin-2-yl 7-yl 2856 4,4-dioxide-8- 4,4,6-trimethyl- methyl Me-2,3-dihydro- 5,6-dihydro-1, 1,4-benzoxathiin- 3(4H)-oxazin-2-yl 7-yl 2857 4,4-dioxide-8- 4,4,6-trimethyl- i-propyl Me-2,3-dihydro- 5,6-dihydro-1, 1,4-benzoxathiin- 3(4H)-oxazin-2-yl 7-yl 2858 4,4-dioxide-8- 4,4,6-trimethyl- cyclopropyl Me-2,3-dihydro- 5,6-dihydro-1, 1,4-benzoxathiin- 3(4H)-oxazin-2-yl 7-yl 2859 4,4-dioxide-8- 4,4,6-trimethyl- CF₃ Me-2,3-dihydro- 5,6-dihydro-1, 1,4-benzoxathiin- 3(4H)-oxazin-2-yl 7-yl 2860 4,4-dioxide-8- 2-oxazolidinon- H Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2861 4,4-dioxide-8- 2-oxazolidinon- methyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2862 4,4-dioxide-8- 2-oxazolidinon- i-propyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2863 4,4-dioxide-8- 2-oxazolidinon- cyclopropyl Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2864 4,4-dioxide-8- 2-oxazolidinon- CF₃ Me-2,3-dihydro- 3-yl 1,4-benzoxathiin- 7-yl 2865 4,4-dioxide-8- 2-pyrrolidinon- methyl Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2866 4,4-dioxide-8- 2-pyrrolidinon- i-propyl Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2867 4,4-dioxide-8- 2-pyrrolidinon- cyclopropyl Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2868 4,4-dioxide-8- 2-pyrrolidinon- CF₃ Me-2,3-dihydro- 1-yl 1,4-benzoxathiin- 7-yl 2869 4,4-dioxide-8- 3-methylisoxazol- methyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2870 4,4-dioxide-8- 3-methylisoxazol- i-propyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2871 4,4-dioxide-8- 3-methylisoxazol- cyclopropyl Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2872 4,4-dioxide-8- 3-methylisoxazol- CF₃ Me-2,3-dihydro- 5-yl 1,4-benzoxathiin- 7-yl 2873 4,4-dioxide-8- 2-NO₂-4- H Me-2,3-dihydro- SO₂MePh 1,4-benzoxathiin- 7-yl 2874 4,4-dioxide-8- 2-NO₂-4- methyl Me-2,3-dihydro- SO₂MePh 1,4-benzoxathiin- 7-yl 2875 4,4-dioxide-8- 2-NO₂-4- i-propyl Me-2,3-dihydro- SO₂MePh 1,4-benzoxathiin- 7-yl 2876 4,4-dioxide-8- 2-NO₂-4- cyclopropyl Me-2,3-dihydro- SO₂MePh 1,4-benzoxathiin- 7-yl 2877 4,4-dioxide-8- 2-NO₂-4- CF₃ Me-2,3-dihydro- SO₂MePh 1,4-benzoxathiin- 7-yl 2878 4,4-dioxide-8- 2-Cl-4-SO₂MePh H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2879 4,4-dioxide-8- 2-Cl-4-SO₂MePh methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2880 4,4-dioxide-8- 2-Cl-4-SO₂MePh i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2881 4,4-dioxide-8- 2-Cl-4-SO₂MePh cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2882 4,4-dioxide-8- 2-Cl-4-SO₂MePh CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2883 4,4-dioxide-8- 2-NO₂-4-CF₃Ph H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2884 4,4-dioxide-8- 2-NO₂-4-CF₃Ph methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2885 4,4-dioxide-8- 2-NO₂-4-CF₃Ph i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2886 4,4-dioxide-8- 2-NO₂-4-CF₃Ph cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2887 4,4-dioxide-8- 2-NO₂-4-CF₃Ph CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2888 4,4-dioxide-8- 2-NO₂-4-ClPh H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2889 4,4-dioxide-8- 2-NO₂-4-ClPh methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2890 4,4-dioxide-8- 2-NO₂-4-ClPh i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2891 4,4-dioxide-8- 2-NO₂-4-ClPh cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2892 4,4-dioxide-8- 2-NO₂-4-ClPh CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2893 4,4-dioxide-8- 2-Cl-4-NO₂Ph H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2894 4,4-dioxide-8- 2-Cl-4-NO₂Ph methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2895 4,4-dioxide-8- 2-Cl-4-NO₂Ph i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2896 4,4-dioxide-8- 2-Cl-4-NO₂Ph cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2897 4,4-dioxide-8- 2-Cl-4-NO₂Ph CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2898 4,4-dioxide-8- 2,4-(NO₂)₂Ph H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2899 4,4-dioxide-8- 2,4-(NO₂)₂Ph methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2900 4,4-dioxide-8- 2,4-(NO₂)₂Ph i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2901 4,4-dioxide-8- 2,4-(NO₂)₂Ph cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2902 4,4-dioxide-8- 2,4-(NO₂)₂Ph CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2903 4,4-dioxide-8- 4-F-3-NO₂Ph H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2904 4,4-dioxide-8- 4-F-3-NO₂Ph methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2905 4,4-dioxide-8- 4-F-3-NO₂Ph i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2906 4,4-dioxide-8- 4-F-3-NO₂Ph cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2907 4,4-dioxide-8- 4-F-3-NO₂Ph CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2908 4,4-dioxide-8- 3,5-(CF₃)₂Ph H Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2909 4,4-dioxide-8- 3,5-(CF₃)₂Ph methyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2910 4,4-dioxide-8- 3,5-(CF₃)₂Ph i-propyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2911 4,4-dioxide-8- 3,5-(CF₃)₂Ph cyclopropyl Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2912 4,4-dioxide-8- 3,5-(CF₃)₂Ph CF₃ Me-2,3-dihydro- 1,4-benzoxathiin- 7-yl 2913 4,4-dioxide-8- 2-SO₂Me-4- H Me-2,3-dihydro- CF₃Ph 1,4-benzoxathiin- 7-yl 2914 4,4-dioxide-8- 2-SO₂Me-4- methyl Me-2,3-dihydro- CF₃Ph 1,4-benzoxathiin- 7-yl 2915 4,4-dioxide-8- 2-SO₂Me-4- i-propyl Me-2,3-dihydro- CF₃Ph 1,4-benzoxathiin- 7-yl 2916 4,4-dioxide-8- 2-SO₂Me-4- cyclopropyl Me-2,3-dihydro- CF₃Ph 1,4-benzoxathiin- 7-yl 2917 4,4-dioxide-8- 2-SO₂Me-4- CF₃ Me-2,3-dihydro- CF₃Ph 1,4-benzoxathiin- 7-yl 2918 2-Cl-4-SO₂MePh 2-trifluoro- cyclopropyl 185 methyl-1,3,4- thiadiazol-5-yl 2919 2-Cl-4-SO₂MePh 1,1-dioxido-3- cyclopropyl oxo-1,2- benzisothiazol- 2(3H)-yl 2920 4-Cl-Ph 2-t-butyl-1,3,4- CF₃ 166 oxadiazol-5-yl 2921 2-Me-6- 2-methyltetrazol- cyclopropyl CF₃pyridin-3-yl 5-yl 2922 2-[(2- 2-methyltetrazol- cyclopropyl oil methoxyethoxy) 5-yl methyl]- 6-CF₃ pyridin-3-yl 2923 2-Cl-4-SO₂MePh 2,5- cyclopropyl dioxopyrrolidin- 1-yl 2924 2-Cl-4-SO₂MePh 2-oxopyridin- cyclopropyl 1(2H)-yl 2925 2-Cl-4-SO₂MePh 2-oxoquinolin- cyclopropyl 1(2H)-yl 2926 2-Cl-4-SO₂MePh 1,2-benzisoxazol- cyclopropyl 3-yl 2927 2-Cl-4-SO₂MePh 2-oxo-1,3- cyclopropyl benzoxazol- 3(2H)-yl 2928 2-Cl-4-SO₂MePh 3-oxo-2,3- cyclopropyl dihydro-4H-1,4- benzoxazin-4-yl 2929 2-Cl-4-SO₂MePh 2-oxopyrimidin- cyclopropyl 1(2H)-yl 2930 2-Cl-4-SO₂MePh 1H-1,2,3- cyclopropyl benzotriazol-1-yl 2931 2-NO₂-4- 2,5- cyclopropyl SO₂MePH dioxopyrrolidin- 1-yl 2932 2-NO₂-4- 2-oxopyridin- cyclopropyl SO₂MePH 1(2H)-yl 2933 2-NO₂-4- 2-oxoquinolin- cyclopropyl SO₂MePH 1(2H)-yl 2934 2-NO₂-4- 1,2,- cyclopropyl SO₂MePH benzisoxazol-3-yl 2935 2-NO₂-4- 2-oxo-1,3- cyclopropyl SO₂MePH benzoxazol- 3(2H)-yl 2936 2-NO₂-4- 3-oxo-2,3- cyclopropyl SO₂MePH dihydro-4H-1,4- benzoxazin-4-yl 2937 2-NO₂-4- 2-oxopyrimidin- cyclopropyl SO₂MePH 1(2H)-yl 2938 2-NO₂-4- 1H-1,2,3- cyclopropyl SO₂MePH benzotriazol-1-yl

EXAMPLE 31 Determination of the Herbicidal Activity and Phyto-Toxicity in Pre-Emergence

The herbicidal activity of the compounds of the invention in pre-emergence was evaluated according to the following operative procedures.

The plant species of interest (weeds or crops) were sown in pots with an upper diameter of 10 cm, a height of 10 cm and containing sandy soil. 10 pots were used for each plant species.

Water was added to each pot in such a quantity as to germinate the seeds. The pots were divided into two groups, each containing 5 pots for each weed or crop.

After one day from the sowing, the first set of pots was treated with a hydro-acetonic dispersion containing acetone at 10% in volume, the product under evaluation at the desired concentration and Tween 20 at 0.5%.

The second set was treated with a hydro-acetonic solution only, containing acetone at 10% in volume and Tween 20 at 0.5%, and was used as comparison (blank).

All pots were kept under observation in a conditioned environment under the following conditions:

-   temperature: 24° C.; -   relative humidity: 60%; -   photoperiod: 16 hours; -   light intensity: 10000 lux.

The pots were uniformly watered in order to ensure a sufficient humidity degree for a good development of the plants.

Fifteen days after the treatment, the herbicidal activity was evaluated on the basis of the following values, which refer to the damage percentage tested on the treated plants, with respect to the non-treated plants (blank): 0 = 0-10% damage; 1 = 11-30% damage; 2 = 31-50% damage; 3 = 51-70% damage; 4 = 71-90% damage; 5 = 91% damage - death of the plant.

Table 3 shows the results obtained by treating the plant species listed below with compounds 6, 7 and 11 with a dosage of 500 g/ha:

Abutilon theofrasti (AT); Amaranthus retroflexus (AR); Chenopodium album (CA); Galium aparine (GA); Ipomea purpurea (IP); Portulaca oleracea (PO); Solanum nigrum (SN); Stellaria media (SM). TABLE 3 Pre-emergence herbicidal activity at rate of 500 g/ha Plant species: AT AR CA GA IP PO SN SM Compound N^(o) 6: 5 5 5 5 5 5 5 5 Compound N^(o) 7: 5 5 5 — — 5 5 5 Compound N^(o) 11: 5 — 5 — 5 5 — —

EXAMPLE 32 Determination of the Herbicidal Activity and Phyto-Toxicity in Post-emergence

The herbicidal activity of the compounds of the invention in post-emergence was evaluated according to the following operative procedures.

The plant species of interest (weeds or crops) were sown in pots with an upper diameter of 10 cm, a height of 10 cm and containing sandy soil. 10 pots were used for each plant species.

Water was added to each pot in such a quantity as to germinate the seeds. The pots were divided into two groups, each containing 5 pots for each weed or crop.

Fifteen days after sowing (ten, in the case of wheat), when the weeds and crops, according to the species, were 10-15 cm high, the first set of pots was treated with a hydro-acetonic dispersion containing acetone at 10% in volume, the product under evaluation at the desired concentration and Tween 20 at 0.5%.

The second set was treated with a hydro-acetonic solution only, containing acetone at 10% in volume and Tween 20 at 0.5%, and was used as comparison (blank).

All pots were kept under observation in a conditioned environment under the following conditions:

-   temperature: 24° C.; -   relative humidity: 60%; -   photo-period: 16 hours; -   light intensity: 10000 lux.

The pots were uniformly watered every other day so as to ensure a humidity degree sufficient for a good development of the plants.

The herbicidal activity was evaluated fifteen days after the treatment, on the basis of the following values which refer to the percentage of damage tested on the treated plants with respect to the non-treated plants (blank): 0 = 0-10% damage; 1 = 11-30% damage; 2 = 31-50% damage; 3 = 51-70% damage; 4 = 71-90% damage; 5 = 91% damage - death of the plant.

Table 4 shows the results obtained by treating the plant species listed below with compounds 6 and 11 with a dosage of 500 g/ha:

Abutilon theofrasti (AT); Chenopodium album (CA); Galium aparine (GA); Portulaca oleracea (PO); Solanum nigrum (SN); Stellaria media (SM). TABLE 4 Post-emergence herbicidal activity at rate of 500 g/ha Plant species: AT CA GA PO SN SM Compound N^(o) 6: 5 5 5 5 5 5 Compound N^(o) 11: 5 5 — — 5 — 

1. Derivatives of 1,3-diones having general formula (I):

wherein: A represents: an aryl group optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl optionally substituted with a group selected from C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈ alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀ alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂ dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂, -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄, —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆, -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; or it represents a heterocyclic group selected from pyridyl, pyrimidyl, quinolinyl, pyrazolyl, thiazolyl, oxazolyl, thienyl, furyl, benzothienyl, dihydrobenzothienyl, benzofuranyl, dihydrobenzofuranyl, benzoxazolyl, benzoxazolonyl, benzothiazolyl, benzothiazolonyl, benzoimidazolyl, benzoimidazolonyl, benzotriazolyl, chromanonyl, chromanyl, thiochromanonyl, thiochromanyl, 3a,4-dihydro-3H-indeno[1,2-c]isoxazolyl, 3a,4-dihydro-3H-chromeno[4, 3-c]isoxazolyl, 5,5-dioxide-3a,4-dihydro-3H-thiochromeno[4,3-c]isoxazolyl, 2,3,3a,4-tetrahydrochromeno[4,3-c]pyrazolyl, 6,6-dioxide-2,3-dihydro-5H-[1,4]dithiino[2,3-c]thiochromenyl, 5,5-dioxide-2,3,3a,4-tetrahydrothiochromeno[4,3-c]pyrazolyl, 1′,1′-dioxide-2′,3′-dihydrospiro[1,3-dioxolano-2,4′-thiochromen]-yl, 1,1,4,4-tetraoxide-2,3-dihydro-1,4-benzodithiin-6-yl, 4,4-dioxide-2,3-dihydro-1,4-benzoxathiin-7-yl, 1,1-dioxide-3-oxo-2,3-dihydro-1,2-benzoisothiazol-5-yl, 4-(alkoxyimino)-1,1-dioxide-3,4-dihydro-2H-thiochromen-6-yl, 1,1-dioxide-4-oxo-3,4-dihydro-2H-thiochromen-6-yl, 2,3-dihydro-1,4-benzoxathiin-7-yl, with said groups optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkyl sulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl optionally substituted with a group selected from C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈ alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₃₀ alkoxyalkynyloxyl, C₆-C₁₂ cycloalkyl ideneiminooxyalkyl, C₆-C₁₂ dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂, -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄, —(CR₂₆R₂₇)_(p)Z(CR₂₉R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆, -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇), (CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; B represents a D-(R_(x))_(n) group; R represents a hydrogen atom, a linear or branched C₁-C₆ alkyl group, a linear or branched C₁-C₆ haloalkyl group, a C₃-C₆ cycloalkyl or C₄-C₁₂ cyclo-alkylalkyl group optionally substituted with halogen atoms or C₁-C₆ alkyl or C₁-C₆ thioalkyl or C₁-C₆ alkoxyl or C₂-C₆ alkoxycarbonyl groups, C₂-C₆ alkenyl groups, C₂-C₆ alkynyl groups, the latter two groups, in turn, optionally substituted with halogen atoms, a C₅-C₆ cycloalkenyl group optionally substituted with halogen atoms or C₁-C₆ alkyl groups, an aryl or arylalkyl group optionally substituted; R₁ and R₁₉ represent a C₁-C₆ alkyl group or a C₁-C₆ haloalkyl group, a C₃-C₆ cycloalkyl group, an aryl group optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₃-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl; m is equal to 0, 1 or 2; t is equal to 1 or 2; R₂, R₃, R₆, R₇, R₈, R₉, R₁₀, R₁₁, R₁₇ and R₁₈, the same or different, represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn optionally substituted with halogen atoms, a C₁-C₆ alkoxyl group, a C₃-C₆ cycloalkyl group, an arylalkyl group or an aryl group, said arylalkyl and aryl groups also optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl, or they jointly represent a C₂-C₅ alkylene group; R₄, R₅ and R₄₂ represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn optionally substituted with halogen atoms, a C₃-C₆ alkenyl group in turn optionally substituted with halogen atoms, a Q₇ group, an arylalkyl group optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl; R₁₂, R₁₄ and R₁₆ represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn optionally substituted with halogen atoms, a C₃-C₆ cycloalkyl group, a C₁-C₆ alkoxyl group, a C₁-C₆ haloalkoxyl group; R₁₃ and R₁₅ represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn optionally substituted with halogen atoms, a C₃-C₆ alkenyl group in turn optionally substituted with halogen atoms, a Q₇, NH₂, NHCN, NHNH₂, NHOH group, an arylalkyl group optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₃-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl; R₂₀, R₂₁, R₂₂, R₂₃, R₂₄, R₂₅, R₂₆, R₂₇, R₂₈, R₂₉, R₃₀, R₃₁, R₃₂, R₃₃, R₃₄, R₃₅, R₃₆, R₃₇, R₃₈, R₃₉, R₄₀ and R₄₁, the same or different, represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn optionally substituted with halogen atoms, a C₁-C₆ alkoxyl group, or the two groups attached to the same carbon atom can be joined to each other by C₂-C₅ alkylene groups, the alkylene groups can in turn be substituted with C₁-C₃ alkyl groups; Q, Q₁, Q₂, Q₃, Q₄, Q₅, Q₆ and Q₇ represent an aryl group, a C₃-C₆ cycloalkyl group, a C₅-C₆ cycloalkenyl group, a heterocyclic group selected from triazolyl, triazolonyl, pyrazolyl, imidazolyl, imidazolidinonyl, tetrazolyl, tetrazolonyl, isoxazolyl, furyl, thienyl, pyrrolyl, pyrrolidinyl, pyrrolidinonyl, pyridyl, pyrimidinyl, pyrimidinonyl, pyrazinyl, pyridazinyl, oxazolyl, thiazolyl, oxadiazolyl, thiadiazolyl, isothiazolyl, benzoxazolyl, benzothiazolyl, isoxazolinyl, 1,3-dioxanyl, 1,4-dioxanyl, 1,3-dioxolanyl, tetrahydropyranyl, oxethanyl, oxyranyl, thiazolidinyl, oxazolidinyl, piperidinyl, piperidinonyl, piperazinyl, morpholinyl, thiazinyl, tetrahydrofuranyl, dioxazolyl, tetrahydrofuroisoxazolyl, 2-oxa-3-azabicyclo[3.1.0]hex-3-enyl, said groups optionally substituted by one or more substituents selected from halogen, NO₂, OH, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl optionally substituted with a group selected from C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈ alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀ alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂ dialkylideneiminooxyalkyl, aryl optionally substituted, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; Z, Z₁, Z₂=O, S(O)_(r); Y═O, S; r is equal to 0, 1 or 2; p, q are equal to 1, 2, 3 or 4; v is equal to 0 or 1; Z₃=O, S or a direct bond; T represents a hydrogen atom, a Z₄R₄₂ group, a —NR₄₃R₄₄ group, an aryl group or a heterocyclic group selected from triazolyl, triazolonyl, pyrazolyl, imidazolyl, imidazolidinonyl, tetrazolyl, tetrazolonyl, pyrrolyl, pyrrolidinyl, pyrrolidinonyl, pyridyl, pyrimidinyl, piperidinyl, piperidinonyl, piperazinyl, morpholinyl, said groups optionally substituted by one or more substituents selected from halogen, NO₂, OH, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, C₃-C₆ cycloalkyl, C₅-C₆ cycloalkenyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₃-C₆ cyanoalkcyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, —S(O)_(m)R₁; Z₄=O, S or a direct bond; R₄₃ and R₄₄, the same or different, represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn optionally substituted with halogen atoms, a C₃-C₆ alkenyl group in turn optionally substituted with halogen atoms, a Q₇ group, an arylalkyl group optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl, or they jointly represent a C₂-C₅ alkylene chain; D represents: a heterocyclic group of the heteroaryl or heterocyclic type, in all the above cases the heterocycle can be mono or polycyclic and can be connected to the rest of the structure either through one of its carbon atoms or, when possible, through one of its nitrogen atoms; or it represents a mono or polycyclic aryl group, in this latter case, the group can also be partially saturated; R_(x) represents a substituent selected from hydrogen, halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl optionally substituted with a group selected from C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈ alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀ alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂ dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂, -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄, —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆, -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; if several R_(x) groups are present, these can be the same or different; n=1-9; excluding the following compounds having general formula (I) wherein A, B and R have the following meanings: A=4-chlorophenyl, B=1-methylimidazol-2-yl, R═H; A=4-nitrophenyl, B=1-(2-hydroxyethyl)-5-nitroimidazol-2-yl, R═H; A=phenyl, B=1H-benzimidazol-2-yl, R═C₂H₅; A=phenyl, B=4H-1-benzopyran-4-yl, R═CH₃; A=4-nitrophenyl, B=3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl, R═CH₃; A=phenyl, B=4-chloro-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl, R═CH₃; A=phenyl, B=2-acetyl-1,2,3,4-tetrahydroisoquinolin-1-yl, R═C₂H₅; A=2-hydroxy-4-methoxyphenyl, B=thiazol-4-yl, R═CH₃; A=phenyl, B=2,5-diphenyl-1,3-oxathiol-2-yl, R═CH₃; A=4-nitrophenyl, B=4,6-bis(dimethylamino)-1,3,5-triazin-2-yl, R═CH₃; A=phenyl, B=furan-2-yl, R═CH₃; A=phenyl, B=1,3-dithian-2-yl, R═CH₃; A=phenyl, B=4-chlorothien-2-yl, R═H; A=phenyl, B=5-bromothien-2-yl, R═H; A=phenyl, B=5-methylthien-2-yl, R═H; A=phenyl, B=6-phenylpyrazin-2-yl, R═CH₃; A=phenyl, B=3,4-dihydro-3-methyl-2-oxo-2H-1,3-benzo-oxazin-4-yl, R═CH₃; A=phenyl, B=benzothiazol-2-yl, R═CH₃; A=2-hydroxy-4-methoxyphenyl, B=2-phenylthiazol-4-yl, R═CH₃; A=phenyl, B=5-methylfuran-2-yl, R═CH₃; A=phenyl, B=3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl, R═CH₃; A=phenyl, B=tetrahydrofuran-2-yl, R═CH₃; A=phenyl, B=2,3-dihydro-3-hydroxy-2-oxo-1H-indol-3-yl, R═CH₃, A=phenyl, B=4-chloro-1-methyl-2,5-dioxo-2,5-dihydro-pyrrol-3-yl, R═CH₃; A=phenyl, B=22-trifluoroacetyl-1,2,3,4-tetrahydroiso-quinolin-1-yl, R═C₂H₅; A=phenyl, B=2-acetyl-1,2,3,4-tetrahydroisoquinolin-1-yl, R═CH₃; A=4-nitrophenyl, B=2-(4-nitrophenyl)-3,5,6-triphenyl-pyridin-4-yl, R═CH₃; A=phenyl, B=4,6-bis (dimethylamino)-1,3,5-triazin-2-yl, R═CH₃; A=phenyl, B=4-methoxy-5-tert-butoxycarbonyl-1H-pyrro-2-yl, R═CH₃; A=phenyl, B=1,3-dihydro-3-oxo-isobenzofuran-1-yl, R═CH₃; A=phenyl, B=(5-methoxycarbonylmethyl)thien-2-yl, R═H; A=phenyl, B=4-methylthien-2-yl, R═H; A=phenyl, B=1,4-dihydro-1-methyl-3-nitroquinolin-4-yl, R═H; A=phenyl, B=thien-2-yl, R═H; A=phenyl, B=6-methylbenzothiazol-2-yl, R═CH₃; A=2-methoxycarbonylphenyl, B=phenyl, R═CH₃; A=2-benzyloxy-4-methoxyphenyl, B=2,3,4-trimethoxyphenyl, R═H; A=4,5-dimethoxy-2-nitrophenyl, B=3,4-dimethoxyphenyl, R═H; A=2-nitrophenyl, B=phenyl, R═H; A=2,4,5-trimethoxyphenyl, B=4-methoxyphenyl, R═H; A=4-bromophenyl, B=phenyl, R═H; A=4-bromophenyl, B=2,4-dinitrophenyl, R═CH₃; A=4-chlorophenyl, B=phenyl, R═H; A=2,4-dibenzyloxy-5-methoxyphenyl, B=1,3-benzodioxol-5-yl, R═H; A=2,4-dibenzyloxyphenyl, B=1,3-benzodioxol-5-yl, R═H; A=4-methoxyphenyl, B=2-carboxyphenyl, R═H; A=4-methylphenyl, B=2,4-dinitrophenyl, R═CH₃; A=4-hydroxy-3-methoxyphenyl, B=4-hydroxy-3-methoxyphenyl, R═H; A=2-nitrophenyl, B=4-methylphenyl, R═H; A=4-chlorophenyl, B=4-chlorophenyl, R═H; A=2,4-diacetoxyphenyl, B=phenyl, R═CH₃; A=3-methoxyphenyl, B=phenyl, R═C₂R₅; A=4-nitrophenyl, B=phenyl, R═H; A=2-nitrophenyl, B=4-n-butoxyphenyl, R═H; A=2-nitro-4-chlorophenyl, B=4-methylphenyl, R═H; A=phenyl, B=8-carboxynaphthalenyl, R═CH₃; A=2,5-dimethoxyphenyl, B=2-hydroxyphenyl, R═C₂R₅; A=4-fluorophenyl, B=2-nitro-4-trifluoromethylphenyl, R═CH₃; A=3-chloro-4-methylphenyl, B=2,4-dinitrophenyl, R═CH₃; A=2-nitro-4-chlorophenyl, B=phenyl, R═H; A=4,5-dimethoxy-2-nitrophenyl, B=4-methylphenyl, R═H; A=2-carboxy-6-nitrophenyl, B=phenyl, R═CH₃; A=2,4,5-trimethoxyphenyl, B=3-methoxyphenyl, R═H; A=phenyl, B=4-bromophenyl, R═H; A=6-benzyloxy-2,3,4-trimethoxyphenyl, B=1,3-benzodioxol-5-yl, R═H; A=4,5-dimethoxy-2-nitrophenyl, B=4-methoxyphenyl, R═H; A=4,5-dimethoxy-2-nitrophenyl, B=4-chlorophenyl, R═H; A=2,4-dibenzyloxyphenyl, B=4-methoxyphenyl, R═H; A=4-methylphenyl, B=4-methylphenyl, R═H; A=4-dimethylaminophenyl, B=phenyl, R═H; A=4-methoxyphenyl, B=phenyl, R═H; A=4,5-dichloro-2-nitrophenyl, B=4-chlorophenyl, R═H; A=2-nitrophenyl, B=4-methoxyphenyl, R═H; A=phenyl, B=2,5-dimethoxycarbonylaminophenyl, R═CH₃; A=4-hydroxy-4-methoxyphenyl, B=2-methoxyphenyl, R═H; A=phenyl, B=4-methylphenyl, R═H; A=2-nitrophenyl, B=4-ethoxyphenyl, R═H; A=2-nitro-4-chlorophenyl, B=4-methoxyphenyl, R═H; A=4-chlorophenyl, B=phenyl, R═C₂H₅; A=2-t-butoxycarbonyl-5-ethyl-4-methoxyphenyl, B=2,3-dihydro-7-methyl-1,4-benzodioxin-6-yl, R=t-butyl; A=phenyl, B=2-nitro-4-trifluoromethylphenyl, R═CH₃; A=3,4-dichlorophenyl, B=2,4-dinitrophenyl, R═CH₃; A=4,5-dichloro-2-nitrophenyl, B=4-methoxyphenyl, R═H; A=4-methoxy-2-nitrophenyl, B=4-methylphenyl, R═H; A=phenyl, B=anthracene-9-yl, R═CH₃; A=phenyl, B=4-methoxyphenyl, R═H; A=2,4,5-trimethoxyphenyl, B=phenyl, R═H; A=2,4-diacetoxyphenyl, B=2,4,5-trimethoxyphenyl, R═CH₃; A=2-hydroxyphenyl, B=phenyl, R═H; A=4-methoxy-2-nitrophenyl, B=phenyl, R═H; A=4,5-dimethoxy-2-nitrophenyl, B-phenyl, R═H; A=2,4-dinitrophenyl, B=phenyl, R═CH₃; A=phenyl, B=phenyl, R═CH₃; A=phenyl, B=4-dimethylaminophenyl, R═H; A=phenyl, B=2,4-dinitrophenyl, R═CH₃; A=4,5-dichloro-2-nitrophenyl, B=4-methylphenyl, R═H; A=4-bromophenyl, B=phenyl, R═CH₃; A=2-(4-methylphenylsulfonyloxy)-6-methoxyphenyl, B=phenyl, R═H; A=4-methylsulfonylphenyl, B=2-methoxyphenyl, R═CH₃; A=4-methoxyphenyl, B=4-methoxyphenyl, R═CH₃; A=phenyl, B=4-chlorophenyl, R═H; A=2-nitrophenyl, B=4-nitrophenyl, R═H; A=phenyl, B=phenyl, R═H; A=2,4-dimethoxyphenyl, B=4-methoxyphenyl, R═H; A=2-nitrophenyl, B=4-n-hexyloxyphenyl, R═H; A=4-methoxy-2-nitrophenyl, B=4-methoxyphenyl, R═H; A=phenyl, B=9-carboxyphenanthren-10-yl, R═CH₃; A=phenyl, B=phenyl, R═CH₃; A=3,4-dimethoxyphenyl, B=3,4-dimethoxyphenyl, R═H; A=2,4-dimethoxyphenyl, B=phenyl, R═H; A=phenyl, B=2-hydroxy-3,4,6-trimethyl-5-methoxyphenyl, R═CH₃; A=4-chloro-2-nitrophenyl, B=4-chlorophenyl, R═H; A=2-nitrophenyl, B=4-chlorophenyl, R═H; A=2,4,5-trimethoxyphenyl, B=3,4-dimethoxyphenyl, R═H; A=4-chlorophenyl, B=2,4-dinitrophenyl, R═CH₃; A=4,5-dichloro-2-nitrophenyl, B=phenyl, R═H; A=4-methoxyphenyl, B=phenyl, R═CH₃; A=2,4-dibenzyloxyphenyl, B=3,4-dimethoxyphenyl, R═H; A=4-methylthiophenyl, B=4-methoxyphenyl, R═CH₃; A=phenyl, B=phenyl, R═C₂H₅; A=4-methoxyphenyl, B=2,4-dinitrophenyl, R═CH₃; A=2-nitrophenyl, B=3-chlorophenyl, R═H; A=2-nitrophenyl, B==3,4-dimethoxyphenyl, R═H; A=4-methoxyphenyl, B=4-methoxyphenyl, R═H; A=2-hydroxyphenyl, B=4-methoxyphenyl, R═H; A=phenyl, B=2,5-bis(phenacylamino)phenyl, R═CH₃; A=4-nitrophenyl, B=4-methylphenyl, R═H; A=2-nitrophenyl, B=4-n-pentyloxyphenyl, R═H; A=4-methoxy-2-nitrophenyl, B=4-chlorophenyl, R═H; A=phenyl, B=2-carboxynaphthalen-1-yl, R═CH₃.
 2. The derivatives according to claim 1, characterized in that the compound having formula (I) are present as tautomeric and/or isomeric forms, pure or as blends of tautomeric and/or isomeric forms, in any proportion whatsoever.
 3. Use of derivatives of 1,3-diones having general formula (I):

wherein: A represents: an aryl group optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl possibly substituted with a C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl group, C₂-C₆ alkylthioalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioakyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈ alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀ alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂ dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR8R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂, -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄, —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆, -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; or represents a heterocyclic group selected from pyridyl, pyrimidyl, quinolinyl, pyrazolyl, thiazolyl, oxazolyl, thienyl, furyl, benzothienyl, dihydrobenzothienyl, benzqfuranyl, dihydrobenzofuranyl, benzoxazolyl, benzoxazolonyl, benzothiazolyl, benzothiazolonyl, benzoimidazolyl, benzoimidazolonyl, benzotriazolyl, chromanonyl, chromanyl, thiochromanonyl, thiochromanyl, 3a,4-dihydro-3H-indeno[1,2-c]isoxazolyl, 3a,4-dihydro-3H-chromeno[4,3-c]isoxazolyl, 5,5-dioxide-3a,4-dihydro-3H-thiochromeno[4,3-c]isoxazolyl, 2,3,3a,4-tetrahydrochromeno[4,3-c]pyrazolyl, 6, 6-dioxide-2,3-dihydro-5H-[1,4]dithiino[2,3-c]thiochromenyl, 5,5-dioxide-2,3,3a, 4-tetrahydrothiochromeno[4,3-c]pyrazolyl, 1′,1′-dioxide-2′,3′-dihydrospiro[1,3-dioxolane-2,4′-thiochromen]-yl, 1,1,4,4-tetraoxide-2,3-dihydro-1,4-benzodithiin-6-yl 4,4-dioxide-2,3-dihydro-1,4-benzoxathiin-7-yl, 1,1-dioxide-3-oxo-2,3-dihydro-1,2-benzoisothiazol-5-yl, 4-(alkoxyimino)-1,1-dioxide-3,4-dihydro-2H-thiochromen-6-yl, 1,1-dioxide-4-oxo-3,4-dihydro-2H-thiochromen-6-yl, 2,3-dihydro-1,4-benzoxathiin-7-yl, with all these groups possibly substituted by one or more substituents selected from halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl, possibly substituted with a C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl group, C₂-C₆ alkylthioalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈ alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀ alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂ dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂, -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄, —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆, -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; B represents a D-(R_(x))_(n) group; R represents a hydrogen atom, a linear or branched C₁-C₆ alkyl group, a linear or branched C₁-C₆ haloalkyl group, a C₃-C₆ cycloalkyl group or a C₄-C₁₂ cycloalkylalkyl group possibly substituted with halogen atoms or C₁-C₆ alkyl or C₁-C₆ thioalkyl or C₁-C₆ alkoxyl or C₂-C₆ alkoxycarbonyl groups, alkenyl C₂-C₆ groups, alkynyl C₂-C₆ groups, the latter two groups, in turn, possibly substituted with halogen atoms, a C₅-C₆ cycloalkenyl group possibly substituted with halogen atoms or C₁-C₆ alkyl groups, an aryl or arylalkyl group optionally substituted; R₁ and R₁₉, represent a C₁-C₆ alkyl or C₁-C₆ haloalkyl group, a C₃-C₆ cycloalkyl group, an aryl group optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl; m is equal to 0, 1 or 2; t is equal to 1 or 2; R₂, R₃, R₆, R₇, R₈, R₉, R₁₀, R₁₁, R₁₇ and R₁₈, the same or different, represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn possibly substituted with halogen atoms, a C₁-C₆ alkoxyl group, a C₃-C₆ cycloalkyl group, an arylalkyl group or an aryl group, said arylalkyl or aryl groups also optionally substituted with one or more stibstituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl or, together, represent a C₂-C₅ alkylenic chain; R₄, R₅ and R₄₂, represent a hydrogen atom, a linear or branched C₃-C₆ alkyl group in turn possibly substituted with halogen atoms, a C₃-C₆ alkenyl group in turn possibly substituted with halogen atoms, a Q₇ group, an arylalkyl group possibly substituted with one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl; R₁₂, R₁₄ and R₁₆, represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn possibly substituted with halogen atoms, a C₃-C₆ cycloalkyl group, a C₁-C₆ alkoxyl group, a C₁-C₆ haloalkoxyl group; R₁₃ and R₁₅, represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn possibly substituted with halogen atoms, a C₃-C₆ alkenyl group, in turn possibly substituted with halogen atoms, a Q₇ group, NH₂, NHCN, NHNH₂, NHOH, an arylalkyl group possibly substituted with one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl; R₂₀, R₂₁, R₂₂, R₂₃, R₂₄, R₂₅, R₂₆, R₂₇, R₂₈, R₂₉, R₃₀, R₃₁, R₃₂, R₃₃, R₃₄, R₃₅, R₃₆, R₃₇, R₃₈, R₃₉, R₄₀ and R₄₁, the same or different, represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn optionally substituted with halogen atoms, a C₁-C₆ alkoxyl group, or the two groups attached to the same carbon atom can be joined to each other by C₂-C₅ alkylene groups, the alkylene groups can in turn be substituted with C₁-C₃ alkyl groups; Q, Q₁, Q₂, Q₃, Q₄, Q₅, Q₆ and Q₇ represent an aryl group, a C₃-C₆ cycloalkyl group, C₅-C₆ cycloalkenyl, a heterocyclic group selected from triazolyl, triazolonyl, pyrazolyl, imidazolyl, imidazolydinonyl, tetrazolyl, tetrazolonyl, isoxazolyl, furyl, thienyl, pyrrolyl, pyrrolidinyl, pyrrolidinonyl, pyridyl, pyrimidinyl, pyrimidinonyl, pyrazinyl, pyridazinyl, oxazolyl, thiazolyl, oxadiazolyl, thiadiazolyl, isothiazolyl, benzoxazolyl, benzothiazolyl, isoxazolinyl, 1,3-dioxanyl, 1,4-dioxanyl, 1,3-dioxolanyl, tetrahydropyranyl, oxethanyl, oxyranyl, thiazolidinyl, oxazolidinyl, piperidinyl, piperidinonyl, piperazinyl, morpholinyl, thiazinyl, tetrahydrofuranyl, dioxazolyl, tetrahydrofuroisoxazolyl, 2-oxa-3-azabicyclo[3.1.0]hex-3-enyl, said groups optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl optionally substituted with a group selected from C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈ alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀ alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂ dialkylideneiminooxyalkyl, aryl optionally substituted, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO (R₁₉)₂, -Z₂(CR₃₄R₃₅)_(p)(C═Y)T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R₄₁)(C═Y)T; Z, Z₁, Z₂=O, S(O)_(r); Y═O, S; r is equal to 0, 1 or 2; p, q are equal to 1, 2, 3 or 4; v is equal to 0 or 1; Z₃=O, S or a direct bond; T represents a hydrogen atom, a Z₄R₄₂ group, a —NR₄₃R₄₄ group, an aryl group or a heterocyclic group selected from triazolyl, triazolonyl, pyrazolyl, imidazolyl, imidazolidinonyl, tetrazolyl, tetrazolonyl, pyrrolyl, pyrrolidinyl, pyrrolidinonyl, pyridyl, pyrimidinyl, piperidinyl, piperidinonyl, piperazinyl, morpholinyl, said groups optionally substituted by one or more substituents selected from halogen, NO₂, OH, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, C₃-C₆ cycloalkyl, C₅-C₆ cycloalkenyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, —S(O)_(m)R₁; Z₄=O, S or a direct bond; R₄₃ and R₄₄, the same or different, represent a hydrogen atom, a linear or branched C₁-C₆ alkyl group in turn optionally substituted with halogen atoms, a C₃-C₆ alkenyl group in turn optionally substituted with halogen atoms, a Q₇ group, an arylalkyl group optionally substituted by one or more substituents selected from halogen, NO₂, CN, CHO, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ alkylsulfonyl, C₂-C₆ alkoxycarbonyl, or they jointly represent a C₂-C₅ alkylene chain; D represents: a heterocyclic group of the heteroaryl or heterocyclic type, in all the above cases the heterocycle can be mono or polycyclic and can be connected to the rest of the structure either through one of its carbon atoms or, when possible, through one of its nitrogen atoms; or it represents a mono or polycyclic aryl group, in this latter case, the group can also be partially saturated; R_(x) represents a substituent selected from hydrogen, halogen, NO₂, CN, CHO, OH, linear or branched C₁-C₆ alkyl, linear or branched C₁-C₆ haloalkyl, linear or branched C₁-C₆ alkoxyl, linear or branched C₁-C₆ haloalkoxyl, C₁-C₆ cyanoalkyl, C₂-C₆ alkoxyalkyl, C₂-C₆ alkylthioalkyl, C₂-C₆ alkylsulfinylalkyl, C₂-C₆ alkylsulfonylalkyl, C₂-C₆ haloalkoxyalkyl, C₂-C₆ haloalkylthioalkyl, C₂-C₆ haloalkylsulfinylalkyl, C₂-C₆ haloalkylsulfonylalkyl, C₂-C₆ alkoxyalkoxyl or C₂-C₆ haloalkoxyalkoxyl optionally substituted with a group selected from C₁-C₄ alkoxyl or C₁-C₄ haloalkoxyl, C₂-C₆ alkylthioalkoxyl, C₂-C₆ haloalkylthioalkoxyl, C₃-C₁₂ dialkoxyalkyl, C₃-C₁₂ dialkylthioalkyl, C₃-C₁₂ dialkylthioalkoxyl, C₃-C₁₂ dialkoxyalkoxyl, C₂-C₆ haloalkoxyhaloalkoxyl, C₃-C₁₀ alkoxyalkoxyalkyl, C₂-C₆ alkenyl, C₂-C₆ haloalkenyl, C₂-C₆ alkenyloxy, C₂-C₆ haloalkenyloxy, C₃-C₈ alkenyloxyalkoxyl, C₃-C₈ haloalkenyloxyalkoxyl, C₂-C₆ alkynyl, C₂-C₆ haloalkynyl, C₂-C₆ alkynyloxy, C₂-C₆ haloalkynyloxy, C₃-C₈ alkynyloxyalkoxyl, C₃-C₈ haloalkynyloxyalkoxyl, C₃-C₁₂ acylaminoalkoxy, C₂-C₈ alkoxyiminoalkyl, C₂-C₈ haloalkoxyiminoalkyl, C₃-C₈ alkenyloxyiminoalkyl, C₃-C₈ haloalkenyloxyiminoalkyl, C₃-C₈ alkynyloxyiminoalkyl, C₃-C₈ haloalkynyloxyiminoalkyl, C₅-C₁₀ alkoxyalkynyloxyl, C₆-C₁₂ cycloalkylideneiminooxyalkyl, C₆-C₁₂ dialkylideneiminooxyalkyl, —S(O)_(m)R₁, —OS(O)_(t)R₁, —SO₂NR₂R₃, —CO₂R₄, —COR₅, —CONR₆R₇, —CSNR₈R₉, —NR₁₀R₁₁, —NR₁₂COR₁₃, —NR₁₄CO₂R₁₅, —NR₁₆CONR₁₇R₁₈, —PO(R₁₉)₂, -Q, -ZQ₁, —(CR₂₀R₂₁)_(p)Q₂, -Z(CR₂₂R₂₃)_(p)Q₃, —(CR₂₄R₂₅)_(p)ZQ₄, —(CR₂₆R₂₇)_(p)Z(CR₂₈R₂₉)_(q)Q₅, —(CR₃₀R₃₁)_(p)Z(CR₃₂R₃₃)_(q)Z₁Q₆, -Z₂(CR₃₄R₃₅)_(p)(C═Y) T, -Z₃(CR₃₆R₃₇)_(v)(CR₃₈R₃₉═CR₄₀R4₁)(C═Y)T; if several R_(x) groups are present, these can be the same or different; n=1-9; and of the relevant salts which have agronomical compatibility, as herbicides.
 4. Use according to claim 3, for the control under pre-emergence and post-emergence of monocotyledon and dicotyledon weeds.
 5. Use of derivatives of 1,3-diones having general formula (I):

wherein: A, B and R have the meanings defined according to claim 3, and of the relevant salts pharmaceutically acceptable as medicaments.
 6. A process for the preparation of the compounds having general formula (I) according to any of the claims 1 to 3, characterized in that it includes a reaction of a carbonyl compound having general formula (II) with a compound having general formula (III), according to the reaction scheme 1

wherein A, B and R have the meanings previously defined; L₁ represents a suitable leaving group such as, for example, a halogen atom, a CN group, an imidazol-1-yl group, an R_(L)O— group wherein R_(L) represents a C₁-C₄ alkyl group or a phenyl group optionally substituted, or it represents an R_(L1)COO— group wherein R_(L1) represents a hydrogen atom, a C₁-C₄ alkyl or haloalkyl group, a phenyl group optionally substituted or an A group.
 7. The process for the preparation of the compounds having general formula (I) according to any of the claims 1 to 3, characterized in that it includes a reaction of a carbonyl compound having general formula (IV) with a compound having general formula (V), according to the reaction scheme 2

wherein A, B and R have the meanings previously defined; L₂ represents a suitable leaving group such as, for example, a halogen atom, a CN group, an imidazol-1-yl group, an R_(L)O— group wherein R_(L) represents a C₁-C₄ alkyl group or a phenyl group optionally substituted, or it represents an R_(L1)COO— group wherein R_(L1) represents a hydrogen atom, a C₁-C₄ alkyl or haloalkyl group, a phenyl group optionally substituted or an R group.
 8. The process for the preparation of the compounds having general formula (I) according to any of the claims 1 to 3, characterized in that it includes a reaction of a 1,3-dicarbonyl compound having general formula (VI) with a compound having general formula (VII), according to the reaction scheme 3

wherein A, B and R have the meanings previously defined; X represents a halogen atom, an R_(L2)SO₂O— group, wherein R_(L2) represents a C₁-C₄ alkyl or haloalkyl group, a phenyl group optionally substituted by C₁-C₄ alkyl groups, or it represents an R_(L3)SO₂— group, wherein R_(L3) represents a C₁-C₄ alkyl or haloalkyl group.
 9. The process according to any of the claims from 6 to 8, characterized in that the reaction is carried out in the presence of one or more inert organic solvents and in the presence of an organic or inorganic base, at a temperature ranging from −80° C. to the boiling temperature of the reaction mix.
 10. The process according to claim 9, characterized in that the reaction is carried out in two separate phases.
 11. A method for the control of weeds in agricultural crops, by the application of compounds having general formula (I):

wherein: A, B and R have the meanings according to claim
 3. 12. The method according to claim 11, characterized in that the quantity of compound having formula (I) to be applied ranges from 1 g to 4,000 g per hectare.
 13. Herbicidal compositions containing, as active principle, one or more compounds having general formula (I):

wherein: A, B and R have the meanings according to claim 3, possibly also as a blend of tautomers and/or isomers.
 14. The herbicidal compositions according to claim 13, including other active principles compatible with the compounds having general formula (I), such as other herbicides, fungicides, insecticides, acaricides, fertilizers, etc.
 15. The herbicidal compositions according to claim 14, characterized in that the additional herbicides are selected from: acetochlor, acifluorfen, aclonifen, AKH-7088, alachlor, alloxydim, ametryn, amicarbazone, amidosulfuron, amitrole, anilofos, asulam, atrazine, azafenidin, azimsulfuron, aziprotryne, BAS 670 H, BAY MKH 6561, beflubutamid, benazolin, benfluralin, benfuresate, bensulfuron, bensulide, bentazone, benzfendizone, benzobicyclon, benzofenap, benzthiazuron, bifenox, bilanafos, bispyribac-sodium, bromacil, bromobutide, bromofenoxim, bromoxynil, butachlor, butafenacil, butamifos, butenachlor, butralin, butroxydim, butylate, cafenstrole, carbetamide, carfentrazone-ethyl, chlomethoxyfen, chloramben, chlorbromuron, chlorbufam, chlorflurenol, chloridazon, chlorimuron, chlornitrofen, chlorotoluron, chloroxuron, chlorpropham, chlorsulfuron, chlorthal, chlorthiamid, cinidon ethyl, cinmethylin, cinosulfuron, clethodim, clodinafop, clomazone, clomeprop, clopyralid, cloransulam-methyl, cumyluron (JC-940), cyanazine, cycloate, cyclosulfamuron, cycloxydim, cyhalofop-butyl, 2,4-D, 2,4-DB, daimuron, dalapon, desmedipham, desmetryn, dicamba, dichlobenil, dichlorprop, dichlorprop-P, diclofop, diclosulam, diethatyl, difenoxuron, difenzoquat, diflufenican, diflufenzopyr, dimefuron, dimepiperate, dimethachlor, dimethametryn, dimethenamid, dinitramine, dinosseb, dinoseb acetate, dinoterb, diphenamid, dipropetryn, diquat, dithiopyr, 1-diuron, eglinazine, endothal, EPTC, espropcarb, ethalfluralin, ethametsulfuron-methyl, ethidimuron, ethiozin (SMY 1500), ethofumesate, ethoxyfen-ethyl (HC-252), ethoxysulfuron, etobenzanid (HW 52), fenoxaprop, fenoxaprop-P, fentrazamide, fenuron, flamprop, flamprop-M, flazasulfuron, florasulam, fluazifop, fluazifop-P, fluazolate (JV 485), flucarbazone-sodium, fluchloralin, flufenacet, flufenpyr ethyl, flumetsulam, flumiclorac-pentyl, flumioxazin, flumipropin, fluometuron, fluoroglycofen, fluoronitrofen, flupoxam, fluproanate, flupyrsulfuron, flurenol, fluridone, flurochloridone, fluroxypyr, flurtamone, fluthiacet-methyl, fomesafen, foramsulfuron, fosamine, furyloxyfen, glufosinate, glyphosate, halosulfuron-methyl, haloxyfop, haloxyfop-P-methyl, hexazinone, imazamethabenz, imazamox, imazapic, imazapyr, imazaquin, imazethapyr, imazosulfuron, indanofan, iodosulfuron, ioxynil, isopropalin, isoproturon, isouron, isoxaben, isoxachlortole, isoxaflutole, isoxapyrifop, KPP-421, lactofen, lenacil, linuron, LS830556, MCPA, MCPA-thioethyl, MCPB, mecoprop, mecoprop-P, mefenacet, mesosulfuron, mesotrione, metamitron, metazachlor, methabenzthiazuron, methazole, methoprotryne, methyldymron, metobenzuron, metobromuron, metolachlor, S-metolachlor, metosulam, metoxuron, metribuzin, metsulfuron, molinate, monalide, monolinuron, naproanilide, napropamide, naptalam, NC-330, neburon, nicosulfuron, nipyraclofen, norflurazon, orbencarb, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone, oxyfluorfen, paraquat, pebulate, pendimethalin, penoxsulam, pentanochlor, pentoxazone, pethoxamid, phenmedipham, picloram, picolinafen, piperophos, pretilachlor, primisulfuron, prodiamine, profluazol, proglinazine, prometon, prometryne, propachlor, propanil, propaquizafop, propazine, propham, propisochlor, propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraflufen-ethyl, pyrazogyl (HAS-961), pyrazolynate, pyrazosulfuron, pyrazoxyfen, pyribenzoxim, pyributicarb, pyridafol, pyridate, pyriftalid, pyriminobac-methyl, pyrithiobac-sodium, quinclorac, quinmerac, quizalofop, quizalofop-P, rimsulfuron, sethoxydim, siduron, simazine, simetryn, sulcotrione, sulfentrazone, sulfometuron-methyl, sulfosulfuron, 2,3,6-TBA, TCA-sodium, tebutam, tebuthiuron, tepraloxydim, terbacil, terbumeton, terbuthyl-azine, terbutryn, thenylchlor, thiazafluron, thiazopyr, thidiazimin, thifensulfuron-methyl, thiobencarb, tiocarbazil, tioclorim, tralkoxydim, tri-allate, triasulfuron, triaziflam, tribenuron, triclopyr, trietazine, trifloxysulfuron, trifluralin, triflusulfuron-methyl, tritosulfuron, UBI-C4874, vernolate.
 16. The compositions according to any of the claims 13-15, characterized in that the concentration of active substance ranges from 1 to 90%. 